Lin Tao Cai

Summary

Country: China

Publications

  1. doi request reprint In situ crosslinked smart polypeptide nanoparticles for multistage responsive tumor-targeted drug delivery
    Huqiang Yi
    Guangdong Key Laboratory of Nanomedicine, Key Lab for Health Informatics of Chinese Academy of Sciences, Shenzhen Institutes of Advance Technology, Chinese Academy of Sciences, Shenzhen 518055, PR China
    Nanoscale 8:5985-95. 2016
  2. doi request reprint Iron oxide nanoparticles protected by NIR-active multidentate-polymers as multifunctional nanoprobes for NIRF/PA/MR trimodal imaging
    Yayun Wu
    Guangdong Key Laboratory of Nanomedicine, CAS Key Laboratory of Health Informatics, Shenzhen Bioactive Materials Engineering Lab for Medicine, Institute of Biomedicine and Biotechnology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, P R China
    Nanoscale 8:775-9. 2015
  3. doi request reprint Compact chelator-free Ni-integrated CuS nanoparticles with tunable near-infrared absorption and enhanced relaxivity for in vivo dual-modal photoacoustic/MR imaging
    Duyang Gao
    Guangdong Key Laboratory of Nanomedicine, CAS Key Laboratory for Health Informatics, Shenzhen Bioactive Materials Engineering Lab for Medicine, Institute of Biomedicine and Biotechnology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, P R China
    Nanoscale 7:17631-6. 2015
  4. doi request reprint Long-decay near-infrared-emitting doped quantum dots for lifetime-based in vivo pH imaging
    Chi Chen
    Guangdong Key Laboratory of Nanomedicine, CAS Key Laboratory of Health Informatics, Shenzhen Bioactive Materials Engineering Lab for Medicine, Institute of Biomedicine and Biotechnology Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, P R China
    Chem Commun (Camb) 51:11162-5. 2015
  5. doi request reprint ZEB1 knockdown mediated using polypeptide cationic micelles inhibits metastasis and effects sensitization to a chemotherapeutic drug for cancer therapy
    Shengtao Fang
    Guangdong Key Laboratory of Nanomedicine, Shenzhen Key Laboratory of Cancer Nanotechnology, Institute of Biomedicine and Biotechnology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, Guangdong, P R China
    Nanoscale 6:10084-94. 2014
  6. pmc Folate receptor-targeting gold nanoclusters as fluorescence enzyme mimetic nanoprobes for tumor molecular colocalization diagnosis
    Dehong Hu
    Guangdong Key Laboratory of Nanomedicine, CAS Key Laboratory of Health Informatics, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, China
    Theranostics 4:142-53. 2014
  7. doi request reprint Polypeptide micelles with dual pH activatable dyes for sensing cells and cancer imaging
    Ping Gong
    Guangdong Key Laboratory of Nanomedicine, Shenzhen Key Laboratory of Cancer Nanotechnology, Institute of Biomedicine and Biotechnology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, Guangdong, P R China
    Nanoscale 6:5416-24. 2014
  8. doi request reprint A near infrared fluorescence resonance energy transfer based aptamer biosensor for insulin detection in human plasma
    Yuhui Wang
    CAS Key Laboratory of Health Informatics, Guangdong Key Laboratory of Nanomedicine, Shenzhen Key Laboratory of Cancer Nanotechnology, Institute of Biomedicine and Biotechnology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, P R China
    Chem Commun (Camb) 50:811-3. 2014
  9. doi request reprint Dextran based sensitive theranostic nanoparticles for near-infrared imaging and photothermal therapy in vitro
    Peng Liu
    CAS Key Laboratory of Health Informatics, Institute of Biomedicine and Biotechnology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, PR China
    Chem Commun (Camb) 49:6143-5. 2013
  10. doi request reprint Hybrid gold-gadolinium nanoclusters for tumor-targeted NIRF/CT/MRI triple-modal imaging in vivo
    De Hong Hu
    Guangdong Key Laboratory of Nanomedicine, Shenzhen Key Laboratory of Cancer Nanotechnology, Institute of Biomedicine and Biotechnology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China
    Nanoscale 5:1624-8. 2013

Collaborators

  • Zonghai Sheng
  • Ping Gong
  • Pengfei Zhang
  • Duyang Gao
  • Dehong Hu
  • Guanhui Gao
  • Chi Chen
  • Huqiang Yi
  • Yifan Ma
  • Shengtao Fang
  • De Hong Hu
  • Yayun Wu
  • Peng Liu
  • Shuhong Lian
  • Yuhui Wang
  • Mingxing Li
  • Bihua Shi
  • Sha Li
  • Yi Fan Ma
  • Nan Sheng
  • Yong Yang
  • Chuansheng Li
  • Qian Wan
  • Wenjun Li
  • Chengbo Liu
  • Li Zhang
  • Liang Song
  • Yanan Wang
  • Yueting Yang
  • Lei Wu
  • Shu Hui Liu
  • Da Zhi Yang
  • Bi Wang
  • Peng Fei Zhang
  • Du Yang Gao
  • Caixia Yue
  • Sheng Tao Fang
  • Changchun Zeng
  • Mingbin Zheng
  • Cuifang Zheng
  • Songhao Liu
  • Jianfeng Huang
  • Yangyang Lu

Detail Information

Publications17

  1. doi request reprint In situ crosslinked smart polypeptide nanoparticles for multistage responsive tumor-targeted drug delivery
    Huqiang Yi
    Guangdong Key Laboratory of Nanomedicine, Key Lab for Health Informatics of Chinese Academy of Sciences, Shenzhen Institutes of Advance Technology, Chinese Academy of Sciences, Shenzhen 518055, PR China
    Nanoscale 8:5985-95. 2016
    ..Hence, these multistage responsive FD-NPs would serve as highly efficient drug vectors for targeted cancer chemotherapy. ..
  2. doi request reprint Iron oxide nanoparticles protected by NIR-active multidentate-polymers as multifunctional nanoprobes for NIRF/PA/MR trimodal imaging
    Yayun Wu
    Guangdong Key Laboratory of Nanomedicine, CAS Key Laboratory of Health Informatics, Shenzhen Bioactive Materials Engineering Lab for Medicine, Institute of Biomedicine and Biotechnology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, P R China
    Nanoscale 8:775-9. 2015
    ..The resulted multifunctional nanoprobes showed great potential as multimodal contrast agents for NIRF/PA/MR trimodal imaging in vivo. ..
  3. doi request reprint Compact chelator-free Ni-integrated CuS nanoparticles with tunable near-infrared absorption and enhanced relaxivity for in vivo dual-modal photoacoustic/MR imaging
    Duyang Gao
    Guangdong Key Laboratory of Nanomedicine, CAS Key Laboratory for Health Informatics, Shenzhen Bioactive Materials Engineering Lab for Medicine, Institute of Biomedicine and Biotechnology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, P R China
    Nanoscale 7:17631-6. 2015
    ..Due to these unique properties, chelator-free nanoparticles have been successfully applied for in vivo PA/MRI dual-modal imaging. ..
  4. doi request reprint Long-decay near-infrared-emitting doped quantum dots for lifetime-based in vivo pH imaging
    Chi Chen
    Guangdong Key Laboratory of Nanomedicine, CAS Key Laboratory of Health Informatics, Shenzhen Bioactive Materials Engineering Lab for Medicine, Institute of Biomedicine and Biotechnology Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, P R China
    Chem Commun (Camb) 51:11162-5. 2015
    ..5 to 7.0 with the maximum change in the fluorescence lifetime up to ∼600 nm, were synthesized as lifetime-based pH nanosensors for in vivo imaging...
  5. doi request reprint ZEB1 knockdown mediated using polypeptide cationic micelles inhibits metastasis and effects sensitization to a chemotherapeutic drug for cancer therapy
    Shengtao Fang
    Guangdong Key Laboratory of Nanomedicine, Shenzhen Key Laboratory of Cancer Nanotechnology, Institute of Biomedicine and Biotechnology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, Guangdong, P R China
    Nanoscale 6:10084-94. 2014
    ..These results demonstrated that the siRNA-NP or siRNA-DOX-NP complex targeting ZEB1 could be developed into a new therapeutic approach for non-small cell lung cancer (NSCLC) treatment. ..
  6. pmc Folate receptor-targeting gold nanoclusters as fluorescence enzyme mimetic nanoprobes for tumor molecular colocalization diagnosis
    Dehong Hu
    Guangdong Key Laboratory of Nanomedicine, CAS Key Laboratory of Health Informatics, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, China
    Theranostics 4:142-53. 2014
    ..By examining different clinical samples, we demonstrated that the nanoprobes could distinguish efficiently cancerous cells from normal cells, and exhibit a clinical potential for cancer diagnosis. ..
  7. doi request reprint Polypeptide micelles with dual pH activatable dyes for sensing cells and cancer imaging
    Ping Gong
    Guangdong Key Laboratory of Nanomedicine, Shenzhen Key Laboratory of Cancer Nanotechnology, Institute of Biomedicine and Biotechnology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, Guangdong, P R China
    Nanoscale 6:5416-24. 2014
    ..Moreover, single acid activatable fluorescent dye doped polypeptide nanoparticles that only contained RBLC can distinguish tumor tissue from normal tissue by monitoring the acidic extracellular environment. ..
  8. doi request reprint A near infrared fluorescence resonance energy transfer based aptamer biosensor for insulin detection in human plasma
    Yuhui Wang
    CAS Key Laboratory of Health Informatics, Guangdong Key Laboratory of Nanomedicine, Shenzhen Key Laboratory of Cancer Nanotechnology, Institute of Biomedicine and Biotechnology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, P R China
    Chem Commun (Camb) 50:811-3. 2014
    ..A new FRET model using near-infrared quantum-dots (NIR-QDs) and oxidized carbon nanoparticles (OCNPs) as the energy donor and acceptor was constructed and designed for insulin detection in complex human plasma. ..
  9. doi request reprint Dextran based sensitive theranostic nanoparticles for near-infrared imaging and photothermal therapy in vitro
    Peng Liu
    CAS Key Laboratory of Health Informatics, Institute of Biomedicine and Biotechnology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, PR China
    Chem Commun (Camb) 49:6143-5. 2013
    ..The nanoparticles could be activated from "OFF" to "ON" of NIR fluorescence in an intracellular environment and used for NIR imaging and photothermal therapy...
  10. doi request reprint Hybrid gold-gadolinium nanoclusters for tumor-targeted NIRF/CT/MRI triple-modal imaging in vivo
    De Hong Hu
    Guangdong Key Laboratory of Nanomedicine, Shenzhen Key Laboratory of Cancer Nanotechnology, Institute of Biomedicine and Biotechnology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China
    Nanoscale 5:1624-8. 2013
    ..Hence, the well-defined hybrid gold-gadolinium NCs provide a versatile nanoprobe for cancer targeted imaging and diagnosis in vivo...
  11. pmc Highly luminescent near-infrared-emitting gold nanoclusters with further natural etching: photoluminescence and Hg2+ detection
    Shuhong Lian
    Shenzhen Key Laboratory of Cancer Nanotechnology, CAS Key Lab of Health Informatics, Institute of Biomedicine and Biotechnology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, China
    Nanoscale Res Lett 7:348. 2012
    ..Our preliminary results illustrated that the highly luminescent NIR-emitting Au NCs would be an alternative probe for the detection of heavy metal ions in water and environmental monitoring...
  12. doi request reprint Cation exchange in aptamer-conjugated CdSe nanoclusters: a novel fluorescence signal amplification for cancer cell detection
    Zonghai Sheng
    CAS Key Lab of Health Informatics, Institute of Biomedicine and Biotechnology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, Guangdong, P R China
    Chem Commun (Camb) 48:4202-4. 2012
    ..Fluorescence signal amplification by cation exchange in aptamer-conjugated CdSe nanoclusters, a biological self-assembly of CdSe quantum dots, was developed as a novel method for cancer cell detection...
  13. doi request reprint DNase-activatable fluorescence probes visualizing the degradation of exogenous DNA in living cells
    Ping Gong
    CAS Key Lab of Health Informatics, Institute of Biomedical and Health Engineering, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, Guangdong, PR China
    Nanoscale 4:2454-62. 2012
    ..The well-designed probes might be useful in tracing the dynamic changes of exogenous DNA and nanocarriers in vitro and in vivo...
  14. pmc Optical sensing nanostructures for porous silicon rugate filters
    Sha Li
    CAS Key Lab of Health Informatics, Shenzhen Key Laboratory of Cancer Nanotechnology, Institute of Biomedical and Health Engineering, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Xueyuan Avenue 1068, Shenzhen University Town, Shenzhen, 518055, People s Republic of China
    Nanoscale Res Lett 7:79. 2012
    ..As the concentration increased, the slope of the regression line also increased. The C-PSRF sensors indicated the high sensitivity, quick response, perfect durability, reproducibility, and versatility in other organic gas sensing...
  15. doi request reprint A fast synthesis of near-infrared emitting CdTe/CdSe quantum dots with small hydrodynamic diameter for in vivo imaging probes
    Dehong Hu
    CAS Key Lab of Health Informatics, Institute of Biomedical and Health Engineering, Chinese Academy of Sciences, Shenzhen, 518055, Guangdong, PR China
    Nanoscale 3:4724-32. 2011
    ..Our preliminary results illustrated that the CdTe/CdSe NIR-QDs with small sizes would be an alternative probe for ultrasensitive, multicolor, and multiplex applications, especially for in vivo imaging applications...
  16. ncbi request reprint [Research advancement and prospects of nanotechnology in early diagnosis and treatment of cancer]
    De Hong Hu
    Key Laboratory for Biomedical Informatics and Health Engineering of the Chinese Academy of Sciences, Institute of Biomedical and Health Engineering, Shenzhen Institutes of Advanced Technology Chinese Academy of Science, Shenzhen, Guangdong, 518055, China
    Ai Zheng 28:1000-3. 2009
    ..This review focused on the progress of nanotechnology in early diagnosis and treatment of cancer...
  17. doi request reprint Highly selective fluorescent sensors for Hg(2+) based on bovine serum albumin-capped gold nanoclusters
    Dehong Hu
    Key Laboratory for Biomedical Informatics and Health Engineering, Institute of Biomedical and Health Engineering, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, PR China
    Analyst 135:1411-6. 2010
    ..The feasibility of the BSA-Au NCs sensor for Hg(2+) in different aqueous samples was demonstrated with satisfactory results. Moreover, the possible sensing Hg(2+) mechanism was also discussed...