Junfa Li

Summary

Affiliation: Capital University of Medical Sciences
Country: China

Publications

  1. pmc Protein kinases mediate increment of the phosphorylation of cyclic AMP-responsive element binding protein in spinal cord of rats following capsaicin injection
    Jing Wu
    Department of Neurology, University of Texas Health Science Center, Houston, TX 77030 1501, USA
    Mol Pain 1:26. 2005
  2. ncbi request reprint Increased phosphorylation of neurogranin in the brain of hypoxic preconditioned mice
    Junfa Li
    Institute for Biomedical Science of Pain, Beijing Key Laboratory for Neural Regeneration and Repairing, Department of Neurobiology, Capital University of Medical Sciences, Beijing 100054, China
    Neurosci Lett 391:150-3. 2006
  3. ncbi request reprint Identification of protein kinase C isoforms involved in cerebral hypoxic preconditioning of mice
    Junfa Li
    Institute for Biomedical Science of Pain, Beijing Key Laboratory for Neural Regeneration and Repairing, Department of Neurobiology, Capital University of Medical Sciences, Beijing 100054, China
    Brain Res 1060:62-72. 2005
  4. ncbi request reprint Increased isoform-specific membrane translocation of conventional and novel protein kinase C in human neuroblastoma SH-SY5Y cells following prolonged hypoxia
    Junfa Li
    Institute for Biomedical Science of Pain, Beijing Key Laboratory for Neural Regeneration and Repairing, Department of Neurobiology, Capital University of Medical Sciences, 10 You An Men Wai Xi Tou Tiao, Beijing 100054, China
    Brain Res 1093:25-32. 2006
  5. ncbi request reprint Decreased phosphorylation and protein expression of ERK1/2 in the brain of hypoxic preconditioned mice
    Caixia Long
    Institute for Biomedical Science of Pain, Beijing Key Laboratory for Neural Regeneration and Repairing, Department of Neurobiology, Capital University of Medical Sciences, 10 You An Men Wai Xi Tou Tiao, Beijing 100054, China
    Neurosci Lett 397:307-12. 2006
  6. doi request reprint Increased phosphorylation of Ets-like transcription factor-1 in neurons of hypoxic preconditioned mice
    Jun Jiang
    Department of Neurobiology and Beijing Institute for Neuroscience, Capital Medical University, 10 You An Men Wai Xi Tou Tiao, 100069 Beijing, China
    Neurochem Res 34:1443-50. 2009
  7. ncbi request reprint Neuron-specific phosphorylation of c-Jun N-terminal kinase increased in the brain of hypoxic preconditioned mice
    Nan Zhang
    Institute for Biomedical Science of Pain, Beijing Key Laboratory for Neural Regeneration and Repairing, Department of Neurobiology, Capital Medical University, 10 You An Men Wai Xi Tou Tiao, Beijing 100069, China
    Neurosci Lett 423:219-24. 2007
  8. ncbi request reprint Increased membrane/nuclear translocation and phosphorylation of p90 KD ribosomal S6 kinase in the brain of hypoxic preconditioned mice
    Zhifeng Qi
    Department of Neurobiology, Beijing Key Laboratory for Neural Regeneration and Repairing, Institute for Biomedical Science of Pain, Capital Medical University, 10 You An Men Wai Xi Tou Tiao, Beijing 100069, Peoples Republic of China
    Neurochem Res 32:1450-9. 2007
  9. ncbi request reprint Cell type-specific activation of p38 MAPK in the brain regions of hypoxic preconditioned mice
    Xiangning Bu
    Institute for Biomedical Science of Pain, Beijing Key Laboratory for Neural Regeneration and Repairing, Department of Neurobiology, Capital Medical University, 10 You An Men Wai Xi Tou Tiao, Beijing 100069, China
    Neurochem Int 51:459-66. 2007
  10. ncbi request reprint Activations of nPKCepsilon and ERK1/2 were involved in oxygen-glucose deprivation-induced neuroprotection via NMDA receptors in hippocampal slices of mice
    Jun Jia
    Department of Physiology, Institute for Biomedical Science of Pain, Capital Medical University, Beijing 100069, China
    J Neurosurg Anesthesiol 19:18-24. 2007

Collaborators

  • Ping Huang
  • Hua Li
  • Li Yu
  • Weiwei Yang
  • Jing Wu
  • Nan Zhang
  • Detlef Balschun
  • Song Han
  • Li Fang
  • Xiangning Bu
  • Xiaoli Qi
  • Caixia Long
  • Zhifeng Qi
  • Pengyu Zu
  • Yanan Gao
  • Cuiying Liu
  • Jun Jiang
  • She Wei Guo
  • Weiwen Wang
  • Wenjuan Lin
  • Jun Jia
  • Massako Kadekaro
  • Yong Wei
  • Ningli Wang
  • Ge Gao
  • Li Zhao
  • Chenchen Niu
  • Kuo Ping Huang
  • Zhifeng Peng
  • Dongguo Li
  • Donglin Wang
  • Meng Sun
  • Hou You Yu
  • Xiaomin Wang
  • Cui Ying Gao
  • Lan Feng Zhao
  • Xiu Yu Cui
  • Yongzhong Lei
  • Jun Feng Hou
  • Yang Yuan An
  • Ming Gang Liu
  • Guangxiao Su
  • Ya Li Long
  • Rong Chu
  • Deyu Zheng
  • Zhuo Min Lu
  • Jun Chen
  • Li Ying Ren
  • Qingjun Lu
  • Yuqin Pan
  • Libin Jiang
  • Qunyuan Xu
  • Penyu Zu
  • Xiuyu Cui
  • Klaus G Reymann
  • Freesia L Huang
  • Tino Jäger

Detail Information

Publications23

  1. pmc Protein kinases mediate increment of the phosphorylation of cyclic AMP-responsive element binding protein in spinal cord of rats following capsaicin injection
    Jing Wu
    Department of Neurology, University of Texas Health Science Center, Houston, TX 77030 1501, USA
    Mol Pain 1:26. 2005
    ....
  2. ncbi request reprint Increased phosphorylation of neurogranin in the brain of hypoxic preconditioned mice
    Junfa Li
    Institute for Biomedical Science of Pain, Beijing Key Laboratory for Neural Regeneration and Repairing, Department of Neurobiology, Capital University of Medical Sciences, Beijing 100054, China
    Neurosci Lett 391:150-3. 2006
    ..05). These results suggest that neurogranin protein may be involved in the development of cerebral hypoxic preconditioning...
  3. ncbi request reprint Identification of protein kinase C isoforms involved in cerebral hypoxic preconditioning of mice
    Junfa Li
    Institute for Biomedical Science of Pain, Beijing Key Laboratory for Neural Regeneration and Repairing, Department of Neurobiology, Capital University of Medical Sciences, Beijing 100054, China
    Brain Res 1060:62-72. 2005
    ..These results indicate that activation of cPKCbetaII, gamma, and nPKCepsilon might be involved in the development of cerebral hypoxic preconditioning of mice...
  4. ncbi request reprint Increased isoform-specific membrane translocation of conventional and novel protein kinase C in human neuroblastoma SH-SY5Y cells following prolonged hypoxia
    Junfa Li
    Institute for Biomedical Science of Pain, Beijing Key Laboratory for Neural Regeneration and Repairing, Department of Neurobiology, Capital University of Medical Sciences, 10 You An Men Wai Xi Tou Tiao, Beijing 100054, China
    Brain Res 1093:25-32. 2006
    ..These results suggested that prolonged hypoxia may induce the activation of cPKCalpha, betaI, betaII, and nPKCepsilon by triggering their membrane translocation in SH-SY5Y cells...
  5. ncbi request reprint Decreased phosphorylation and protein expression of ERK1/2 in the brain of hypoxic preconditioned mice
    Caixia Long
    Institute for Biomedical Science of Pain, Beijing Key Laboratory for Neural Regeneration and Repairing, Department of Neurobiology, Capital University of Medical Sciences, 10 You An Men Wai Xi Tou Tiao, Beijing 100054, China
    Neurosci Lett 397:307-12. 2006
    ..These results suggest that the decreased phosphorylation and downregulation of protein expression of ERK1/2 might be involved in the development of hypoxic preconditioning...
  6. doi request reprint Increased phosphorylation of Ets-like transcription factor-1 in neurons of hypoxic preconditioned mice
    Jun Jiang
    Department of Neurobiology and Beijing Institute for Neuroscience, Capital Medical University, 10 You An Men Wai Xi Tou Tiao, 100069 Beijing, China
    Neurochem Res 34:1443-50. 2009
    ..These results suggested that the enhanced neuron-specific phosphorylation of Elk-1 at Ser383 is involved in cerebral HPC of mice...
  7. ncbi request reprint Neuron-specific phosphorylation of c-Jun N-terminal kinase increased in the brain of hypoxic preconditioned mice
    Nan Zhang
    Institute for Biomedical Science of Pain, Beijing Key Laboratory for Neural Regeneration and Repairing, Department of Neurobiology, Capital Medical University, 10 You An Men Wai Xi Tou Tiao, Beijing 100069, China
    Neurosci Lett 423:219-24. 2007
    ..These results suggest that the increased neuron-specific phosphorylation of JNK at Thr183/Tyr185, not protein expression, might be involved in the development of cerebral HPC of mice...
  8. ncbi request reprint Increased membrane/nuclear translocation and phosphorylation of p90 KD ribosomal S6 kinase in the brain of hypoxic preconditioned mice
    Zhifeng Qi
    Department of Neurobiology, Beijing Key Laboratory for Neural Regeneration and Repairing, Institute for Biomedical Science of Pain, Capital Medical University, 10 You An Men Wai Xi Tou Tiao, Beijing 100069, Peoples Republic of China
    Neurochem Res 32:1450-9. 2007
    ..These results suggest that increased RSK membrane/nuclear translocation and PDK1 mediated neuron-specific phosphorylation of RSK at Ser227 might be involved in the development of cerebral HPC of mice...
  9. ncbi request reprint Cell type-specific activation of p38 MAPK in the brain regions of hypoxic preconditioned mice
    Xiangning Bu
    Institute for Biomedical Science of Pain, Beijing Key Laboratory for Neural Regeneration and Repairing, Department of Neurobiology, Capital Medical University, 10 You An Men Wai Xi Tou Tiao, Beijing 100069, China
    Neurochem Int 51:459-66. 2007
    ..These results suggest that the cell type-specific activation of p38 MAPK in the specific brain regions might contribute to the development of cerebral HPC mechanism in mice...
  10. ncbi request reprint Activations of nPKCepsilon and ERK1/2 were involved in oxygen-glucose deprivation-induced neuroprotection via NMDA receptors in hippocampal slices of mice
    Jun Jia
    Department of Physiology, Institute for Biomedical Science of Pain, Capital Medical University, Beijing 100069, China
    J Neurosurg Anesthesiol 19:18-24. 2007
    ..These results suggest that OGD10-induced neuroprotection against severe OGD45 in the Cornu Ammonis region 1 region of the hippocampal slices was mediated by the activations of NMDA receptors, nPKCepsilon, and the downstream ERKs...
  11. ncbi request reprint Changes in cPKC isoform-specific membrane translocation and protein expression in the brain of hypoxic preconditioned mice
    Chenchen Niu
    Institute for Biomedical Sciences of Pain, Department of Neurobiology, College of Basic Medicine, Capital University of Medical Sciences, Beijing 100054, China
    Neurosci Lett 384:1-6. 2005
    ....
  12. ncbi request reprint Enhanced phosphorylation of cyclic AMP response element binding protein in the brain of mice following repetitive hypoxic exposure
    Yanan Gao
    Institute for Biomedical Science of Pain, Beijing Key Laboratory for Neural Regeneration and Repairing, Department of Neurobiology, Capital University of Medical Sciences, Beijing 100054, China
    Biochem Biophys Res Commun 340:661-7. 2006
    ..These results suggest that the phosphorylation of CREB might be involved in the development of cerebral hypoxic preconditioning...
  13. doi request reprint Identification of differentially expressed microRNAs and their PKC-isoform specific gene network prediction during hypoxic pre-conditioning and focal cerebral ischemia of mice
    Cuiying Liu
    Department of Neurobiology, School of Basic Medical Sciences and School of Biomedical Engineering, Capital Medical University, Beijing, China
    J Neurochem 120:830-41. 2012
    ..These results suggested that the identified 19 miRNAs, notably miR-615-3p, might target these genes of cPKCβII, γ and nPKCε-interacting proteins involved in HPC-induced neuroprotection...
  14. ncbi request reprint Neuron-specific phosphorylation of mitogen- and stress-activated protein kinase-1 involved in cerebral hypoxic preconditioning of mice
    Ping Huang
    Institute for Biomedical Science of Pain, Beijing Key Laboratory for Neural Regeneration and Repairing, Department of Neurobiology, Capital Medical University, Beijing, China
    J Neurosci Res 85:1279-87. 2007
    ..These results suggest that the increased neuron-specific phosphorylation of MSK1 on Thr645 and Ser375, not protein expression, might be involved in the development of cerebral I/HPC in mice...
  15. ncbi request reprint Unilateral optic nerve transection up-regulate Hsp70 protein expression in lateral geniculate nucleus of rats
    Li Zhao
    Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital University of Medical Sciences, China
    Neurosci Lett 404:44-9. 2006
    ..These results suggest that increased expression of Hsp70 may be involved in protecting neurons within LGN against damage or loss induced by left optic nerve transection at early stage...
  16. ncbi request reprint Attenuation of protein kinase C and cAMP-dependent protein kinase signal transduction in the neurogranin knockout mouse
    Junfang Wu
    Section on Metabolic Regulation, Endocrinology and Reproduction Research Branch, NICHD, National Institutes of Health, Bethesda, Maryland 20892 4510, USA
    J Biol Chem 277:19498-505. 2002
    ....
  17. pmc The role of c-AMP-dependent protein kinase in spinal cord and post synaptic dorsal column neurons in a rat model of visceral pain
    Jing Wu
    Department of Neurology, University of Texas Health Science Center, Houston, TX 77030, United States
    Neurochem Int 50:710-8. 2007
    ..The results of our study suggest that the PKA signal transduction cascade may contribute to visceral nociceptive changes in spinal PSDC pathways...
  18. pmc Region- or state-related differences in expression and activation of extracellular signal-regulated kinases (ERKs) in naïve and pain-experiencing rats
    She Wei Guo
    Institute for Biomedical Sciences of Pain, Capital Medical University, Beijing 100069, PR China
    BMC Neurosci 8:53. 2007
    ....
  19. ncbi request reprint The depressive-like behaviors are correlated with decreased phosphorylation of mitogen-activated protein kinases in rat brain following chronic forced swim stress
    Xiaoli Qi
    Brain Behavior Research Center, Institute of Psychology, Chinese Academy of Science, Beijing 100101, China
    Behav Brain Res 175:233-40. 2006
    ..The depressive-like behaviors were correlated with decreased phosphorylation of Erk, which suggested that the dysfunction of Erk activity might be one of biological mechanisms underlying depression induced by stress...
  20. ncbi request reprint Enhanced protein expressions of sortilin and p75NTR in retina of rat following elevated intraocular pressure-induced retinal ischemia
    Yong Wei
    Beijing Tongren Eye Center, Beijing Tongren Hospital Vision Science Laboratory, School of Ophthalmology, Capital Medical University, Beijing 100730, China
    Neurosci Lett 429:169-74. 2007
    ..These results suggested that the protein expressions of 60 and 50 kDa forms of p75(NTR), and the 90 kDa mature form of sortilin increased in ischemia-induced retinal neuron of rats...
  21. doi request reprint Fluoxetine increases the activity of the ERK-CREB signal system and alleviates the depressive-like behavior in rats exposed to chronic forced swim stress
    Xiaoli Qi
    Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Science, Beijing, 100101, China
    Neurobiol Dis 31:278-85. 2008
    ..These results suggest that the ERK-CREB signal system may be the targets of the antidepressant action of fluoxetine and participate in the neuronal mechanism of depression...
  22. ncbi request reprint Neurogranin/RC3 enhances long-term potentiation and learning by promoting calcium-mediated signaling
    Kuo Ping Huang
    Section on Metabolic Regulation, Endocrinology and Reproduction Research Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892 4510, USA
    J Neurosci 24:10660-9. 2004
    ..This mechanism provides potent signal amplification in enhancing synaptic plasticity as well as learning and memory...
  23. pmc Effects of nitric oxide on expressions of nitrosocysteine and calcium-activated potassium channels in the supraoptic nuclei and neural lobe of dehydrated rats
    Massako Kadekaro
    Division of Neurosurgery, Department of Surgery, The University of Texas Medical Branch, Galveston, TX 77555, USA
    Neurosci Lett 411:117-22. 2007
    ..Our results indicate that NO signaling cascade may control the expression of BK channels through the regulation of nitrosocysteine in SON and neural lobe of rats during osmotic regulation...