Dan Li

Summary

Affiliation: China Medical University
Country: China

Publications

  1. doi request reprint Nrf2-mediated adaptive response to methyl glyoxal in HepG2 cells involves the induction of AKR7A2
    Dan Li
    Department of Biopharmaceuticals, School of Pharmacy, China Medical University, Heping District, Shenyang 110001, China Electronic address
    Chem Biol Interact 234:366-71. 2015
  2. doi request reprint 4-Hydroxynonenal induces an increase in expression of Receptor for Activating C Kinase 1 (RACK1) in Chinese hamster V79-4 lung cells
    Dan Li
    Department of Biopharmaceuticals, School of Pharmacy, China Medical University, Shenyang 110001, PR China Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, 161 Cathedral Street, Glasgow G4 0RE, United Kingdom Electronic address
    Chem Biol Interact 213:13-20. 2014
  3. doi request reprint Aldo-keto reductase 7A5 (AKR7A5) attenuates oxidative stress and reactive aldehyde toxicity in V79-4 cells
    Dan Li
    Department of Biopharmaceuticals, School of Pharmacy, China Medical University, Heping District, Shenyang 110001, China Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, 161 Cathedral Street, Glasgow G4 0RE, United Kingdom Electronic address
    Toxicol In Vitro 28:707-14. 2014
  4. doi request reprint Inducible protection of human astrocytoma 1321N1 cells against hydrogen peroxide and aldehyde toxicity by 7-hydroxycoumarin is associated with the upregulation of aldo-keto reductases
    Dan Li
    School of Pharmaceutical Sciences, China Medical University, Heping District, Shenyang 110001, China
    Neurotoxicology 33:1368-74. 2012
  5. ncbi request reprint [Effect of AKR1A1 knock-down on H2;O2; and 4-hydroxynonenal-induced cytotoxicity in human 1321N1 astrocytoma cells]
    Dan Li
    School of Pharmacy, China Medical University, Shenyang, China
    Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 29:273-6. 2013
  6. doi request reprint Aldo-keto reductases mediate constitutive and inducible protection against aldehyde toxicity in human neuroblastoma SH-SY5Y cells
    Robert C Lyon
    Strathclyde Institute of Pharmacy and Biomedical Sciences, 161 Cathedral Street, University of Strathclyde, Glasgow G4 0RE, Scotland, UK
    Neurochem Int 62:113-21. 2013
  7. ncbi request reprint [Effect of AKR7A1 overexpression on crotonaldehyde-induced mutagenicity in V79-4 cells]
    Dan Li
    School of Pharmaceutical Sciences, China Medical University, Shenyang, China
    Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 28:1013-5. 2012
  8. doi request reprint Preparation and in vitro evaluation of glycyrrhetinic acid-modified curcumin-loaded nanostructured lipid carriers
    Yang Chu
    Department of Pharmacy, The First Affiliated Hospital of China Medical University, 155 Nanjing Street, Shenyang 110001, China
    Molecules 19:2445-57. 2014

Collaborators

Detail Information

Publications8

  1. doi request reprint Nrf2-mediated adaptive response to methyl glyoxal in HepG2 cells involves the induction of AKR7A2
    Dan Li
    Department of Biopharmaceuticals, School of Pharmacy, China Medical University, Heping District, Shenyang 110001, China Electronic address
    Chem Biol Interact 234:366-71. 2015
    ..Nrf2 is critical in mediating MG induced expression of protective genes...
  2. doi request reprint 4-Hydroxynonenal induces an increase in expression of Receptor for Activating C Kinase 1 (RACK1) in Chinese hamster V79-4 lung cells
    Dan Li
    Department of Biopharmaceuticals, School of Pharmacy, China Medical University, Shenyang 110001, PR China Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, 161 Cathedral Street, Glasgow G4 0RE, United Kingdom Electronic address
    Chem Biol Interact 213:13-20. 2014
    ..The results from this study provide new information on the mechanism of adaptive stress response to HNE and also identify potential new biomarkers of exposure to HNE...
  3. doi request reprint Aldo-keto reductase 7A5 (AKR7A5) attenuates oxidative stress and reactive aldehyde toxicity in V79-4 cells
    Dan Li
    Department of Biopharmaceuticals, School of Pharmacy, China Medical University, Heping District, Shenyang 110001, China Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, 161 Cathedral Street, Glasgow G4 0RE, United Kingdom Electronic address
    Toxicol In Vitro 28:707-14. 2014
    ..These findings indicate the importance of AKR7A5 in protecting cells from the damaging effects of oxidative stress, and that this cytoprotective function is carried out through multiple pathways...
  4. doi request reprint Inducible protection of human astrocytoma 1321N1 cells against hydrogen peroxide and aldehyde toxicity by 7-hydroxycoumarin is associated with the upregulation of aldo-keto reductases
    Dan Li
    School of Pharmaceutical Sciences, China Medical University, Heping District, Shenyang 110001, China
    Neurotoxicology 33:1368-74. 2012
    ..These results indicate the importance of AKR family members in the detoxication of aldehydes, and also show that the natural phytochemical 7-hydroxycoumarin is a potential therapeutic candidate for neurodegenerative diseases...
  5. ncbi request reprint [Effect of AKR1A1 knock-down on H2;O2; and 4-hydroxynonenal-induced cytotoxicity in human 1321N1 astrocytoma cells]
    Dan Li
    School of Pharmacy, China Medical University, Shenyang, China
    Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 29:273-6. 2013
    ..To investigate the role of human aldo-keto reductase 1A1 (AKR1A1) in the resistance to oxidative stress and the metabolism of toxic aldehyde in astrocytoma cells...
  6. doi request reprint Aldo-keto reductases mediate constitutive and inducible protection against aldehyde toxicity in human neuroblastoma SH-SY5Y cells
    Robert C Lyon
    Strathclyde Institute of Pharmacy and Biomedical Sciences, 161 Cathedral Street, University of Strathclyde, Glasgow G4 0RE, Scotland, UK
    Neurochem Int 62:113-21. 2013
    ....
  7. ncbi request reprint [Effect of AKR7A1 overexpression on crotonaldehyde-induced mutagenicity in V79-4 cells]
    Dan Li
    School of Pharmaceutical Sciences, China Medical University, Shenyang, China
    Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 28:1013-5. 2012
    ..To investigate the effect of overexpressing rat aldo-keto reductases (AKR7A1) in V79-4 cells on crotonaldehyde-induced mutagenicity...
  8. doi request reprint Preparation and in vitro evaluation of glycyrrhetinic acid-modified curcumin-loaded nanostructured lipid carriers
    Yang Chu
    Department of Pharmacy, The First Affiliated Hospital of China Medical University, 155 Nanjing Street, Shenyang 110001, China
    Molecules 19:2445-57. 2014
    ..06%-95.31% and particle size was between 123.1 nm and 132.7 nm. An in vitro MTT assay showed that Cur-GA10%-PEG-NLC had significantly high cellular uptake and cytotoxicity against HepG2 cells compared with other groups. ..