Jian Feng Chen

Summary

Affiliation: Beijing University of Chemical Technology
Country: China

Publications

  1. ncbi request reprint Preparation and characterization of porous hollow silica nanoparticles for drug delivery application
    Jian Feng Chen
    College of Chemical Engineering, Research Center of the Ministry of Education for High Gravity Engineering and Technology, Beijing University of Chemical Technology, No 15 Bei San Huan Dong Road, Beijing 100029, China
    Biomaterials 25:723-7. 2004
  2. ncbi request reprint Feasibility of preparing nanodrugs by high-gravity reactive precipitation
    Jian Feng Chen
    Research Centre, Ministry of Education for High Gravity Engineering and Technology, College of Chemical Engineering, Beijing University of Chemical Technology, 100029 Beijing, PR China
    Int J Pharm 269:267-74. 2004
  3. doi request reprint Can graphene quantum dots cause DNA damage in cells?
    Dan Wang
    State Key Laboratory of Organic Inorganic Composites, Beijing University of Chemical Technology, Beijing 100029, China
    Nanoscale 7:9894-901. 2015
  4. doi request reprint Mesoporous silica nanotubes coated with multilayered polyelectrolytes for pH-controlled drug release
    Yun Jie Yang
    Key Lab for Nanomaterials of the Ministry of Education, Beijing University of Chemical Technology, Bei San Huan Dong Road 15, Beijing 100029, People s Republic of China
    Acta Biomater 6:3092-100. 2010
  5. ncbi request reprint Controlled release of avermectin from porous hollow silica nanoparticles: influence of shell thickness on loading efficiency, UV-shielding property and release
    Zhu Zhu Li
    Key Lab for Nanomaterials, Ministry of Education, Beijing University of Chemical Technology, Beijing 100029, PR China
    J Control Release 111:81-8. 2006
  6. ncbi request reprint Preparation of uniform prednisolone microcrystals by a controlled microprecipitation method
    Xiang Shan Li
    Sin China Nano Technology Center, Key Lab for Nanomaterials, Ministry of Education, Beijing University of Chemical Technology, Beijing 100029, PR China
    Int J Pharm 342:26-32. 2007
  7. doi request reprint Formation of bicalutamide nanodispersion for dissolution rate enhancement
    Chan Li
    Key Lab for Nanomaterials, Ministry of Education, Beijing University of Chemical Technology, Beijing 100029, PR China
    Int J Pharm 404:257-63. 2011
  8. doi request reprint A novel strategy to produce highly stable and transparent aqueous 'nanosolutions' of water-insoluble drug molecules
    Jie Xin Wang
    State Key Laboratory of Organic Inorganic Composites, Beijing University of Chemical Technology, Beijing, People s Republic of China
    Nanotechnology 22:305101. 2011
  9. doi request reprint Micronization of gemfibrozil by reactive precipitation process
    Qiao Ping Huang
    Sin China Nano Technology Center, Key Lab for Nanomaterials, Ministry of Education, Beijing University of Chemical Technology, Beijing 100029, PR China
    Int J Pharm 360:58-64. 2008
  10. ncbi request reprint Preparation of amorphous cefuroxime axetil nanoparticles by controlled nanoprecipitation method without surfactants
    Ji Yao Zhang
    Sin China Nano Technology Center, Key Lab for Nanomaterials, Ministry of Education, Beijing University of Chemical Technology, Beijing 100029, PR China
    Int J Pharm 323:153-60. 2006

Collaborators

Detail Information

Publications50

  1. ncbi request reprint Preparation and characterization of porous hollow silica nanoparticles for drug delivery application
    Jian Feng Chen
    College of Chemical Engineering, Research Center of the Ministry of Education for High Gravity Engineering and Technology, Beijing University of Chemical Technology, No 15 Bei San Huan Dong Road, Beijing 100029, China
    Biomaterials 25:723-7. 2004
    ..The BJH pore size distribution of PHSNP before and after entrapping cefradine was examined. Cefradine release profile from PHSNP followed a three-stage pattern and exhibited a delayed release effect...
  2. ncbi request reprint Feasibility of preparing nanodrugs by high-gravity reactive precipitation
    Jian Feng Chen
    Research Centre, Ministry of Education for High Gravity Engineering and Technology, College of Chemical Engineering, Beijing University of Chemical Technology, 100029 Beijing, PR China
    Int J Pharm 269:267-74. 2004
    ..The results have demonstrated the feasibility to produce nanodrugs by the principle of acid-base precipitating reaction using HGRP...
  3. doi request reprint Can graphene quantum dots cause DNA damage in cells?
    Dan Wang
    State Key Laboratory of Organic Inorganic Composites, Beijing University of Chemical Technology, Beijing 100029, China
    Nanoscale 7:9894-901. 2015
    ..The GQD-induced release of reactive oxygen species (ROS) was demonstrated to be responsible for the observed DNA damage. These findings should have important implications for future applications of GQDs in biological systems. ..
  4. doi request reprint Mesoporous silica nanotubes coated with multilayered polyelectrolytes for pH-controlled drug release
    Yun Jie Yang
    Key Lab for Nanomaterials of the Ministry of Education, Beijing University of Chemical Technology, Bei San Huan Dong Road 15, Beijing 100029, People s Republic of China
    Acta Biomater 6:3092-100. 2010
    ..Thus, these hybrid composites could be potentially applicable as pH-controlled drug delivery systems...
  5. ncbi request reprint Controlled release of avermectin from porous hollow silica nanoparticles: influence of shell thickness on loading efficiency, UV-shielding property and release
    Zhu Zhu Li
    Key Lab for Nanomaterials, Ministry of Education, Beijing University of Chemical Technology, Beijing 100029, PR China
    J Control Release 111:81-8. 2006
    ....
  6. ncbi request reprint Preparation of uniform prednisolone microcrystals by a controlled microprecipitation method
    Xiang Shan Li
    Sin China Nano Technology Center, Key Lab for Nanomaterials, Ministry of Education, Beijing University of Chemical Technology, Beijing 100029, PR China
    Int J Pharm 342:26-32. 2007
    ..The dissolution tests showed that the hexagonal and tetragonal PDL microcrystals exhibited significantly enhanced dissolution property when compared to commercial micronized PDL...
  7. doi request reprint Formation of bicalutamide nanodispersion for dissolution rate enhancement
    Chan Li
    Key Lab for Nanomaterials, Ministry of Education, Beijing University of Chemical Technology, Beijing 100029, PR China
    Int J Pharm 404:257-63. 2011
    ..It was proposed that the enhanced dissolution rate of bicalutamide nanodispersion contribute to high surface area and well-wetted state of drug particles...
  8. doi request reprint A novel strategy to produce highly stable and transparent aqueous 'nanosolutions' of water-insoluble drug molecules
    Jie Xin Wang
    State Key Laboratory of Organic Inorganic Composites, Beijing University of Chemical Technology, Beijing, People s Republic of China
    Nanotechnology 22:305101. 2011
    ..This has great potential to offer a novel solution for innovative drugs of the future...
  9. doi request reprint Micronization of gemfibrozil by reactive precipitation process
    Qiao Ping Huang
    Sin China Nano Technology Center, Key Lab for Nanomaterials, Ministry of Education, Beijing University of Chemical Technology, Beijing 100029, PR China
    Int J Pharm 360:58-64. 2008
    ..6% of bulk GEM dissolved, proving that the dissolution property of ultrafine GEM was significantly enhanced when compared to commercial GEM owing to a decreased particle size and an increased specific surface area...
  10. ncbi request reprint Preparation of amorphous cefuroxime axetil nanoparticles by controlled nanoprecipitation method without surfactants
    Ji Yao Zhang
    Sin China Nano Technology Center, Key Lab for Nanomaterials, Ministry of Education, Beijing University of Chemical Technology, Beijing 100029, PR China
    Int J Pharm 323:153-60. 2006
    ..The results demonstrated that the controlled nanoprecipitation method is a direct and feasible technology which could be utilized for preparation of the poorly water-soluble pharmaceutical nanoparticles...
  11. ncbi request reprint Fabrication of porous hollow silica nanoparticles and their applications in drug release control
    Zhu Zhu Li
    Key Lab for Nanomaterials, Ministry of Education, Research Center of the Ministry of Education for High Gravity Engineering and Technology, Beijing University of Chemical Technology, Beijing 100029, China
    J Control Release 98:245-54. 2004
    ..It showed that PHSN have a promising future in controlled drug delivery applications...
  12. ncbi request reprint Porous hollow silica nanoparticles as carriers for controlled delivery of ibuprofen to small intestine
    Li Xiong Wen
    Key Lab for Nanomaterials, Ministry of Education, Beijing University of Chemical Technology, Beijing 100029, PR China
    J Nanosci Nanotechnol 6:3139-44. 2006
    ..Therefore, the PHSNs can be utilized for applications of controlled drug delivery to small intestine...
  13. doi request reprint Liquid antisolvent preparation of amorphous cefuroxime axetil nanoparticles in a tube-in-tube microchannel reactor
    Wen zhen Zhu
    Key Laboratory for Nanomaterials, Ministry of Education, Beijing University of Chemical Technology, Beijing 100029, PR China
    Int J Pharm 395:260-5. 2010
    ..The MTMCR might offer a general and facile pathway for mass production of the nanoparticles of hydrophobic pharmaceuticals thanks to its high throughput capacity and excellent micromixing performance...
  14. doi request reprint Development of stabilized itraconazole nanodispersions by using high-gravity technique
    Zhi Liang Zhang
    State Key Laboratory of Organic Inorganic Composites, Beijing University of Chemical Technology, Beijing, PR China
    Drug Dev Ind Pharm 38:1512-20. 2012
    ..For large scale preparation of stabilized itraconazole (ITZ) nanodispersions to improve the dissolution rate...
  15. ncbi request reprint Silica nanotubes for lysozyme immobilization
    Hao Min Ding
    Key Lab for Nanomaterials, Ministry of Educations, Research Center of the Ministry of Education for High Gravity Engineering and Technology, Beijing University of Chemical Technology, Beijing 100029, People s Republic of China
    J Colloid Interface Sci 290:102-6. 2005
    ....
  16. ncbi request reprint Controlled release of avermectin from porous hollow silica nanoparticles
    Li Xiong Wen
    Key Laboratory for Nanomaterials, Ministry of Education, Research Centre of the Ministry of Education for High Gravity Engineering and Technology, Beijing University of Chemical Technology, Beijing 100029, China
    Pest Manag Sci 61:583-90. 2005
    ..Increasing pH or temperature intensified the avermectin release...
  17. doi request reprint Micronization of silybin by the emulsion solvent diffusion method
    Zhi Bing Zhang
    Sin China Nano Technology Center, Key Lab for Nanomaterials, Ministry of Education, Beijing University of Chemical Technology, Beijing, PR China
    Int J Pharm 376:116-22. 2009
    ..Dissolution tests demonstrated that both of the spherical and rod-shaped silybin particles exhibited significantly enhanced dissolution rate when compared to the commercial silybin powder...
  18. doi request reprint Preparation of ultrafine fenofibrate powder by solidification process from emulsion
    Qiao Ping Huang
    Sin China Nano Technology Center, Key Lab for Nanomaterials, Ministry of Education, Beijing University of Chemical Technology, Beijing 100029, PR China
    Int J Pharm 368:160-4. 2009
    ..1% of ultrafine FF was dissolved after 120 min, while there was only 38.1% of bulk drug dissolved, proving that the dissolution property of ultrafine FF was significantly improved when compared to commercial drug...
  19. doi request reprint Studies of bicalutamide-excipients interaction by combination of molecular docking and molecular dynamics simulation
    Caixia Li
    State Key Laboratory of Organic Inorganic Composites, Beijing University of Chemical Technology, Beijing 100029, China
    Mol Pharm 10:2362-9. 2013
    ..It also holds the great potential to simplify the optimization process of drug delivery system and reduce both time and costs...
  20. ncbi request reprint Adsorption of avermectin on porous hollow silica nanoparticles by supercritical technology
    Zhu Zhu Li
    Key Lab for Nanomaterials, Ministry of Education, Beijing University of Chemical Technology, Beijing 100029, P R China
    J Nanosci Nanotechnol 7:535-41. 2007
    ....
  21. doi request reprint Fabrication of inhalable spore like pharmaceutical particles for deep lung deposition
    Zhi Gang Shen
    Sin China Nano Technology Center, State Key Laboratory of Organic Inorganic Composites, Beijing University of Chemical Technology, Beijing 100029, PR China
    Int J Pharm 430:98-103. 2012
    ....
  22. doi request reprint Nanosized bicalutamide and its molecular structure in solvents
    Yuan Le
    Key Lab for Nanomaterials, Ministry of Education, Beijing University of Chemical Technology, Beijing 100029, China
    Int J Pharm 370:175-80. 2009
    ..The solvent effects have been taken into account based on the polarizable continuum model (PCM). The computed results appear that the introduction of dielectric medium has obvious effect on the molecular geometry of bicalutamide...
  23. ncbi request reprint Study of UV-shielding properties of novel porous hollow silica nanoparticle carriers for avermectin
    Zhu Zhu Li
    Key Lab for Nanomaterials, Ministry of Education, Beijing University of Chemical Technology, Beijing 100029, PR China
    Pest Manag Sci 63:241-6. 2007
    ..It thus appears that PHSN carriers have a promising future in applications requiring sustained pesticide release...
  24. doi request reprint Fluorescent mesoporous silica nanotubes incorporating CdS quantum dots for controlled release of ibuprofen
    Yun Jie Yang
    Key Lab for Nanomaterials of Ministry of Education, Beijing University of Chemical Technology, Bei San Huan Dong Road 15, Beijing 100029, China
    Acta Biomater 5:3488-96. 2009
    ..e. borate buffer saline, pure water and normal saline, indicated that CdS-NH(2)-MSNTs are pH- and ion-sensitive drug carriers, which should facilitate controlled drug delivery and disease therapy...
  25. doi request reprint Electronic structure and UV spectrum of fenofibrate in solutions
    Yuan Le
    Key Laboratory for Nanomaterials, Ministry of Education, Beijing University of Chemical Technology, Beijing, PR China
    Int J Pharm 358:214-8. 2008
    ..The results demonstrate that TDDFT-PCM is a useful tool for study of the electronic absorption in solutions...
  26. doi request reprint Micronization of atorvastatin calcium by antisolvent precipitation process
    Hai Xia Zhang
    Key Lab for Nanomaterials, Ministry of Education, Beijing University of Chemical Technology, Beijing, PR China
    Int J Pharm 374:106-13. 2009
    ..The XRD analyses indicated that the ultrafine AC was amorphous. In the dissolution tests, the amorphous AC ultrafine powder exhibited enhanced dissolution property when compared to the raw material...
  27. doi request reprint Rose bengal-grafted biodegradable microcapsules: singlet-oxygen generation and cancer-cell incapacitation
    Xiao lei Wang
    State Key Laboratory of Organic Inorganic Composites, Beijing University of Chemical Technology, Beijing 100029, P R China
    Chemistry 17:11223-9. 2011
    ..In vitro cellular toxicity assays showed that RB-CHI-coated photosensitive microcapsules exhibit good biocompatibility in darkness and high cytotoxicity after irradiation, and could provide new photoresponsive drug-delivery vehicles...
  28. ncbi request reprint Monodisperse Ag@SiO2 core-shell nanoparticles as active inhibitors for marine anticorrosion applications
    Xin sheng Zhang
    Key Lab for Nanomaterials, Ministry of Education, Beijing University of Chemical Technology, Beijing 100029, P R China
    J Nanosci Nanotechnol 11:3481-7. 2011
    ..Therefore, this would make monodisperse Ag@SiO2 core-shell nanoparticles a potential and promising corrosion inhibitor for developing future advanced multifunctional coatings...
  29. doi request reprint Synergistic effect of PEGylated resveratrol on delivery of anticancer drugs
    Wenlong Wang
    State Key Laboratory of Organic Inorganic Composites, Beijing University of Chemical Technology, Beijing 100029, PR China
    Int J Pharm 498:134-41. 2016
    ..These results suggest that PEGylated RES conjugates show great potential for cancer therapy. ..
  30. doi request reprint Poly(amidoamine) dendrimer-grafted porous hollow silica nanoparticles for enhanced intracellular photodynamic therapy
    Xia Tao
    State Key Laboratory of Organic Inorganic Composites, Beijing University of Chemical Technology, Beijing 100029, People s Republic of China
    Acta Biomater 9:6431-8. 2013
    ....
  31. doi request reprint Engineering drug ultrafine particles of beclomethasone dipropionate for dry powder inhalation
    Li Min Xu
    State Key Laboratory of Organic Inorganic Composites, Beijing University of Chemical Technology, Beijing 100029, PR China
    Int J Pharm 436:1-9. 2012
    ..After spray drying, the BDP spherical aggregates with a 2-3 μm size could be achieved. They have an excellent aerosol performance, 2.8 and 1.4 times as many as raw BDP and vacuum-dried BDP particles, respectively...
  32. doi request reprint Preparation of stable micron-sized crystalline irbesartan particles for the enhancement of dissolution rate
    Zhi Liang Zhang
    Key Lab for Nanomaterials, Ministry of Education, Beijing University of Chemical Technology, Beijing, PR China
    Drug Dev Ind Pharm 37:1357-64. 2011
    ..In this study, micron-sized crystalline drug particles of irbesartan (IBS) were prepared to improve its stability and dissolution rate...
  33. doi request reprint Transparent 'solution' of ultrathin magnesium hydroxide nanocrystals for flexible and transparent nanocomposite films
    Jie Xin Wang
    State Key Laboratory of Organic Inorganic Composites, Beijing University of Chemical Technology, Beijing 100029, People s Republic of China
    Nanotechnology 26:195602. 2015
    ....
  34. doi request reprint Controllable assembly of well-defined monodisperse Au nanoparticles on hierarchical ZnO microspheres for enhanced visible-light-driven photocatalytic and antibacterial activity
    Yuan Wang
    State Key Laboratory of Organic Inorganic Composites, Beijing University of Chemical Technology, Beijing 100029, China
    Nanoscale 7:19118-28. 2015
    ....
  35. doi request reprint Characterizing the role of iodine doping in improving photovoltaic performance of dye-sensitized hierarchically structured ZnO solar cells
    Jia Xing Zhao
    State Key Laboratory of Organic Inorganic Composites, Beijing University of Chemical Technology, Beijing 100029, China
    Chemphyschem 14:1977-84. 2013
    ....
  36. ncbi request reprint Microfluidic synthesis of monodisperse Cu nanoparticles in aqueous solution
    Te Ke
    Key Lab for Nanomaterials, Ministry of Education, Beijing University of Chemical Technology, Beijing 100029, China
    J Nanosci Nanotechnol 11:5154-8. 2011
    ..In addition, with the unique microchannel structure, the throughput capability of the TMR for the production of Cu nanoparticles is up to several liters per minute...
  37. doi request reprint Structural Correspondence of the Oriented Attachment Growth Mechanism of Crystals of the Pharmaceutical Dirithromycin
    Zuozhong Liang
    State Key Laboratory of Organic Inorganic Composites, Research Center of the Ministry of Education for High Gravity Engineering and Technology, and Biomass Energy and Environmental Engineering Research Center, Beijing University of Chemical Technology, Beijing 100029, China
    Langmuir 31:13802-12. 2015
    ....
  38. doi request reprint Excipient-assisted vinpocetine nanoparticles: experiments and molecular dynamic simulations
    Cai xia Li
    State Key Laboratory of Organic Inorganic Composites, Beijing University of Chemical Technology, Beijing 100029, P R China
    Mol Pharm 11:4023-35. 2014
    ..These characteristics may greatly influence the adsorption behavior and may be the crucial parameter for the better performance of HPMC. ..
  39. doi request reprint Visible-Light-Responsive TiO2-Coated ZnO:I Nanorod Array Films with Enhanced Photoelectrochemical and Photocatalytic Performance
    Yuan Wang
    State Key Laboratory of Organic Inorganic Composites, Beijing University of Chemical Technology, Beijing 100029, China
    ACS Appl Mater Interfaces 7:6093-101. 2015
    ..Thus, ZnO:I/TiO2 NRs are considered a promising photocatalytic material to degrade organic pollutants in aqueous eco-environments. ..
  40. ncbi request reprint Formulation and cytotoxicity of doxorubicin loaded in self-assembled bio-polyelectrolyte microshells
    Xia Tao
    Key Lab for Nanomaterials of the Ministry of Education, Beijing University of Chemical Technology, Beijing 100029, China
    Int J Pharm 336:376-81. 2007
    ..Colorimetric XTT cell viability assay results showed that the DOX-loaded microshells at high concentrations tested could kill cancer cells more efficiently than free-DOX alone...
  41. ncbi request reprint Dual-functional ZnO nanorod aggregates as scattering layer in the photoanode for dye-sensitized solar cells
    Yan Zhen Zheng
    State Key Laboratory of Organic Inorganic Composites, Beijing University of Chemical Technology, Beijing 100029, China
    Chem Commun (Camb) 47:11519-21. 2011
    ....
  42. ncbi request reprint A functionally integrated device for effective and facile oil spill cleanup
    Mengjiao Cheng
    State Key Laboratory of Chemical Resource Engineering, Beijing University of Chemical Technology, Beijing 100029, PR China
    Langmuir 27:7371-5. 2011
    ....
  43. doi request reprint Poly(lactic acid)/chitosan hybrid nanoparticles for controlled release of anticancer drug
    Wenlong Wang
    State Key Laboratory of Organic Inorganic Composites, Beijing University of Chemical Technology, Beijing 100029, PR China
    Mater Sci Eng C Mater Biol Appl 46:514-20. 2015
    ..These results illustrated high potential of chitosan modified PLA nanoparticles for usage as anticancer drug carriers...
  44. ncbi request reprint Toluidine red nanoparticles and their application in electrophoretic display
    Wu Wei An
    Key Lab for Nanomaterial, Ministry of Education, Beijing University of Chemical Technology, Beijing 100029, China
    J Nanosci Nanotechnol 11:10926-9. 2011
    ..The prepared nanoparticles exhibit superior electrophoretic properties. Finally, the sedimentation of prepared particles dispersed into binary mixtures of tetrachloroethylene (C2Cl4) and cyclohexane is 4.76% for 2 months...
  45. ncbi request reprint Selective hydrogenation of acetylene over egg-shell palladium nano-catalyst
    Qiu Feng Zhu
    Key Lab for Nanomaterials, Ministry of Education, Beijing University of Chemical Technology, Beijing 100029, PR China
    J Nanosci Nanotechnol 10:5641-7. 2010
    ....
  46. doi request reprint Combining magnetic field induced locomotion and supramolecular interaction to micromanipulate glass fibers: toward assembly of complex structures at mesoscale
    Mengjiao Cheng
    State Key Laboratory of Chemical Resource Engineering, Beijing University of Chemical Technology, Beijing 100029, PR China
    Langmuir 27:6559-64. 2011
    ..Moreover, we have constructed a mesoscale structure, termed "CHEM", to demonstrate further the application of this method...
  47. doi request reprint Antibacterial activities of amorphous cefuroxime axetil ultrafine particles prepared by high gravity antisolvent precipitation (HGAP)
    Hong Zhao
    Sin China Nano Technology Center, Key Lab for Nanomaterials, Ministry of Education, Beijing University of Chemical Technology, Beijing 10029, PR China
    Pharm Dev Technol 14:485-91. 2009
    ....
  48. ncbi request reprint Production of salbutamol sulfate for inhalation by high-gravity controlled antisolvent precipitation
    Herbert Chiou
    Faculty of Pharmacy A15, The University of Sydney, Sydney, NSW 2006, Australia
    Int J Pharm 331:93-8. 2007
    ..5+/-4.9% and 71.3+/-10.0%, respectively. In conclusion, SS powder with suitable physical and aerosol properties can be obtained through antisolvent HGCP followed by spray drying...
  49. doi request reprint Production of ultrafine sumatriptan succinate particles for pulmonary delivery
    Zong Yang Yang
    Sin China Nano Technology Center, Key Lab for Nanomaterials, Ministry of Education, Beijing University of Chemical Technology, Beijing, 100029, People s Republic of China
    Pharm Res 25:2012-8. 2008
    ..Drug particle physical properties are critical for the efficiency of a drug delivered to the lung. The purpose of this study was to produce ultrafine sumatriptan succinate particles for inhalation...
  50. ncbi request reprint Preparation of inhalable salbutamol sulphate using reactive high gravity controlled precipitation
    Tingting Hu
    Faculty of Pharmacy A15, The University of Sydney, Sydney, NSW 2006, Australia
    J Pharm Sci 97:944-9. 2008
    ..In conclusion, reactive HGCP followed by spray drying is suitable to produce stable crystalline powders of salbutamol with enhanced inhalation properties...