Manuel Olivares

Summary

Affiliation: Universidad de Chile
Country: Chile

Publications

  1. ncbi Usefulness of serum transferrin receptor and serum ferritin in diagnosis of iron deficiency in infancy
    M Olivares
    Institute of Nutrition and Food Technology, University of Chile, Santiago, Chile
    Am J Clin Nutr 72:1191-5. 2000
  2. ncbi Prevalence of anemia in elderly subjects living at home: role of micronutrient deficiency and inflammation
    M Olivares
    Instituto de Nutricion y Tecnologia de los Alimentos INTA, Universidad de Chile, Santiago, Chile
    Eur J Clin Nutr 54:834-9. 2000
  3. ncbi Nausea threshold in apparently healthy individuals who drink fluids containing graded concentrations of copper
    M Olivares
    Institute of Nutrition and Food Technology INTA, University of Chile, Macul 5540, Santiago 11, Chile
    Regul Toxicol Pharmacol 33:271-5. 2001
  4. ncbi Age and copper intake do not affect copper absorption, measured with the use of 65Cu as a tracer, in young infants
    Manuel Olivares
    Institute of Nutrition and Food Technology, University of Chile, Santiago
    Am J Clin Nutr 76:641-5. 2002
  5. ncbi Heme- and nonheme-iron absorption and iron status 12 mo after sleeve gastrectomy and Roux-en-Y gastric bypass in morbidly obese women
    Manuel Ruz
    Department of Nutrition, Faculty of Medicine, University of Chile, Santiago, Chile
    Am J Clin Nutr 96:810-7. 2012
  6. doi Iron absorption and iron status are reduced after Roux-en-Y gastric bypass
    Manuel Ruz
    Department of Nutrition, University of Chile, Santiago, Chile
    Am J Clin Nutr 90:527-32. 2009
  7. doi Trace element status and inflammation parameters after 6 months of Roux-en-Y gastric bypass
    Pamela Rojas
    Department of Nutrition, Faculty of Medicine, University of Chile, Independencia 1027, 8380453 Santiago, Chile
    Obes Surg 21:561-8. 2011
  8. doi Zinc absorption and zinc status are reduced after Roux-en-Y gastric bypass: a randomized study using 2 supplements
    Manuel Ruz
    Department of Nutrition, Faculty of Medicine, University of Chile, Santiago, Chile
    Am J Clin Nutr 94:1004-11. 2011
  9. doi Changes in bone mineral density, body composition and adiponectin levels in morbidly obese patients after bariatric surgery
    Fernando Carrasco
    Department of Nutrition, Faculty of Medicine, University of Chile, Independencia 1027, Postal Code 838 0453, Santiago, Chile
    Obes Surg 19:41-6. 2009
  10. ncbi Iron absorption from wheat flour: effects of lemonade and chamomile infusion
    Manuel Olivares
    Instituto de Nutricion y Tecnologia de los Alimentos, Universidad de Chile, Santiago, Chile
    Nutrition 23:296-300. 2007

Collaborators

Detail Information

Publications66

  1. ncbi Usefulness of serum transferrin receptor and serum ferritin in diagnosis of iron deficiency in infancy
    M Olivares
    Institute of Nutrition and Food Technology, University of Chile, Santiago, Chile
    Am J Clin Nutr 72:1191-5. 2000
    ..The serum transferrin receptor (TfR) and the ratio of TfR to serum ferritin (TfR:SF) have been shown to be useful as early indicators of iron deficiency...
  2. ncbi Prevalence of anemia in elderly subjects living at home: role of micronutrient deficiency and inflammation
    M Olivares
    Instituto de Nutricion y Tecnologia de los Alimentos INTA, Universidad de Chile, Santiago, Chile
    Eur J Clin Nutr 54:834-9. 2000
    ..Wheat-based staple foods are iron fortified in Chile. We aimed to establish the prevalence and etiology of anemia in apparently healthy free-living elderly subjects...
  3. ncbi Nausea threshold in apparently healthy individuals who drink fluids containing graded concentrations of copper
    M Olivares
    Institute of Nutrition and Food Technology INTA, University of Chile, Macul 5540, Santiago 11, Chile
    Regul Toxicol Pharmacol 33:271-5. 2001
    ....
  4. ncbi Age and copper intake do not affect copper absorption, measured with the use of 65Cu as a tracer, in young infants
    Manuel Olivares
    Institute of Nutrition and Food Technology, University of Chile, Santiago
    Am J Clin Nutr 76:641-5. 2002
    ..Copper homeostasis involves a high degree of regulation in which changes in absorption and biliary excretion are the main mechanisms. Whether neonates and small infants can make these changes efficiently is unknown...
  5. ncbi Heme- and nonheme-iron absorption and iron status 12 mo after sleeve gastrectomy and Roux-en-Y gastric bypass in morbidly obese women
    Manuel Ruz
    Department of Nutrition, Faculty of Medicine, University of Chile, Santiago, Chile
    Am J Clin Nutr 96:810-7. 2012
    ..The effect of bariatric surgery on iron absorption is only partially known...
  6. doi Iron absorption and iron status are reduced after Roux-en-Y gastric bypass
    Manuel Ruz
    Department of Nutrition, University of Chile, Santiago, Chile
    Am J Clin Nutr 90:527-32. 2009
    ..Iron deficiency and iron deficiency anemia are common in patients who undergo gastric bypass. The magnitude of change in iron absorption is not well known...
  7. doi Trace element status and inflammation parameters after 6 months of Roux-en-Y gastric bypass
    Pamela Rojas
    Department of Nutrition, Faculty of Medicine, University of Chile, Independencia 1027, 8380453 Santiago, Chile
    Obes Surg 21:561-8. 2011
    ..The objective of this study was to evaluate changes on trace element status and their potential associations with selected inflammation parameters in patients after Roux-en-Y gastric bypass (RYGBP)...
  8. doi Zinc absorption and zinc status are reduced after Roux-en-Y gastric bypass: a randomized study using 2 supplements
    Manuel Ruz
    Department of Nutrition, Faculty of Medicine, University of Chile, Santiago, Chile
    Am J Clin Nutr 94:1004-11. 2011
    ..Micronutrient deficiencies are common in patients undergoing gastric bypass. The effect of this type of surgery on zinc absorption and zinc status is not well known...
  9. doi Changes in bone mineral density, body composition and adiponectin levels in morbidly obese patients after bariatric surgery
    Fernando Carrasco
    Department of Nutrition, Faculty of Medicine, University of Chile, Independencia 1027, Postal Code 838 0453, Santiago, Chile
    Obes Surg 19:41-6. 2009
    ..To evaluate changes on BMD after GBP and its relation with changes in body composition and serum adiponectin, a longitudinal study in morbid obese subjects was conducted...
  10. ncbi Iron absorption from wheat flour: effects of lemonade and chamomile infusion
    Manuel Olivares
    Instituto de Nutricion y Tecnologia de los Alimentos, Universidad de Chile, Santiago, Chile
    Nutrition 23:296-300. 2007
    ..We measured iron bioavailability of meals based on wheat flour consumed by a vulnerable population in Latin America...
  11. doi Effect of Helicobacter pylori infection on iron absorption in asymptomatic adults consuming wheat flour fortified with iron and zinc
    Daniel Lopez de Romaña
    Instituto de Nutricion y Tecnologia de los Alimentos, Universidad de Chile, Avenida El Líbano, 5524, Macul, Santiago, Chile
    Biol Trace Elem Res 144:1318-26. 2011
    ..3 ± 3.3% vs. 0.3 ± 2.7%, p = 0.11). H. pylori infection has a negative effect on iron absorption in asymptomatic adults consuming iron- and zinc-fortified wheat flour...
  12. doi Effect of increasing levels of zinc fortificant on the iron absorption of bread co-fortified with iron and zinc consumed with a black tea
    Manuel Olivares
    Institute of Nutrition and Food Technology, University of Chile, Santiago, Chile
    Biol Trace Elem Res 154:321-5. 2013
    ....
  13. ncbi Differential response of interleukin-2 production to chronic copper supplementation in healthy humans
    Carlos Munoz
    Institute of Nutrition and Food Technology INTA, University of Chile, Casilla 138 11, Santiago, Chile
    Eur Cytokine Netw 16:261-5. 2005
    ..Copper (Cu) is an essential trace element for many biological processes including maintenance of both innate and acquired branches of immunity...
  14. ncbi New insights about iron bioavailability inhibition by zinc
    Manuel Olivares
    Institute of Nutrition and Food Technology, University of Chile, Santiago, Chile
    Nutrition 23:292-5. 2007
    ..We measured the effects of lower and higher doses of zinc (Zn) given as an aqueous solution on the bioavailability of iron (Fe)...
  15. ncbi CCS and SOD1 mRNA are reduced after copper supplementation in peripheral mononuclear cells of individuals with high serum ceruloplasmin concentration
    Miriam Suazo
    Laboratory of Micronutrients, University of Chile INTA, Santiago, Chile
    J Nutr Biochem 19:269-74. 2008
    ..However, CCS and SOD1 mRNA levels were reduced in PMNCs after copper supplementation in the individuals with the high Cp values, suggesting that they should be further explored as biomarkers of moderate copper overload in humans...
  16. doi Calcium does not inhibit the absorption of 5 milligrams of nonheme or heme iron at doses less than 800 milligrams in nonpregnant women
    Diego Gaitán
    Micronutrients Laboratory, Nutrition and Food Technology Institute, University of Chile, Santiago, Chile
    J Nutr 141:1652-6. 2011
    ..This effect was observed at doses higher than previously reported from single-meal studies, starting at ~800 mg of calcium...
  17. doi Effect of increasing concentrations of zinc on the absorption of iron from iron-fortified milk
    Manuel Olivares
    Institute of Nutrition and Food Technology, University of Chile, Santiago, Chile
    Biol Trace Elem Res 150:21-5. 2012
    ..In conclusion, according to the results from this study, it appears that the addition of zinc up to 20 mg/L does not significantly inhibit iron absorption from milk fortified with 10 mg/L of iron...
  18. doi Iron, copper, and zinc transport: inhibition of divalent metal transporter 1 (DMT1) and human copper transporter 1 (hCTR1) by shRNA
    Alejandra Espinoza
    Micronutrient Laboratory, Institute of Nutrition and Food Technology, University of Chile, El Líbano, 5524 Macul, Santiago, Chile
    Biol Trace Elem Res 146:281-6. 2012
    ..These results confirm that DMT1 is involved in active transport of Fe, Cu, and Zn although Zn showed a different relative capacity. These results also show that hCTR1 is able to transport Fe and Zn...
  19. doi Acute inhibition of iron bioavailability by zinc: studies in humans
    Manuel Olivares
    Institute of Nutrition and Food Technology INTA, University of Chile, Santiago, Chile
    Biometals 25:657-64. 2012
    ..The possibility of a negative interaction should be considered for supplementation or fortification programs with both microminerals...
  20. ncbi The mechanisms for regulating absorption of Fe bis-glycine chelate and Fe-ascorbate in caco-2 cells are similar
    Dora Inés Mazariegos
    Micronutrients Laboratory, Institute of Nutrition and Food Technology INTA, Santiago, Chile
    J Nutr 134:395-8. 2004
    ..5%) did not differ from that of Fe added as Fe-AA (86.8%). These results suggest that Fe derived from Fe bis-glycine chelate and Fe-AA have similar regulatory absorption mechanisms...
  21. ncbi Case study of complaints on drinking water quality: relationship to copper content?
    Fernando Pizarro
    Instituto de Nutricion y Tecnologia de los Alimentos, Universidad de Chile, Santiago, Chile
    Biol Trace Elem Res 116:131-45. 2007
    ..The dose-response curves for GI symptoms and Cu exposure now available were crucial in the analyses of results...
  22. pmc Community-based randomized double-blind study of gastrointestinal effects and copper exposure in drinking water
    Magdalena Araya
    Institute of Nutrition and Food Technology, University of Chile, Santiago, Chile
    Environ Health Perspect 112:1068-73. 2004
    ..We conclude that exposure to Cu in drinking water results in gastrointestinal symptoms, which are modulated by Cu concentration, time, and sex...
  23. ncbi Confirmation of an acute no-observed-adverse-effect and low-observed-adverse-effect level for copper in bottled drinking water in a multi-site international study
    Magdalena Araya
    Institute of Nutrition and Food Technology INTA, University of Chile, Macul 5540, Casilla 13811, Santiago, 11, Chile
    Regul Toxicol Pharmacol 38:389-99. 2003
    ..8mg Cu (4mg Cu/L) for adult females. These data confirm a previously determined human acute NOAEL for Cu added to distilled water, and provide additional, controlled human data for determining safe concentrations of Cu in drinking water...
  24. ncbi Chilean complementary feeding program reduces anemia and improves iron status in children aged 11 to 18 months
    Alex Brito
    Micronutrients Laboratory, Institute of Nutrition and Food Technology INTA, University of Chile, Santiago, Chile
    Food Nutr Bull 34:378-85. 2013
    ..Iron deficiency is the most prevalent nutritional deficiency in the world, primarily affecting infants, young children, and women of childbearing age...
  25. ncbi Low prevalence of anemia in children aged 19 to 72 months in Chile
    Alex Brito
    Micronutrients Laboratory, Institute of Nutrition and Food Technology INTA, University of Chile, Santiago
    Food Nutr Bull 33:308-11. 2012
    ..In 1974/75, the prevalence of anemia in Chilean preschoolers was 18.8%. Since 2000, the Chilean Ministry of Health has combated anemia through the delivery of iron-fortified milk by the National Complementary Feeding Program (NCFP)...
  26. doi Effect of trypsin and mucin on heme iron bioavailability in humans
    Gustavo Cediel
    Micronutrients Laboratory, Institute of Nutrition and Food Technology INTA, University of Chile, Avda El Líbano 5524, Casilla 13811, Santiago, Chile
    Biol Trace Elem Res 150:37-41. 2012
    ..In the human gastrointestinal tract, trypsin and mucin may affect the absorption of heme iron. However, these interactions have not been well-established. We determined the effect of trypsin and mucin on heme iron absorption in humans...
  27. doi Total iron, heme iron, zinc, and copper content in rabbit meat and viscera
    Carolina Valenzuela
    Facultad de Ciencias Veterinarias y Pecuarias, Universidad de Chile, Santiago, Chile
    Biol Trace Elem Res 143:1489-96. 2011
    ..The liver had the highest Cu content (3.89 ± 0.89 mg/100 g). Rabbit meat has low TFe concentration, similar to that of poultry, and most of the iron is HeFe. The amount of minerals in viscera closely depends on their function...
  28. doi [Energy expenditure and body composition in severe and morbid obese women after gastric bypass]
    Fernando Carrasco
    Departamento de Nutricion, Facultad de Medicina, Universidad de Chile, Santiago, Chile
    Rev Med Chil 136:570-7. 2008
    ..The effects of gastric bypass (GBP) on resting energy expenditure (REE) are not well known...
  29. ncbi Iron, zinc, and copper: contents in common Chilean foods and daily intakes in Santiago, Chile
    Manuel Olivares
    Institute of Nutrition and Food Technology, University of Chile, Macul 5540, Casilla 138 11, Santiago, Chile
    Nutrition 20:205-12. 2004
    ..We determined the iron (Fe), zinc (Zn), and copper (Cu) contents of common Chilean foods and assessed the intakes of these elements in a population living in Santiago, Chile...
  30. ncbi Gastrointestinal symptoms and blood indicators of copper load in apparently healthy adults undergoing controlled copper exposure
    Magdalena Araya
    Institute of Nutrition and Food Technology, University of Chile, Santiago
    Am J Clin Nutr 77:646-50. 2003
    ..Mild and moderate effects of marginally low and marginally high copper exposure are poorly understood in humans...
  31. ncbi Ascorbyl palmitate enhances iron bioavailability in iron-fortified bread
    Fernando Pizarro
    Institute of Nutrition and Food Technology of Universidad de Chile, Santiago, Chile
    Am J Clin Nutr 84:830-4. 2006
    ..One of the strategies to control iron deficiency anemia is the fortification of food with iron. A mechanism for improving the bioavailability of iron is to add an iron absorption promoter...
  32. pmc Sex and ceruloplasmin modulate the response to copper exposure in healthy individuals
    Marco A Mendez
    Institute of Nutrition and Food Technology, University of Chile, Santiago, Chile
    Environ Health Perspect 112:1654-7. 2004
    ..The response depends on Cp values and on sex, such that women with higher and men with lower Cp values exhibit the greatest response...
  33. ncbi Less than adequate vitamin D status and intake in Latin America and the Caribbean:a problem of unknown magnitude
    Alex Brito
    Micronutrients Laboratory, Institute of Nutrition and Food Technology INTA, University of Chile, Santiago, Chile
    Food Nutr Bull 34:52-64. 2013
    ..The prevalence of vitamin D deficiency in Latin America and the Caribbean is unknown...
  34. ncbi Understanding copper homeostasis in humans and copper effects on health
    Magdalena Araya
    Institute of Nutrition and Food Technology, University of Chile, Santiago, Chile
    Biol Res 39:183-7. 2006
  35. ncbi Iron status biomarkers and C-reactive protein in children aged 19 to 72 months in Chile
    Alex Brito
    Micronutrients Laboratory, Institute of Nutrition and Food Technology INTA, University of Chile, Santiago, Chile
    Food Nutr Bull 34:14-20. 2013
    ..The Chilean Ministry of Health has combated iron deficiency through the delivery of fortified milk by the National Complementary Feeding Program (NCFP)...
  36. doi The effect of calcium on non-heme iron uptake, efflux, and transport in intestinal-like epithelial cells (Caco-2 cells)
    Diego Alejandro Gaitán
    Laboratorio de Micronutrientes, Instituto de Nutricion y Tecnologia de los Alimentos INTA, Universidad de Chile, Santiago, Chile
    Biol Trace Elem Res 145:300-3. 2012
    ..The effect of higher calcium to iron molar ratios on the efflux of non-heme iron may be large enough to explain results from human studies...
  37. ncbi Iron amino acid chelates
    Eva Hertrampf
    Institute of Nutrition and Food Technology INTA, University of Chile, Santiago
    Int J Vitam Nutr Res 74:435-43. 2004
    ..need for more rigorous efficacy trials designed to define the relative merits of amino acid chelates when compared with bioavailable iron salts such as ferrous sulfate and ferrous fumarate and to determine appropriate fortification levels..
  38. ncbi Is a 40 % absorption of iron from a ferrous ascorbate reference dose appropriate to assess iron absorption independent of iron status?
    Carolina Valenzuela
    Faculty of Veterinary and Animal Sciences, University of Chile, Santiago, Chile
    Biol Trace Elem Res 155:322-6. 2013
    ..A 40 % absorption as reference dose is only appropriate to assess Fe absorption in subjects with IDS and IDWA. SF had an inverse correlation with FeRD%, and TS increases the probability that the FeRD% will be elevated by over fivefold. ..
  39. ncbi Acute copper supplementation does not inhibit non-heme iron bioavailability in humans
    Manuel Olivares
    Institute of Nutrition and Food Technology, University of Chile, Santiago, Chile
    Biol Trace Elem Res 136:180-6. 2010
    ..Our results support the hypothesis that divalent metal transporter 1 is not physiologically relevant for copper absorption in humans...
  40. doi Ceruloplasmin, an indicator of copper status
    Miguel Arredondo
    Micronutrient Laboratory, Nutrition and Food Technology Institute INTA, University of Chile, El Líbano, 5524, Macul, Santiago, Chile
    Biol Trace Elem Res 123:261-9. 2008
    ..Our in vitro and in vivo studies indicate that, as a mean, there are 5.8 atoms of Cu per Cp molecule and that <1.3 micromol/l of Cu would correspond to the NCPC...
  41. ncbi Inhibition of iron and copper uptake by iron, copper and zinc
    Miguel Arredondo
    Micronutrients Laboratory, Institute of Nutrition and Food Technology INTA, Universidad de Chile
    Biol Res 39:95-102. 2006
    ..These results point to a potential risk in the absorption and bioavailability of these minerals by the presence of other minerals in the diet. This aspect must be considered in food supplementation and fortification programs...
  42. doi Risks and benefits of copper in light of new insights of copper homeostasis
    Daniel Lopez de Romana
    Instituto de Nutricion y Tecnologia de los Alimentos, Universidad de Chile, Avenida El Líbano 5524, Macul 5540, Macul, Santiago, Chile
    J Trace Elem Med Biol 25:3-13. 2011
    ..Developing the scientific basis for a copper UL and evaluating the relevance of copper deficiency globally are future key challenges for copper researchers...
  43. doi [Folate, vitamin B12 and human health]
    Alex Brito
    Laboratorio de Micronutrientes, Instituto de Nutricion y Tecnologia de los Alimentos, Universidad de Chile, Chile
    Rev Med Chil 140:1464-75. 2012
    ..The purpose of this review is to provide an update on recent advances in the basic and applied knowledge of these vitamins relative to human health...
  44. doi [Prevalence of zinc and copper deficiencies in older subjects living in Metropolitan Santiago]
    Manuel Olivares
    Instituto de Nutricion y Tecnologia de los Alimentos, Universidad de Chile, Santiago, Chile
    Rev Med Chil 139:283-9. 2011
    ..Older subjects have a high risk of developing zinc and copper deficiencies...
  45. ncbi Iron bioavailability in corn-masa tortillas is improved by the addition of disodium EDTA
    Tomas Walter
    Micronutrient Laboratory and Hematology Unit, Institute of Nutrition and Food Technology INTA, University of Chile, Santiago, POB 138 11, Chile
    J Nutr 133:3158-61. 2003
    ..87% to 2.9% (P < 0.001). We conclude that NaFeEDTA is the form of iron best absorbed, but alternatively, ferrous fumarate plus Na2EDTA comprises a feasible option as a fortificant...
  46. ncbi Heme-iron absorption is saturable by heme-iron dose in women
    Fernando Pizarro
    Institute of Nutrition and Food Technology INTA of University of Chile, Santiago, Chile
    J Nutr 133:2214-7. 2003
    ..5, 3, 15 and 30 mg of heme-iron as hemoglobin, respectively. The fitted curves for heme and non-heme iron differed (P < 0.04). These results strongly suggest that the heme-iron absorption pathway is saturable...
  47. ncbi Gastric response to acute copper exposure
    Magdalena Araya
    Institute of Nutrition and Food Technology INTA, University of Chile, Santiago, Chile, Casilla 138 11, Macul, Santiago, Chile
    Sci Total Environ 303:253-7. 2003
    ..No differences were found by gender or nausea. Results show a copper effect on gastric response suggesting that acute exposure to copper in water modify the first phase of gastric emptying...
  48. ncbi Iron, copper and immunocompetence
    Carlos Munoz
    INTA, University of Chile, Santiago, Chile
    Br J Nutr 98:S24-8. 2007
    ..Thus, microminerals contribute to the maintenance of the balance between immunity and health in humans...
  49. ncbi Present situation of biomarkers for copper status
    Manuel Olivares
    Institute of Nutrition and Food Technology INTA, University of Chile, Santiago, Chile
    Am J Clin Nutr 88:859S-62S. 2008
    ..Recently, we found that CCS mRNA abundance in mononuclear blood cells significantly decreased after copper supplementation. The usefulness of this indicator to detect an increase in body copper should be assessed in clinical trials...
  50. ncbi Persistent anemia after Roux-en-Y gastric bypass
    Claudio Mizón
    Department of Nutrition, Faculty of Medicine, University of Chile, Santiago, Chile
    Nutrition 23:277-80. 2007
    ..We report the case of a 42-y-old morbidly obese woman who presented persistent anemia as result of Roux-en-Y gastric bypass...
  51. doi Heme iron uptake by Caco-2 cells is a saturable, temperature sensitive and modulated by extracellular pH and potassium
    Miguel Arredondo
    Laboratorio de Micronutrientes, INTA, Universidad de Chile, Casilla 138 11, Santiago, Chile
    Biol Trace Elem Res 125:109-19. 2008
    ..The uptake of heme iron is a saturable and temperature-dependent process and, therefore, could occur through a mechanism involving both a receptor and the endocytic pathway...
  52. doi Copper supplementation at 8 mg neither affects circulating lipids nor liver function in apparently healthy Chilean men
    Loreto Rojas-Sobarzo
    Institute of Nutrition and Food Technology INTA, University of Chile, Av El Líbano 5524, Macul, Santiago, Chile
    Biol Trace Elem Res 156:1-4. 2013
    ..There were no effects on serum Cu concentration or ceruloplasmin (protein) and hepatic transaminases. Supplementation of 8 mg Cu for 6 months had no effect on lipid profile of apparently healthy Chilean men with adequate Cu status...
  53. doi Total iron and heme iron content and their distribution in beef meat and viscera
    Carolina Valenzuela
    Facultad de Ciencias Veterinarias y Pecuarias, Universidad de Chile, Santiago, Chile
    Biol Trace Elem Res 132:103-11. 2009
    ..6% in liver. Blood contained 85.5% of the radioisotope and only 1.4% was found in muscle and 1.6% was found in viscera. Results suggest that bovine cuts of meat have a low variation in TFe and that HeFe comprises more than 60% of TFe...
  54. ncbi Low prevalence of iron deficiency anemia between 1981 and 2010 in Chilean women of childbearing age
    Israel Ríos-Castillo
    Laboratorio de Micronutrientes, Instituto de Nutricion y Tecnologia de los Alimentos, Universidad de Chile, Santiago, Chile
    Salud Publica Mex 55:478-83. 2013
    ..To determine the prevalence of anemia and iron status among Chilean women of childbearing age between 1981 and 2010...
  55. doi One-month of calcium supplementation does not affect iron bioavailability: a randomized controlled trial
    Israel Ríos-Castillo
    Micronutrient Laboratory, Institute of Nutrition and Food Technology, University of Chile, Santiago, Chile World Food Program, Regional Bureau for Latin America and the Caribbean, Panama City, Panama
    Nutrition 30:44-8. 2014
    ..The aim of this study was to determine the effect of 34 d of Ca supplementation on heme Fe and non-heme Fe bioavailability in non-pregnant women of ages 33 to 47 y...
  56. ncbi Iron bis-glycine chelate competes for the nonheme-iron absorption pathway
    Fernando Pizarro
    Institute of Nutrition and Food Technology, the University of Chile, Santiago
    Am J Clin Nutr 76:577-81. 2002
    ....
  57. ncbi Copper exposure and potential biomarkers of copper metabolism
    Magdalena Araya
    Institute of Nutrition and Food Technology INTA, University of Chile, Jose Pedro Alessandri 5540, Macul, Santiago II, Chile
    Biometals 16:199-204. 2003
    ..These studies indicate that in the range of the copper homeostasis area the markers tested are not suitable to detect mild changes (within the homeostatic range) of copper metabolism...
  58. ncbi Reducing iron deficiency anemia in Bolivian school children: Calcium and iron combined versus iron supplementation alone
    Melissa Miranda
    Micronutrients Laboratory, Institute of Nutrition and Food Technology, University of Chile, Santiago, Chile
    Nutrition 30:771-5. 2014
    ..The aim of this study was to determine the effect of combined calcium and iron versus single iron supplementation on iron status in Bolivian schoolchildren...
  59. doi Effect of zinc sulfate fortificant on iron absorption from low extraction wheat flour co-fortified with ferrous sulfate
    Manuel Olivares
    Institute of Nutrition and Food Technology, University of Chile, Santiago, Chile
    Biol Trace Elem Res 151:471-5. 2013
    ..A statistically significant reduction of Fe absorption was observed at a Zn fortification level of 90 mg Zn/kg...
  60. ncbi Tumour necrosis factor-alpha transcription in transferrin-stimulated human blood mononuclear cells: is transferrin receptor involved in the signalling mechanism?
    Marcelo Lopez
    Institute of Nutrition and Food Technology, University of Chile, Santiago, Chile
    Br J Haematol 120:829-35. 2003
    ..The impaired TNF-alpha transcription in cells from ID subjects indicates that the quality of the immune response is linked to the Fe status of mononuclear cells...
  61. doi Bioavailability of stabilised ferrous gluconate with glycine in fresh cheese matrix: a novel iron compound for food fortification
    Fernando Pizarro
    Micronutrients Laboratory, Institute of Nutrition and Food Technology INTA, University of Chile, 7830489, Casilla 138 11, Santiago, Chile
    Biol Trace Elem Res 151:441-5. 2013
    ..S.). The results of the present study show that the novel iron compound ferrous gluconate stabilised with glycine in a fresh cheese matrix is a good source of iron and can be used in iron fortification programmes...
  62. ncbi Parallels and contrasts between iron and copper metabolism
    Michael D Garrick
    Department of Biochemistry, SUNY at Buffalo, NY 14214, USA
    Biometals 16:1-8. 2003
    ..Regulation of gene expression and excretion offered contrasts between the two metals. The workshop also considered a series of continuing and emerging issues...
  63. ncbi Enhancers of iron absorption: ascorbic acid and other organic acids
    Birgit Teucher
    Nutrition Division, Institute of Food Research, Norwich NR4 7UA, UK
    Int J Vitam Nutr Res 74:403-19. 2004
    ..g., condiments, beverages). However, fermented foods that already contain high levels of organic acid may be suitable iron fortification vehicles...
  64. ncbi Supplementing copper at the upper level of the adult dietary recommended intake induces detectable but transient changes in healthy adults
    Magdalena Araya
    Institute of Nutrition and Food Technology, University of Chile INTA
    J Nutr 135:2367-71. 2005
    ..We conclude that copper administered as described induced a transient, mild, but significant elevation of aminotransferases...
  65. ncbi Acquisition of visuomotor abilities and intellectual quotient in children aged 4-10 years: relationship with micronutrient nutritional status
    Horacio F González
    Instituto de Desarrollo e Investigaciones Pediátricas, Centro Asociado a la Comisión de Investigaciones Científicas de la Provincia de Buenos Aires, Hospital de Niños Sor María Ludovica, La Plata, Argentina
    Biol Trace Elem Res 120:92-101. 2007
    ..The fact that children with abnormal VMI presented low mean serum copper and ferritin concentrations could indicate that copper and iron deficiencies in this sample could be related with visuomotor abilities...
  66. ncbi Bioavailability of microencapsulated ferrous sulfate in milk
    Manuel Olivares
    Nutrition 18:285-6. 2002