Fernando Orrego

Summary

Affiliation: Universidad de Los Andes
Country: Chile

Publications

  1. ncbi request reprint Darwin's illness: a final diagnosis
    Fernando Orrego
    Origin of Living Beings, Faculty of Medicine, Universidad de Los Andes, Santiago 6782468, Chile
    Notes Rec R Soc Lond 61:23-9. 2007
  2. ncbi request reprint Epilepsy-induced changes in signaling systems of human and rat postsynaptic densities
    Ursula Wyneken
    Laboratorio de Neurociencias, Universidad de los, Santiago, Chile
    Epilepsia 44:243-6. 2003
  3. ncbi request reprint Electrophysiology and plasticity in isolated postsynaptic densities
    Ursula Wyneken
    Laboratorio de Neurociencias, Facultad de Medicina, Universidad de Los Andes, San Carlos de Apoquindo 2200, Las Condes, Santiago 6782468, Chile
    Brain Res Brain Res Rev 47:54-70. 2004
  4. ncbi request reprint Protein kinase CK2 in postsynaptic densities: phosphorylation of PSD-95/SAP90 and NMDA receptor regulation
    Dagoberto Soto
    Neuroscience Laboratory, Faculty of Medicine, Universidad de Los Andes, Santiago 6782468, Chile
    Biochem Biophys Res Commun 322:542-50. 2004
  5. ncbi request reprint Status epilepticus induces region-specific changes in dendritic spines, dendritic length and TrkB protein content of rat brain cortex
    Estibaliz Ampuero
    Neuroscience Laboratory, Faculty of Medicine, Universidad de Los Andes, Santiago, Chile
    Brain Res 1150:225-38. 2007
  6. ncbi request reprint Clinically relevant doses of fluoxetine and reboxetine induce changes in the TrkB content of central excitatory synapses
    Ursula Wyneken
    Neuroscience Laboratory, Faculty of Medicine, Universidad de Los Andes, Casilla, Santiago, Chile
    Neuropsychopharmacology 31:2415-23. 2006

Collaborators

  • Ursula Wyneken
  • F Aboitiz
  • E D Gundelfinger
  • Estibaliz Ampuero
  • Rodrigo Sandoval
  • Dagoberto Soto
  • Soledad Sandoval
  • Alexies Dagnino-Subiabre
  • Alejandra Viedma
  • Rodrigo Zepeda-CarreƱo
  • Juan Jose Marengo
  • Floria Pancetti
  • Mauricio Sandoval

Detail Information

Publications6

  1. ncbi request reprint Darwin's illness: a final diagnosis
    Fernando Orrego
    Origin of Living Beings, Faculty of Medicine, Universidad de Los Andes, Santiago 6782468, Chile
    Notes Rec R Soc Lond 61:23-9. 2007
    ..It apparently does not explain, however, many of his cutaneous symptoms. We do not support other diagnoses such as Chagas' disease, lactose intolerance or the many psychiatric conditions that have been postulated...
  2. ncbi request reprint Epilepsy-induced changes in signaling systems of human and rat postsynaptic densities
    Ursula Wyneken
    Laboratorio de Neurociencias, Universidad de los, Santiago, Chile
    Epilepsia 44:243-6. 2003
    ..To study seizure-induced changes in signaling proteins present in postsynaptic densities (PSDs) isolated from human epileptic neocortex and from rat cortex in which seizures were induced by injection of kainic acid...
  3. ncbi request reprint Electrophysiology and plasticity in isolated postsynaptic densities
    Ursula Wyneken
    Laboratorio de Neurociencias, Facultad de Medicina, Universidad de Los Andes, San Carlos de Apoquindo 2200, Las Condes, Santiago 6782468, Chile
    Brain Res Brain Res Rev 47:54-70. 2004
    ..The experimental approach we present will allow us to test the functional consequence of activation of the multiple signal transduction pathways thought to regulate excitatory neurotransmission in the adult CNS...
  4. ncbi request reprint Protein kinase CK2 in postsynaptic densities: phosphorylation of PSD-95/SAP90 and NMDA receptor regulation
    Dagoberto Soto
    Neuroscience Laboratory, Faculty of Medicine, Universidad de Los Andes, Santiago 6782468, Chile
    Biochem Biophys Res Commun 322:542-50. 2004
    ..These results suggest that postsynaptic NMDAR regulation by CK2 is mediated by indirect mechanisms possibly involving PSD-95/SAP90...
  5. ncbi request reprint Status epilepticus induces region-specific changes in dendritic spines, dendritic length and TrkB protein content of rat brain cortex
    Estibaliz Ampuero
    Neuroscience Laboratory, Faculty of Medicine, Universidad de Los Andes, Santiago, Chile
    Brain Res 1150:225-38. 2007
    ..The global decrease of TrkB within the neocortex and the associated dendritic atrophy may counteract seizure propagation in the epileptic brain but may also underlie cognitive impairment after seizures...
  6. ncbi request reprint Clinically relevant doses of fluoxetine and reboxetine induce changes in the TrkB content of central excitatory synapses
    Ursula Wyneken
    Neuroscience Laboratory, Faculty of Medicine, Universidad de Los Andes, Casilla, Santiago, Chile
    Neuropsychopharmacology 31:2415-23. 2006
    ..This positive feedback mechanism may help explain the time-lag between drug administration and its therapeutic effect, that is, the antidepressant drug paradox...