Yu xian Shen

Summary

Affiliation: Anhui Medical University
Country: China

Publications

  1. ncbi request reprint Improvement of melatonin to the learning and memory impairment induced by amyloid beta-peptide 25 - 35 in elder rats
    Y X Shen
    Institute of Clinical Pharmacology, Anhui Medical University, Hefei 230032, China
    Acta Pharmacol Sin 22:797-803. 2001
  2. ncbi request reprint In vivo evaluation of early disease progression by X-ray phase-contrast imaging in the adjuvant-induced arthritic rat
    Yongqiang Yu
    Department of Radiology, The First Affiliated Hospital of Anhui Medical University, Hefei, China
    Skeletal Radiol 35:156-64. 2006
  3. ncbi request reprint Suppressive effects of melatonin on amyloid-beta-induced glial activation in rat hippocampus
    Yuxian Shen
    Institute of Clinical Pharmacology, Anhui Medical University, Hefei, P R China
    Arch Med Res 38:284-90. 2007
  4. ncbi request reprint Melatonin reduces memory changes and neural oxidative damage in mice treated with D-galactose
    Yu xian Shen
    Institute of Clinical Pharmacology, Anhui Medical University, Hefei, China
    J Pineal Res 32:173-8. 2002
  5. ncbi request reprint Melatonin blocks rat hippocampal neuronal apoptosis induced by amyloid beta-peptide 25-35
    Yu xian Shen
    Institute of Clinical Pharmacology, Anhui Medical University, Hefei, China
    J Pineal Res 32:163-7. 2002
  6. ncbi request reprint The protective effects of melatonin from oxidative damage induced by amyloid beta-peptide 25-35 in middle-aged rats
    Y X Shen
    Institute of Clinical Pharmacology, Anhui Medical University, Hefei, China
    J Pineal Res 32:85-9. 2002
  7. ncbi request reprint Protective effects of melatonin on cortico-hippocampal neurotoxicity induced by amyloid beta-peptide 25-35
    Yu xian Shen
    Institute of Clinical Pharmacology, Anhui Medical University, Hefei 230032, China
    Acta Pharmacol Sin 23:71-6. 2002
  8. ncbi request reprint Melatonin-selenium nanoparticles protects liver against immunological injury induced by bacillus Calmette-Guerin and lipopolysaccharide
    Hua Wang
    Institute of Clinical Pharmacology, Anhui Medical University, Hefei 230032, China
    Acta Pharmacol Sin 26:745-52. 2005
  9. ncbi request reprint Protective effect of melatonin against liver injury in mice induced by Bacillus Calmette-Guerin plus lipopolysaccharide
    Hua Wang
    Institute of Clinical Pharmacology, Anhui Medical University, Hefei 230032, Anhui Province, China
    World J Gastroenterol 10:2690-6. 2004
  10. ncbi request reprint Anti-adjuvant arthritis of recombinant human endostatin in rats via inhibition of angiogenesis and proinflammatory factors
    Li Yue
    Institute of Clinical Pharmacology, Anhui Medical University, Hefei 230032, China
    Acta Pharmacol Sin 25:1182-5. 2004

Collaborators

Detail Information

Publications22

  1. ncbi request reprint Improvement of melatonin to the learning and memory impairment induced by amyloid beta-peptide 25 - 35 in elder rats
    Y X Shen
    Institute of Clinical Pharmacology, Anhui Medical University, Hefei 230032, China
    Acta Pharmacol Sin 22:797-803. 2001
    ..To investigate improvement of melatonin on learning and memory impairment induced by amyloid beta-peptide 25 - 35 (Abeta25-35) in elder rats...
  2. ncbi request reprint In vivo evaluation of early disease progression by X-ray phase-contrast imaging in the adjuvant-induced arthritic rat
    Yongqiang Yu
    Department of Radiology, The First Affiliated Hospital of Anhui Medical University, Hefei, China
    Skeletal Radiol 35:156-64. 2006
    ..To study the early change of bone matrix and soft tissue around articulation in adjuvant-induced arthritic (AIA) rats non-invasively by X-ray phase-contrast imaging (XPCI), a new imaging method...
  3. ncbi request reprint Suppressive effects of melatonin on amyloid-beta-induced glial activation in rat hippocampus
    Yuxian Shen
    Institute of Clinical Pharmacology, Anhui Medical University, Hefei, P R China
    Arch Med Res 38:284-90. 2007
    ..The purpose of the present study was to investigate, in vivo, the effects of melatonin on glia activation, which may contribute to improved learning and memory in amnesic rats induced by amyloid-beta peptide 25-35 (Abeta25-35)...
  4. ncbi request reprint Melatonin reduces memory changes and neural oxidative damage in mice treated with D-galactose
    Yu xian Shen
    Institute of Clinical Pharmacology, Anhui Medical University, Hefei, China
    J Pineal Res 32:173-8. 2002
    ..Furthermore, the antioxidative activity of melatonin on the D-galactose-treated mice may account for, at least partially, the improvement of learning and memory function in the aging and amnesic model...
  5. ncbi request reprint Melatonin blocks rat hippocampal neuronal apoptosis induced by amyloid beta-peptide 25-35
    Yu xian Shen
    Institute of Clinical Pharmacology, Anhui Medical University, Hefei, China
    J Pineal Res 32:163-7. 2002
    ..Our results suggest that melatonin may play an important role to protect neurons from Abeta(25-35)-induced apoptosis...
  6. ncbi request reprint The protective effects of melatonin from oxidative damage induced by amyloid beta-peptide 25-35 in middle-aged rats
    Y X Shen
    Institute of Clinical Pharmacology, Anhui Medical University, Hefei, China
    J Pineal Res 32:85-9. 2002
    ....
  7. ncbi request reprint Protective effects of melatonin on cortico-hippocampal neurotoxicity induced by amyloid beta-peptide 25-35
    Yu xian Shen
    Institute of Clinical Pharmacology, Anhui Medical University, Hefei 230032, China
    Acta Pharmacol Sin 23:71-6. 2002
    ..To study the effects of melatonin on primary rat cortico-hippocampal neurotoxicity induced by amyloid beta-peptide 25-35...
  8. ncbi request reprint Melatonin-selenium nanoparticles protects liver against immunological injury induced by bacillus Calmette-Guerin and lipopolysaccharide
    Hua Wang
    Institute of Clinical Pharmacology, Anhui Medical University, Hefei 230032, China
    Acta Pharmacol Sin 26:745-52. 2005
    ..The present investigation was designed to determine the protective effects of MT-Se against immunological liver injury in mice induced by bacillus Calmette-Guerin (BCG)/lipopolysaccharide (LPS)...
  9. ncbi request reprint Protective effect of melatonin against liver injury in mice induced by Bacillus Calmette-Guerin plus lipopolysaccharide
    Hua Wang
    Institute of Clinical Pharmacology, Anhui Medical University, Hefei 230032, Anhui Province, China
    World J Gastroenterol 10:2690-6. 2004
    ..To investigate the effects and mechanisms of melatonin on immunological liver injury in mice...
  10. ncbi request reprint Anti-adjuvant arthritis of recombinant human endostatin in rats via inhibition of angiogenesis and proinflammatory factors
    Li Yue
    Institute of Clinical Pharmacology, Anhui Medical University, Hefei 230032, China
    Acta Pharmacol Sin 25:1182-5. 2004
    ..To investigate the profile of endostatin on adjuvant arthritis (AA) and angiogenesis blockade in synovitis...
  11. ncbi request reprint Glucosides of Chaenomeles speciosa remit rat adjuvant arthritis by inhibiting synoviocyte activities
    Min Dai
    Institute of Clinical Pharmacology, Anhui Medical University, Hefei 230032, China
    Acta Pharmacol Sin 24:1161-6. 2003
    ..To investigate the effects of Glucosides of Chaenomeles speciosa (GCS) on rat adjuvant arthritis (AA) and to clarify the role of synoviocytes in this process...
  12. ncbi request reprint Melatonin-selenium nanoparticles inhibit oxidative stress and protect against hepatic injury induced by Bacillus Calmette-Guérin/lipopolysaccharide in mice
    Hua Wang
    Institute of Clinical Pharmacology, Anhui Medical University, Hefei, Anhui Province, China
    J Pineal Res 39:156-63. 2005
    ..These results suggest that the mode of MT-Se hepatic protective action is, at least in part, related to its antioxidant properties...
  13. ncbi request reprint Oral and nasal administration of chicken type II collagen suppresses adjuvant arthritis in rats with intestinal lesions induced by meloxicam
    Yong Qiu Zheng
    Institute of Clinical Pharmacology, Anhui Medical University, Hefei 230032, Anhui Province, China
    World J Gastroenterol 10:3165-70. 2004
    ..To investigate the curative effects of oral and nasal administration of chicken type II collagen (CII) on adjuvant arthritis (AA) in rats with meloxicam-induced intestinal lesions...
  14. ncbi request reprint Effects and mechanisms of melatonin on immune responses in mice of different months
    Wei Wei
    Institute of Clinical Pharmacology, Anhui Medical University, Hefei 230032, China
    Acta Pharmacol Sin 24:719-23. 2003
    ..To study the effects and mechanisms of melatonin (MT) on immune responses in mice of different months...
  15. ncbi request reprint Activated macrophage-like synoviocytes are resistant to endoplasmic reticulum stress-induced apoptosis in antigen-induced arthritis
    Li Jie Feng
    School of Basic Medical Science, Anhui Medical University, 69 Meishan Road, 230032, Hefei, China
    Inflamm Res 63:335-46. 2014
    ..To explore the characteristic expression of endoplasmic reticulum (ER) stress protein in antigen-induced arthritis models and the role of ER stress in arthritis...
  16. ncbi request reprint [Expression of a novel metastasis-inducing protein human anterior gradient-2 (AGR2) in breast cancer and its clinical and prognostic significance]
    Zheng Sheng Wu
    Department of Pathology, Anhui Medical University, Hefei 230032, China
    Zhonghua Bing Li Xue Za Zhi 37:109-13. 2008
    ..To investigate the expression of a novel metastasis-inducing protein human anterior gradient-2 (AGR2) in breast cancer and its clinical and prognostic significance...
  17. pmc Antiproliferation and apoptosis induction of paeonol in HepG2 cells
    Shu Ping Xu
    Institute of Clinical Pharmacology of Anhui Medical University, Key Laboratory of Antiinflammatory and Immunological Pharmacology in Anhui Province, Hefei 230032, Anhui Province, China
    World J Gastroenterol 13:250-6. 2007
    ....
  18. ncbi request reprint Peroxisome proliferator-activated receptor-α activation protects against endoplasmic reticulum stress-induced HepG2 cell apoptosis
    Wei Xiang Tang
    Department of Anesthesiology, First Affiliated Hospital of Anhui Medical University, 288 Ji xi Rd, Hefei, 230022, China
    Mol Cell Biochem 385:179-90. 2014
    ..PPARα activation protects against H2O2-induced HepG2 cell apoptosis. The underlying mechanisms may be associated with its activation to suppress excessive ER stress...
  19. ncbi request reprint Blockage of the formation of new blood vessels by recombinant human endostatin contributes to the regression of rat adjuvant arthritis
    Li Yue
    Institute of Clinical Pharmacology, Anhui Medical University, Hefei 230032, PR China
    Eur J Pharmacol 567:166-70. 2007
    ..Further, endostatin decreased the expression of VEGF in both cartilage and synovial tissue. These suggest that endostatin inhibiting VEGF expression contributes to the regression of rat adjuvant arthritis...
  20. ncbi request reprint Cultured rat cortical astrocytes synthesize melatonin: absence of a diurnal rhythm
    Ya Jing Liu
    Hefei National Laboratory for Physical Sciences at Microscale, School of Life Sciences, University of Science and Technology of China USTC, Hefei, Anhui, China
    J Pineal Res 43:232-8. 2007
    ..Release of melatonin into the culture medium showed no diurnal changes. These point to astrocytes as a local source of melatonin in the rat brain. Its exact physiological function remains a topic for future studies...
  21. pmc Induction profile of MANF/ARMET by cerebral ischemia and its implication for neuron protection
    Yong qiang Yu
    Department of Radiology of the First Affiliated Hospital, Anhui Medical University, Hefei, China
    J Cereb Blood Flow Metab 30:79-91. 2010
    ..Treatment with recombinant human ARMET promoted neuron proliferation and prevented from neuron apoptosis induced by tunicamycin. These results suggest that cerebral ischemia-induced ARMET expression may be protective to the neurons...
  22. ncbi request reprint Enhanced expression of the decoy receptor IL-13Ralpha2 in macrophages of Schistosoma japonicum-infected mice
    Wei Wang
    Department of Epidemiology and Biostatistics, Anhui Medical University, Hefei, China
    Chin Med J (Engl) 122:1650-4. 2009
    ..mansoni) infection, but little is known about the location and expression level of IL-13Ralpha2 in the context of S. japonicum infection...