Juan Francisco Santibanez
Affiliation: Universidad de Chile
- TGF-beta(1) and Smad4 overexpression induce a less invasive phenotype in highly invasive spindle carcinoma cellsJuan Francisco Santibanez
Laboratorio de Biologia Celular, INTA, Universidad de Chile, Casilla 138, Santiago 11, Chile
FEBS Lett 520:171-6. 2002..This activation was abolished with a dominant-negative Smad4 construct. These results lead us to conclude that both TGF-beta(1) and Smad4 overexpression reduce the invasive potential of Car C cells, probably via the Smad pathway...
- Transforming growth factor-beta1 modulates matrix metalloproteinase-9 production through the Ras/MAPK signaling pathway in transformed keratinocytesJuan Francisco Santibanez
Laboratorio de Biologia Celular, INTA, Universidad de Chile Casilla 138, Santiago, Chile
Biochem Biophys Res Commun 296:267-73. 2002....
- Cyclic AMP inhibits TGFbeta1-induced cell-scattering and invasiveness in murine-transformed keratinocytesJuan F Santibanez
Laboratorio de Biología Celular INTA, Universidad de Chile, Santiago, Chile
Int J Cancer 107:715-20. 2003..The latter responses seem to depend on the activity of protein kinase A, as demonstrated by the activation of the Ras-ERK pathway by specific protein kinase A inhibitors...
- EGF receptor transactivation by urokinase receptor stimulus through a mechanism involving Src and matrix metalloproteinasesJavier Guerrero
Laboratorio de Biologia Celular, INTA, Universidad de Chile, Santiago 11, Chile
Exp Cell Res 292:201-8. 2004....