Wu Chun Cao

Summary

Affiliation: Beijing Institute of Radiation Medicine
Country: China

Publications

  1. ncbi request reprint Prevalence of Anaplasma phagocytophila and Borrelia burgdorferi in Ixodes persulcatus ticks from northeastern China
    Wu Chun Cao
    Department of Epidemiology, Beijing Institute of Microbiology and Epidemiology, Fengtai District, Beijing, People s Republic of China
    Am J Trop Med Hyg 68:547-50. 2003
  2. ncbi request reprint A new Hantaan-like virus in rodents (Apodemus peninsulae) from Northeastern China
    Jia Fu Jiang
    Beijing Institute of Microbiology and Epidemiology, State Key Laboratory of Pathogen and Biosecurity, Beijing 100071, PR China
    Virus Res 130:292-5. 2007
  3. doi request reprint Presence of pathogenic Borrelia burgdorferi sensu lato in ticks and rodents in Zhejiang, south-east China
    Chen Yi Chu
    Department of Epidemiology, Beijing Institute of Microbiology and Epidemiology, State Key Laboratory of Pathogen and Biosecurity, Beijing 100071, PR China
    J Med Microbiol 57:980-5. 2008
  4. ncbi request reprint Molecular detection of spotted fever group Rickettsia in Dermacentor silvarum from a forest area of northeastern China
    Wu Chun Cao
    Beijing Institute of Microbiology and Epidemiology, State Key Laboratory of Pathogen and Biosecurity, 20 Dong Da St, Fengtai District, Beijing 100071, People s Republic of China
    J Med Entomol 45:741-4. 2008
  5. pmc Detection of Francisella tularensis in ticks and identification of their genotypes using multiple-locus variable-number tandem repeat analysis
    Fang Zhang
    Beijing Institute of Microbiology and Epidemiology, State Key Lab of Pathogen and Biosecurity, 20 Dong Da Jie Street, Fengtai District, Beijing 100071, PR China
    BMC Microbiol 8:152. 2008
  6. pmc Geo-spatial hotspots of hemorrhagic fever with renal syndrome and genetic characterization of Seoul variants in Beijing, China
    Shu Qing Zuo
    State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China
    PLoS Negl Trop Dis 5:e945. 2011
  7. pmc Landscape elements and Hantaan virus-related hemorrhagic fever with renal syndrome, People's Republic of China
    Lei Yan
    State Key Laboratory of Remote Sensing Science, IRSA CAS, Beijing, People s Republic of China
    Emerg Infect Dis 13:1301-6. 2007
  8. pmc Molecular epidemiology of SARS-associated coronavirus, Beijing
    Wei Liu
    Beijing Institute of Microbiology and Epidemiology, Beijing, People s Republic of China
    Emerg Infect Dis 11:1420-4. 2005
  9. pmc Spatiotemporal trends and climatic factors of hemorrhagic fever with renal syndrome epidemic in Shandong Province, China
    Li Qun Fang
    State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China
    PLoS Negl Trop Dis 4:e789. 2010
  10. pmc Spatiotemporal dynamics of hemorrhagic fever with renal syndrome, Beijing, People's Republic of China
    Li Qun Fang
    State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing 100071, People s Republic of China
    Emerg Infect Dis 15:2043-5. 2009

Collaborators

Detail Information

Publications99

  1. ncbi request reprint Prevalence of Anaplasma phagocytophila and Borrelia burgdorferi in Ixodes persulcatus ticks from northeastern China
    Wu Chun Cao
    Department of Epidemiology, Beijing Institute of Microbiology and Epidemiology, Fengtai District, Beijing, People s Republic of China
    Am J Trop Med Hyg 68:547-50. 2003
    ....
  2. ncbi request reprint A new Hantaan-like virus in rodents (Apodemus peninsulae) from Northeastern China
    Jia Fu Jiang
    Beijing Institute of Microbiology and Epidemiology, State Key Laboratory of Pathogen and Biosecurity, Beijing 100071, PR China
    Virus Res 130:292-5. 2007
    ..These findings imply that hantavirus Jililn-AP06 strain from A. peninsulae is a new record of rodent-borne AMR virus in China. A. peninsulae might be a natural carrier of two distinct hantaviruses, AMR virus and HTNV in China...
  3. doi request reprint Presence of pathogenic Borrelia burgdorferi sensu lato in ticks and rodents in Zhejiang, south-east China
    Chen Yi Chu
    Department of Epidemiology, Beijing Institute of Microbiology and Epidemiology, State Key Laboratory of Pathogen and Biosecurity, Beijing 100071, PR China
    J Med Microbiol 57:980-5. 2008
    ..garinii and one (2 %) was infected with B. afzelii. Twelve (75 %) of the positive rodents were infected with B. garinii and four (25 %) were infected with the Borrelia spirochaete belonging to B. valaisiana-related group...
  4. ncbi request reprint Molecular detection of spotted fever group Rickettsia in Dermacentor silvarum from a forest area of northeastern China
    Wu Chun Cao
    Beijing Institute of Microbiology and Epidemiology, State Key Laboratory of Pathogen and Biosecurity, 20 Dong Da St, Fengtai District, Beijing 100071, People s Republic of China
    J Med Entomol 45:741-4. 2008
    ..sibirica and discovered a novel rickettsial agent in this area, the sequence of which was identical to that of DnS14 genotype Rickettsia previously reported in the former Soviet Union...
  5. pmc Detection of Francisella tularensis in ticks and identification of their genotypes using multiple-locus variable-number tandem repeat analysis
    Fang Zhang
    Beijing Institute of Microbiology and Epidemiology, State Key Lab of Pathogen and Biosecurity, 20 Dong Da Jie Street, Fengtai District, Beijing 100071, PR China
    BMC Microbiol 8:152. 2008
    ....
  6. pmc Geo-spatial hotspots of hemorrhagic fever with renal syndrome and genetic characterization of Seoul variants in Beijing, China
    Shu Qing Zuo
    State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China
    PLoS Negl Trop Dis 5:e945. 2011
    ..Beijing metropolis is a novel affected region, where the HFRS incidence seems to be diverse from place to place...
  7. pmc Landscape elements and Hantaan virus-related hemorrhagic fever with renal syndrome, People's Republic of China
    Lei Yan
    State Key Laboratory of Remote Sensing Science, IRSA CAS, Beijing, People s Republic of China
    Emerg Infect Dis 13:1301-6. 2007
    ..These findings have important applications for targeting HFRS interventions in mainland China...
  8. pmc Molecular epidemiology of SARS-associated coronavirus, Beijing
    Wei Liu
    Beijing Institute of Microbiology and Epidemiology, Beijing, People s Republic of China
    Emerg Infect Dis 11:1420-4. 2005
    ..The same series of mutations occurring in separate geographic locations and at different times suggests a dominant process of viral adaptation to the host...
  9. pmc Spatiotemporal trends and climatic factors of hemorrhagic fever with renal syndrome epidemic in Shandong Province, China
    Li Qun Fang
    State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China
    PLoS Negl Trop Dis 4:e789. 2010
    ..Since then, the disease has spread across the province, and as of 2005, all 111 counties were reported to have local human infections. However, causes underlying such rapid spread and wide distribution remain less well understood...
  10. pmc Spatiotemporal dynamics of hemorrhagic fever with renal syndrome, Beijing, People's Republic of China
    Li Qun Fang
    State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing 100071, People s Republic of China
    Emerg Infect Dis 15:2043-5. 2009
    ..The seasonal variation in its incidence was observed by creating an epidemic curve. HFRS was associated with developed land, orchards, and rice paddies...
  11. pmc Long-term SARS coronavirus excretion from patient cohort, China
    Wei Liu
    Beijing Institute of Microbiology and Epidemiology, Beijing, People s Republic of China
    Emerg Infect Dis 10:1841-3. 2004
    ..The median (range) duration of virus excretion in sputa and stools was 21 (14-52) and 27 (16-126) days, respectively. Coexisting illness or conditions were associated with longer viral excretion in stools...
  12. pmc Human infection with Candidatus Neoehrlichia mikurensis, China
    Hao Li
    Beijing Institute of Microbiology and Epidemiology, Beijing, People s Republic of China
    Emerg Infect Dis 18:1636-9. 2012
    ..We identified in 7 infected patients and natural foci for this bacterium. Field surveys showed that 1.6% of ticks and 3.8% of rodents collected from residences of patients were also infected...
  13. pmc Distribution and risk factors of 2009 pandemic influenza A (H1N1) in mainland China
    Li Qun Fang
    State Key Laboratory of Pathogens and Biosecurity, Beijing Institute of Microbiology and Epidemiology, People s Republic of China
    Am J Epidemiol 175:890-7. 2012
    ..These findings indicate that interventions focused on domestic travel, population density, and climatic factors could play a role in mitigating the public health impact of future influenza pandemics...
  14. pmc Anaplasma phagocytophilum Infection in Ticks, China-Russia Border
    Jia Fu Jiang
    State Key Laboratory of Pathogen and Biosecurity, Beijing, People s Republic of China and Institute of Microbiology and Epidemiology, Beijing
    Emerg Infect Dis 17:932-4. 2011
    ..The objectives of this study were to investigate the prevalence of A. phagocytophilum in ticks collected from the China-Russia border and to characterize the agent by molecular biology techniques...
  15. pmc Anaplasma phagocytophilum from Rodents and Sheep, China
    Lin Zhan
    Beijing Institute of Microbiology and Epidemiology, Beijing, People s Republic of China
    Emerg Infect Dis 16:764-8. 2010
    ..The multiple sequences of the 3 isolates were identical to each other but different from all known strains from other countries. The public health and veterinary relevance of the isolates deserves further investigation...
  16. pmc Francisella tularensis in rodents, China
    Fang Zhang
    Beijing Institute of Microbiology and Epidemiology, Beijing, People s Republic of China
    Emerg Infect Dis 12:994-6. 2006
    ..76% in total, and 11.65%, 10.00%, 6.56%, 1.77%, and 0% in Jilin, Xinjiang, Heilongjiang, Inner Mongolia, and Zhejiang, respectively. Sequence analysis showed that all the detected agents belonged to F. tularensis subsp. holarctica...
  17. pmc Orientia tsutsugamushi in eschars from scrub typhus patients
    Yun Xi Liu
    Beijing Institute of Microbiology and Epidemiology, Beijing, People s Republic of China
    Emerg Infect Dis 12:1109-12. 2006
    ..The findings indicate that patients' eschars can be used for detection and genetic characterization of O. tsutsugamushi during the convalescent phase...
  18. pmc Pulmonary tuberculosis and SARS, China
    Wei Liu
    Emerg Infect Dis 12:707-9. 2006
  19. pmc Climate variability and hemorrhagic fever with renal syndrome transmission in Northeastern China
    Wen Yi Zhang
    Beijing Institute of Microbiology and Epidemiology, China
    Environ Health Perspect 118:915-20. 2010
    ..The transmission of hemorrhagic fever with renal syndrome (HFRS) is influenced by climatic variables. However, few studies have examined the quantitative relationship between climate variation and HFRS transmission...
  20. pmc Environmental factors contributing to the spread of H5N1 avian influenza in mainland China
    Li Qun Fang
    Beijing Institute of Microbiology and Epidemiology, State Key Laboratory of Pathogen and Biosecurity, Beijing, People s Republic of China
    PLoS ONE 3:e2268. 2008
    ..The unrestrained worldwide spread of this disease has caused great anxiety about the potential of another global pandemic. However, the effect of environmental factors influencing the spread of HPAI H5N1 virus is unclear...
  21. pmc IL-12 RB1 genetic variants contribute to human susceptibility to severe acute respiratory syndrome infection among Chinese
    Fang Tang
    Beijing Institute of Microbiology and Epidemiology, Beijing, People s Republic of China
    PLoS ONE 3:e2183. 2008
    ..Cytokines play important roles in antiviral action. We examined whether polymorphisms of interleukin (IL)-12 receptor B1 (IL-12RB1) affect the susceptibility to and outcome of severe acute respiratory syndrome (SARS)...
  22. pmc Tick-borne agents in rodents, China, 2004-2006
    Lin Zhan
    Beijing Institute of Microbiology and Epidemiology, Beijing, People s Republic of China
    Emerg Infect Dis 15:1904-8. 2009
    ..These findings demonstrate that these tick-borne agents cocirculate and that a variety of rodent species may be involved in their enzootic maintenance...
  23. pmc Mapping spread and risk of avian influenza A (H7N9) in China
    Li Qun Fang
    The State Key laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing 100071, P R China
    Sci Rep 3:2722. 2013
    ..These findings could be used to inform targeted surveillance and control efforts in both human and animal populations to reduce the risk of future human infections. ..
  24. pmc Dual seasonal patterns for influenza, china
    Yue Long Shu
    Chinese Center for Disease Control and Prevention, Beijing, People s Republic of China Y L Shu, Y Gao Beijing Institute of Microbiology and Epidemiology, Beijing L Q Fang University Medical Center Rotterdam, Rotterdam, the Netherlands S J de Vlas, J H Richardus and State Key Laboratory of Pathogen and Biosecurity, Beijing W C Cao
    Emerg Infect Dis 16:725-6. 2010
    ..We emphasize the spread of influenza from southern to northern China...
  25. pmc Circulation of Coxsackievirus A10 and A6 in hand-foot-mouth disease in China, 2009-2011
    Qing Bin Lu
    Department of Epidemiology and Health Statistics, Shandong University, Jinan, People s Republic of China
    PLoS ONE 7:e52073. 2012
    ..CV-A10 and CV-A6 were co-circulating together with EV-71 and CV-A16 in recent years. CV-A10 infection might also be independently associated with severe HFMD...
  26. pmc Human brucellosis, inner mongolia, china
    Wen Yi Zhang
    People s Liberation Army Institute of Disease Control and Prevention, Beijing, People s Republic of China W Y Zhang, H L Sun, S L Li Beijing Institute of Microbiology and Epidemiology, Beijing W Y Zhang, J F Jiang, W Liu, W C Cao Inner Mongolia Center for Disease Control and Prevention, Hohhot, People s Republic of China W D Guo and Chinese Center for Disease Control and Prevention, Beijing S H Sun
    Emerg Infect Dis 16:2001-3. 2010
    ..National and local public health authorities are concerned about the increasing incidence of the disease in this province. Here we report the epidemic characteristics that existed in this region during 1999-2008...
  27. doi request reprint An efficient strategy of screening for pathogens in wild-caught ticks and mosquitoes by reusing small RNA deep sequencing data
    Lu Zhuang
    State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Fengtai District, Beijing, P R China
    PLoS ONE 9:e90831. 2014
    ..Our study demonstrated the reuse of sRNA deep sequencing data would have the potential to trace the origin of pathogens or discover novel agents of emerging/re-emerging infectious diseases...
  28. pmc Spatiotemporal distribution of malaria and the association between its epidemic and climate factors in Hainan, China
    Dan Xiao
    Department of Epidemiology, Faculty of Preventive Medicine, Fourth Military Medical University, Xi an, China
    Malar J 9:185. 2010
    ..This study detected the spatiotemporal distribution of malaria and explored the association between malaria epidemics and climate factors in Hainan...
  29. pmc Spatial analysis of malaria in Anhui province, China
    Wenyi Zhang
    Beijing Institute of Microbiology and Epidemiology, State Key Laboratory of Pathogen and Biosecurity, Beijing, PR China
    Malar J 7:206. 2008
    ..It is necessary to understand the spatial distribution of malaria cases and to identify highly endemic areas for future public health planning and resource allocation in Anhui Province...
  30. pmc Association of SARS susceptibility with single nucleic acid polymorphisms of OAS1 and MxA genes: a case-control study
    Jing He
    Beijing Institute of Microbiology and Epidemiology, State Key Laboratory of Pathogen and Biosecurity, Beijing, China
    BMC Infect Dis 6:106. 2006
    ....
  31. pmc Spatial analysis of hemorrhagic fever with renal syndrome in China
    Liqun Fang
    Beijing Institute of Microbiology and Epidemiology, State Key Laboratory of Pathogen and Biosecurity, Beijing, China
    BMC Infect Dis 6:77. 2006
    ..In this study, we conducted a geographic information system (GIS)-based spatial analysis on distribution of HFRS cases for the whole country with an objective to inform priority areas for public health planning and resource allocation...
  32. pmc Clinical characteristics of the autumn-winter type scrub typhus cases in south of Shandong province, northern China
    Yun Xi Liu
    Department of Nosocomial Infection Management and Disease Control, Institute of Hospital Management, Chinese People s Liberation Army General Hospital, Beijing, PR China
    BMC Infect Dis 9:82. 2009
    ..This newly recognized scrub typhus was subsequently reported in many areas of northern China and was then called "autumn-winter type". However, clinical characteristics of associated cases have not been reported...
  33. pmc Granulocytic Ehrlichiae in Ixodes persulcatus ticks from an area in China where Lyme disease is endemic
    W C Cao
    Institute of Microbiology and Epidemiology, Fengtai District, Beijing 100071, China
    J Clin Microbiol 38:4208-10. 2000
    ..This is the first identification of granulocytic ehrlichiae in ticks in Asia and the first report of infection in I. persulcatus anywhere...
  34. ncbi request reprint Natural Anaplasma phagocytophilum infection of ticks and rodents from a forest area of Jilin Province, China
    Wu Chun Cao
    Beijing Institute of Microbiology and Epidemiology, State Key Laboratory of Pathogen and Biosecurity, Beijing, People s Republic of China
    Am J Trop Med Hyg 75:664-8. 2006
    ..phagocytophilum agents. These findings add new information on the ecologic features of A. phagocytophilum and indicate the threat of anaplasmosis in the area...
  35. pmc Identification of Ehrlichia chaffeensis by nested PCR in ticks from Southern China
    W C Cao
    Institute of Microbiology and Epidemiology, Beijing 100071, China
    J Clin Microbiol 38:2778-80. 2000
    ..7%) of 240 adult and at least 4.2% of 215 nymphal (pooled specimens) Haemaphysalis yeni ticks tested positive. Four other species of ticks were negative. Selected positive amplicons were confirmed by DNA sequencing...
  36. ncbi request reprint [Study on the coinfection of three tick-borne infectious diseases in China using polymerase chain reaction method]
    Qiu Min Zhao
    Institute of Microbiology and Epidemiology, Academy of Military Medical Science, Beijing 100071, China
    Zhonghua Liu Xing Bing Xue Za Zhi 26:9-13. 2005
    ..To study the existence of Ehrluichiosis, lyme disease and tick-borne spotted fever coinfection in some areas in China...
  37. ncbi request reprint Prevalence and genetic diversities of hantaviruses in rodents in Beijing, China
    Jia Fu Jiang
    Beijing Institute of Microbiology and Epidemiology, State Key Laboratory of Pathogen and Biosecurity, 20 Dong Da Jie Street, Fengtai, Beijing, China
    Am J Trop Med Hyg 78:98-105. 2008
    ..A strain detected from a trading center of agricultural products, which might be imported from other provinces, was genetically different from other strains of Beijing...
  38. doi request reprint Genetic analysis of a hantavirus strain carried by Niviventer confucianus in Yunnan province, China
    Zhi Wei Cao
    State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, 20 Dongda Street, Fengtai District, Beijing 100071, China
    Virus Res 153:157-60. 2010
    ..These data suggest that strain YN509 is a new subtype of DBSV, which appears to be widely distributed in China with a higher genetic diversity than expected...
  39. ncbi request reprint [Study on the correlation between positive rates of SARS RNA in clinical confirmed SARS patients and the appearance of RNA in relation to the development of the disease]
    Fang Tang
    Institute of Microbiology and Epidemiology, Beijing 100071, China
    Zhonghua Liu Xing Bing Xue Za Zhi 25:120-3. 2004
    ....
  40. ncbi request reprint [A case-control study on the vitamin D receptor gene polymorphisms and susceptibility to pulmonary tuberculosis]
    Wei Liu
    Epidemiological Department of Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing 100071, China
    Zhonghua Liu Xing Bing Xue Za Zhi 24:389-92. 2003
    ..To investigate the association between the genetic polymorphisms of VDR gene and susceptibility to pulmonary tuberculosis...
  41. ncbi request reprint Seoul virus in patients and rodents from Beijing, China
    Shu Qing Zuo
    Beijing Institute of Microbiology and Epidemiology, State Key Laboratory of Pathogen and Biosecurity, Beijing, China
    Am J Trop Med Hyg 78:833-7. 2008
    ..7% for one of the cases of HFRS--the human- and Rattus norvegicus-originated SEOV sequences--had only two silent substitutions, suggesting genetic analysis is an essential tool for "case-investigation."..
  42. doi request reprint A newly discovered Anaplasma phagocytophilum variant in rodents from southeastern China
    Lin Zhan
    Beijing Institute of Microbiology, and Epidemiology, State Key Laboratory of Pathogen and Biosecurity, 20 Dong Da Street, Fengtai District, Beijing 100071, PR China
    Vector Borne Zoonotic Dis 8:369-80. 2008
    ..phagocytophilum sequences,as were msp4 and groESL. These findings indicate that the newly discovered agent represents a novel A. phagocytophilum variant...
  43. doi request reprint Anaplasma phagocytophilum in livestock and small rodents
    Lin Zhan
    State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, 20 Dong Da Street, Fengtai District, Beijing 100071, People s Republic of China
    Vet Microbiol 144:405-8. 2010
    ..phagocytophilum in rodents might be able to infect livestock and intensified the threats of anaplasmosis to livestock in the area. Further studies on public health significance of the agent are worth investigation in future...
  44. pmc Using geographic information system-based ecologic niche models to forecast the risk of hantavirus infection in Shandong Province, China
    Lan Wei
    State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, People s Republic of China
    Am J Trop Med Hyg 84:497-503. 2011
    ..These findings have the applications for targeting control and prevention efforts...
  45. ncbi request reprint Predicting the risk of hantavirus infection in Beijing, People's Republic of China
    Wen Yi Zhang
    Beijing Institute of Microbiology and Epidemiology, Beijing, People s Republic of China
    Am J Trop Med Hyg 80:678-83. 2009
    ..12, 95% CI = 1.02-5.96), and moderate elevation (OR = 9.83, 95% CI = 2.22-43.55). A risk map was constructed on the basis of these significant factors to predict extension and transmission of infection with hantavirus in this region...
  46. ncbi request reprint Two-year prospective study of the humoral immune response of patients with severe acute respiratory syndrome
    Wei Liu
    Beijing Institute of Microbiology and Epidemiology, State Key Laboratory of Pathogen and Biosecurity, Beijing, People s Republic of China
    J Infect Dis 193:792-5. 2006
    ..8% of patients at month 24. The finding that NAbs remained detectable throughout follow-up is reassuring in terms of protection provided against reinfection; however, NAb titers decreased markedly after month 16...
  47. ncbi request reprint [Study on the molecular epidemiology of hantaviruse carried by hosts in northern suburb of Beijing]
    Shu Qing Zuo
    Beijing Institute of Microbiology and Epidemiology, Beijing 100071, China
    Zhonghua Liu Xing Bing Xue Za Zhi 25:421-4. 2004
    ..To investigate hantanvirus infection of captured rodents in Haidian district and Changping district of Beijing and to type hantavirus using molecular technique...
  48. ncbi request reprint [Identification of Amur like virus in Apodemus peninsulae and its molecular characteristics in China]
    Wen Yi Zhang
    State Key Laboratory of Pathogen and Biosecurity, Institute of Microbiology and Epidemiology, Beijing 100071, China
    Zhonghua Liu Xing Bing Xue Za Zhi 28:482-6. 2007
    ..To confirm the existence of Amur-like viruses in Apodemus peninsulae in China, and to understand the molecular characteristics of these viruses...
  49. ncbi request reprint [Using geographic information system to study on the association between epidemic areas and main animal hosts of hemorrhagic fever with renal syndrome in China]
    Li Qun Fang
    Beijing Institute of Microbiology and Epidemiology, Beijing 100071, China
    Zhonghua Liu Xing Bing Xue Za Zhi 25:929-33. 2004
    ..To analyze the association between types of epidemic areas and proportion of main animal hosts of hemorrhagic fever with renal syndrome (HFRS) in China...
  50. doi request reprint Anaplasma phagocytophilum and Borrelia burgdorferi in rabbits from southeastern China
    Lin Zhan
    Beijing Institute of Microbiology and Epidemiology, Beijing 100071, People s Republic of China
    Vet Parasitol 162:354-6. 2009
    ..phagocytophilum and a B. garinii genotype. This is the first detection of the two tick-borne agents in Chinese rabbits, the role of which in the maintenance of the agents deserve further investigations...
  51. ncbi request reprint [Study on the application of geographic information system in spatial distribution of hemorrhage fever with renal syndrome in China]
    Li Qun Fang
    Institute of Microbiology and Epidemiology, Academy of Military Medical Science, Beijing 100071, China
    Zhonghua Liu Xing Bing Xue Za Zhi 24:265-8. 2003
    ..To analyze the spatial distribution of hemorrhagic fever with renal syndrome (HFRS) in China by geographic information system, and to draw up a map on HRFS risk areas...
  52. ncbi request reprint Genetic diversity of Borrelia burgdorferi sensu lato isolates from Northeastern China
    Chen Yi Chu
    State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, PR China
    Vector Borne Zoonotic Dis 11:877-82. 2011
    ..These findings demonstrate the genetic diversity of B. burgdorferi sensu lato isolates from northeastern China...
  53. ncbi request reprint [A case-control study on natural-resistance-associated macrophage protein 1 gene polymorphisms and susceptibility to pulmonary tuberculosis]
    Wei Liu
    Beijing Institute of Microbiology and Epidemiology, Beijing 100071, China
    Zhonghua Yu Fang Yi Xue Za Zhi 37:408-11. 2003
    ..To investigate association between the natural-resistance-associated macrophage protein 1 (NRAMP1) gene polymorphisms and susceptibility to pulmonary tuberculosis (TB) in Chinese Han population...
  54. ncbi request reprint [Investigation on Anaplasma phagocytophilum infection in rodents from forest areas in northeastern China]
    Lin Zhan
    State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing 100071, China
    Zhonghua Liu Xing Bing Xue Za Zhi 28:157-9. 2007
    ..To investigate the prevalence of Anaplasma phagocytophilum in rodents from forest areas in northeastern China...
  55. doi request reprint Mixed infections of pandemic H1N1 and seasonal H3N2 viruses in 1 outbreak
    Wei Liu
    Beijing Institute of Microbiology and Epidemiology, State Key Laboratory of Pathogen and Biosecurity, Beijing, China
    Clin Infect Dis 50:1359-65. 2010
    ..In early September 2009, an outbreak of influenza occurred at a college campus in Beijing, China, in which both pandemic H1N1 and seasonal H3N2 viruses were detected...
  56. doi request reprint Lack of peripheral memory B cell responses in recovered patients with severe acute respiratory syndrome: a six-year follow-up study
    Fang Tang
    State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing 100071, People s Republic of China
    J Immunol 186:7264-8. 2011
    ..In contrast, specific T cell anamnestic responses can be maintained for at least 6 y. These findings have applications in preparation for the possible reemergence of SARS...
  57. ncbi request reprint [A case-control study on the mxA polymorphisms and susceptibility to severe acute respiratory syndromes]
    Hong Wei Wang
    Epidemiological Department of Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing 100071, China
    Zhonghua Liu Xing Bing Xue Za Zhi 26:574-7. 2005
    ..To investigate the association between the genetic polymorphisms of myxovirus resistance 1 (MxA) gene and susceptibility to severe acute respiratory syndromes (SARS)...
  58. ncbi request reprint Key differentiating features between scrub typhus and hemorrhagic fever with renal syndrome in northern China
    Yun Xi Liu
    Beijing Institute of Microbiology and Epidemiology, State Key Laboratory of Pathogen and Biosecurity, Beijing, People s Republic of China
    Am J Trop Med Hyg 76:801-5. 2007
    ..In addition, platelet counts in patients with HFRS were significantly lower than in patients with scrub typhus. These findings will be useful for physicians to distinguish scrub typhus from HFRS...
  59. ncbi request reprint Lower cellular immune responses to influenza A (H3N2) in the elderly
    Na Jia
    Beijing Institute of Microbiology and Epidemiology, China
    J Med Virol 81:1471-6. 2009
    ..Measurement of the ex vivo cellular immune responses to influenza should be incorporated into the evaluation of protective immunity in elderly persons...
  60. ncbi request reprint [The application of indirect immuno-fluorescence assay in the diagnosis of severe acute respiratory syndrome]
    Li Qun Fang
    Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing 100071, China
    Zhonghua Liu Xing Bing Xue Za Zhi 24:484-6. 2003
    ..To explore the temporal profile of serum antibody against coronavirus in patients with severe acute respiratory syndrome (SARS), and to evaluate the reliability of indirect immuno-fluorescence assay (IFA) in the diagnosis of SARS...
  61. pmc Novel genospecies of Borrelia burgdorferi sensu lato from rodents and ticks in southwestern China
    Chen Yi Chu
    Beijing Institute of Microbiology and Epidemiology, State Key Laboratory of Pathogen and Biosecurity, Beijing 100071, People s Republic of China
    J Clin Microbiol 46:3130-3. 2008
    ..burgdorferi sensu lato rather than B. valaisiana. The finding explained the differences in transmission cycle and phenotype between B. valaisiana strains from Europe and B. valaisiana-related strains from eastern Asia...
  62. doi request reprint Increased thyroid function and elevated thyroid autoantibodies in pediatric patients with moyamoya disease: a case-control study
    Hao Li
    Beijing Institute of Microbiology and Epidemiology, State Key Laboratory of Pathogen and Biosecurity, Beijing, China
    Stroke 42:1138-9. 2011
    ..The purpose of this study was to investigate whether thyroid function and thyroid autoantibodies were associated with the risk of moyamoya disease in pediatric subjects...
  63. ncbi request reprint The SARS epidemic in mainland China: bringing together all epidemiological data
    Dan Feng
    Beijing Institute of Microbiology and Epidemiology, State Key Laboratory of Pathogen and Biosecurity, Beijing, P R China
    Trop Med Int Health 14:4-13. 2009
    ..To document and verify the number of cases of severe acute respiratory syndrome (SARS) during the 2002-2003 epidemic in mainland China...
  64. ncbi request reprint Serological reports of human infections of H7 and H9 avian influenza viruses in northern China
    Na Jia
    Beijing Institute of Microbiology and Epidemiology, Fengtai District, Beijing, PR China
    J Clin Virol 44:225-9. 2009
    ..H7 and H9 subtype avian influenza viruses pose a similar threat to humans as H5 virus...
  65. ncbi request reprint [Spatial analysis on the distribution of hemorrhagic fever with renal syndrome by geographic information system in Haidian district, Beijing]
    Li Qun Fang
    Institute of Microbiology and Epidemiology, Academy of Military Medical Science, Beijing 100071, China
    Zhonghua Liu Xing Bing Xue Za Zhi 24:1020-3. 2003
    ..To analyze the spatial distribution of hemorrhagic fever with renal syndrome (HFRS) in Haidian district, Beijing and to explore the geographical characteristics of HFRS in highly endemic areas...
  66. ncbi request reprint Failure of Japanese encephalitis vaccine and infection in inducing neutralizing antibodies against West Nile virus, People's Republic of China
    Fang Tang
    Beijing Institute of Microbiology and Epidemiology, State Key Laboratory of Pathogen and Biosecurity, Beijing, People s Republic of China
    Am J Trop Med Hyg 78:999-1001. 2008
    ....
  67. ncbi request reprint [A case-control study on the risk factors of severe acute respiratory syndromes among health care workers]
    Huai jian Ma
    Institute of Microbiology and Epidemiology, Beijing 100071, China
    Zhonghua Liu Xing Bing Xue Za Zhi 25:741-4. 2004
    ..To study the factors in relation to severe acute respiratory syndromes (SARS) among health care workers and to develop related protective measures...
  68. ncbi request reprint Geographical spread of SARS in mainland China
    Li Qun Fang
    Beijing Institute of Microbiology and Epidemiology, State Key Laboratory of Pathogen and Biosecurity, Beijing, P R China
    Trop Med Int Health 14:14-20. 2009
    ..To describe the spatiotemporal diffusion of the severe acute respiratory syndrome (SARS) epidemic in mainland China, and to analyse the spatial pattern of SARS transmission from the Beijing epicentre to its neighbouring areas...
  69. doi request reprint Clinical and immunological characteristics of patients with 2009 pandemic influenza A (H1N1) virus infection after vaccination
    Wei Liu
    Beijing Institute of Microbiology and Epidemiology, State Key Laboratory of Pathogen and Biosecurity, Beijing, People s Republic of China
    Clin Infect Dis 51:1028-32. 2010
    ..We followed a cohort of 773 individuals who received a monovalent vaccine against 2009 pandemic influenza A (H1N1). Approximately 6 weeks after vaccination, 12 persons developed the disease...
  70. ncbi request reprint [A new type of spotted fever group Rickttsiaes detected in the area of Changbai mountain, Jilin province]
    Yong jian Hao
    The Preventive Team of People s Liberation Army Second Artillery, Beijing 100071, China
    Zhonghua Liu Xing Bing Xue Za Zhi 24:1126-8. 2003
    ..In order to find out the current situation of tick-borne spotted fever in the area of Changbai mountain, Jilin province...
  71. ncbi request reprint [Typing of hemorrhagic fever with renal syndrome by cluster analysis]
    Xiu Hua Guo
    Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing 100071, China
    Zhonghua Liu Xing Bing Xue Za Zhi 24:577-80. 2003
    ..To make an inquiry into method of typing of hemorrhagic fever with renal syndrome (HFRS)...
  72. doi request reprint Characteristics of pediatric scrub typhus in a new endemic region of northern China
    Yun Xi Liu
    Chinese People s Liberation Army General Hospital, Department of Hospital Infection Control, Beijing, People s Republic of China
    Pediatr Infect Dis J 28:1111-4. 2009
    ..Scrub typhus emerged in northern China in 1986. Our objective was to document epidemiologic, clinical and laboratory features of pediatric scrub typhus in this new endemic area...
  73. ncbi request reprint Case fatality of SARS in mainland China and associated risk factors
    Na Jia
    Beijing Institute of Microbiology and Epidemiology, State Key Laboratory of Pathogen and Biosecurity, Beijing, P R China
    Trop Med Int Health 14:21-7. 2009
    ..To analyse the case fatality ratio (CFR) and its risk factors for severe acute respiratory syndrome (SARS) in mainland China by using a comprehensive dataset of all probable cases...
  74. pmc Change in rainfall drives malaria re-emergence in Anhui Province, China
    Hong wei Gao
    State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, People s Republic of China
    PLoS ONE 7:e43686. 2012
    ..Malaria epidemics showed a high spatial heterogeneity in Anhui Province during the 1990-2009 study periods. The change in rainfall drives the reemergence of malaria in the northern Anhui Province...
  75. ncbi request reprint Duration of symptom onset to hospital admission and admission to discharge or death in SARS in mainland China: a descriptive study
    Dan Feng
    Beijing Institute of Microbiology and Epidemiology, State Key Laboratory of Pathogen and Biosecurity, Beijing, P R China
    Trop Med Int Health 14:28-35. 2009
    ....
  76. ncbi request reprint No evidence of over-reporting of SARS in mainland China
    Wei Liu
    Beijing Institute of Microbiology and Epidemiology, State Key Laboratory of Pathogen and Biosecurity, Beijing, P R China
    Trop Med Int Health 14:46-51. 2009
    ..To find out whether there was over-reporting of SARS patients in mainland China in view of the relatively low case fatality ratio in mainland China, in comparison with other affected countries and areas...
  77. pmc Identification of norovirus as the top enteric viruses detected in adult cases with acute gastroenteritis
    Li Juan Liu
    Department of Epidemiology, Beijing Institute of Microbiology and Epidemiology, State Key Laboratory of Pathogen and Biosecurity, Beijing, People s Republic of China
    Am J Trop Med Hyg 82:717-22. 2010
    ....
  78. doi request reprint Association of a functional polymorphism in the MMP-3 gene with Moyamoya Disease in the Chinese Han population
    Hao Li
    Beijing Institute of Microbiology and Epidemiology, State Key Laboratory of Pathogen and Biosecurity, Beijing, PR China
    Cerebrovasc Dis 30:618-25. 2010
    ..The study was designed to examine the association of single nucleotide polymorphisms in matrix metalloproteinase (MMP) and tissue inhibitors of metalloproteinase (TIMP) genes with MMD occurrence...
  79. ncbi request reprint Soochong virus and Amur virus might be the same entities of hantavirus
    Jia Fu Jiang
    State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, People s Republic of China
    J Med Virol 79:1792-5. 2007
    ..Although two genetic sublineages of SOOV exist, these findings revealed that AMRV and SOOV might belong to the same entities of hantavirus...
  80. pmc Genome sequence of Borrelia afzelii Strain HLJ01, isolated from a patient in China
    Bao Gui Jiang
    State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, People s Republic of China
    J Bacteriol 194:7014-5. 2012
    ..We report here the genome sequence of Borrelia afzelii strain HLJ01, isolated from a patient with Lyme disease in China. It is the first report of the whole genome of a B. burgdorferi sensu lato isolate from a human in China...
  81. doi request reprint Host immune response to A(H1N1)pdm09 vaccination and infection: a one-year prospective study on six cohorts of subjects
    Wei Liu
    State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing 100071, PR China
    Vaccine 30:4785-9. 2012
    ..The long-term immunogenicity after novel vaccine against A(H1N1)pdm09 administration or natural infection has not been well investigated...
  82. doi request reprint Seroprevalence and genetic characteristics of five subtypes of influenza A viruses in the Chinese pig population: a pooled data analysis
    Wei Liu
    Beijing Institute of Microbiology and Epidemiology, State Key Laboratory of Pathogen and Biosecurity, 100071 Beijing, PR China
    Vet J 187:200-6. 2011
    ..It was concluded from both serological and genetic studies that subtypes H1, H3, H5 and H9 are currently co-circulating in pigs in China, with the H1 subtype most commonly detected, followed by H3...
  83. pmc Decision support system for the response to infectious disease emergencies based on WebGIS and mobile services in China
    Ya Pin Li
    State Key Laboratory of Pathogens and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, People s Republic of China
    PLoS ONE 8:e54842. 2013
    ..Therefore, it is necessary to have an unobstructed channel and convenient tool for the collection and analysis of epidemiologic information in the field...
  84. doi request reprint Dual infection with Anaplasma phagocytophilum and Babesia microti in a Rattus norvegicus, China
    Xiao Guang Zhao
    State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, People s Republic of China
    Ticks Tick Borne Dis 4:399-402. 2013
    ..Their molecular biological characteristics were described. The public health and veterinary significance of the dual infection of the 2 tick-borne agents deserve further investigation. ..
  85. pmc Genetic variants in MARCO are associated with the susceptibility to pulmonary tuberculosis in Chinese Han population
    Mai Juan Ma
    State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, People s Republic of China
    PLoS ONE 6:e24069. 2011
    ..Macrophage receptor with a collagenous structure (MARCO) is essential components required for toll like receptor-signaling in macrophage response to Mycobacterium tuberculosis, which may contribute to tuberculosis risk...
  86. ncbi request reprint Mathematical modelling of SARS and other infectious diseases in China: a review
    Xiao Na Han
    Beijing Institute of Microbiology and Epidemiology, State Key Laboratory of Pathogen and Biosecurity, Beijing, P R China
    Trop Med Int Health 14:92-100. 2009
    ..To give an overview of the recent history of publications on mathematical modelling of infectious diseases in the Chinese literature, and a more detailed review of the models on severe acute respiratory syndrome (SARS)...
  87. doi request reprint Toll-like receptors, tumor necrosis factor-α, and interleukin-10 gene polymorphisms in risk of pulmonary tuberculosis and disease severity
    Mai Juan Ma
    Beijing Institute of Microbiology and Epidemiology, State Key Laboratory of Pathogen and Biosecurity, Beijing, China
    Hum Immunol 71:1005-10. 2010
    ..41-9.11, p = 0.007). Our results indicated that the variants in TNF-α gene were associated with susceptibility to PTB and clinical severity of disease, whereas no significance could be inferred from TLRs and IL-10 genes polymorphisms...
  88. ncbi request reprint [Design and implementation of Geographical Information System on prevention and control of cholera]
    Xiu Jun Li
    State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing 100071, China
    Zhonghua Liu Xing Bing Xue Za Zhi 33:431-4. 2012
    ..The exploitation of the software can predict and simulate the spatio-temporal risks, so as to provide guidance for the prevention and control of the disease...
  89. doi request reprint Community transmission of pandemic influenza A (H1N1) in China
    Wei Liu
    State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Fengtai District, Beijing, China
    Infect Control Hosp Epidemiol 31:961-3. 2010
    ..The genetic makeup of strains of different generations seemed to be stable. Travel in confined settings might accelerate the transmission of pandemic influenza in a community outbreak...
  90. ncbi request reprint Genomic sequence of a Japanese encephalitis virus isolate from southern China
    Jiu Song Zhang
    Beijing Institute of Microbiology and Epidemiology, People s Republic of China
    Arch Virol 154:1177-80. 2009
    ..Phylogenetic relationships based on the full-length nucleotide sequences were similar to those based on the E gene...
  91. doi request reprint Plasmodium berghei K173: selection of resistance to naphthoquine in a mouse model
    Hong Wang
    Department of Pharmacy, Beijing Institute of Microbiology and Epidemiology, State Key Laboratory of Pathogen and Biosecurity, 100071 Beijing, PR China
    Exp Parasitol 127:436-9. 2011
    ..5-fold. These findings imply NQ-resistant parasites might be selected by long-term usage of NQ in epidemic areas and the efficacy of NQ or ARCO® in chloroquine-resistant Plasmodium falciparum epidemic areas should be monitored closely...
  92. pmc Spatial analysis of tuberculosis cases in migrants and permanent residents, Beijing, 2000-2006
    Zhong Wei Jia
    Capital Medical University, Beijing, People s Republic of China
    Emerg Infect Dis 14:1413-9. 2008
    ..These findings indicate that population fluctuations have affected the rate of TB prevalence in Beijing, and interventions to control TB should include the migrant population...
  93. ncbi request reprint [Epidemiological characteristics of 420 influenza A (H1N1) cases confirmed in the early stage of the epidemic in mainland China]
    Ya Pin Li
    State Key Laboratory of Pathogen and Biosecurity, Academy of Military Medical Science Institute of Microbiology and Epidemiology, Beijing 100071, China
    Zhonghua Liu Xing Bing Xue Za Zhi 30:1102-5. 2009
    ..To describe the epidemical characteristics of A (H1N1) influenza identified in the early stage (from May 11 to June 22, 2009) of the epidemic, in mainland China...
  94. ncbi request reprint Naphthoquine phosphate and its combination with artemisinine
    Jing yan Wang
    Institute of Microbiology and Epidemiology, Academy of Malitary Medical Sciences and Epidemiology, 20 Dongdajie Fengtai, 100071, Beijing, China
    Acta Trop 89:375-81. 2004
    ..The combination tablet was initially developed by the Academy of Military Medical Sciences (AMMS), Beijing, China...
  95. ncbi request reprint Increased sensitivity for detecting avian influenza-specific antibodies by a modified hemagglutination inhibition assay using horse erythrocytes
    Na Jia
    Beijing Institute of Microbiology and Epidemiology, State Key Laboratory of Pathogen and Biosecurity, 20 Dong Da Street, Fengtai District, Beijing 100071, China
    J Virol Methods 153:43-8. 2008
    ..Based on these results, the optimized use of horse erythrocytes should be standard practice for detecting HI activities against avian influenza viruses...
  96. ncbi request reprint Spatio-temporal distribution of malaria in Yunnan Province, China
    Feng Ming Hui
    State Key Laboratory of Remote Sensing Science, Jointly Sponsored by the Institute of Remote Sensing Applications of Chinese Academy of Sciences and Beijing Normal University, Beijing, People s Republic of China
    Am J Trop Med Hyg 81:503-9. 2009
    ..These findings imply that countermeasures should target high risk areas at suitable times, when climatic factors facilitate the transmission of malaria...
  97. ncbi request reprint [Attention should be paid to understand the biological hazard and improve the ability for emergency response]
    Wu Chun Cao
    Trauma Center, 304th Hospital of People s Liberation Army, Beijing 100037, China
    Zhongguo Wei Zhong Bing Ji Jiu Yi Xue 15:327-9. 2003
  98. ncbi request reprint Fatal infection with influenza A (H5N1) virus in China
    Qing Yu Zhu
    N Engl J Med 354:2731-2. 2006