Research Topics
| Jian Feng ChenSummaryAffiliation: Beijing University of Chemical Technology Country: China Publications
| Collaborators
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Detail Information
Publications
Preparation and characterization of porous hollow silica nanoparticles for drug delivery applicationJian Feng Chen
College of Chemical Engineering, Research Center of the Ministry of Education for High Gravity Engineering and Technology, Beijing University of Chemical Technology, No 15 Bei San Huan Dong Road, Beijing 100029, China
Biomaterials 25:723-7. 2004..The BJH pore size distribution of PHSNP before and after entrapping cefradine was examined. Cefradine release profile from PHSNP followed a three-stage pattern and exhibited a delayed release effect...- Feasibility of preparing nanodrugs by high-gravity reactive precipitationJian Feng Chen
Research Centre, Ministry of Education for High Gravity Engineering and Technology, College of Chemical Engineering, Beijing University of Chemical Technology, 100029 Beijing, PR China
Int J Pharm 269:267-74. 2004..The results have demonstrated the feasibility to produce nanodrugs by the principle of acid-base precipitating reaction using HGRP... 
Mesoporous silica nanotubes coated with multilayered polyelectrolytes for pH-controlled drug releaseYun Jie Yang
Key Lab for Nanomaterials of the Ministry of Education, Beijing University of Chemical Technology, Bei San Huan Dong Road 15, Beijing 100029, People s Republic of China
Acta Biomater 6:3092-100. 2010..Thus, these hybrid composites could be potentially applicable as pH-controlled drug delivery systems...- Preparation of uniform prednisolone microcrystals by a controlled microprecipitation methodXiang Shan Li
Sin China Nano Technology Center, Key Lab for Nanomaterials, Ministry of Education, Beijing University of Chemical Technology, Beijing 100029, PR China
Int J Pharm 342:26-32. 2007..The dissolution tests showed that the hexagonal and tetragonal PDL microcrystals exhibited significantly enhanced dissolution property when compared to commercial micronized PDL... - Formation of bicalutamide nanodispersion for dissolution rate enhancementChan Li
Key Lab for Nanomaterials, Ministry of Education, Beijing University of Chemical Technology, Beijing 100029, PR China
Int J Pharm 404:257-63. 2011..It was proposed that the enhanced dissolution rate of bicalutamide nanodispersion contribute to high surface area and well-wetted state of drug particles... - Micronization of gemfibrozil by reactive precipitation processQiao Ping Huang
Sin China Nano Technology Center, Key Lab for Nanomaterials, Ministry of Education, Beijing University of Chemical Technology, Beijing 100029, PR China
Int J Pharm 360:58-64. 2008..6% of bulk GEM dissolved, proving that the dissolution property of ultrafine GEM was significantly enhanced when compared to commercial GEM owing to a decreased particle size and an increased specific surface area... - Liquid antisolvent preparation of amorphous cefuroxime axetil nanoparticles in a tube-in-tube microchannel reactorWen zhen Zhu
Key Laboratory for Nanomaterials, Ministry of Education, Beijing University of Chemical Technology, Beijing 100029, PR China
Int J Pharm 395:260-5. 2010..The MTMCR might offer a general and facile pathway for mass production of the nanoparticles of hydrophobic pharmaceuticals thanks to its high throughput capacity and excellent micromixing performance... - Preparation of ultrafine fenofibrate powder by solidification process from emulsionQiao Ping Huang
Sin China Nano Technology Center, Key Lab for Nanomaterials, Ministry of Education, Beijing University of Chemical Technology, Beijing 100029, PR China
Int J Pharm 368:160-4. 2009..1% of ultrafine FF was dissolved after 120 min, while there was only 38.1% of bulk drug dissolved, proving that the dissolution property of ultrafine FF was significantly improved when compared to commercial drug... - Micronization of silybin by the emulsion solvent diffusion methodZhi Bing Zhang
Sin China Nano Technology Center, Key Lab for Nanomaterials, Ministry of Education, Beijing University of Chemical Technology, Beijing, PR China
Int J Pharm 376:116-22. 2009..Dissolution tests demonstrated that both of the spherical and rod-shaped silybin particles exhibited significantly enhanced dissolution rate when compared to the commercial silybin powder... - Adsorption of avermectin on porous hollow silica nanoparticles by supercritical technologyZhu Zhu Li
Key Lab for Nanomaterials, Ministry of Education, Beijing University of Chemical Technology, Beijing 100029, P R China
J Nanosci Nanotechnol 7:535-41. 2007.... - Fabrication of inhalable spore like pharmaceutical particles for deep lung depositionZhi Gang Shen
Sin China Nano Technology Center, State Key Laboratory of Organic Inorganic Composites, Beijing University of Chemical Technology, Beijing 100029, PR China
Int J Pharm 430:98-103. 2012.... - Study of UV-shielding properties of novel porous hollow silica nanoparticle carriers for avermectinZhu Zhu Li
Key Lab for Nanomaterials, Ministry of Education, Beijing University of Chemical Technology, Beijing 100029, PR China
Pest Manag Sci 63:241-6. 2007..It thus appears that PHSN carriers have a promising future in applications requiring sustained pesticide release... - Nanosized bicalutamide and its molecular structure in solventsYuan Le
Key Lab for Nanomaterials, Ministry of Education, Beijing University of Chemical Technology, Beijing 100029, China
Int J Pharm 370:175-80. 2009..The solvent effects have been taken into account based on the polarizable continuum model (PCM). The computed results appear that the introduction of dielectric medium has obvious effect on the molecular geometry of bicalutamide... - Fluorescent mesoporous silica nanotubes incorporating CdS quantum dots for controlled release of ibuprofenYun Jie Yang
Key Lab for Nanomaterials of Ministry of Education, Beijing University of Chemical Technology, Bei San Huan Dong Road 15, Beijing 100029, China
Acta Biomater 5:3488-96. 2009..e. borate buffer saline, pure water and normal saline, indicated that CdS-NH(2)-MSNTs are pH- and ion-sensitive drug carriers, which should facilitate controlled drug delivery and disease therapy... - Electronic structure and UV spectrum of fenofibrate in solutionsYuan Le
Key Laboratory for Nanomaterials, Ministry of Education, Beijing University of Chemical Technology, Beijing, PR China
Int J Pharm 358:214-8. 2008..The results demonstrate that TDDFT-PCM is a useful tool for study of the electronic absorption in solutions... - Micronization of atorvastatin calcium by antisolvent precipitation processHai Xia Zhang
Key Lab for Nanomaterials, Ministry of Education, Beijing University of Chemical Technology, Beijing, PR China
Int J Pharm 374:106-13. 2009..The XRD analyses indicated that the ultrafine AC was amorphous. In the dissolution tests, the amorphous AC ultrafine powder exhibited enhanced dissolution property when compared to the raw material... - Rose bengal-grafted biodegradable microcapsules: singlet-oxygen generation and cancer-cell incapacitationXiao lei Wang
State Key Laboratory of Organic Inorganic Composites, Beijing University of Chemical Technology, Beijing 100029, P R China
Chemistry 17:11223-9. 2011..In vitro cellular toxicity assays showed that RB-CHI-coated photosensitive microcapsules exhibit good biocompatibility in darkness and high cytotoxicity after irradiation, and could provide new photoresponsive drug-delivery vehicles... - Monodisperse Ag@SiO2 core-shell nanoparticles as active inhibitors for marine anticorrosion applicationsXin sheng Zhang
Key Lab for Nanomaterials, Ministry of Education, Beijing University of Chemical Technology, Beijing 100029, P R China
J Nanosci Nanotechnol 11:3481-7. 2011..Therefore, this would make monodisperse Ag@SiO2 core-shell nanoparticles a potential and promising corrosion inhibitor for developing future advanced multifunctional coatings... - Preparation of stable micron-sized crystalline irbesartan particles for the enhancement of dissolution rateZhi Liang Zhang
Key Lab for Nanomaterials, Ministry of Education, Beijing University of Chemical Technology, Beijing, PR China
Drug Dev Ind Pharm 37:1357-64. 2011..In this study, micron-sized crystalline drug particles of irbesartan (IBS) were prepared to improve its stability and dissolution rate... - Development of stabilized itraconazole nanodispersions by using high-gravity techniqueZhi Liang Zhang
State Key Laboratory of Organic Inorganic Composites, Beijing University of Chemical Technology, Beijing, PR China
Drug Dev Ind Pharm 38:1512-20. 2012..For large scale preparation of stabilized itraconazole (ITZ) nanodispersions to improve the dissolution rate... - Porous hollow silica nanoparticles as carriers for controlled delivery of ibuprofen to small intestineLi-Xiong Wen
Key Lab for Nanomaterials, Ministry of Education, Beijing University of Chemical Technology, Beijing 100029, PR China
J Nanosci Nanotechnol 6:3139-44. 2006..Therefore, the PHSNs can be utilized for applications of controlled drug delivery to small intestine... - Engineering drug ultrafine particles of beclomethasone dipropionate for dry powder inhalationLi Min Xu
State Key Laboratory of Organic Inorganic Composites, Beijing University of Chemical Technology, Beijing 100029, PR China
Int J Pharm 436:1-9. 2012..After spray drying, the BDP spherical aggregates with a 2-3 μm size could be achieved. They have an excellent aerosol performance, 2.8 and 1.4 times as many as raw BDP and vacuum-dried BDP particles, respectively... - Microfluidic synthesis of monodisperse Cu nanoparticles in aqueous solutionTe Ke
Key Lab for Nanomaterials, Ministry of Education, Beijing University of Chemical Technology, Beijing 100029, China
J Nanosci Nanotechnol 11:5154-8. 2011..In addition, with the unique microchannel structure, the throughput capability of the TMR for the production of Cu nanoparticles is up to several liters per minute... - Formulation and cytotoxicity of doxorubicin loaded in self-assembled bio-polyelectrolyte microshellsXia Tao
Key Lab for Nanomaterials of the Ministry of Education, Beijing University of Chemical Technology, Beijing 100029, China
Int J Pharm 336:376-81. 2007..Colorimetric XTT cell viability assay results showed that the DOX-loaded microshells at high concentrations tested could kill cancer cells more efficiently than free-DOX alone... - Fabrication of porous hollow silica nanoparticles and their applications in drug release controlZhu-Zhu Li
Key Lab for Nanomaterials, Ministry of Education, Research Center of the Ministry of Education for High Gravity Engineering and Technology, Beijing University of Chemical Technology, Beijing 100029, China
J Control Release 98:245-54. 2004..It showed that PHSN have a promising future in controlled drug delivery applications... - A functionally integrated device for effective and facile oil spill cleanupMengjiao Cheng
State Key Laboratory of Chemical Resource Engineering, Beijing University of Chemical Technology, Beijing 100029, PR China
Langmuir 27:7371-5. 2011.... - Dual-functional ZnO nanorod aggregates as scattering layer in the photoanode for dye-sensitized solar cellsYan Zhen Zheng
State Key Laboratory of Organic Inorganic Composites, Beijing University of Chemical Technology, Beijing 100029, China
Chem Commun (Camb) 47:11519-21. 2011.... - Silica nanotubes for lysozyme immobilizationHao-Min Ding
Key Lab for Nanomaterials, Ministry of Educations, Research Center of the Ministry of Education for High Gravity Engineering and Technology, Beijing University of Chemical Technology, Beijing 100029, People's Republic of China
J Colloid Interface Sci 290:102-6. 2005.... - Controlled release of avermectin from porous hollow silica nanoparticles: influence of shell thickness on loading efficiency, UV-shielding property and releaseZhu-Zhu Li
Key Lab for Nanomaterials, Ministry of Education, Beijing University of Chemical Technology, Beijing 100029, PR China
J Control Release 111:81-8. 2006.... - Toluidine red nanoparticles and their application in electrophoretic displayWu Wei An
Key Lab for Nanomaterial, Ministry of Education, Beijing University of Chemical Technology, Beijing 100029, China
J Nanosci Nanotechnol 11:10926-9. 2011..The prepared nanoparticles exhibit superior electrophoretic properties. Finally, the sedimentation of prepared particles dispersed into binary mixtures of tetrachloroethylene (C2Cl4) and cyclohexane is 4.76% for 2 months... - Selective hydrogenation of acetylene over egg-shell palladium nano-catalystQiu Feng Zhu
Key Lab for Nanomaterials, Ministry of Education, Beijing University of Chemical Technology, Beijing 100029, PR China
J Nanosci Nanotechnol 10:5641-7. 2010.... - Combining magnetic field induced locomotion and supramolecular interaction to micromanipulate glass fibers: toward assembly of complex structures at mesoscaleMengjiao Cheng
State Key Laboratory of Chemical Resource Engineering, Beijing University of Chemical Technology, Beijing 100029, PR China
Langmuir 27:6559-64. 2011..Moreover, we have constructed a mesoscale structure, termed "CHEM", to demonstrate further the application of this method... - Antibacterial activities of amorphous cefuroxime axetil ultrafine particles prepared by high gravity antisolvent precipitation (HGAP)Hong Zhao
Sin China Nano Technology Center, Key Lab for Nanomaterials, Ministry of Education, Beijing University of Chemical Technology, Beijing 10029, PR China
Pharm Dev Technol 14:485-91. 2009.... - Controlled release of avermectin from porous hollow silica nanoparticlesLi-Xiong Wen
Key Laboratory for Nanomaterials, Ministry of Education, Research Centre of the Ministry of Education for High Gravity Engineering and Technology, Beijing University of Chemical Technology, Beijing 100029, China
Pest Manag Sci 61:583-90. 2005..Increasing pH or temperature intensified the avermectin release... - Preparation of amorphous cefuroxime axetil nanoparticles by controlled nanoprecipitation method without surfactantsJi-Yao Zhang
Sin-China Nano Technology Center, Key Lab for Nanomaterials, Ministry of Education, Beijing University of Chemical Technology, Beijing 100029, PR China
Int J Pharm 323:153-60. 2006..The results demonstrated that the controlled nanoprecipitation method is a direct and feasible technology which could be utilized for preparation of the poorly water-soluble pharmaceutical nanoparticles... - Production of ultrafine sumatriptan succinate particles for pulmonary deliveryZong Yang Yang
Sin China Nano Technology Center, Key Lab for Nanomaterials, Ministry of Education, Beijing University of Chemical Technology, Beijing, 100029, People s Republic of China
Pharm Res 25:2012-8. 2008..Drug particle physical properties are critical for the efficiency of a drug delivered to the lung. The purpose of this study was to produce ultrafine sumatriptan succinate particles for inhalation... - Preparation of inhalable salbutamol sulphate using reactive high gravity controlled precipitationTingting Hu
Faculty of Pharmacy A15, The University of Sydney, Sydney, NSW 2006, Australia
J Pharm Sci 97:944-9. 2008..In conclusion, reactive HGCP followed by spray drying is suitable to produce stable crystalline powders of salbutamol with enhanced inhalation properties... - Production of salbutamol sulfate for inhalation by high-gravity controlled antisolvent precipitationHerbert Chiou
Faculty of Pharmacy A15, The University of Sydney, Sydney, NSW 2006, Australia
Int J Pharm 331:93-8. 2007..5+/-4.9% and 71.3+/-10.0%, respectively. In conclusion, SS powder with suitable physical and aerosol properties can be obtained through antisolvent HGCP followed by spray drying...