Ulises Urzua

Summary

Affiliation: Independencia 1027
Location: Santiago, Chile

Publications

  1. Urzua U, Best L, Munroe D. Microarray proteomic analysis discriminates tumorigenic mouse ovarian surface epithelial cells of divergent aggressive potential. Mol Biosyst. 2010;6:2521-8 pubmed publisher
    ..The molecular basis accounting for a high aggressive potential not necessarily related to an increased tumor growth capacity is discussed on a pathway-network basis. ..
  2. request reprint
    Maldonado V, Espinosa M, Pruefer F, Patino N, Ceballos Canciono G, Urzua U, et al. Gene regulation by BCL3 in a cervical cancer cell line. Folia Biol (Praha). 2010;56:183-93 pubmed
    ..We validated STAT3 as a bona fide target of BCL3 by additional interference RNA and in silico analyses of previously reported lymphoma patients. ..
  3. Urzua U, Owens G, Zhang G, Cherry J, Sharp J, Munroe D. Tumor and reproductive traits are linked by RNA metabolism genes in the mouse ovary: a transcriptome-phenotype association analysis. BMC Genomics. 2010;11 Suppl 5:S1 pubmed publisher
    ..We speculate that repetitive cycling instead of repetitive ovulations represent the actual link between ovarian tumorigenesis and reproductive records. ..
  4. Gonzalez S, Aguilera S, Alliende C, Urzua U, Quest A, Herrera L, et al. Alterations in type I hemidesmosome components suggestive of epigenetic control in the salivary glands of patients with Sjögren's syndrome. Arthritis Rheum. 2011;63:1106-15 pubmed publisher
  5. Mattison K, Corneau N, Berg I, Bosch A, Duizer E, Gutierrez Aguirre I, et al. Development and validation of a microarray for the confirmation and typing of norovirus RT-PCR products. J Virol Methods. 2011;173:233-50 pubmed publisher
    ..0 as a strain typing tool is the difficulty obtaining a long, specific amplicon from all circulating norovirus strains. Data obtained with the longer region AD amplicon provided the best discrimination between norovirus strains. ..
  6. Urzua U, Ampuero S, Roby K, Owens G, Munroe D. Dysregulation of mitotic machinery genes precedes genome instability during spontaneous pre-malignant transformation of mouse ovarian surface epithelial cells. BMC Genomics. 2016;17:728 pubmed
    ....
  7. request reprint
    Urzua U, Roby K, Gangi L, Cherry J, Powell J, Munroe D. Transcriptomic analysis of an in vitro murine model of ovarian carcinoma: functional similarity to the human disease and identification of prospective tumoral markers and targets. J Cell Physiol. 2006;206:594-602 pubmed
    ..Taken together, our findings support the utility of MOSE cells in studying ovarian cancer biology and as a source of novel diagnostic and therapeutic targets. ..

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Detail Information

Publications7

  1. Urzua U, Best L, Munroe D. Microarray proteomic analysis discriminates tumorigenic mouse ovarian surface epithelial cells of divergent aggressive potential. Mol Biosyst. 2010;6:2521-8 pubmed publisher
    ..The molecular basis accounting for a high aggressive potential not necessarily related to an increased tumor growth capacity is discussed on a pathway-network basis. ..
  2. request reprint
    Maldonado V, Espinosa M, Pruefer F, Patino N, Ceballos Canciono G, Urzua U, et al. Gene regulation by BCL3 in a cervical cancer cell line. Folia Biol (Praha). 2010;56:183-93 pubmed
    ..We validated STAT3 as a bona fide target of BCL3 by additional interference RNA and in silico analyses of previously reported lymphoma patients. ..
  3. Urzua U, Owens G, Zhang G, Cherry J, Sharp J, Munroe D. Tumor and reproductive traits are linked by RNA metabolism genes in the mouse ovary: a transcriptome-phenotype association analysis. BMC Genomics. 2010;11 Suppl 5:S1 pubmed publisher
    ..We speculate that repetitive cycling instead of repetitive ovulations represent the actual link between ovarian tumorigenesis and reproductive records. ..
  4. Gonzalez S, Aguilera S, Alliende C, Urzua U, Quest A, Herrera L, et al. Alterations in type I hemidesmosome components suggestive of epigenetic control in the salivary glands of patients with Sjögren's syndrome. Arthritis Rheum. 2011;63:1106-15 pubmed publisher
  5. Mattison K, Corneau N, Berg I, Bosch A, Duizer E, Gutierrez Aguirre I, et al. Development and validation of a microarray for the confirmation and typing of norovirus RT-PCR products. J Virol Methods. 2011;173:233-50 pubmed publisher
    ..0 as a strain typing tool is the difficulty obtaining a long, specific amplicon from all circulating norovirus strains. Data obtained with the longer region AD amplicon provided the best discrimination between norovirus strains. ..
  6. Urzua U, Ampuero S, Roby K, Owens G, Munroe D. Dysregulation of mitotic machinery genes precedes genome instability during spontaneous pre-malignant transformation of mouse ovarian surface epithelial cells. BMC Genomics. 2016;17:728 pubmed
    ....
  7. request reprint
    Urzua U, Roby K, Gangi L, Cherry J, Powell J, Munroe D. Transcriptomic analysis of an in vitro murine model of ovarian carcinoma: functional similarity to the human disease and identification of prospective tumoral markers and targets. J Cell Physiol. 2006;206:594-602 pubmed
    ..Taken together, our findings support the utility of MOSE cells in studying ovarian cancer biology and as a source of novel diagnostic and therapeutic targets. ..