Yiguang Jin

Summary

Affiliation: Beijing Institute of Radiation Medicine
Location: Beijing, China
Summary:
Focusing on a novel drug delivery technology: self-assembled drug delivery systems (SADDS) involving prodrug, molecular self-assembly, and nanotechnology. SADDS can be defined as the nanoscale self-assemblies of amphiphilic prodrugs. Now we have performed the SADDS research about antivirals, anticancer drugs, anti-tuberculosis agent. One of them, CPZ, showed a very high anti-HIV activity and macrophage-targeting effect.

Publications

  1. request reprint
    Du L, Feng X, Xiang X, Jin Y. Wound Healing Effect of an in Situ Forming Hydrogel Loading Curcumin-Phospholipid Complex. Curr Drug Deliv. 2016;13:76-82 pubmed
    ..The epidermal recovery was highly improved by the CPC ISG compared to the control. The CPC ISG is a promising formulation as an effective wound healing dressing. ..
  2. Li M, Zhu L, Liu B, Du L, Jia X, Han L, et al. Tea tree oil nanoemulsions for inhalation therapies of bacterial and fungal pneumonia. Colloids Surf B Biointerfaces. 2016;141:408-416 pubmed publisher
    ..Taken together, our results show that the inhalable nanoTTOs are promising nanomedicines for local therapies of fungal and bacterial pneumonia with no obvious adverse events. ..
  3. Zhu L, Liu X, Du L, Jin Y. Preparation of asiaticoside-loaded coaxially electrospinning nanofibers and their effect on deep partial-thickness burn injury. Biomed Pharmacother. 2016;83:33-40 pubmed publisher
    ..Its healing effect on deep partial-thickness burn injury of rats was obvious. Asiaticoside-loaded coaxial nanofibers provide a novel promising option for treatment of deep partial-thickness burn injury. ..
  4. Ge P, Sheng F, Jin Y, Tong L, Du L, Zhang L, et al. Magnetic resonance imaging of osteosarcoma using a bis(alendronate)-based bone-targeted contrast agent. Biomed Pharmacother. 2016;84:423-429 pubmed publisher
    ..Furthermore, the contrast enhancement could also be found in the lung due to metastasis of osteosarcoma. Gd2-DTPA-BA plays a promising role in the diagnoses of osteosacomas, including the primary bone tumors and metastases. ..

Detail Information

Publications4