Xin Chen

Summary

Country: China

Publications

  1. ncbi Effect of Radix Isatidis on the expression of moesin mRNA induced by LPS in the tissues of mice
    Jing Li
    Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
    J Huazhong Univ Sci Technolog Med Sci 27:135-7. 2007
  2. ncbi Rapid effects of simvastatin on lipid profile and C-reactive protein in patients with hypercholesterolemia
    Jian Jun Li
    Department of Cardiology, Renmin Hospital, Wuhan University School of Medicine, Wuhan, People s Republic of China
    Clin Cardiol 26:472-6. 2003
  3. ncbi Thoracic cord compression caused by contiguous multilevel ossification of ligamentum flavum in Chinese patients
    Kai Wang
    Department of Orthopedic Surgery, Second Affiliated Hospital, Tianjin Medical University, Tianjin 300211, China
    Chin J Traumatol 10:213-7. 2007
  4. ncbi Clinical features of hereditary spastic paraplegia with thin corpus callosum: report of 5 Chinese cases
    Bei sha Tang
    Department of Neurology, Xiangya Hospital, Central Southern University, Changsha 410008, China
    Chin Med J (Engl) 117:1002-5. 2004
  5. pmc Evaluation of preoperative intra-aortic balloon pump in coronary patients with severe left ventricular dysfunction undergoing OPCAB surgery: early and mid-term outcomes
    Zhibing Qiu
    Department of Thoracic and Cardiothoracic Surgery, Nanjing First Hospital Affiliated to Nanjing Medical University, Nanjing Heart Institute, 210006 Nanjing, PR China
    J Cardiothorac Surg 4:39. 2009
  6. ncbi [Maternal factors affecting development of early mouse embryos]
    Chun Li Zhao
    State Key Laboratory of Reproductive Biology, Institute of Zoology, The Chinese Academy of Sciences, Beijing 100080, China
    Yi Chuan 28:601-5. 2006
  7. ncbi A pedigree analysis of familial hypercholesterolemia in monozygote twin brothers
    Jian Jun Li
    Department of Cardiology, Renmin Hospital, Wuhan University School of Medicine, Wuhan, People s Republic of China
    Angiology 54:711-3. 2003
  8. ncbi Is the use of cardiopulmonary bypass for isolated coronary artery bypass an independent predictor of mortality and morbidity in patients with severe left ventricular dysfunction?
    Zhi bing Qiu
    Department of Cardiothoracic Surgery, Nanjing First Hospital Affiliated to Nanjing Medical University, Nanjing Heart Institute, Nanjing, Jiangsu 210006, China
    Chin Med J (Engl) 121:2397-402. 2008
  9. ncbi [Clinical features and treatment of traumatic cervical disc herniation]
    Xin Chen
    Department of Orthopaedics, First Affiliated Hospital of Wenzhou Medical College, Wenzhou 325000, Zhejiang, China
    Zhongguo Gu Shang 21:924-5. 2008
  10. ncbi [The research of relationship between DNA degradation and postmortem interval]
    Xin Chen
    Shanghai Institute of Criminal Science and Technology, Shanghai 200083, China
    Fa Yi Xue Za Zhi 21:115-7. 2005

Collaborators

Detail Information

Publications61

  1. ncbi Effect of Radix Isatidis on the expression of moesin mRNA induced by LPS in the tissues of mice
    Jing Li
    Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
    J Huazhong Univ Sci Technolog Med Sci 27:135-7. 2007
    ..Our study showed that F(022) part from Radix Isatidis can inhibit the LPS-induced expression of moesin mRNA in the tissues of liver, kidney and spleen in mice...
  2. ncbi Rapid effects of simvastatin on lipid profile and C-reactive protein in patients with hypercholesterolemia
    Jian Jun Li
    Department of Cardiology, Renmin Hospital, Wuhan University School of Medicine, Wuhan, People s Republic of China
    Clin Cardiol 26:472-6. 2003
    ..Limited information has been available in evaluating a potentially effective first 2-week therapeutic approach for the treatment of patients with hypercholesterolemia using a statin...
  3. ncbi Thoracic cord compression caused by contiguous multilevel ossification of ligamentum flavum in Chinese patients
    Kai Wang
    Department of Orthopedic Surgery, Second Affiliated Hospital, Tianjin Medical University, Tianjin 300211, China
    Chin J Traumatol 10:213-7. 2007
    ..To explore the epidemiology, clinical presentation, radiology and surgical treatment outcome in Chinese patients with myelopathy caused by contiguous multilevel ossification of ligamentum flavum...
  4. ncbi Clinical features of hereditary spastic paraplegia with thin corpus callosum: report of 5 Chinese cases
    Bei sha Tang
    Department of Neurology, Xiangya Hospital, Central Southern University, Changsha 410008, China
    Chin Med J (Engl) 117:1002-5. 2004
    ..This study was conducted to investigate the clinical features of hereditary spastic paraplegia with thin corpus callosum (HSP-TCC)...
  5. pmc Evaluation of preoperative intra-aortic balloon pump in coronary patients with severe left ventricular dysfunction undergoing OPCAB surgery: early and mid-term outcomes
    Zhibing Qiu
    Department of Thoracic and Cardiothoracic Surgery, Nanjing First Hospital Affiliated to Nanjing Medical University, Nanjing Heart Institute, 210006 Nanjing, PR China
    J Cardiothorac Surg 4:39. 2009
    ....
  6. ncbi [Maternal factors affecting development of early mouse embryos]
    Chun Li Zhao
    State Key Laboratory of Reproductive Biology, Institute of Zoology, The Chinese Academy of Sciences, Beijing 100080, China
    Yi Chuan 28:601-5. 2006
    ..This indicates the oocyte cytoplasm plays a critical role in the development of reconstructed embryos...
  7. ncbi A pedigree analysis of familial hypercholesterolemia in monozygote twin brothers
    Jian Jun Li
    Department of Cardiology, Renmin Hospital, Wuhan University School of Medicine, Wuhan, People s Republic of China
    Angiology 54:711-3. 2003
    ..This pedigree analysis showed that FH appears to be a hereditary disease of autosomal dominance, and attention should be paid, especially in the only son or daughter society of China...
  8. ncbi Is the use of cardiopulmonary bypass for isolated coronary artery bypass an independent predictor of mortality and morbidity in patients with severe left ventricular dysfunction?
    Zhi bing Qiu
    Department of Cardiothoracic Surgery, Nanjing First Hospital Affiliated to Nanjing Medical University, Nanjing Heart Institute, Nanjing, Jiangsu 210006, China
    Chin Med J (Engl) 121:2397-402. 2008
    ..The aim of this study was to assess the risk factors responsible for mortality and morbidity among patients with SLVD by comparing CCABG and off-pump coronary artery bypass surgery (OPCAB)...
  9. ncbi [Clinical features and treatment of traumatic cervical disc herniation]
    Xin Chen
    Department of Orthopaedics, First Affiliated Hospital of Wenzhou Medical College, Wenzhou 325000, Zhejiang, China
    Zhongguo Gu Shang 21:924-5. 2008
    ..To investigate clinical features of the traumatic cervical disc herniation and through retrospective analysis 62 cases of traumatic cervical disc herniation...
  10. ncbi [The research of relationship between DNA degradation and postmortem interval]
    Xin Chen
    Shanghai Institute of Criminal Science and Technology, Shanghai 200083, China
    Fa Yi Xue Za Zhi 21:115-7. 2005
    ..To investigate the relationship between the DNA degradation in cells and postmortem interval...
  11. ncbi [Investigate the relationship between postmortem interval (PMI) and the metabolic law of the amount of DNA in cells of rat]
    Zhi Ping Liu
    Department of Forensic Medicine, Medical Center of Fudan University, Shanghai 200032, China
    Fa Yi Xue Za Zhi 20:68-9. 2004
    ..To investigate the relationship between postmortem interval (PMI) and the metabolic law of the amount of DNA in cells...
  12. pmc Subcellular transport of EKLF and switch-on of murine adult beta maj globin gene transcription
    Yu Chiau Shyu
    Institute of Molecular Biology, Academia Sinica, Nankang, Taipei 115, Taiwan, Republic of China
    Mol Cell Biol 27:2309-23. 2007
    ....
  13. ncbi Oldhamiphylline A: a novel hexacyclic alkaloid from Daphniphyllum oldhami
    Xin Chen
    State Key Laboratory of Drug Research, Institute of Materia Medica, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 555 Zu Chong Zhi Road, Zhangjiang Hi Tech Park, Shanghai, 201203, PR China
    Chem Biodivers 1:1513-8. 2004
    ..The structure of 1 was established by spectroscopic methods, especially 2D NMR techniques (1H,1H-COSY, HMQC, HMBC, and NOESY)...
  14. ncbi A general framework for biclustering gene expression data
    Haifeng Li
    Center of Excellence in Genomic Science, University of Southern California, Los Angeles, CA 90089, USA
    J Bioinform Comput Biol 4:911-33. 2006
    ..The preliminary experiments on simulated as well as real data show that our approach is very versatile and promising...
  15. pmc Organic cation transporters are determinants of oxaliplatin cytotoxicity
    Shuzhong Zhang
    Department of Biopharmaceutical Sciences, Comprehensive Cancer Center, University of California at San Francisco, San Francisco, CA 94158, USA
    Cancer Res 66:8847-57. 2006
    ..The development of new anticancer drugs, specifically targeted to OCTs, represents a novel strategy for targeted drug therapy. The results of the present structure-activity studies indicate specific tactics for realizing this goal...
  16. ncbi Lipopolysaccharide found in aseptic loosening of patients with inflammatory arthritis
    Jennifer L Nalepka
    Departments of Orthopaedics, Case Western Reserve University, University Hospitals of Cleveland, Cleveland, OH, USA
    Clin Orthop Relat Res 451:229-35. 2006
    ..Endotoxins derived from low-grade or systemic bacteremia may be important contributors to aseptic loosening particularly in patients with autoimmune conditions such as inflammatory arthritis...
  17. pmc Triptolide, a constituent of immunosuppressive Chinese herbal medicine, is a potent suppressor of dendritic-cell maturation and trafficking
    Xin Chen
    Basic Research Program, Science Applications International Corporation Frederick, Inc, Laboratory of Molecular Immunoregulation, National Cancer Institute Frederick, Frederick, MD 21702 1201, USA
    Blood 106:2409-16. 2005
    ..These data provide new insight into the mechanism of action of TPT and indicate that the inhibition of maturation and trafficking of DCs by TPT contributes to its immunosuppressive effects...
  18. ncbi Chromatin-binding in vivo of the erythroid kruppel-like factor, EKLF, in the murine globin loci
    Yu Chiau Shyu
    Institute of Molecular Biology, Academia Sinica, Nankang, Taipei 115
    Cell Res 16:347-55. 2006
    ....
  19. ncbi [Allelopathic effects of invasive weed Solidago canadensis on native plants]
    Lingxiao Mei
    College of Life Sciences, Zhejiang University, Hangzhou 310029, China
    Ying Yong Sheng Tai Xue Bao 16:2379-82. 2005
    ....
  20. ncbi [Beyond the numerals: primary reports from Registry of PCI In China (ROPIC)]
    Shu Zheng Lu
    Department of Cardiology, Capital University of Medical Sciences Affiliated Beijing Anzhen Hospital, Beijing 100029, China
    Zhonghua Xin Xue Guan Bing Za Zhi 34:966-70. 2006
    ..The purpose of this registry is to collect data on percutaneous coronary interventions (PCI) performed in various provinces in mainland China in 2005...
  21. ncbi Safety and efficacy of the CYPHER Select Sirolimus-eluting stent in the "Real World"--clinical and angiographic results from the China CYPHER Select registry
    Run lin Gao
    Chinese Society of Cardiology, China
    Int J Cardiol 125:339-46. 2008
    ..This post-marketing surveillance registry is aimed at determining the safety and reliability of the CYPHER Select Sirolimus-eluting stent (SES) in routine clinical practice...
  22. pmc Stimulation of macrophage TNFalpha production by orthopaedic wear particles requires activation of the ERK1/2/Egr-1 and NF-kappaB pathways but is independent of p38 and JNK
    Michelle A Beidelschies
    Department of Physiology and Biophysics, Case Medical Center, Case Western Reserve University, Cleveland, Ohio 44106, USA
    J Cell Physiol 217:652-66. 2008
    ....
  23. doi Design and evaluation of sifuvirtide, a novel HIV-1 fusion inhibitor
    Yuxian He
    AIDS Research Center, Institute of Pathogen Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China
    J Biol Chem 283:11126-34. 2008
    ..0 +/- 8.6 h and 26.0 +/- 7.9 h, respectively. In summary, sifuvirtide has potential to become an ideal fusion inhibitor for treatment of HIV/AIDS patients, including those with HIV-1 strains resistant to T20...
  24. doi Inhibitory effects of ginsenosides from the root of Panax ginseng on stimulus-induced superoxide generation, tyrosyl or serine/threonine phosphorylation, and translocation of cytosolic compounds to plasma membrane in human neutrophils
    Wenfei He
    Department of Anesthesiology and Critical Care Medicine, Kochi Medical School, Nankoku City, Kochi, Japan
    J Agric Food Chem 56:1921-7. 2008
    ..FMLP-, PMA-, and AA-induced tyrosyl or serine/threonine phosphorylation and translocation of p47phox, p67phox, and Rac to the plasma membrane were in parallel with the suppression of the stimulus-induced superoxide generation...
  25. doi Integration of genomic analysis and in vivo transfection to identify sprouty 2 as a candidate tumor suppressor in liver cancer
    Susie A Lee
    Department of Biopharmaceutical Sciences, University of California, San Francisco, CA 94143, USA
    Hepatology 47:1200-10. 2008
    ..In addition, we demonstrate that the integration of genomic analysis and in vivo transfection is a powerful tool to identify genes that are important during hepatic carcinogenesis...
  26. ncbi [Regulation effects of arbuscular mycorrhizal fungi on the interactions between barnyard grass and upland rice under enhanced nitrogen supply]
    Sheng Chao Zhu
    Department of Biology, Lishui College, Lishui 323000, Zhejiang, China
    Ying Yong Sheng Tai Xue Bao 18:2337-42. 2007
    ..sativa to E. crus-galli increased in treatment without AMF inoculation but decreased in treatment with AMF inoculation. It was suggested that AMF tended to enhance the competition of E. crus-galli to O. sativa under enhanced N supply...
  27. ncbi Iridoid glycosyl esters from Scrophularia ningpoensis
    Xin Chen
    Department of Biotechnology and Chemical Engineering, Wuhan Polytechnic University, Hubei, 430023 PR, China
    Nat Prod Res 21:1187-90. 2007
    ..The structure of scrophulninoside A (1) was elucidated by spectroscopic methods...
  28. ncbi Learning the drug target-likeness of a protein
    Huan Xu
    College of Life Science, Zhejiang University, Zijinhua Road, Hangzhou, Zhejiang, P R China
    Proteomics 7:4255-63. 2007
    ....
  29. ncbi Appearance of segmental discrepancy of anion transport in rat distal colon
    Hong Xue
    Department of Physiology, Basic Medical College, Capital Medical University, Beijing 100069, China
    Biol Pharm Bull 30:1407-11. 2007
    ..HCO(3)(-) might be predominantly involved in the forskolin-induced anion secretion in DC(1), but Cl(-) might be the main component of the anion secretion in DC(4)...
  30. ncbi Inverse expression of Jun activation domain binding protein 1 and cell cycle inhibitor p27Kip1: influence on proliferation in hepatocellular carcinoma
    Jan P Berg
    Institute of Pathology, University of Bonn, D 53127 Bonn, Germany
    Hum Pathol 38:1621-7. 2007
    ..We conclude that Jab1 expression may lead to down-regulation of the negative cell cycle regulator p27(Kip1), pointing to a possible mechanism that promotes hepatocarcinogenesis...
  31. pmc Splenic CD19-CD35+B220+ cells function as an inducer of follicular dendritic cell network formation
    Takaya Murakami
    Laboratory for Epithelial Immunobiology, Rikagaku Kenkyusho RIKEN Research Center for Allergy and Immunology, Yokohama, Japan
    Blood 110:1215-24. 2007
    ....
  32. ncbi Decoding global gene expression programs in liver cancer by noninvasive imaging
    Eran Segal
    Dept of Computer Science and Applied Mathematics, Weizmann Institute of Science, Rehovot 76100, Israel
    Nat Biotechnol 25:675-80. 2007
    ..Thus, genomic activity of human liver cancers can be decoded by noninvasive imaging, thereby enabling noninvasive, serial and frequent molecular profiling for personalized medicine...
  33. pmc Pertussis toxin as an adjuvant suppresses the number and function of CD4+CD25+ T regulatory cells
    Xin Chen
    Basic Research Program, SAIC Frederick, Inc, Laboratory of Molecular Immunoregulation, National Cancer Institute Frederick Frederick, MD 21702 1201, USA
    Eur J Immunol 36:671-80. 2006
    ..This study concludes that an underlying cause for the immunological adjuvanticity of PTx is down-regulation of Treg cell number and function...
  34. pmc TiProD: the Tissue-specific Promoter Database
    Xin Chen
    Centre of Bioinformatics, College of Life Sciences, National Laboratory of Protein Engineering and Plant Genetic Engineering, Peking University, Beijing 100871, China
    Nucleic Acids Res 34:D104-7. 2006
    ..We have defined a measure for tissue-specificity that allows the user to discriminate between ubiquitously and specifically expressed genes. The database is accessible at http://tiprod.cbi.pku.edu.cn:8080/index.html...
  35. ncbi Array-based comparative genomic hybridization reveals recurrent chromosomal aberrations and Jab1 as a potential target for 8q gain in hepatocellular carcinoma
    Mohini A Patil
    Department of Biopharmaceutical Sciences, University of California, San Francisco, CA 94143, USA
    Carcinogenesis 26:2050-7. 2005
    ....
  36. ncbi [Estimation of postmortal interval by measuring the amount of DNA in cells]
    Xin Chen
    Shanghai Criminal Science and Technology Institute, Shanghai 200083, China
    Fa Yi Xue Za Zhi 19:120-1. 2003
    ..This paper introduce several different measuring ways, law of variation and application situation of DNA in cells. In addition, the result evaluation of measuring methods and application prospect is given...
  37. ncbi [The epidemiology of neural tube defects in high-prevalence and low-prevalence areas of China]
    Li Jun Pei
    Institute of Reproductive and Child Health, Peking University, Beijing 100083, China
    Zhonghua Liu Xing Bing Xue Za Zhi 24:465-70. 2003
    ..To describe the epidemiology of neural tube defects (NTDs) in high- and low-prevalence areas of China...
  38. pmc Phospholipase A2 group IIA expression in gastric adenocarcinoma is associated with prolonged survival and less frequent metastasis
    Suet Y Leung
    Departments of Pathology and Surgery, University of Hong Kong, Hong Kong, China
    Proc Natl Acad Sci U S A 99:16203-8. 2002
    ..Beyond its potential diagnostic and prognostic significance, this result suggests the intriguing possibility that the activity of PLA2G2A may suppress progression or metastasis of human gastric cancer...
  39. ncbi [Characteristics of nitrogen loss from sloping field in red soil area under different cultivation practices]
    Donghai Yuan
    Institute of Agroecology, Zhejiang University, Hangzhou 310029
    Ying Yong Sheng Tai Xue Bao 13:863-6. 2002
    ..Dissolved nitrogen was the major form of lost nitrogen and accounted for 78-87.6% of total lost nitrogen in runoff. Nitrogen loss was occurred mainly during May to August, and it accounted for 85-100% of total annual nitrogen loss...
  40. ncbi Termination of immediate-early gene expression after stimulation by parathyroid hormone or isoproterenol
    Xin Chen
    Department of Orthopaedics, Case Western Reserve University and University Hospitals of Cleveland, Cleveland, Ohio 44106 5000, USA
    Am J Physiol Cell Physiol 283:C1432-40. 2002
    ..This conclusion may therefore reflect a general mechanism for termination of immediate-early gene expression after induction by cAMP/PKA...
  41. ncbi Contribution of endothelin-1 to renal activator protein-1 activation and macrophage infiltration in aldosterone-induced hypertension
    Rita C A Tostes
    Department of Pharmacology, Instituto de Ciencias Biomedicas, Univeridade de Sao Paulo, Av Lineu Prestes 1524, Sao Paulo 05508 900, Brazil
    Clin Sci (Lond) 103:25S-30S. 2002
    ..These processes were attenuated by BMS 182874. Our findings suggest that renal damage in aldosterone-dependent hypertension is associated with inflammatory processes that are mediated in part via ET-1...
  42. ncbi Bioactive abietane and seco-abietane diterpenoids from Salvia prionitis
    Xin Chen
    Shanghai Institute of Materia Medica, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 294 Tai Yuan Road, Shanghai 200031, People s Republic of China
    J Nat Prod 65:1016-20. 2002
    ..8 microM. Compound 5 exhibited cytotoxic activities against HL-60 human leukemia and the SGC-7901 and MKN-28 stomach cancer cell lines, with IC50 values of 4.6, 0.2, and 0.3 microM, respectively...
  43. ncbi Changes of sarcoplamic reticular Ca(2+)-ATPase and IP(3)-I receptor mRNA expression in patients with atrial fibrillation
    Kejiang Cao
    Department of Cardiology, The First Affiliated Hospital, Nanjing Medical University, Nanjing 210029, China
    Chin Med J (Engl) 115:664-7. 2002
    ..To investigate changes in the expression of sarcoplamic reticular Ca(2+)-ATPase (SERCA) and IP(3)-I receptors (IP(3)R(1)) mRNA in patients with atrial fibrillation...
  44. ncbi [The effects of interleukin-12 inhalation on airway inflammation and T helper cell subsets in mouse asthma models]
    Xin Chen
    Respiratory Department of China Japan Friendship Hospital, Beijing 100029, China
    Zhonghua Nei Ke Za Zhi 41:313-6. 2002
    ..To observe the effects of aerosol interleukin-12 (IL-12) on the antigen-induced airway inflammation and T helper cell subsets in mouse asthma models...
  45. pmc Gene expression patterns in human liver cancers
    Xin Chen
    Department of Biochemistry, Stanford University School of Medicine, Stanford, California 94305, USA
    Mol Biol Cell 13:1929-39. 2002
    ..Some features of the gene expression patterns were associated with specific phenotypic and genotypic characteristics of the tumors, including growth rate, vascular invasion, and p53 overexpression...
  46. ncbi [The establishment and application of antiviral screening model targeted on SAH hydrolase]
    Tian Zhang
    Institute of Medicinal Biotechnology and Institute of Materia Medica CAMS and PUMC, Beijing 100050, China
    Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi 16:55-8. 2002
    ..To establish a SAH hydrolase antiviral screening in vitro model for screening of broad spectrum antiviral agents...
  47. ncbi Tannic acid is an inhibitor of CXCL12 (SDF-1alpha)/CXCR4 with antiangiogenic activity
    Xin Chen
    The Basic Research Program, Science Applications International Corporation Frederick, Inc Gaithersburg, Maryland 20879, USA
    Clin Cancer Res 9:3115-23. 2003
    ..The antiangiogenic effect of tannic acid was assessed by in vitro endothelial cell tube formation...
  48. pmc Shikonin, a component of chinese herbal medicine, inhibits chemokine receptor function and suppresses human immunodeficiency virus type 1
    Xin Chen
    Basic Research Program, SAIC Frederick, Inc, National Cancer Institute Frederick, Frederick, Maryland 21702 1201, USA
    Antimicrob Agents Chemother 47:2810-6. 2003
    ..Therefore, shikonin, as a naturally occurring, low-molecular-weight pan-chemokine receptor inhibitor, constitutes a basis for the development of novel anti-HIV therapeutic agents...
  49. ncbi Can an in silico drug-target search method be used to probe potential mechanisms of medicinal plant ingredients?
    Xin Chen
    Department of Computational Science, National University of Singapore, Blk S17, Level 7, 3 Science Drive 2, Singapore 117543
    Nat Prod Rep 20:432-44. 2003
    ....
  50. ncbi Arbuscular mycorrhizae enhance metal lead uptake and growth of host plants under a sand culture experiment
    Xin Chen
    College of Life Sciences, Zhejiang University, No 268, Kaixuan Road, Hangzhou, Zhejiang 310029, PR China
    Chemosphere 60:665-71. 2005
    ..We suggest that under an elevated Pb condition, mycorrhizae could promote plant growth by increasing P uptake and mitigate Pb toxicity by sequestrating more Pb in roots...
  51. ncbi Effects of Shuanghuanglian and Qingkailing, two multi-components of traditional Chinese medicinal preparations, on human leukocyte function
    Xin Chen
    Laboratory of Molecular Immunoregulation, Center for Cancer Research, National Cancer Institute Frederick, Fort Detrick, MD, 21702 1201, USA
    Life Sci 70:2897-913. 2002
    ..Identification of the responsible components in these two herbal preparations may yield compounds suitable for structural modification into potent novel drugs...
  52. ncbi [Influence of elevated atmospheric CO2 on rhizosphere microbes and arbuscular mycorrhizae]
    Jing Chen
    College of Life Sciences, Zhejiang University, Hangzhou, China
    Ying Yong Sheng Tai Xue Bao 15:2388-92. 2004
    ....
  53. ncbi Triptolide attenuates endotoxin- and staphylococcal exotoxin-induced T-cell proliferation and production of cytokines and chemokines
    Teresa Krakauer
    Department of Immunology and Molecular Biology, United States Army Medical Research Institute of Infectious Diseases, Bldg 1425, Fort Detrick, Frederick, MD 21702 5011, USA
    Immunopharmacol Immunotoxicol 27:53-66. 2005
    ..It also may be therapeutically useful for mitigating the pathogenic effects of these microbial products by downregulating the signaling pathways activated by both bacterial exotoxins and endotoxins...
  54. ncbi An integrated data analysis approach to characterize genes highly expressed in hepatocellular carcinoma
    Mohini A Patil
    Department of Biopharmaceutical Sciences, University of California, San Francisco, CA 94143, USA
    Oncogene 24:3737-47. 2005
    ..This approach of integrating other biological information with gene expression in the analysis helps select aberrantly expressed genes in HCC that may be further studied for their diagnostic or therapeutic utility...
  55. ncbi [Accumulation of soil inorganic nitrogen in mono-harvesting farmlands in northeast China in late autumn]
    Xin Chen
    Key Laboratory of Terrestrial Ecological Process, Institute of Applied Ecology, Chinese Academy of Sciences, Shenyang
    Ying Yong Sheng Tai Xue Bao 15:1887-90. 2004
    ....
  56. ncbi Granulin-epithelin precursor overexpression promotes growth and invasion of hepatocellular carcinoma
    Siu Tim Cheung
    Centre for the Study of Liver Disease and Departments of Surgery and Pathology, The University of Hong Kong, Pokfulam, Hong Kong, China
    Clin Cancer Res 10:7629-36. 2004
    ..The aim of this study was to investigate the clinical significance of GEP expression and its potential as a therapeutic target in HCC...
  57. ncbi Yin zi huang, an injectable multicomponent chinese herbal medicine, is a potent inhibitor of T-cell activation
    Xin Chen
    Basic Research Program, SAIC Frederick, Inc, National Cancer Institute Frederick, Frederick, MD 21702 1201, USA
    J Altern Complement Med 10:519-26. 2004
    ..The effects of 10 ingredient components of YZH were also evaluated...
  58. pmc The novel marker, DOG1, is expressed ubiquitously in gastrointestinal stromal tumors irrespective of KIT or PDGFRA mutation status
    Robert B West
    Department of Pathology, Stanford University Medical Center, 300 Pasteur Drive, Stanford, CA 94305, USA
    Am J Pathol 165:107-13. 2004
    ..Reactivity for DOG1 may aid in the diagnosis of GISTs, including PDGFRA mutants that fail to express KIT antigen, and lead to appropriate treatment with imatinib mesylate, an inhibitor of the KIT tyrosine kinase...
  59. ncbi Novel endothelial cell markers in hepatocellular carcinoma
    Xin Chen
    Department of Biopharmaceutical Sciences, University of California San Francisco, USA
    Mod Pathol 17:1198-210. 2004
    ..Our results underscore fundamental differences not only between neoplastic vs non-neoplastic liver cells but also between the hepatic sinusoidal endothelium of hepatocellular carcinoma and normal liver...
  60. ncbi Differential response of murine CD4+CD25+ and CD4+CD25- T cells to dexamethasone-induced cell death
    Xin Chen
    Basic Research Program, SAIC Frederick, Inc, Frederick, MD, USA
    Eur J Immunol 34:859-69. 2004
    ..Our data also suggest that selective protection of CD4+CD25+ T cell from apoptosis may constitute a role in immune tolerance for IL-2...
  61. ncbi A P element transformation vector for high levels of gene expression in germ-line cells of the ovary and undifferentiated cells in the developing eye of Drosophila
    Xin Chen
    Section of Molecular Cell and Developmental Biology, The Institute for Cellular and Molecular Biology, Austin, Texas 78712, USA
    Plasmid 47:61-5. 2002
    ..In addition, in the eye, pFAF is unique in that it activates transcription specifically in undifferentiated cells...