Research Topics
Genomes and Genes | Nan ChenSummaryCountry: China Publications
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Publications
[Chronic renal disease and dialysis in China]Nan Chen
Département de néphrologie de l hôpital Ruijin
Bull Acad Natl Med 196:977-81. 2012..In year 2010, the national dialysis registry, included 310 000 patients; 11 000 of them were living in Shanghai mean age 56 years M/F sex ratio 1.82. A governement program is underway to prevent and to detect CKD in China...
[The efficacy and safety of continuous erythropoietin receptor activator in dialytic patients with chronic renal anemia: an open, randomized, controlled, multi-center trial]Nan Chen
Renal Division, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200025, China Email
Zhonghua Nei Ke Za Zhi 51:502-7. 2012..E.R.A.) once every 4 weeks by subcutaneous administration on hemoglobin (Hb) maintenance in dialytic patients with chronic renal anemia who had been treated with stable dose of erythropoietin (EPO)...
Analysis of early kidney damage in hospitalized patients with chronic kidney disease: a multicenter studyNan Chen
Department of Nephrology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, PR China
Ren Fail 34:329-33. 2012..To identify the risk factors for early kidney damage in hospitalized Chinese patients with chronic kidney disease (CKD)...
Two brothers in one Chinese family with collagen type III glomerulopathyNan Chen
Department of Nephrology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China
Am J Kidney Dis 50:1037-42. 2007
Challenging chronic kidney disease: experience from chronic kidney disease prevention programs in Shanghai, Japan, Taiwan and AustraliaNan Chen
Department of Nephrology, Ruijin Hospital Affiliated to Shanghai Jiaotong University, School of Medicine, Shanghai, China
Nephrology (Carlton) 15:31-6. 2010..Furthermore, opportunistic screening with emphasis on early detection was effective in CKD prevention. The studies from those regions share experiences on early prevention and management of CKD...
Community-based study on CKD subjects and the associated risk factorsNan Chen
Department of Nephrology, Ruijin Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai 200025, People s Republic of China
Nephrol Dial Transplant 24:2117-23. 2009..The study was performed to investigate the prevalence, awareness and the risk factors of chronic kidney disease (CKD) in the community population in Shanghai, China...
Effects of DC-SIGN expression on renal tubulointerstitial fibrosis in nephritisTong Zhou
Department of Nephrology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, 197 Rui Jin Er Road, Shanghai 200025, China
Front Biosci 14:2935-43. 2009..These results suggest that DC-SIGN plays an important role in DC-mediated renal tubular interstitial lesions induced by immuno-inflammatory responses...
Propylthiouracil-induced antineutrophil cytoplasmic antibody (ANCA)-associated renal vasculitis versus primary ANCA-associated renal vasculitis: a comparative studyYong Xi Chen
Department of Nephrology, Ruijin Hospital Affiliated to Shanghai Jiaotong University, School of Medicine, Shanghai 200025, PR China
J Rheumatol 39:558-63. 2012..We analyzed the characteristics of patients with PTU-induced AAV with renal involvement and investigated the differences of the 2 diseases...
Effects of DC-SIGN expression on renal tubulointerstitial fibrosis in nephritisTong Zhou
Department of Nephrology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, 197 Rui Jin Er Road, Shanghai 200025, China
Front Biosci 14:3814-24. 2009..These results suggest that DC-SIGN plays an important role in DC-mediated renal tubular interstitial lesions induced by immuno-inflammatory responses...
Application of RIFLE criteria in Chinese patients with ANCA-associated renal vasculitisYong Xi Chen
Department of Nephrology, Shanghai Jiaotong University, School of Medicine, Shanghai, People s Republic of China
Clin Exp Rheumatol 29:951-7. 2011..Acute kidney injury (AKI) is common in patients with AASV but the value of RIFLE criteria is still unclear in those patients...
Analyzing fatal cases of Chinese patients with primary antineutrophil cytoplasmic antibodies-associated renal vasculitis: a 10-year retrospective studyYong Xi Chen
Department of Nephrology, Shanghai Ruijin Hospital affiliated to Shanghai Jiaotong University, School of Medicine, Shanghai, PR China
Kidney Blood Press Res 31:343-9. 2008..Few studies have been published focusing on AASV patients with poor prognosis...
Twenty-one novel mutations identified in the COL4A5 gene in Chinese patients with X-linked Alport's syndrome confirmed by skin biopsyJun Ma
Department of Nephrology, Shanghai Jiaotong University School of Medicine, Shanghai, China
Nephrol Dial Transplant 26:4003-10. 2011..Different mutations in the COL4A5 gene have been reported widely, but only a few mutations were identified in Chinese patients...
Mycophenolate mofetil or tacrolimus compared with intravenous cyclophosphamide in the induction treatment for active lupus nephritisXiao Li
Department of Nephrology, Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
Nephrol Dial Transplant 27:1467-72. 2012..The objective of this study is to assess the efficacy and safety of mycophenolate mofetil (MMF) and tacrolimus compared with intravenous cyclophosphamide (IVC) as induction therapies for active lupus nephritis (ALN)...
Identification of five novel variants in the thiazide-sensitive NaCl co-transporter gene in Chinese patients with Gitelman syndromeLing Qin
Department of Nephrology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, China
Nephrology (Carlton) 14:52-8. 2009..GS is caused by inactivating variants in the SLC12A3 gene, which encodes the thiazide-sensitive NaCl co-transporter. So far, more than 100 variants have been described in the SLC12A3 gene in Gitelman syndrome...
[The association of single nucleotide P-selectin gene polymorphism with IgA nephropathy]Zhao Hui Wang
Department of Nephrology, Ruijin Hospital, Shanghai Jiaotong University, Shanghai 200025, China
Zhonghua Nei Ke Za Zhi 45:559-64. 2006..P-selectin plays an important role in the pathogenesis and development of IgA nephropathy. The purpose of this study is to find a possible relationship between P-selectin gene polymorphism and IgA nephropathy...
Identification and functional analysis of a novel TRPC6 mutation associated with late onset familial focal segmental glomerulosclerosis in Chinese patientsBin Zhu
Department of Nephrology, Ruijin Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 200025, China
Mutat Res 664:84-90. 2009..However, the role of TRPC6 variation in Chinese patients with late onset familial FSGS remains unclear. Here, we screened 31 Chinese pedigrees with late onset familial FSGS for changes in TRPC6 by DNA sequence analysis...
Predicting progression of IgA nephropathy: new clinical progression risk scoreJingyuan Xie
Nephrology Department, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
PLoS ONE 7:e38904. 2012..The new progression risk score calculated based on these four baseline variables offers a simple clinical tool for risk stratification...
Identification of a novel WNK4 mutation in Chinese patients with pseudohypoaldosteronism type IIChong Zhang
Department of Nephrology, School of Medicine, Shanghai Jiao Tong University, China
Nephron Physiol 118:p53-61. 2011..In this report, we screened 4 Chinese PHA2 pedigrees for WNK4 mutations, identified a novel mutation, and studied its effects on NCC protein trafficking in vitro...
Analysis of cardiovascular disease in Chinese inpatients with chronic kidney diseaseXiao Nong Chen
Department of Nephrology, Ruijin Hospital Affiliated to Shanghai Jiaotong University, School of Medicine, PR China
Intern Med 50:1797-801. 2011..To investigate the prevalence of cardiovascular disease (CVD) in a Chinese patient population with different stages of chronic kidney disease (CKD)...
Analyzing Chinese patients with post-operative acute kidney injuryWen Zhang
Department of Nephrology, Shanghai Ruijin Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, PR China
Ren Fail 33:795-800. 2011..To investigate clinical characteristics and risk factors of Chinese patients with post-operative acute kidney injury (PO-AKI)...
Analysis of factors associated with renal function in Chinese adults with congenital solitary kidneyYingyu Wang
Department of Nephrology, Ruijin Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, PR China
Intern Med 49:2203-9. 2010..The purpose of this study was to identify factors that are independently associated with renal function progression in patients with congenital solitary kidney...
Renal involvement and followup of 130 patients with primary Sjögren's syndromeHon Ren
Department of Nephrology, Ruijin Hospital Affiliated to Shanghai Jiaotong University, School of Medicine, Shanghai, PR China
J Rheumatol 35:278-84. 2008..To identify the clinical characteristics, pathological changes, and outcome of patients with primary Sjögren's syndrome (pSS)...
Clinicopathological characteristics and outcome of Chinese patients with thrombotic thrombocytopenic purpura-hemolytic uremic syndrome: a 9-year retrospective studyWen Zhang
Department of Nephrology, Shanghai Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, PR China
Nephron Clin Pract 112:c177-83. 2009..Few studies have been published focusing on Chinese patients with TTP-HUS. We performed a retrospective study on the clinical characteristics and outcome of Chinese patients with TTP-HUS...
ACTN4 gene mutations and single nucleotide polymorphisms in idiopathic focal segmental glomerulosclerosisShengchuan Dai
Department of Nephrology, Ruijin Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, China
Nephron Clin Pract 111:c87-94. 2009..To investigate the association between mutations or single nucleotide polymorphisms (SNPs) of the gene ACTN4 in Chinese patients with idiopathic focal segmental glomerulosclerosis (FSGS)...
Abnormal glucose metabolism and insulin sensitivity in chinese patients with Gitelman syndromeHong Ren
Department of Nephrology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China
Am J Nephrol 37:152-7. 2013..Both hypokalemia and hypomagnesemia were reported to cause impaired glucose tolerance and/or insulin resistance, but it is unclear whether impaired glucose tolerance and/or insulin resistance are common in GS patients...
[Impact of therapeutic time on the prognosis in critically ill patients with acute renal failure who needed renal replacement therapy]Ming li Zhu
Shanghai Acute Renal Failure Work Group, Renji Hospital, Shanghai Jiaotong University, School of Medicine, Shanghai 200127, China
Zhongguo Wei Zhong Bing Ji Jiu Yi Xue 23:421-5. 2011..To investigate the impact of therapeutic time on the prognosis in critically ill patients with acute renal failure (ARF) who needed renal replacement therapy (RRT), and to analyze the risk factors of death...
Novel SLC12A3 mutations in Chinese patients with Gitelman's syndromeLeping Shao
Department of Nephrology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China
Nephron Physiol 108:p29-36. 2008..Inactivating mutations of the SLC12A3 gene are the most common cause of Gitelman's syndrome (GS), a disorder inherited as an autosomal recessive trait. In a minority of cases, GS-like phenotypes are caused by mutations in the CLCNKB gene...
[Analysis of drug-induced acute renal failure in Shanghai]Miao lin Che
Department of Nephrology, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200127, China
Zhonghua Yi Xue Za Zhi 89:744-9. 2009..To investigate the incidence and prognosis of drug-induced acute renal failure (ARF) in Shanghai...
Peritubular capillary loss is ameliorated by ramipril or valsartan treatmentBin Zhang
Department of Nephrology, Guangdong Provincial People s Hospital, Nanfang Medical University, Guangzhou, China
Microcirculation 15:337-48. 2008..To identify the preservation of peritubular capillaries conferred by ramipril or valsartan treatment as an additional mechanism for their renoprotection...
Protective effects of exogenous interleukin 18-binding protein in a rat model of acute renal ischemia-reperfusion injuryJun Wang
Department of Nephrology, Ruijin Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, People s Republic of China
Shock 37:333-40. 2012..Exogenous IL-18BP attenuated renal injury caused by I/R via inhibiting inflammation in the renal tissue and protecting tubular epithelium and PTC endothelium...
DC-SIGN modulates DC maturation and function in rat renal tubulointerstitial lesionsMinchao Cai
Department of Nephrology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, 197 Ruijin Er Road, Shanghai 200025, China
Front Biosci 17:1795-803. 2012..PsL-EGFmAb inhibited DC migration, maturation and function by targeting DC-SIGN, and may therefore be a potential treatment for NTN...
Chronic kidney disease is prevalent in Chinese patients admitted with verified cerebrovascular lesions and predicts short-term prognosisJing Xu
Department of Nephrology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
Nephrol Dial Transplant 26:2590-4. 2011..While the link between CKD and cardiovascular events is well established, the link with cerebrovascular lesions (CVL) has been less well described...
[Correlation between traditional Chinese medicine syndromes in primary immunoglobulin A nephropathy and A267G in 5'-untranslated region within exonal of megsin gene]Yi Fei Zhong
Department of Nephrology, Longhua Hospital, Shanghai University of Tradtional Chinese Medicine, Shanghai 200032, China
Zhong Xi Yi Jie He Xue Bao 6:463-7. 2008....
Coiled versus straight peritoneal dialysis catheters: a randomized controlled trial and meta-analysisJingyuan Xie
Department of Nephrology, Ruijin Hospital, Shanghai Jiaotong University, School of Medicine, Shanghai, China
Am J Kidney Dis 58:946-55. 2011..The relative benefits of these designs have not been studied adequately. The objective of this study is to compare the clinical outcomes of coiled- versus straight-end swan neck peritoneal dialysis catheters...
Phosphoproteomic study of human tubular epithelial cell in response to transforming growth factor-beta-1-induced epithelial-to-mesenchymal transitionYong Xi Chen
Department of Nephrology, Shanghai Ruijin Hospital affiliated to Shanghai Jiaotong University, School of Medicine, Shanghai, PR China
Am J Nephrol 31:24-35. 2010..We applied isobaric tags for relative and absolute quantification (iTRAQ) technology to profile the phosphoproteins in tubular epithelial cells in response to TGF-beta-induced EMT in order to further study molecular events...
Functional analysis of promoter mutations in the ACTN4 and SYNPO genes in focal segmental glomerulosclerosisShengchuan Dai
Department of Nephrology, Ruijin Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, China
Nephrol Dial Transplant 25:824-35. 2010..To investigate the promoter mutations of ACTN4 and SYNPO genes in patients with idiopathic focal segmental glomerulosclerosis (FSGS), and to provide functional analysis of these mutations in the role of FSGS occurrence...
PsL-EGFmAb inhibits the stimulatory functions of human dendritic cells via DC-SIGNTong Zhou
Department of Nephrology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, 197 Rui Jin Er Road, Shanghai 200025, China
Front Biosci 13:7269-76. 2008..Our present studies indicate that PsL-EGFmAb may be a useful reagent for regulating DC-SIGN expression and DC function...
Peroxisome proliferator-activated receptor-gamma (PPAR-gamma) agonists attenuate the profibrotic response induced by TGF-beta1 in renal interstitial fibroblastsWeiming Wang
Department of Nephrology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China
Mediators Inflamm 2007:62641. 2007..In order to elucidate the antifibrotic mechanism of PPAR-gamma agonists, we investigated the effects of PPAR-gamma activation on TGF-beta1-induced renal interstitial fibroblasts...
Effect of MDR1 gene polymorphism on progression of end-stage renal diseaseWei xia Zhang
Institute of Clinical Pharmacology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200025, China
Acta Pharmacol Sin 28:579-83. 2007....
PPAR-gamma agonists inhibit TGF-beta1-induced chemokine expression in human tubular epithelial cellsWei Ming Wang
Department of Nephrology, Ruijin Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai 200025, China
Acta Pharmacol Sin 30:107-12. 2009....
Tacrolimus versus cyclophosphamide in steroid-dependent or steroid-resistant focal segmental glomerulosclerosis: a randomized controlled trialHong Ren
Department of Nephrology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China
Am J Nephrol 37:84-90. 2013..The efficacy and safety of tacrolimus (TAC) and cyclophosphamide (CTX) were prospectively examined in steroid-dependent or steroid-resistant primary focal segmental glomerulosclerosis (FSGS)...
[Effects of peroxisome proliferators-activated receptor gamma agonists on transforming growth factor-beta1 and Smads signal pathway: experiment with rat renal fibroblasts]Wei-Ming Wang
Department of Nephrology, Ruijin Hospital, Shanghai Jiaotong University, Shanghai 200025, China
Zhonghua Yi Xue Za Zhi 86:740-4. 2006....
[Association of single nucleotide polymorphism of megsin gene with IgA nephropathy]Zhao Hui Wang
Department of Nephrology, Ruijin Hospital, Shanghai Jiaotong University School of Medical, Shanghai 200025, China
Zhonghua Yi Xue Za Zhi 86:1337-41. 2006..To investigate whether the single nucleotide polymorphisms (SNPs) in the gene of megsin, a novel serine protease inhibitor, account for the pathogenicity of IgA nephropathy (IgAN)...
Mycophenolate mofetil in induction and maintenance therapy of severe lupus nephritis: a meta-analysis of randomized controlled trialsBin Zhu
Department of Nephrology, Ruijin Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 200025, China
Nephrol Dial Transplant 22:1933-42. 2007..This meta-analysis of randomized controlled trials (RCTs) assesses the benefits and harms of MMF in the induction and maintenance therapy of severe LN...
High-frequency variant p.T60M in NaCl cotransporter and blood pressure variability in Han ChineseLeping Shao
Department of Nephrology, Affiliated Hospital of Qingdao University School of Medicine, Qingdao, PR China
Am J Nephrol 35:515-9. 2012..However, the association of heterozygous NCC mutation p.Thr60Met and BP has not yet been studied...
Improvement of awareness, treatment and control of hypertension among chronic kidney disease patients in China from 1999 to 2005Yu Wang
Renal Division, Department of Medicine, Peking University First Hospital, Institute of Nephrology, Peking University, Beijing, China
Hypertens Res 32:444-9. 2009..Improvement of awareness and general control of hypertension were demonstrated. Education of both physicians and patients regarding optimal BP control should be reinforced in the future...
Valsartan inhibited the accumulation of dendritic cells in rat fibrotic renal tissueKaiyin Wu
Department of Nephrology, Rui Jin Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai 200025, China
Cell Mol Immunol 3:213-20. 2006..The local DCs accumulation was related to tubulointerstitial fibrosis and renal dysfunction following renal ablation. Blockade to angiotensin II might be a potent way to attenuate renal immuno-inflammatory injury...
Polyvalent DNA-graphene nanosheets "click" conjugatesZihao Wang
Laboratory of Physical Biology, Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai, 201800, China
Nanoscale 4:394-9. 2012..Therefore, this DNA-graphene conjugates could be explored as the assembly unit for advanced DNA nano-architectures in the field of DNA nanotechnology...
Propylthiouracil-associated antineutrophil cytoplasmic autoantibody-positive vasculitis: retrospective study of 19 casesYong Xi Chen
Department of Nephrology, Shanghai Ruijin Hospital affiliated to Shanghai Jiaotong University, School of Medicine, Shanghai, China
J Rheumatol 34:2451-6. 2007..To investigate the features, followup data, and outcomes of patients with propylthiouracil (PTU)-associated antineutrophil cytoplasmic autoantibody (ANCA)-positive vasculitis...
Peritoneal dialysis outflow failure from omental wrapping diagnosed by catheterographyJing Yuan Xie
Department of Nephrology, Ruijin Hospital, Shanghai Jiaotong University, School of Medicine, Shanghai, Peoples Republic of China
Am J Kidney Dis 56:1006-11. 2010..The catheter was stripped from the omentum and repositioned in the Douglas peritoneal sac. Catheterography is a reliable, safe, noninvasive, and inexpensive alternative procedure to diagnose outflow failure caused by omental wrapping...
Analysis of the gene expression profile of curcumin-treated kidney on endotoxin-induced renal inflammationFang Zhong
Department of Nephrology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, People s Republic of China
Inflammation 36:80-93. 2013..The kidney gene expression profile in the inflammatory state was clarified by using gene chip technology. Furthermore, we confirmed that curcumin treatment can change the gene expression profile...
Detection of COL4A5 gene mutations in Chinese patients with Alport's syndromeXiaoxia Pan
Department of Nephrology, Ruijin Hospital, Shanghai Second Medical University, Shanghai 200025, People s Republic of China
Nephrol Dial Transplant 19:1123-8. 2004....
1H NMR spectroscopy analysis of metabolites in the kidneys provides new insight into pathophysiological mechanisms: applications for treatment with Cordyceps sinensisFang Zhong
Department of Nephrology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
Nephrol Dial Transplant 27:556-65. 2012..The number of patients with chronic kidney disease (CKD) is continuously growing worldwide. Treatment with traditional Chinese medicine might slow the progression of CKD...
Post liver transplantation acute kidney injury in a rat model of syngeneic orthotopic liver transplantationJun Wang
Department of Nephrology, Ruijin Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, PR China
Lab Invest 91:1158-69. 2011..Our results demonstrate that protection of the liver graft and inhibition of the systemic inflammatory response are vital in reducing the risk of post-LT AKI...
A new locus for hereditary hypotrichosis simplex maps to chromosome 13q12.12 approximately 12.3 in a Chinese familyChao Xu
State Key Laboratory of Medical Genomics, Center of Molecular Medicine, Ruijin Hospital, An Affiliate of Shanghai JiaoTong University Medical School, Shanghai, China
J Cutan Pathol 37:758-63. 2010..Hereditary hypotrichosis simplex (MIM 146520, HHS) is a rare form of nonsyndromic alopecia. The locus for autosomal dominant HHS was mapped to 18p11.32-p11.23 and 6p21.3, respectively, suggestive of genetic heterogeneity...
Angiotensin II-mediated activation of fibrotic pathways through ERK1/2 in rat peritoneal mesothelial cellsJing Yuan Xie
Department of Nephrology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, PR China
Ren Fail 32:871-9. 2010....
Mineral and bone disorder in Chinese dialysis patients: a multicenter studyXianglei Kong
Renal Division, Department of Medicine, Peking University First Hospital, Peking University Institute of Nephrology, Key Laboratory of Renal Disease, Ministry of Health of China, Key Laboratory of Chronic Kidney Disease Prevention and Treatment Peking University, Ministry of Education, Beijing, China
BMC Nephrol 13:116. 2012..Studies regarding the status of MBD treatment in developing countries, especially in Chinese dialysis patients are extremely limited...
[Clinical features of polymyositis and dermatomyositis in four patients with renal involvement as mainly presentation.]Ying Qian
Department of Nephrology, Shanghai Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200025, China
Zhonghua Nei Ke Za Zhi 48:930-2. 2009..To investigate the clinical features of polymyositis (PM) and dermatomyositis (DM) with renal involvement as mainly presentation...
The pheV phenylalanine tRNA gene Klebsiella pneumoniae clinical isolates is an integration hotspot for possible niche-adaptation genomic islandsNan Chen
Department of Laboratory Medicine, Huashan Hospital, Shanghai Medical College, Fudan University, 12 Central Urumqi Road, Shanghai, 200040, People s Republic of China
Curr Microbiol 60:210-6. 2010..We propose that the pheV-associated islands described in this study may contribute to fine tuning and adaptation of K. pneumoniae strains toward preferred infection and/or colonization pathways...
Serum proteome alteration of severe sepsis in the treatment of continuous renal replacement therapyYu Gong
Department of Nephrology, Affiliated Renmin Hospital, School of Medical Science and Laboratory Medicine, Jiangsu University, Zhenjiang, China
Nephrol Dial Transplant 24:3108-14. 2009..The aim of this research was to study the serum proteome alterations of severe sepsis patients in the treatment of CRRT. Improved knowledge of proteome alteration could lead to the development of more efficient treatment strategies...
Clinical experience with nadroparin in patients undergoing dialysis for renal impairmentWen Zhang
Department of Nephrology, Ruijin Hospital Affiliated to Shanghai Jiaotong University, School of Medicine, Shanghai, China
Hemodial Int 15:379-94. 2011..Nadroparin administered by a bolus dose, followed by a continuous infusion was also shown to be effective and safe in patients undergoing continuous renal replacement therapy for acute renal failure...
[Transfection of recombinant bone morphogenetic protein-7 expressing plasmid into cultured human renal tubular epithelial cells attenuates the extracellular matrix accumulation induced by transforming growth factor-beta]Ya Li
Department of Nephrology, Ruijin Hospital, Shanghai Second Medical University, Shanghai 200025, China
Zhonghua Yi Xue Za Zhi 86:544-8. 2006..BMP-7 exerts its antifibrotic effect partially through blocking the TGF-beta-induced accumulation of extracellular matrix in human renal tubular epithelial cells...
[The analysis of the factors for postoperative blood pressure recovery of aldosterone producing adenoma patients]Ding-yi Liu
Department of Urology, Ruijin Hospital, Shanghai Second Medical University, Shanghai 200025, China
Zhonghua Wai Ke Za Zhi 42:587-9. 2004..CONCLUSION: The renal pathological changes and increased resistance of retinal blood vessel are the main reasons leading to postoperative hypertension in patients with APA...
The cytotoxicity of cadmium-based quantum dotsNan Chen
Laboratory of Physical Biology, Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai, China
Biomaterials 33:1238-44. 2012....
