Jing Chen

Summary

Country: China

Publications

  1. ncbi [Mutation screening of MITF gene in patients with Waardenburg syndrome type 2]
    Jing Chen
    Institute of Otolaryngology, Chinese PLA General Hospital, Beijing 100853, China E mail
    Yi Chuan 30:433-8. 2008
  2. pmc Functional mutation of SMAC/DIABLO, encoding a mitochondrial proapoptotic protein, causes human progressive hearing loss DFNA64
    Jing Cheng
    Institute of Otolaryngology, Chinese PLA General Hospital, Beijing, China
    Am J Hum Genet 89:56-66. 2011
  3. ncbi Coexistence of mitochondrial 12S rRNA C1494T and CO1/tRNA(Ser(UCN)) G7444A mutations in two Han Chinese pedigrees with aminoglycoside-induced and non-syndromic hearing loss
    Huijun Yuan
    Institute of Otolaryngology, Chinese PLA General Hospital, Beijing, China
    Biochem Biophys Res Commun 362:94-100. 2007
  4. ncbi [Clinical and genetic analysis of a patient with Treacher Collins syndrome in TCOF1 gene]
    Hongbo Li
    Department of Otolaryngology Head and Neck Surgery, Chinese PLA General Hospital, Institute of Otolaryngology, Beijing, 223301, China
    Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 26:459-62. 2012
  5. ncbi Variants in mitochondrial tRNAGlu, tRNAArg, and tRNAThr may influence the phenotypic manifestation of deafness-associated 12S rRNA A1555G mutation in three Han Chinese families with hearing loss
    Wie yen Young
    Institute of Otolaryngology, Chinese PLA General Hospital, Beijing, China
    Am J Med Genet A 140:2188-97. 2006
  6. doi Novel missense mutations in MYO7A underlying postlingual high- or low-frequency non-syndromic hearing impairment in two large families from China
    Yi Sun
    Department of Otolaryngology, Head and Neck Surgery, Institute of Otolaryngology, Chinese PLA General Hospital, Beijing, China
    J Hum Genet 56:64-70. 2011
  7. ncbi Inhibition of plasminogen activator inhibitor type-1 expression in HepG2 cells by fenofibrate may be associated with Smad signaling
    Jing Chen
    Department of Geriatric Cardiology, Chinese PLA General Hospital, Beijing 100853, China
    Clin Chim Acta 387:18-23. 2008

Collaborators

Detail Information

Publications7

  1. ncbi [Mutation screening of MITF gene in patients with Waardenburg syndrome type 2]
    Jing Chen
    Institute of Otolaryngology, Chinese PLA General Hospital, Beijing 100853, China E mail
    Yi Chuan 30:433-8. 2008
    ....
  2. pmc Functional mutation of SMAC/DIABLO, encoding a mitochondrial proapoptotic protein, causes human progressive hearing loss DFNA64
    Jing Cheng
    Institute of Otolaryngology, Chinese PLA General Hospital, Beijing, China
    Am J Hum Genet 89:56-66. 2011
    ..Our work identifies DFNA64 as the human genetic disorder associated with SMAC/DIABLO malfunction and suggests that mutant SMAC/DIABLO(S71L) might cause mitochondrial dysfunction...
  3. ncbi Coexistence of mitochondrial 12S rRNA C1494T and CO1/tRNA(Ser(UCN)) G7444A mutations in two Han Chinese pedigrees with aminoglycoside-induced and non-syndromic hearing loss
    Huijun Yuan
    Institute of Otolaryngology, Chinese PLA General Hospital, Beijing, China
    Biochem Biophys Res Commun 362:94-100. 2007
    ..However, aminoglycosides and other nuclear modifier genes play a modifying role in the phenotypic manifestation of the C1494T mutation in these Chinese families...
  4. ncbi [Clinical and genetic analysis of a patient with Treacher Collins syndrome in TCOF1 gene]
    Hongbo Li
    Department of Otolaryngology Head and Neck Surgery, Chinese PLA General Hospital, Institute of Otolaryngology, Beijing, 223301, China
    Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 26:459-62. 2012
    ..To analyze the clinical and genetic features of a patient with Treacher Collins syndrome (TCS), and identify the mutation in TCOF1 gene...
  5. ncbi Variants in mitochondrial tRNAGlu, tRNAArg, and tRNAThr may influence the phenotypic manifestation of deafness-associated 12S rRNA A1555G mutation in three Han Chinese families with hearing loss
    Wie yen Young
    Institute of Otolaryngology, Chinese PLA General Hospital, Beijing, China
    Am J Med Genet A 140:2188-97. 2006
    ..Therefore, these mtDNA mutations may have a potential modifier role in increasing the penetrance and expressivity of the deafness-associated 12S rRNA A1555G mutation in those Chinese pedigrees...
  6. doi Novel missense mutations in MYO7A underlying postlingual high- or low-frequency non-syndromic hearing impairment in two large families from China
    Yi Sun
    Department of Otolaryngology, Head and Neck Surgery, Institute of Otolaryngology, Chinese PLA General Hospital, Beijing, China
    J Hum Genet 56:64-70. 2011
    ..We speculate that the low-frequency sensorineural hearing loss in this DFNA11 family was not associated with endolymphatic hydrops...
  7. ncbi Inhibition of plasminogen activator inhibitor type-1 expression in HepG2 cells by fenofibrate may be associated with Smad signaling
    Jing Chen
    Department of Geriatric Cardiology, Chinese PLA General Hospital, Beijing 100853, China
    Clin Chim Acta 387:18-23. 2008
    ..We investigated the molecular mechanism underlying the effect of fenofibrate on expression of plasminogen activator inhibitor type-1 (PAI-1) in HepG2 cells...