Yimei Cao

Summary

Country: China

Publications

  1. pmc A pseudotype baculovirus expressing the capsid protein of foot-and-mouth disease virus and a T-cell immunogen shows enhanced immunogenicity in mice
    Yimei Cao
    Lanzhou Veterinary Research Institute of Chinese Academy of Agriculture Science, State Key Laboratory of Veterinary Etiological Biology, National Foot and mouth Disease Reference Laboratory, Key Laboratory of Animal Virology of Ministry of Agriculture, Xujiaping No 1, Yanchangpu, Lanzhou, Gansu 730046, PR China
    Virol J 8:77. 2011
  2. doi request reprint Poly(I:C) combined with multi-epitope protein vaccine completely protects against virulent foot-and-mouth disease virus challenge in pigs
    Yimei Cao
    State Key Laboratory of Veterinary Etiological Biology, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, China
    Antiviral Res 97:145-53. 2013
  3. doi request reprint Improved neutralising antibody response against foot-and-mouth-disease virus in mice inoculated with a multi-epitope peptide vaccine using polyinosinic and poly-cytidylic acid as an adjuvant
    Yimei Cao
    State Key Laboratory of Veterinary Etiological Biology, National Foot and Mouth Disease Reference Laboratory of China, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou 730046, China
    J Virol Methods 185:124-8. 2012
  4. pmc Development and validation of a prokaryotically expressed foot-and-mouth disease virus non-structural protein 2C'3AB-based immunochromatographic strip to differentiate between infected and vaccinated animals
    Lei Wu
    State Key Laboratory of Veterinary Etiologic Biology, National Foot and Mouth Disease Reference Laboratory of China, Key Laboratory of Animal Virology of Ministry of Agriculture, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, 730046, Gansu, China
    Virol J 8:186. 2011
  5. ncbi request reprint [Cloning and expression of 3C protease gene from foot-and-mouth disease virus in insect cell]
    Yimei Cao
    Lanzhou Veterinary Research Institute of Chinese Academy of Agricultural Science, State Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Animal Virology of Ministry of Agriculture, Lanzhou, 730046, China
    Wei Sheng Wu Xue Bao 48:312-6. 2008
  6. doi request reprint Protection of guinea pigs and swine by a recombinant adenovirus expressing O serotype of foot-and-mouth disease virus whole capsid and 3C protease
    Zengjun Lu
    Lanzhou Veterinary Research Institute of Chinese Academy of Agriculture Science, Xujiaping No 1, Yanchangpu, Lanzhou, Gansu 730046, People s Republic of China
    Vaccine 26:G48-53. 2008
  7. doi request reprint Synthesis of empty capsid-like particles of Asia I foot-and-mouth disease virus in insect cells and their immunogenicity in guinea pigs
    Yimei Cao
    Lanzhou Veterinary Research Institute of Chinese Academy of Agriculture Science, State Key Laboratory of Veterinary Etiological Biology, National Foot and mouth Disease Reference Laboratory, Yanchangpu, Lanzhou, Gansu, The People s Republic of China
    Vet Microbiol 137:10-7. 2009
  8. pmc Genetic characterization of the cell-adapted PanAsia strain of foot-and-mouth disease virus O/Fujian/CHA/5/99 isolated from swine
    Xingwen Bai
    National Foot and mouth Disease Reference Laboratory, State Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Animal Virology of the Ministry of Agriculture, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, Gansu 730046, PR China
    Virol J 7:208. 2010
  9. doi request reprint Development of a dot immunoblot method for differentiation of animals infected with foot-and-mouth disease virus from vaccinated animals using non-structural proteins expressed prokaryotically
    Yuanfang Fu
    Lanzhou Veterinary Research Institute of Chinese Academy of Agriculture Science, State Key Laboratory of Veterinary Etiological Biology, Lanzhou, Gansu, China
    J Virol Methods 171:234-40. 2011
  10. pmc Phylogenetic analysis of porcine parvoviruses from swine samples in China
    Xiaofang Hao
    State Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Animal Virology of Ministry of Agriculture, Lanzhou Veterinary Research Institute, Chinese Academy of Agriculture Sciences, Lanzhou, Gansu 730046, PR China
    Virol J 8:320. 2011

Detail Information

Publications22

  1. pmc A pseudotype baculovirus expressing the capsid protein of foot-and-mouth disease virus and a T-cell immunogen shows enhanced immunogenicity in mice
    Yimei Cao
    Lanzhou Veterinary Research Institute of Chinese Academy of Agriculture Science, State Key Laboratory of Veterinary Etiological Biology, National Foot and mouth Disease Reference Laboratory, Key Laboratory of Animal Virology of Ministry of Agriculture, Xujiaping No 1, Yanchangpu, Lanzhou, Gansu 730046, PR China
    Virol J 8:77. 2011
    ..Currently, inactivated vaccine of FMDV has been used in many countries with limited success and safety concerns. Development of a novel effective vaccine is must...
  2. doi request reprint Poly(I:C) combined with multi-epitope protein vaccine completely protects against virulent foot-and-mouth disease virus challenge in pigs
    Yimei Cao
    State Key Laboratory of Veterinary Etiological Biology, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, China
    Antiviral Res 97:145-53. 2013
    ..We propose that poly(I:C) is an effective adjuvant for this epitope-based vaccine of FMDV. This combination could yield an effective and safe candidate vaccine for the control and eradication of FMD in pigs...
  3. doi request reprint Improved neutralising antibody response against foot-and-mouth-disease virus in mice inoculated with a multi-epitope peptide vaccine using polyinosinic and poly-cytidylic acid as an adjuvant
    Yimei Cao
    State Key Laboratory of Veterinary Etiological Biology, National Foot and Mouth Disease Reference Laboratory of China, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou 730046, China
    J Virol Methods 185:124-8. 2012
    ..This combination could yield a promising vaccine for the prevention and control of FMD. Further study is needed to evaluate the efficiency of this combination on animals susceptible naturally to FMDV...
  4. pmc Development and validation of a prokaryotically expressed foot-and-mouth disease virus non-structural protein 2C'3AB-based immunochromatographic strip to differentiate between infected and vaccinated animals
    Lei Wu
    State Key Laboratory of Veterinary Etiologic Biology, National Foot and Mouth Disease Reference Laboratory of China, Key Laboratory of Animal Virology of Ministry of Agriculture, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, 730046, Gansu, China
    Virol J 8:186. 2011
    ..The use of the immunochromatographic strip is facile for clinical laboratories lacking specialized equipment and for rapid field diagnosis...
  5. ncbi request reprint [Cloning and expression of 3C protease gene from foot-and-mouth disease virus in insect cell]
    Yimei Cao
    Lanzhou Veterinary Research Institute of Chinese Academy of Agricultural Science, State Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Animal Virology of Ministry of Agriculture, Lanzhou, 730046, China
    Wei Sheng Wu Xue Bao 48:312-6. 2008
    ..The product was a 23 kDa protein and could be recognized by anti-FMDV serum in western blot. The results provide a basis for research of the assembly of FMDV empty capsids in vitro and the design of antivirus drug...
  6. doi request reprint Protection of guinea pigs and swine by a recombinant adenovirus expressing O serotype of foot-and-mouth disease virus whole capsid and 3C protease
    Zengjun Lu
    Lanzhou Veterinary Research Institute of Chinese Academy of Agriculture Science, Xujiaping No 1, Yanchangpu, Lanzhou, Gansu 730046, People s Republic of China
    Vaccine 26:G48-53. 2008
    ..The immune effect of Ad-P12x3C in swine further indicated that the recombinant adenovirus was highly efficient in transferring the foreign gene. This approach may thus be a very hopeful tool for developing FMD live virus vector vaccine...
  7. doi request reprint Synthesis of empty capsid-like particles of Asia I foot-and-mouth disease virus in insect cells and their immunogenicity in guinea pigs
    Yimei Cao
    Lanzhou Veterinary Research Institute of Chinese Academy of Agriculture Science, State Key Laboratory of Veterinary Etiological Biology, National Foot and mouth Disease Reference Laboratory, Yanchangpu, Lanzhou, Gansu, The People s Republic of China
    Vet Microbiol 137:10-7. 2009
    ..These recombinant, non-infectious, FMDV empty capsids are potentially useful for the development of new diagnostic techniques and vaccines...
  8. pmc Genetic characterization of the cell-adapted PanAsia strain of foot-and-mouth disease virus O/Fujian/CHA/5/99 isolated from swine
    Xingwen Bai
    National Foot and mouth Disease Reference Laboratory, State Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Animal Virology of the Ministry of Agriculture, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, Gansu 730046, PR China
    Virol J 7:208. 2010
    ..In addition, a molecular modeling was carried out with the external capsid proteins...
  9. doi request reprint Development of a dot immunoblot method for differentiation of animals infected with foot-and-mouth disease virus from vaccinated animals using non-structural proteins expressed prokaryotically
    Yuanfang Fu
    Lanzhou Veterinary Research Institute of Chinese Academy of Agriculture Science, State Key Laboratory of Veterinary Etiological Biology, Lanzhou, Gansu, China
    J Virol Methods 171:234-40. 2011
    ..Meanwhile, high rates of concordance were observed between the dot blot and the PrioCHECK® FMDV-NS test. The dot blot has the potential to act as a confirmatory method for DIVA by 3ABC-ELISA...
  10. pmc Phylogenetic analysis of porcine parvoviruses from swine samples in China
    Xiaofang Hao
    State Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Animal Virology of Ministry of Agriculture, Lanzhou Veterinary Research Institute, Chinese Academy of Agriculture Sciences, Lanzhou, Gansu 730046, PR China
    Virol J 8:320. 2011
    ..The data used in this study contained the available sequences for NS1 and VP2 from GenBank, as well as the two aforementioned Chinese strains...
  11. pmc Evaluation of a genetically modified foot-and-mouth disease virus vaccine candidate generated by reverse genetics
    Pinghua Li
    State Key Laboratory of Veterinary Etiological Biology, National Foot and mouth Disease Reference Laboratory, Key Laboratory of Animal Virology of Ministry of Agriculture, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, Gansu, China
    BMC Vet Res 8:57. 2012
    ..Therefore, the choice of a new vaccine strain is of fundamental importance...
  12. doi request reprint Expression of the major epitope regions of 2C integrated with the 3AB non-structural protein of foot-and-mouth disease virus and its potential for differentiating infected from vaccinated animals
    Zengjun Lu
    Lanzhou Veterinary Research Institute of Chinese Academy of Agriculture Science, State Key Laboratory of Veterinary Etiological Biology, National Foot and mouth Disease Reference Laboratory, Key Laboratory of Animal Virology of Ministry of Agriculture, Xujiaping No 1, Yanchangpu, Lanzhou, Gansu, China
    J Virol Methods 170:128-33. 2010
    ..This study indicates that the 2C3AB-ELISA can be used to confirm the results of the 3ABC-ELISA to improve the performance of the 3ABC-ELISA DIVA test...
  13. ncbi request reprint Evaluation of cross-protection against three topotypes of serotype O foot-and-mouth disease virus in pigs vaccinated with multi-epitope protein vaccine incorporated with poly(I:C)
    Yimei Cao
    State Key Laboratory of Veterinary Etiological Biology, National Foot and Mouth Disease Reference Laboratory of China, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Xujiaping No 1, Yanchangpu, Gansu, Lanzhou 730046, People s Republic of China
    Vet Microbiol 168:294-301. 2014
    ..These results showed that vaccination with multi-epitope protein vaccine incorporated with poly(I:C) can efficiently prevent FMD in pigs...
  14. doi request reprint Formation of virus-like particles from O-type foot-and-mouth disease virus in insect cells using codon-optimized synthetic genes
    Yimei Cao
    Lanzhou Veterinary Research Institute of Chinese Academy of Agriculture Science, State Key Laboratory of Veterinary Etiological Biology, National Foot and mouth Disease Reference Laboratory, Key Laboratory of Animal Virology of Ministry of Agriculture, Xujiaping No 1, Yanchangpu, Lanzhou 730046, Gansu, The People s Republic of China
    Biotechnol Lett 32:1223-9. 2010
    ..This information should prove useful for the development of more efficient VLP assembly using shorter genes...
  15. ncbi request reprint [Enhanced immune response of a novel T-cell immunogen in vaccine for foot-and-mouth disease]
    Qing Zhao
    National Foot and Mouth Disease Reference Laboratory of China, State Key Laboratory of Veterinary Etiological Biology, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou 730046, China
    Sheng Wu Gong Cheng Xue Bao 27:1281-91. 2011
    ..01). TI immunogen was an effective stimulator for humoral and cellular immunity and could help improve the immunogenicity of inactivated vaccine or protein subunit vaccine...
  16. doi request reprint Engineering infectious foot-and-mouth disease virus in vivo from a full-length genomic cDNA clone of the A/AKT/58 strain
    Xingwen Bai
    Key Laboratory of Animal Virology of Ministry of Agriculture, Lanzhou Veterinary Research Institute of Chinese Academy of Agricultural Sciences, Lanzhou, 730046, China
    Sci China C Life Sci 52:155-62. 2009
    ....
  17. ncbi request reprint [Purification and reactivity of foot-and-mouth disease virus non-structural protein 3A, 3B and 2C expressed in E. coli]
    Yuanfang Fu
    State Key Laboratory of Veterinary Etiological Biology, National Foot and mouth Disease Reference Laboratory, Lanzhou Veterinary Research Institute of Chinese Academy of Agriculture Science, Lanzhou, China
    Wei Sheng Wu Xue Bao 48:790-5. 2008
    ..To purify and to detect reactivity of non-structural proteins 3A, 3B and 2C expressed in the Escherichia coli...
  18. pmc Evaluation of a 3A-truncated foot-and-mouth disease virus in pigs for its potential as a marker vaccine
    Pinghua Li
    State Key Laboratory of Veterinary Etiological Biology, National Foot and mouth Disease Reference Laboratory, Key Laboratory of Animal Virology of Ministry of Agriculture, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, NO, 1 Xujiaping, Yanchangbao, Lanzhou, Gansu 730046, PR China
    Vet Res 45:51. 2014
    ..These results indicate that a marker FMDV vaccine can be potentially developed by deleting an immunodominant epitope in NSP 3A...
  19. pmc Polymorphic genetic characterization of the ORF7 gene of porcine reproductive and respiratory syndrome virus (PRRSV) in China
    Xiaofang Hao
    State Key Laboratory of Veterinary Etiological Biology, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, NO, 1 Xujiaping, Yanchangbao, Lanzhou, Gansu 730046, PR China
    Virol J 8:73. 2011
    ..The outbreak of a highly pathogenic PRRS in 2006 led us to investigate the extent of PRRSV genetic diversity in China. To this end, we analyzed the Nsp2 and ORF7 gene sequences of 98 Chinese PRRSV isolates...
  20. pmc Expression and stability of foreign epitopes introduced into 3A nonstructural protein of foot-and-mouth disease virus
    Pinghua Li
    State Key Laboratory of Veterinary Etiological Biology, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, Gansu, China
    PLoS ONE 7:e41486. 2012
    ..In addition, mice experimentally infected with the epitope-tagged viruses could induce tag-specific antibodies. Our results demonstrate that FMDV can be used effectively as a viral vector for the delivery of foreign tags...
  21. ncbi request reprint [Virulence comparison of genetic engineering virus containing different length poly(C) tract of foot-and-mouth disease virus]
    Xingwen Bai
    Lanzhou Vet Research Inst of Chinese Academy of Agricultural Sciences, State Key Lab of Vet Etiological Biology, National Foot and Mouth Disease Ref Lab, Key Lab of Animal Virology of Ministry of Agriculture, Lanzhou 730046, China
    Wei Sheng Wu Xue Bao 48:1654-8. 2008
    ..Study the association of the length of poly(C) tract with virulence of foot-and-mouth disease virus...
  22. ncbi request reprint Development and validation of a 3ABC indirect ELISA for differentiation of foot-and-mouth disease virus infected from vaccinated animals
    Zengjun Lu
    Lanzhou Veterinary Research Institute, Chinese Academy of Agriculture Science, State Key Laboratory of Veterinary Etiological Biology, National Foot and mouth Disease Reference Laboratory, Xujiaping No 1, Yanchangpu, Lanzhou, Gansu, PR China
    Vet Microbiol 125:157-69. 2007
    ..The prevalence of 3ABC antibodies reached 71.4% in some diseased cattle herds. The further work is required to evaluation the performance of this method in different animal species and different field situations...