Hector Toledo

Summary

Affiliation: Universidad de Chile
Country: Chile

Publications

  1. ncbi Acid stress response in Helicobacter pylori
    Hector Toledo
    Programa de Biologia Celular y Molecular, ICBM, Facultad de Medicina, Universidad de Chile, Casilla 70086, Santiago, Chile
    FEMS Microbiol Lett 213:67-72. 2002
  2. ncbi Novel genotypes in Helicobacter pylori involving domain V of the 23S rRNA gene
    Leonardo Garrido
    Programa de Biologia Celular y Molecular, ICBM, Facultad de Medicina, Universidad de Chile, Avenida Independencia 1027, Casilla 70086, Santiago 7, Chile
    Helicobacter 12:505-9. 2007
  3. ncbi Arginine 66 residue of Fur is required for the regulatory function of this protein in the acid adaptation mechanism of Helicobacter pylori
    Hector Toledo
    Programa de Biologia Celular y Molecular, ICBM, Facultad de Medicina, Universidad de Chile, Avenida Independencia 1027, Casilla 70086, Santiago 7, Chile
    Helicobacter 17:16-22. 2012
  4. ncbi [Prevalence of metronidazole, clarithromycin and tetracycline resistance in Helicobacter pylori isolated from Chilean patients]
    Cristian Vallejos
    Programa de Biologia Celular y Molecular, ICBM, Facultad de Medicina, Universidad de Chile, Santiago, Chile
    Rev Med Chil 135:287-93. 2007
  5. ncbi Role of the 207-218 peptide region of Moloney murine leukemia virus integrase in enzyme catalysis
    Monica L Acevedo
    Programa de Virologia, Instituto de Ciencias Biomedicas, Facultad de Medicina, Universidad de Chile, Independencia 1027, Santiago, Chile
    Arch Biochem Biophys 495:28-34. 2010
  6. ncbi Tetracycline resistance in Chilean clinical isolates of Helicobacter pylori
    Hector Toledo
    Programa de Biologia Celular y Molecular, ICBM, Facultad de Medicina, Universidad de Chile, Avenida Independencia 1027, Casilla 70086, Santiago 7, Chile
    J Antimicrob Chemother 65:470-3. 2010
  7. ncbi Helicobacter pylori exhibits a fur-dependent acid tolerance response
    Manuel Valenzuela
    Programa de Biologia Celular y Molecular, ICBM, Facultad de Medicina, Universidad de Chile, Casilla 70086, Santiago 7, Chile
    Helicobacter 16:189-99. 2011
  8. ncbi Helicobacter pylori-induced loss of the inhibitor-of-apoptosis protein survivin is linked to gastritis and death of human gastric cells
    Manuel Valenzuela
    Laboratory of Cellular Communication, Fondo de Investigación Avanzada en Areas Prioritarias, Center for Molecular Studies of the Cell, Facultad de Medicina, Instituto de Ciencias Biomedicas, Universidad de Chile, Pontificia Universidad Catolica de Chile, Santiago, Chile
    J Infect Dis 202:1021-30. 2010

Collaborators

  • Ana Maria Madrid
  • Monica L Acevedo
  • Manuel Valenzuela
  • Leonardo Garrido
  • Cristian Vallejos
  • Alberto Paradela
  • Juan P Albar
  • Denisse Bravo
  • Alejandro H Corvalan
  • Andrew F G Quest
  • Hery Urra
  • Guillermo Perez-Perez
  • Gonzalo Carrasco
  • Claudia Defilippi
  • Carlos Defilippi
  • Dante Cáceres

Detail Information

Publications8

  1. ncbi Acid stress response in Helicobacter pylori
    Hector Toledo
    Programa de Biologia Celular y Molecular, ICBM, Facultad de Medicina, Universidad de Chile, Casilla 70086, Santiago, Chile
    FEMS Microbiol Lett 213:67-72. 2002
    ..pylori DW504UreI-negative, a mutant strain unable to transport urea into the cell, showed a large number of proteins changed, as is typical in an acid stress response. Some of these proteins were identified by N-terminal sequencing...
  2. ncbi Novel genotypes in Helicobacter pylori involving domain V of the 23S rRNA gene
    Leonardo Garrido
    Programa de Biologia Celular y Molecular, ICBM, Facultad de Medicina, Universidad de Chile, Avenida Independencia 1027, Casilla 70086, Santiago 7, Chile
    Helicobacter 12:505-9. 2007
    ..pylori is associated with point mutations in the 23S rRNA. This study analyzes 23S rRNA gene mutations and minimum inhibitory concentration (MIC) for clarithromycin in H. pylori isolates from patients of the metropolitan region of Chile...
  3. ncbi Arginine 66 residue of Fur is required for the regulatory function of this protein in the acid adaptation mechanism of Helicobacter pylori
    Hector Toledo
    Programa de Biologia Celular y Molecular, ICBM, Facultad de Medicina, Universidad de Chile, Avenida Independencia 1027, Casilla 70086, Santiago 7, Chile
    Helicobacter 17:16-22. 2012
    ..Like other enteric bacterial pathogens, including Salmonella enterica, H. pylori develops an acid tolerance response that is dependent on the function of the transcriptional regulator protein Fur...
  4. ncbi [Prevalence of metronidazole, clarithromycin and tetracycline resistance in Helicobacter pylori isolated from Chilean patients]
    Cristian Vallejos
    Programa de Biologia Celular y Molecular, ICBM, Facultad de Medicina, Universidad de Chile, Santiago, Chile
    Rev Med Chil 135:287-93. 2007
    ..Helicobacter pylori is a pathogenic bacterium that infects a significant number of individuals. At present, therapeutic strategies to eradicate this bacterium depend on our knowledge of its resistance to antimicrobials...
  5. ncbi Role of the 207-218 peptide region of Moloney murine leukemia virus integrase in enzyme catalysis
    Monica L Acevedo
    Programa de Virologia, Instituto de Ciencias Biomedicas, Facultad de Medicina, Universidad de Chile, Independencia 1027, Santiago, Chile
    Arch Biochem Biophys 495:28-34. 2010
    ..We propose that the peptide region 207-216 is a flexible loop and that H208, Y211, R212 and Q214 of this loop are involved in the correct assembly of the DNA-integrase complex during integration...
  6. ncbi Tetracycline resistance in Chilean clinical isolates of Helicobacter pylori
    Hector Toledo
    Programa de Biologia Celular y Molecular, ICBM, Facultad de Medicina, Universidad de Chile, Avenida Independencia 1027, Casilla 70086, Santiago 7, Chile
    J Antimicrob Chemother 65:470-3. 2010
    ..pylori clinical isolates obtained from Santiago, Chile by using a recently reported molecular assay...
  7. ncbi Helicobacter pylori exhibits a fur-dependent acid tolerance response
    Manuel Valenzuela
    Programa de Biologia Celular y Molecular, ICBM, Facultad de Medicina, Universidad de Chile, Casilla 70086, Santiago 7, Chile
    Helicobacter 16:189-99. 2011
    ..This two-step acid tolerance response (ATR) requires de novo protein synthesis and is dependent on the function of the global regulatory protein Fur...
  8. ncbi Helicobacter pylori-induced loss of the inhibitor-of-apoptosis protein survivin is linked to gastritis and death of human gastric cells
    Manuel Valenzuela
    Laboratory of Cellular Communication, Fondo de Investigación Avanzada en Areas Prioritarias, Center for Molecular Studies of the Cell, Facultad de Medicina, Instituto de Ciencias Biomedicas, Universidad de Chile, Pontificia Universidad Catolica de Chile, Santiago, Chile
    J Infect Dis 202:1021-30. 2010
    ..Finally, overexpression of survivin in human gastric cells was sufficient to reduce cell death after infection. Taken together, these findings implicate survivin as an important survival factor in the gastric mucosa of humans...