Research Topics
| Miguel L O'RyanSummaryAffiliation: Universidad de Chile Country: Chile Publications
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Detail Information
Publications
Update on Rotarix: an oral human rotavirus vaccineMiguel O'Ryan
Professor and Associate Director, Institute of Biomedical Sciences, Faculty of Medicine, University of Chile, Santiago, Chile
Expert Rev Vaccines 8:1627-41. 2009....
Enteric viruses in wastewaters: an interesting approach to evaluate the potential impact of rotavirus vaccination on viral circulationMiguel L O'Ryan
University of Chile, Diagonal Paraguay 265, Office 1403, Santiago, Centro, Chile
Expert Rev Vaccines 11:419-22. 2012..These results suggest that rotavirus circulation may be positively affected by vaccination and support the use of enteric viral detection in wastewaters as a useful tool to measure the impact of specific interventions...- Rotarix (RIX4414): an oral human rotavirus vaccineMiguel O'Ryan
Institute of Biomedical Sciences, Faculty of Medicine, University of Chile, Chile
Expert Rev Vaccines 6:11-9. 2007.... - Impact of rotavirus infections on outpatient clinic visits in chileMiguel O'Ryan
Microbiology and Mycology Program, Institute of Biomedical Sciences, Faculty of Medicine, University of Chile
Pediatr Infect Dis J 26:41-5. 2007..We previously estimated a yearly incidence of 8000 and 53,000 hospitalizations and emergency room visits respectively for children <or=3 years of age... - New rotavirus vaccines: renewed optimismDavid O Matson
Institute of Biomedical Sciences, Faculty of Medicine, University of Chile, Santiago, Chile
J Pediatr 149:448-51. 2006 - The ever-changing landscape of rotavirus serotypesMiguel O'Ryan
Institute of Biomedical Sciences, Faculty of Medicine, University of Chile, Santiago, Chile
Pediatr Infect Dis J 28:S60-2. 2009..The heterogeneity and ever-changing epidemiology of rotavirus underscores the need for continued surveillance to ensure that vaccination programs provide optimal protection... - Rotavirus vaccines for the developing worldMiguel L O'Ryan
Microbiology and Mycology Program, Institute of Biomedical Sciences, Faculty of Medicine, University of Chile, Santiago, Chile
Curr Opin Infect Dis 22:483-9. 2009..The review will focus on the role of the vaccines for the developing world but this does not preclude the relevance of these vaccines for children living in the industrialized world... - Symptomatic and asymptomatic rotavirus and norovirus infections during infancy in a Chilean birth cohortMiguel L O'Ryan
Microbiology and Mycology Program, Institute of Biomedical Sciences, Faculty of Medicine, Universidad de Chile
Pediatr Infect Dis J 28:879-84. 2009..Comparative analysis of these infections in a birth cohort has not been performed and can provide relevant insight on clinical and viral behaviors... - [New rotavirus vaccines: a reality at last]Miguel O'Ryan
Programa de Microbiología y Micología, Instituto de Ciencias Biomedicas, Facultad de Medicina, Universidad de Chile
Rev Chilena Infectol 22:345-54. 2005.... - An update on management of severe acute infectious gastroenteritis in childrenMiguel O'Ryan
Institute of Biomedical Sciences, Faculty of Medicine, University of Chile, Santiago, Chile
Expert Rev Anti Infect Ther 8:671-82. 2010..The article will also briefly discuss current preventive measures against rotavirus gastroenteritis through vaccination, a topic that has been extensively discussed elsewhere... - A millennium update on pediatric diarrheal illness in the developing worldMiguel O'Ryan
Microbiology and Mycology Program, Institute of Biomedical Sciences, Faculty of Medicine, University of Chile, Santiago
Semin Pediatr Infect Dis 16:125-36. 2005..Preventive measures include careful personal hygiene, especially promotion of hand washing. Immunizations currently or soon to be available for Salmonella serotype Typhi, cholera prevention, and rotavirus are discussed... - Prospective characterization of norovirus compared with rotavirus acute diarrhea episodes in chilean childrenMiguel L O'Ryan
Microbiology and Mycology Program, Institute of Biomedical Sciences, Faculty of Medicine, Universidad de Chile, Santiago, Chile
Pediatr Infect Dis J 29:855-9. 2010..Comparing epidemiologic and clinical features of norovirus to rotavirus ADE will aid in the decision-making process required to develop norovirus vaccines... - Rotarix®: vaccine performance 6 years postlicensureMiguel O'Ryan
Programa de Microbiología y Micología, Instituto de Ciencias Biomedicas, Facultad de Medicina, Universidad de Chile, Santiago, Chile
Expert Rev Vaccines 10:1645-59. 2011.... 
Caliciviruses and foodborne gastroenteritis, ChileRoberto Vidal
Microbiology Program, Institute of Biomedical Sciences, Faculty of Medicine, University of Chile, Santiago, Chile
Emerg Infect Dis 11:1134-7. 2005..Outbreaks affected ?99 persons, occurred most commonly in the home, and were associated with seafood consumption. Thirteen outbreak strains sequenced were noroviruses, including 8 GII, 2 GI, and 3 belonging to a novel genogroup...- Dynamics of Helicobacter pylori Detection in Stools During the First 5 Years of Life in Chile, a Rapidly Developing CountryMiguel L O'Ryan
From the Microbiology and Mycology Program, Institute of Biomedical Sciences Postgraduate Program, School of Medicine, Faculty of Medicine Infectious Disease Unit, Hospital Luis Calvo Mackenna, Departament of Pediatrics, Faculty of Medicine, Universidad de Chile and Pediatric Service, Hospital Sotero del Rio, Santiago, Chile
Pediatr Infect Dis J 32:99-103. 2013..We aimed to characterize the dynamics of H. pylori stool detection and to determine host and environmental factors and symptoms associated with persistence... - Immunogenicity and tolerability of a multicomponent meningococcal serogroup B (4CMenB) vaccine in healthy adolescents in Chile: a phase 2b/3 randomised, observer-blind, placebo-controlled studyMaría Elena Santolaya
Departamento de Pediatria, Hospital Dr Luis Calvo Mackenna, Facultad de Medicina, Universidad de Chile, Santiago, Chile
Lancet 379:617-24. 2012..We assessed immunogenicity and tolerability of a four-component vaccine (4CMenB) in adolescents... - Efficacy of a pentavalent rotavirus vaccine in reducing rotavirus-associated health care utilization across three regions (11 countries)Timo Vesikari
University of Tampere Medical School, Tampere, Finland
Int J Infect Dis 11:S29-35. 2007.... - On a multinational assessment of rotavirus disease in europeDavid O Matson
J Infect Dis 195:S1-3. 2007 - The pentavalent rotavirus vaccine, RotaTeqDavid O Matson
Graduate Program in Public Health, Eastern Virginia Medical School, Old Dominion University, Norfolk, VA 23501, USA
Semin Pediatr Infect Dis 17:195-9. 2006..A pentavalent rotavirus vaccine, PRV, is the second FDA-licensed rotavirus vaccine and does not signal the risk observed with RRV-TV. The properties and large safety study results of PRV are reviewed here... - Clinical presentations of rotavirus infection among hospitalized childrenMary Allen Staat
Division of Infectious Disease, Children s Hospital Medical Center, Cincinnati, OH 45229, USA
Pediatr Infect Dis J 21:221-7. 2002..Although rotaviruses (RVs) are the most common cause of severe gastroenteritis in children, there is a lack of information detailing the spectrum of clinical manifestations of RV disease resulting in hospitalization... - Genetic variation of capsid protein VP7 in genotype g4 human rotavirus strains: simultaneous emergence and spread of different lineages in ArgentinaKarin Bok
Viral Gastroenteritis Laboratory, National Institute of Infectious Diseases, Buenos Aires, Argentina
J Clin Microbiol 40:2016-22. 2002..The appearance of at least two G4 genotype (sub)lineages during 1998 demonstrates that the increased frequency of these strains was due to the synchronized emergence of different groups of strains... - Nonmedical costs associated with rotavirus disease requiring hospitalizationBrian P Lee
Children s Hospital and Research Center at Oakland, Oakland, CA, USA
Pediatr Infect Dis J 24:984-8. 2005..Herein, we report the results from the largest prospective study in the United States determining the nonmedical costs of severe rotavirus infections... - Safety and efficacy of a pentavalent human-bovine (WC3) reassortant rotavirus vaccineTimo Vesikari
University of Tampere Medical School, Tampere, Finland
N Engl J Med 354:23-33. 2006..The risk of intussusception was similar in vaccine and placebo recipients. (ClinicalTrials.gov number, NCT00090233.).. - RotaShield: the ill-fated rhesus-human reassortant rotavirus vaccineDavid O Matson
Infectious Diseases Section, Center for Pediatric Research, Norfolk, VA 23510, USA
Pediatr Ann 35:44-50. 2006 - Quantitation of human astrovirus by real-time reverse-transcription-polymerase chain reaction to examine correlation with clinical illnessZhian Zhang
Center for Pediatric Research, Eastern Virginia Medical School, 855 West Brambleton Avenue, Norfolk, VA 23510, USA
J Virol Methods 134:190-6. 2006..49, p=.064), but was not associated with change in age, gender, illness day, severity or breast-feeding. RT2-PCR quantitated HAstV RNA and RNACN in stool correlates with features of clinical illness... - Rotavirus deaths: rare or unrecognized?Mary Allen Staat
University of Cincinnati, Cincinnati Children s Hospital Medical Center, Department of Pediatrics, Division of Infectious Diseases, Ohio 45229, USA
Clin Pediatr (Phila) 44:535-7. 2005 - Prevalence and genetic characterization of caliciviruses among children hospitalized for acute gastroenteritis in the United StatesCarmelann Zintz
Center for Pediatric Research, Children's Hospital of The King's Daughters, Eastern Virginia Medical School, 855 West Brambleton Avenue, Norfolk, VA 23510, USA
Infect Genet Evol 5:281-90. 2005..In conclusion, NV and SV were frequent causes of hospitalization for acute gastroenteritis in young children and infecting strains were highly diverse, including newly recognized genogroups and genetic clusters within known genogroups... - Prevalence and characterization of astroviruses in Argentinean children with acute gastroenteritisCarlos Espul
Virology Laboratory, Central Hospital, Mendoza, Argentina
J Med Virol 72:75-82. 2004..HastV-4 caused 25% of HastV infections in Mendoza, although it has been detected commonly elsewhere. Distinct genetic lineages were apparent but their epidemiological significance remains to be demonstrated... - Novel recombinant norovirus causing outbreaks of gastroenteritis in Santiago, ChileRoberto Vidal
, , Facultad de Medicina, Universidad de Chile, Santiago, Chile
J Clin Microbiol 44:2271-5. 2006..These strains belonged to a novel genogroup by RdRp sequence and to genogroup GII/3 by capsid sequence. Determining the clinical and epidemiological impact of human calicivirus recombination will require future studies... - Rotavirus antigenemia in children is associated with viremiaSarah E Blutt
Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, United States of America
PLoS Med 4:e121. 2007..We aimed to analyze a defined patient population to determine if infectious virus could be detected in sera from children with rotavirus antigenemia... - Sequence diversity of human caliciviruses recovered from children with diarrhea in Mendoza, Argentina, 1995-1998Norma Martinez
Virology Laboratory, Central Hospital, Mendoza, Argentina
J Med Virol 67:289-98. 2002....