Wei Qiang Chen

Summary

Country: China

Publications

  1. doi request reprint Protective effects of green tea polyphenols on cognitive impairments induced by psychological stress in rats
    Wei Qiang Chen
    Department of Nutrition, Institute of Health and Environmental Medicine, Tianjin 300050, China
    Behav Brain Res 202:71-6. 2009
  2. ncbi request reprint Effects of zinc on the induction of metallothionein isoforms in hippocampus in stress rats
    Wei Qiang Chen
    Department of Nutrition, Institute of Health and Environmental Medicine, Tianjin 300050, China
    Exp Biol Med (Maywood) 231:1564-8. 2006
  3. doi request reprint Effects of epigallocatechin-3-gallate on behavioral impairments induced by psychological stress in rats
    Wei Qiang Chen
    Department of Nutrition, Institute of Health and Environmental Medicine, Tianjin 300050, China
    Exp Biol Med (Maywood) 235:577-83. 2010
  4. ncbi request reprint [Effects of zinc on the expression of metallothionein isoforms in hippocampus of stressed rats]
    Wei Qiang Chen
    Institute of Health and Environmental Medicine, Academy of Military Medical Sciences, Tianjin 300050, China
    Wei Sheng Yan Jiu 34:201-4. 2005
  5. ncbi request reprint [Effects of psychological stress on performances in open-field test of rats and tyrosine's modulation]
    Wei Qiang Chen
    Institute of Health and Environmental Medicine, Tianjin, China
    Zhongguo Ying Yong Sheng Li Xue Za Zhi 25:125-8. 2009
  6. doi request reprint Selection and affinity maturation of human antibodies against rabies virus from a scFv gene library using ribosome display
    Xiao Ling Zhao
    Institute of Health and Environmental Medicine, Academy of Military Medical Sciences, Heping District, Tianjin 300050, China
    J Biotechnol 144:253-8. 2009
  7. ncbi request reprint [The impairment of homocysteine on neurons and the related mechanisms]
    Yue Hou
    Institution of Health and Environmental Medicine, Academy of Military Medical Sciences, Tianjin 300050, China
    Zhongguo Ying Yong Sheng Li Xue Za Zhi 23:293-7. 2007
  8. ncbi request reprint [Preparation of human antibodies to TNF-alpha using ribosome display technology]
    Xiao Ling Zhao
    Institute of Health and Enviramental Medicine, Academy of Military Medical Sceience, Tianjin, China
    Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 25:145-9. 2009
  9. doi request reprint Generation and characterization of human monoclonal antibodies to G5, a linear neutralization epitope on glycoprotein of rabies virus, by phage display technology
    Xiao Ling Zhao
    Institute of Health and Environmental Medicine, Academy of Military Medical Sciences, Tianjin, China
    Microbiol Immunol 52:89-93. 2008
  10. doi request reprint Crystal and solution structure, stability and post-translational modifications of collapsin response mediator protein 2
    Viivi Majava
    Department of Biochemistry, University of Oulu, Finland
    FEBS J 275:4583-96. 2008

Collaborators

  • Yan Hong
  • Xiao Ling Zhao
  • Jun Yin
  • Gert Lubec
  • Wei Fei Diao
  • Arnold Pollak
  • Harald Hoger
  • Julius Paul Pradeep John
  • Viivi Majava
  • Lieselotte Kirchner
  • Yue Hou
  • Xue Dong Wang
  • Monika Skalicky
  • Andrus Viidik
  • Leila Afjehi-Sadat
  • Petri Kursula
  • Noora L√∂ytynoja
  • Heinz Redl
  • Yan Hohg
  • Oliver Pintsov
  • Alexander Petter-Puchner
  • Dong Lan Wang
  • Yi Yong Cheng
  • Shu Tian Li
  • Jian Guo Tang
  • Ji chun Yang
  • Jian Liu

Detail Information

Publications21

  1. doi request reprint Protective effects of green tea polyphenols on cognitive impairments induced by psychological stress in rats
    Wei Qiang Chen
    Department of Nutrition, Institute of Health and Environmental Medicine, Tianjin 300050, China
    Behav Brain Res 202:71-6. 2009
    ..To our knowledge, this is the first report showing the improving effects of GTPs on cognitive dysfunctions induced by psychological stress...
  2. ncbi request reprint Effects of zinc on the induction of metallothionein isoforms in hippocampus in stress rats
    Wei Qiang Chen
    Department of Nutrition, Institute of Health and Environmental Medicine, Tianjin 300050, China
    Exp Biol Med (Maywood) 231:1564-8. 2006
    ..The impairment of stress on the body may be involved with the nutrition status of zinc, and zinc deficiency can lower the body's adaptability to stress...
  3. doi request reprint Effects of epigallocatechin-3-gallate on behavioral impairments induced by psychological stress in rats
    Wei Qiang Chen
    Department of Nutrition, Institute of Health and Environmental Medicine, Tianjin 300050, China
    Exp Biol Med (Maywood) 235:577-83. 2010
    ..The related mechanisms may be involved with the changes of catecholamines, 5-hydroxytryptamine, cytokines and expressions of metallothioneins...
  4. ncbi request reprint [Effects of zinc on the expression of metallothionein isoforms in hippocampus of stressed rats]
    Wei Qiang Chen
    Institute of Health and Environmental Medicine, Academy of Military Medical Sciences, Tianjin 300050, China
    Wei Sheng Yan Jiu 34:201-4. 2005
    ..This study was conducted to evaluate the effects of different doses of zinc on the expression of metallothionein isoforms in hippocampus of stressed rats...
  5. ncbi request reprint [Effects of psychological stress on performances in open-field test of rats and tyrosine's modulation]
    Wei Qiang Chen
    Institute of Health and Environmental Medicine, Tianjin, China
    Zhongguo Ying Yong Sheng Li Xue Za Zhi 25:125-8. 2009
    ..To explore the effects of different doses of tyrosine modulation on behavioral performances in open field test of psychological stress rats...
  6. doi request reprint Selection and affinity maturation of human antibodies against rabies virus from a scFv gene library using ribosome display
    Xiao Ling Zhao
    Institute of Health and Environmental Medicine, Academy of Military Medical Sciences, Heping District, Tianjin 300050, China
    J Biotechnol 144:253-8. 2009
    ..Ribosome display technology is a robust tool for rapid isolation of human antibody fragments, and has exceptional strength in affinity maturation and molecular evolution in vitro...
  7. ncbi request reprint [The impairment of homocysteine on neurons and the related mechanisms]
    Yue Hou
    Institution of Health and Environmental Medicine, Academy of Military Medical Sciences, Tianjin 300050, China
    Zhongguo Ying Yong Sheng Li Xue Za Zhi 23:293-7. 2007
    ..To observe the impairment of homocysteine (Hcy) on neurons in vitro and the related mechanisms...
  8. ncbi request reprint [Preparation of human antibodies to TNF-alpha using ribosome display technology]
    Xiao Ling Zhao
    Institute of Health and Enviramental Medicine, Academy of Military Medical Sceience, Tianjin, China
    Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 25:145-9. 2009
    ..To prepare distinct human McAbs to TNF-alpha with high neutralizing potency using ribosome display technology...
  9. doi request reprint Generation and characterization of human monoclonal antibodies to G5, a linear neutralization epitope on glycoprotein of rabies virus, by phage display technology
    Xiao Ling Zhao
    Institute of Health and Environmental Medicine, Academy of Military Medical Sciences, Tianjin, China
    Microbiol Immunol 52:89-93. 2008
    ..They have potential for inclusion in an antibodies combination aimed for use in rabies PEP...
  10. doi request reprint Crystal and solution structure, stability and post-translational modifications of collapsin response mediator protein 2
    Viivi Majava
    Department of Biochemistry, University of Oulu, Finland
    FEBS J 275:4583-96. 2008
    ..By a proteomic approach, we further identified a number of post-translational modifications in CRMP-2 from rat brain hippocampus and mapped them onto the crystal structure...
  11. doi request reprint Hippocampal metabolic proteins are modulated in voluntary and treadmill exercise rats
    Lieselotte Kirchner
    Department of Pediatrics and Adolescent Medicine, Medical University of Vienna, Waehringer Guertel 18, A 1090 Vienna, Austria
    Exp Neurol 212:145-51. 2008
    ....
  12. doi request reprint Modulation of the hippocampal protein machinery in voluntary and treadmill exercising rats
    Wei Qiang Chen
    Medical University of Vienna, Department of Pediatrics, Waehringer Guertel 18, A 1090 Vienna, Austria
    Biochim Biophys Acta 1784:555-62. 2008
    ..005 was considered as statistically significant thus respecting multiple testing. The biological meaning of changed protein levels in hippocampus under different conditions of exercise is not known but warrants further investigation...
  13. ncbi request reprint Fluctuations of hippocampal neuronal protein levels over the estrous cycle in the rat
    Wei Fei Diao
    Department of Pediatrics, Medical University of Vienna, Waehringer Guertel 18, A 1090 Vienna, Austria
    Neurochem Int 52:1002-11. 2008
    ....
  14. ncbi request reprint Hippocampal signaling cascades are modulated in voluntary and treadmill exercise rats
    Wei Qiang Chen
    Department of Pediatrics, Medical University of Vienna, Vienna, Austria
    Electrophoresis 28:4392-400. 2007
    ..These results form the basis for functional studies elucidating mechanisms and links between exercise and hippocampal signaling and function...
  15. ncbi request reprint Mass spectrometric studies on mouse hippocampal synapsins Ia, IIa, and IIb and identification of a novel phosphorylation site at serine-546
    Julius Paul Pradeep John
    Department of Pediatrics, Medical University of Vienna, Waehringer Guertel 18, 1090 Vienna, Austria
    J Proteome Res 6:2695-710. 2007
    ..Several serine phosphorylation sites were confirmed, and a novel phosphorylation site was observed at Ser-546 in synapsin IIa in all gels analyzed...
  16. ncbi request reprint Hippocampal signaling protein levels are different in early and late metestrus in the rat
    Wei Fei Diao
    Department of Pediatrics, Medical University of Vienna, Waehringer Guertel 18, A 1090, Vienna, Austria
    Biochim Biophys Acta 1774:1044-51. 2007
    ..Moreover, signaling differences in hippocampus are challenging cognitive studies during these two metestrus phases probably revealing cognitive differences between early and late metestrus...
  17. ncbi request reprint Estrous-cycle-dependent hippocampal levels of signaling proteins
    Wei Fei Diao
    Department of Pediatrics, Medical University of Vienna, Waehringer Guertel 18, A 1090, Vienna, Austria
    Hippocampus 17:563-76. 2007
    ..Results from this study, although increasing complexity of protein knowledge, may help to design further investigations at the protein level and may assist to interpret literature on protein expression and brain protein levels...
  18. ncbi request reprint Protein profiling by the combination of two independent mass spectrometry techniques
    Wei Qiang Chen
    Department of Pediatrics, Medical University of Vienna, Waehringer Guertel 18, A 1090, Vienna, Austria
    Nat Protoc 1:1446-52. 2006
    ..Protein samples not identified by MALDI-MS or MS/MS (77% of all spots) are finally unambiguously identified by nano-LC-MS/MS (total identification rate 94%). This protocol can be completed in 6 weeks...
  19. ncbi request reprint Nitric oxide and oxygen radical attack on GDP-dissociation inhibitor 2 (GDI-2) in spinal cord injury of the rat
    Julius Paul Pradeep John
    Department of Pediatrics, Medical University of Vienna, Vienna, Austria
    J Proteome Res 6:1500-9. 2007
    ..On the basis of mass spectrometry evidence, we conclude that lipid-peroxidation and protein nitration do take place on an important signalling protein that may be prevented by specific experimental therapeutic interventions...
  20. ncbi request reprint Mice body weight gain is prevented after naked human leptin cDNA transfer into skeletal muscle by electroporation
    Xue Dong Wang
    National Laboratory of Protein Engineering and Plant Genetic Engineering, College of Life Sciences, Peking University, Beijing 100871, PR China
    J Gene Med 5:966-76. 2003
    ..In this investigation, the feasibility of gene therapy for obesity by electroporational transfer of naked plasmid with leptin cDNA into skeletal muscle was tested. Both young and adult mice were studied...
  21. ncbi request reprint [The regulation of metallothionein expression and its relationship to zinc]
    Wei Qiang Chen
    Sheng Li Ke Xue Jin Zhan 34:150-3. 2003