Research Topics
| Wei ChenSummaryCountry: China Publications
| Collaborators |
Detail Information
Publications
Prediction of replication origins by calculating DNA structural propertiesWei Chen
Department of Physics, School of Sciences, Hebei United University, Tangshan, China
FEBS Lett 586:934-8. 2012..The predictive performance of the jackknife cross-validation indicates that DNA bendability and cleavage intensity have the ability to describe core replication regions and our model is effective in ORI prediction...
Identification of voltage-gated potassium channel subfamilies from sequence information using support vector machineWei Chen
Department of Physics, College of Sciences, Hebei United University, Tangshan 063000, China
Comput Biol Med 42:504-7. 2012..These results indicate that VKCPred can be efficiently used to identify and annotate voltage-gated K(+) channels' subfamilies. The VKCPred software and dataset are freely available at http://cobi.uestc.edu.cn/people/hlin/tools/VKCPred/...
Prediction of ketoacyl synthase family using reduced amino acid alphabetsWei Chen
Department of Physics, College of Sciences, Center for Genomics and Computational Biology, Hebei United University, Tangshan 063000, China
J Ind Microbiol Biotechnol 39:579-84. 2012....
Recognition of DNase I hypersensitive sites in multiple cell linesWei Chen
Laboratory of Theoretical Biophysics, School of Physical Science and Technology, Inner Mongolia University, Hohhot 010021, China
Int J Bioinform Res Appl 5:378-84. 2009..52%, 96.50%, 99.25% and 97.58%, respectively, and the mean areas under ROC curves (auROC) are all greater than 0.90. The prediction results indicate that the IDQD method is an effective tool for DHSs recognition...
Prediction of midbody, centrosome and kinetochore proteins based on gene ontology informationWei Chen
Department of Physics, School of Basic Medical Sciences, North China Coal Medical University, Tangshan 063000, China
Biochem Biophys Res Commun 401:382-4. 2010..The prediction model and dataset used in this article can be freely downloaded from http://cobi.uestc.edu.cn/people/hlin/tools/MicekiPred/...
The organization of nucleosomes around splice sitesWei Chen
Laboratory of Theoretical Biophysics, School of Physical Science and Technology, Inner Mongolia University, Hohhot 010021, China
Nucleic Acids Res 38:2788-98. 2010....
iNuc-PhysChem: a sequence-based predictor for identifying nucleosomes via physicochemical propertiesWei Chen
Department of Physics, School of Sciences, Center for Genomics and Computational Biology, Hebei United University, Tangshan, China
PLoS ONE 7:e47843. 2012..It is anticipated that iNuc-PhysChem may become a useful high throughput tool for both basic research and drug design...
Classification of antimicrobial peptide using diversity measure with quadratic discriminant analysisWei Chen
Laboratory of Theoretical Biophysics, School of Physical Science and Technology, Inner Mongolia University, Hohhot, 010021, China
J Microbiol Methods 78:94-6. 2009..In this work, an excellent algorithm of Increment of Diversity with Quadratic Discriminant analysis (IDQD) was proposed to classify antimicrobial peptides with diverse biological activities...
