Guozhen Chen

Summary

Country: China

Publications

  1. pmc Spatiotemporal expression of histone acetyltransferases, p300 and CBP, in developing embryonic hearts
    Guozhen Chen
    Department of Cardiology, The Children s Hospital of Chongqing Medical University, Chongqing, PR China
    J Biomed Sci 16:24. 2009
  2. doi request reprint Ethanol and its metabolites induce histone lysine 9 acetylation and an alteration of the expression of heart development-related genes in cardiac progenitor cells
    Lilin Zhong
    Department of Cardiology, The Children s Hospital of Chongqing Medical University, 136 Zhong Shan Er Road, Yu Zhong District, 400014 Chongqing, People s Republic of China
    Cardiovasc Toxicol 10:268-74. 2010
  3. doi request reprint Inhibition of p300-HAT results in a reduced histone acetylation and down-regulation of gene expression in cardiac myocytes
    Huichao Sun
    Heart Centre, Children s Hospital of Chongqing Medical University, Chongqing, PR China
    Life Sci 87:707-14. 2010

Collaborators

  • Jing Zhu
  • Lilin Zhong
  • Huichao Sun
  • Jie Tian
  • Xuefang Yang
  • Xupei Huang
  • Tiewei Lv
  • Yuan Chen
  • Guoying Huang
  • Yasha Li

Detail Information

Publications3

  1. pmc Spatiotemporal expression of histone acetyltransferases, p300 and CBP, in developing embryonic hearts
    Guozhen Chen
    Department of Cardiology, The Children s Hospital of Chongqing Medical University, Chongqing, PR China
    J Biomed Sci 16:24. 2009
    ..The expression of p300 is earlier and more predominate, suggesting that p300 may play a more important role in embryonic heart development especially during cardiac precursor cell induction and interventricular septum formation...
  2. doi request reprint Ethanol and its metabolites induce histone lysine 9 acetylation and an alteration of the expression of heart development-related genes in cardiac progenitor cells
    Lilin Zhong
    Department of Cardiology, The Children s Hospital of Chongqing Medical University, 136 Zhong Shan Er Road, Yu Zhong District, 400014 Chongqing, People s Republic of China
    Cardiovasc Toxicol 10:268-74. 2010
    ..The altered histone H3 acetylation at lysine 9 has an important impact on the expression of the heart development-related genes, which may be one of the mechanisms underlying the alcohol-induced CHD...
  3. doi request reprint Inhibition of p300-HAT results in a reduced histone acetylation and down-regulation of gene expression in cardiac myocytes
    Huichao Sun
    Heart Centre, Children s Hospital of Chongqing Medical University, Chongqing, PR China
    Life Sci 87:707-14. 2010
    ..In this study, we investigated the relationship between histone hypo-acetylation and the expression of cardiac-specific genes to explore the underlying mechanisms...