Zhouhua Li


Affiliation: Capital Normal University
Country: China


  1. Li Z, Liu S, Cai Y. Differential Notch activity is required for homeostasis of malpighian tubules in adult Drosophila. J Genet Genomics. 2014;41:649-52 pubmed publisher
  2. Xu R, Li J, Zhao H, Kong R, Wei M, Shi L, et al. Self-restrained regulation of stem cell niche activity by niche components in the Drosophila testis. Dev Biol. 2018;439:42-51 pubmed publisher
    ..Our data demonstrate the critical roles of niche components (CySCs) in the self-restrained regulation of niche activity, which could be shed light on niche activity regulation in general. ..
  3. Huang X, Shi L, Cao J, He F, Li R, Zhang Y, et al. The sterile 20-like kinase tao controls tissue homeostasis by regulating the hippo pathway in Drosophila adult midgut. J Genet Genomics. 2014;41:429-38 pubmed publisher
    ..Together, our results provide insights into our understanding of the mechanisms of stem cell proliferation and tissue homeostasis control. ..
  4. Li Z, Liu S, Cai Y. EGFR/MAPK signaling regulates the proliferation of Drosophila renal and nephric stem cells. J Genet Genomics. 2015;42:9-20 pubmed publisher
    ..Together, our data suggest a principal role of EGFR/MAPK signaling in regulating RNSC proliferation, which may provide important clues for understanding mammalian kidney repair and regeneration following injury. ..
  5. Lu Y, Li Z. Notch signaling downstream target E(spl)mbeta is dispensable for adult midgut homeostasis in Drosophila. Gene. 2015;560:89-95 pubmed publisher
    ..Together, these data indicate that the proliferation and differentiation of ISCs are not regulated by individual Notch downstream target, but by different downstream targets collectively. ..
  6. Ma M, Zhao H, Zhao H, Binari R, Perrimon N, Li Z. Wildtype adult stem cells, unlike tumor cells, are resistant to cellular damages in Drosophila. Dev Biol. 2016;411:207-216 pubmed publisher
    ..Together, these data demonstrate that wildtype adult stem cells and tumor cells show dramatic differences in sensitivity to cellular damages, thus providing potential therapeutic implications targeting tumorigenesis. ..