Wei Chen

Summary

Country: China

Publications

  1. doi Prediction of replication origins by calculating DNA structural properties
    Wei Chen
    Department of Physics, School of Sciences, Hebei United University, Tangshan, China
    FEBS Lett 586:934-8. 2012
  2. doi Identification of voltage-gated potassium channel subfamilies from sequence information using support vector machine
    Wei Chen
    Department of Physics, College of Sciences, Hebei United University, Tangshan 063000, China
    Comput Biol Med 42:504-7. 2012
  3. doi Prediction of ketoacyl synthase family using reduced amino acid alphabets
    Wei Chen
    Department of Physics, College of Sciences, Center for Genomics and Computational Biology, Hebei United University, Tangshan 063000, China
    J Ind Microbiol Biotechnol 39:579-84. 2012
  4. ncbi Recognition of DNase I hypersensitive sites in multiple cell lines
    Wei Chen
    Laboratory of Theoretical Biophysics, School of Physical Science and Technology, Inner Mongolia University, Hohhot 010021, China
    Int J Bioinform Res Appl 5:378-84. 2009
  5. doi Prediction of midbody, centrosome and kinetochore proteins based on gene ontology information
    Wei Chen
    Department of Physics, School of Basic Medical Sciences, North China Coal Medical University, Tangshan 063000, China
    Biochem Biophys Res Commun 401:382-4. 2010
  6. pmc iRSpot-PseDNC: identify recombination spots with pseudo dinucleotide composition
    Wei Chen
    Department of Physics, School of Sciences, Center for Genomics and Computational Biology, Hebei United University, Tangshan, China
    Nucleic Acids Res 41:e68. 2013
  7. pmc Identification of antioxidants from sequence information using naïve Bayes
    Peng Mian Feng
    School of Public Health, Hebei United University, Tangshan, China
    Comput Math Methods Med 2013:567529. 2013
  8. pmc Naïve Bayes classifier with feature selection to identify phage virion proteins
    Peng Mian Feng
    School of Public Health, Hebei United University, Tangshan 063000, China
    Comput Math Methods Med 2013:530696. 2013
  9. ncbi iNuc-PseKNC: a sequence-based predictor for predicting nucleosome positioning in genomes with pseudo k-tuple nucleotide composition
    Shou Hui Guo
    Key Laboratory for Neuro Information of Ministry of Education, Center of Bioinformatics, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu 610054, China, Gordon Life Science Institute, Belmont, Massachusetts, USA, Department of Physics, School of Sciences, Center for Genomics and Computational Biology, Hebei United University, Tangshan 063000, China and Center of Excellence in Genomic Medicine Research CEGMR, King Abdulaziz University, Jeddah, Saudi Arabia
    Bioinformatics 30:1522-9. 2014
  10. ncbi iSS-PseDNC: Identifying Splicing Sites Using Pseudo Dinucleotide Composition
    Wei Chen
    Department of Physics, School of Sciences, Center for Genomics and Computational Biology, Hebei United University, Tangshan 063000, China Gordon Life Science Institute, Boston, MA 02478, USA
    Biomed Res Int 2014:623149. 2014

Collaborators

Detail Information

Publications18

  1. doi Prediction of replication origins by calculating DNA structural properties
    Wei Chen
    Department of Physics, School of Sciences, Hebei United University, Tangshan, China
    FEBS Lett 586:934-8. 2012
    ..The predictive performance of the jackknife cross-validation indicates that DNA bendability and cleavage intensity have the ability to describe core replication regions and our model is effective in ORI prediction...
  2. doi Identification of voltage-gated potassium channel subfamilies from sequence information using support vector machine
    Wei Chen
    Department of Physics, College of Sciences, Hebei United University, Tangshan 063000, China
    Comput Biol Med 42:504-7. 2012
    ..These results indicate that VKCPred can be efficiently used to identify and annotate voltage-gated K(+) channels' subfamilies. The VKCPred software and dataset are freely available at http://cobi.uestc.edu.cn/people/hlin/tools/VKCPred/...
  3. doi Prediction of ketoacyl synthase family using reduced amino acid alphabets
    Wei Chen
    Department of Physics, College of Sciences, Center for Genomics and Computational Biology, Hebei United University, Tangshan 063000, China
    J Ind Microbiol Biotechnol 39:579-84. 2012
    ....
  4. ncbi Recognition of DNase I hypersensitive sites in multiple cell lines
    Wei Chen
    Laboratory of Theoretical Biophysics, School of Physical Science and Technology, Inner Mongolia University, Hohhot 010021, China
    Int J Bioinform Res Appl 5:378-84. 2009
    ..52%, 96.50%, 99.25% and 97.58%, respectively, and the mean areas under ROC curves (auROC) are all greater than 0.90. The prediction results indicate that the IDQD method is an effective tool for DHSs recognition...
  5. doi Prediction of midbody, centrosome and kinetochore proteins based on gene ontology information
    Wei Chen
    Department of Physics, School of Basic Medical Sciences, North China Coal Medical University, Tangshan 063000, China
    Biochem Biophys Res Commun 401:382-4. 2010
    ..The prediction model and dataset used in this article can be freely downloaded from http://cobi.uestc.edu.cn/people/hlin/tools/MicekiPred/...
  6. pmc iRSpot-PseDNC: identify recombination spots with pseudo dinucleotide composition
    Wei Chen
    Department of Physics, School of Sciences, Center for Genomics and Computational Biology, Hebei United University, Tangshan, China
    Nucleic Acids Res 41:e68. 2013
    ..As a user-friendly web-server, iRSpot-PseDNC is freely accessible at http://lin.uestc.edu.cn/server/iRSpot-PseDNC...
  7. pmc Identification of antioxidants from sequence information using naïve Bayes
    Peng Mian Feng
    School of Public Health, Hebei United University, Tangshan, China
    Comput Math Methods Med 2013:567529. 2013
    ..These results suggest that the proposed method could be an effective and promising high-throughput method for antioxidant protein identification. ..
  8. pmc Naïve Bayes classifier with feature selection to identify phage virion proteins
    Peng Mian Feng
    School of Public Health, Hebei United University, Tangshan 063000, China
    Comput Math Methods Med 2013:530696. 2013
    ..These results indicate that the proposed method could be as an effective and promising high-throughput method in phage proteomics research...
  9. ncbi iNuc-PseKNC: a sequence-based predictor for predicting nucleosome positioning in genomes with pseudo k-tuple nucleotide composition
    Shou Hui Guo
    Key Laboratory for Neuro Information of Ministry of Education, Center of Bioinformatics, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu 610054, China, Gordon Life Science Institute, Belmont, Massachusetts, USA, Department of Physics, School of Sciences, Center for Genomics and Computational Biology, Hebei United University, Tangshan 063000, China and Center of Excellence in Genomic Medicine Research CEGMR, King Abdulaziz University, Jeddah, Saudi Arabia
    Bioinformatics 30:1522-9. 2014
    ..Although some computational methods were proposed, most of them were species specific and neglected the intrinsic local structural properties that might play important roles in determining the nucleosome positioning on a DNA sequence...
  10. ncbi iSS-PseDNC: Identifying Splicing Sites Using Pseudo Dinucleotide Composition
    Wei Chen
    Department of Physics, School of Sciences, Center for Genomics and Computational Biology, Hebei United University, Tangshan 063000, China Gordon Life Science Institute, Boston, MA 02478, USA
    Biomed Res Int 2014:623149. 2014
    ....
  11. doi iHSP-PseRAAAC: Identifying the heat shock protein families using pseudo reduced amino acid alphabet composition
    Peng Mian Feng
    School of Public Health, Hebei United University, Tangshan 063000, China
    Anal Biochem 442:118-25. 2013
    ..As a user-friendly web server, iHSP-PseRAAAC is accessible to the public at http://lin.uestc.edu.cn/server/iHSP-PseRAAAC...
  12. pmc The organization of nucleosomes around splice sites
    Wei Chen
    Laboratory of Theoretical Biophysics, School of Physical Science and Technology, Inner Mongolia University, Hohhot 010021, China
    Nucleic Acids Res 38:2788-98. 2010
    ....
  13. ncbi Predicting peroxidase subcellular location by hybridizing different descriptors of Chou' pseudo amino acid patterns
    Yong Chun Zuo
    The Key Laboratory of Mammalian Reproductive Biology and Biotechnology of the Ministry of Education, Inner Mongolia University, Hohhot 010021, China Electronic address
    Anal Biochem 458:14-9. 2014
    ..0% in a jackknife test using a PSSM profile of pattern with width=5. We also demonstrate that the present GO annotation is far from complete or deep enough for annotating proteins with a specific function. ..
  14. ncbi PseKNC: a flexible web server for generating pseudo K-tuple nucleotide composition
    Wei Chen
    School of Sciences, and Center for Genomics and Computational Biology, Hebei United University, Tangshan 063000, China Gordon Life Science Institute, Belmont, MA 02478, USA Electronic address
    Anal Biochem 456:53-60. 2014
    ..It is anticipated that the PseKNC web server will become a very useful tool in computational genomics and genome sequence analysis...
  15. ncbi Predicting the types of J-proteins using clustered amino acids
    Pengmian Feng
    School of Public Health, Hebei United University, Tangshan 063000, China
    Biomed Res Int 2014:935719. 2014
    ..To enhance the value of the practical applications of the proposed model, an online web server was developed and can be freely accessed. ..
  16. doi A similarity distance of diversity measure for discriminating mesophilic and thermophilic proteins
    Yong Chun Zuo
    School of Physical Science and Technology, Inner Mongolia University, Hohhot 010021, China
    Amino Acids 44:573-80. 2013
    ..The prediction model and dataset used in this article can be freely downloaded from http://wlxy.imu.edu.cn/college/biostation/fuwu/KNN-ID/index.htm ...
  17. pmc iNuc-PhysChem: a sequence-based predictor for identifying nucleosomes via physicochemical properties
    Wei Chen
    Department of Physics, School of Sciences, Center for Genomics and Computational Biology, Hebei United University, Tangshan, China
    PLoS ONE 7:e47843. 2012
    ..It is anticipated that iNuc-PhysChem may become a useful high throughput tool for both basic research and drug design...
  18. doi Classification of antimicrobial peptide using diversity measure with quadratic discriminant analysis
    Wei Chen
    Laboratory of Theoretical Biophysics, School of Physical Science and Technology, Inner Mongolia University, Hohhot, 010021, China
    J Microbiol Methods 78:94-6. 2009
    ..In this work, an excellent algorithm of Increment of Diversity with Quadratic Discriminant analysis (IDQD) was proposed to classify antimicrobial peptides with diverse biological activities...