J Cristian Salgado

Summary

Affiliation: Universidad de Chile
Country: Chile

Publications

  1. ncbi request reprint Is it possible to predict the average surface hydrophobicity of a protein using only its amino acid composition?
    J Cristian Salgado
    Department of Chemical Engineering and Biotechnology, Millennium Institute for Advanced Studies in Cell Biology and Biotechnology, University of Chile, Santiago
    J Chromatogr A 1075:133-43. 2005
  2. pmc Mathematical modeling of the dynamic storage of iron in ferritin
    J Cristian Salgado
    Laboratory of Process Modeling and Distributed Computing, Department of Chemical Engineering and Biotechnology, University of Chile, Santiago, Chile
    BMC Syst Biol 4:147. 2010
  3. ncbi request reprint Prediction of the partitioning behaviour of proteins in aqueous two-phase systems using only their amino acid composition
    J Cristian Salgado
    Centre for Biochemical Engineering and Biotechnology, Department of Chemical Engineering and Biotechnology, Millennium Institute for Cell Dynamics and Biotechnology, University of Chile, Santiago, Region Metropolitana, Chile
    J Chromatogr A 1178:134-44. 2008
  4. ncbi request reprint Predicting the behaviour of proteins in hydrophobic interaction chromatography. 2. Using a statistical description of their surface amino acid distribution
    J Cristian Salgado
    Centre for Biochemical Engineering and Biotechnology, Department of Chemical and Biotechnology Engineering, University of Chile, Beauchef 861, Santiago, Chile
    J Chromatogr A 1107:120-9. 2006
  5. ncbi request reprint Predicting the behaviour of proteins in hydrophobic interaction chromatography. 1: Using the hydrophobic imbalance (HI) to describe their surface amino acid distribution
    J Cristian Salgado
    Centre for Biochemical Engineering and Biotechnology, Department of Chemical and Biotechnology Engineering, University of Chile, Beauchef 861, Santiago, Chile
    J Chromatogr A 1107:110-9. 2006
  6. ncbi request reprint Prediction of retention times of proteins in hydrophobic interaction chromatography using only their amino acid composition
    J Cristian Salgado
    Centre for Biochemical Engineering and Biotechnology, Department of Chemical and Biotechnology Engineering, University of Chile, Beauchef 861, Santiago, Chile
    J Chromatogr A 1098:44-54. 2005
  7. doi request reprint Methods of calculating protein hydrophobicity and their application in developing correlations to predict hydrophobic interaction chromatography retention
    Andrea Mahn
    Department of Chemical Engineering, University of Santiago of Chile, Av Libertador Bernardo O Higgins 3363, Santiago, Chile
    J Chromatogr A 1216:1838-44. 2009
  8. pmc Modeling heterocyst pattern formation in cyanobacteria
    Ziomara P Gerdtzen
    Centre for Biochemical Engineering and Biotechnology, Department of Chemical Engineering and Biotechnology, University of Chile, Av, Beauchef 850, Santiago 837 0448, Chile
    BMC Bioinformatics 10:S16. 2009
  9. ncbi request reprint Current insights on protein behaviour in hydrophobic interaction chromatography
    M Elena Lienqueo
    Centre for Biochemical Engineering and Biotechnology, Department of Chemical and Biotechnology Engineering, University of Chile, Beauchef 861, Santiago, Chile
    J Chromatogr B Analyt Technol Biomed Life Sci 849:53-68. 2007
  10. doi request reprint Iron-induced reactive oxygen species mediate transporter DMT1 endocytosis and iron uptake in intestinal epithelial cells
    Andrés Esparza
    Iron and Biology of Aging Laboratory, Department of Biology, Faculty of Sciences, University of Chile, Santiago, Chile
    Am J Physiol Cell Physiol 309:C558-67. 2015

Detail Information

Publications11

  1. ncbi request reprint Is it possible to predict the average surface hydrophobicity of a protein using only its amino acid composition?
    J Cristian Salgado
    Department of Chemical Engineering and Biotechnology, Millennium Institute for Advanced Studies in Cell Biology and Biotechnology, University of Chile, Santiago
    J Chromatogr A 1075:133-43. 2005
    ..5% and 5.5% for the linear and the neural network models, respectively) than models that use the information about the three-dimensional structure of proteins...
  2. pmc Mathematical modeling of the dynamic storage of iron in ferritin
    J Cristian Salgado
    Laboratory of Process Modeling and Distributed Computing, Department of Chemical Engineering and Biotechnology, University of Chile, Santiago, Chile
    BMC Syst Biol 4:147. 2010
    ..A set of differential equations were established considering kinetic expressions for the main reactions and mass balances for ferritin, iron and a discrete population of ferritin species defined by their respective iron content...
  3. ncbi request reprint Prediction of the partitioning behaviour of proteins in aqueous two-phase systems using only their amino acid composition
    J Cristian Salgado
    Centre for Biochemical Engineering and Biotechnology, Department of Chemical Engineering and Biotechnology, Millennium Institute for Cell Dynamics and Biotechnology, University of Chile, Santiago, Region Metropolitana, Chile
    J Chromatogr A 1178:134-44. 2008
    ..We found that the predictive capacities of the ATPS I model are better in PEG/dextran systems, where the relative error of the prediction with respect to the experimental value is 15.6%...
  4. ncbi request reprint Predicting the behaviour of proteins in hydrophobic interaction chromatography. 2. Using a statistical description of their surface amino acid distribution
    J Cristian Salgado
    Centre for Biochemical Engineering and Biotechnology, Department of Chemical and Biotechnology Engineering, University of Chile, Beauchef 861, Santiago, Chile
    J Chromatogr A 1107:120-9. 2006
    ..7%. In addition, this model allowed us to diminish the number of variables required, increasing, in this way, the degrees of freedom of the model...
  5. ncbi request reprint Predicting the behaviour of proteins in hydrophobic interaction chromatography. 1: Using the hydrophobic imbalance (HI) to describe their surface amino acid distribution
    J Cristian Salgado
    Centre for Biochemical Engineering and Biotechnology, Department of Chemical and Biotechnology Engineering, University of Chile, Beauchef 861, Santiago, Chile
    J Chromatogr A 1107:110-9. 2006
    ..By using this multivariable model, a correlation coefficient of 0.899 was obtained. With this model, we managed to improve the predictive characteristics shown by previous models based on ASH by 31.8%...
  6. ncbi request reprint Prediction of retention times of proteins in hydrophobic interaction chromatography using only their amino acid composition
    J Cristian Salgado
    Centre for Biochemical Engineering and Biotechnology, Department of Chemical and Biotechnology Engineering, University of Chile, Beauchef 861, Santiago, Chile
    J Chromatogr A 1098:44-54. 2005
    ..In fact, the performance of the best model based on the aminoacidic composition was 5% better than that observed in the model based on the three-dimensional structure of proteins...
  7. doi request reprint Methods of calculating protein hydrophobicity and their application in developing correlations to predict hydrophobic interaction chromatography retention
    Andrea Mahn
    Department of Chemical Engineering, University of Santiago of Chile, Av Libertador Bernardo O Higgins 3363, Santiago, Chile
    J Chromatogr A 1216:1838-44. 2009
    ..These methodologies consider either knowledge of the three-dimensional structure or the amino acid composition of proteins. Despite some restrictions; they have proven to be useful in predicting protein retention time in HIC...
  8. pmc Modeling heterocyst pattern formation in cyanobacteria
    Ziomara P Gerdtzen
    Centre for Biochemical Engineering and Biotechnology, Department of Chemical Engineering and Biotechnology, University of Chile, Av, Beauchef 850, Santiago 837 0448, Chile
    BMC Bioinformatics 10:S16. 2009
    ..In this paper, the process by which cyanobacteria differentiates from vegetative cells into heterocysts in the absence of nitrogen and the elements of the gene network involved that allow the formation of such a pattern are investigated...
  9. ncbi request reprint Current insights on protein behaviour in hydrophobic interaction chromatography
    M Elena Lienqueo
    Centre for Biochemical Engineering and Biotechnology, Department of Chemical and Biotechnology Engineering, University of Chile, Beauchef 861, Santiago, Chile
    J Chromatogr B Analyt Technol Biomed Life Sci 849:53-68. 2007
    ....
  10. doi request reprint Iron-induced reactive oxygen species mediate transporter DMT1 endocytosis and iron uptake in intestinal epithelial cells
    Andrés Esparza
    Iron and Biology of Aging Laboratory, Department of Biology, Faculty of Sciences, University of Chile, Santiago, Chile
    Am J Physiol Cell Physiol 309:C558-67. 2015
    ..Taken together, our data suggest that iron uptake induces the production of ROS, which modify DMT1 endocytic cycling, thus changing the iron transport activity at the apical membrane. ..
  11. pmc Mathematical Modeling of Intestinal Iron Absorption Using Genetic Programming
    Andrea Colins
    Laboratory of Process Modeling and Distributed Computing, Department of Chemical Engineering and Biotechnology, University of Chile, Santiago, Chile
    PLoS ONE 12:e0169601. 2017
    ..This general method holds great potential for application to the elucidation of biological mechanisms and their key components in other complex systems...