Bian C, Zhao Y, Guo Q, Xiong Y, Cai W, Zhang J. Aromatase inhibitor letrozole downregulates steroid receptor coactivator-1 in specific brain regions that primarily related to memory, neuroendocrine and integration. J Steroid Biochem Mol Biol. 2014;141:37-43 pubmed publisher
..Furthermore, these potential central adverse effects of letrozole should be taken into serious considerations. ..