V Mericq

Summary

Affiliation: Universidad de Chile
Country: Chile

Publications

  1. ncbi request reprint Longitudinal changes in insulin sensitivity and secretion from birth to age three years in small- and appropriate-for-gestational-age children
    V Mericq
    Institute of Maternal and Child Research, University of Chile, Santiago, Chile
    Diabetologia 48:2609-14. 2005
  2. ncbi request reprint Longitudinal changes in insulin-like growth factor-I, insulin sensitivity, and secretion from birth to age three years in small-for-gestational-age children
    German Iniguez
    Institute of Maternal and Child Research, Faculty of Medicine, University of Chile, 1027 Santiago, Chile
    J Clin Endocrinol Metab 91:4645-9. 2006
  3. pmc Effect of the parental origin of the X-chromosome on the clinical features, associated complications, the two-year-response to growth hormone (rhGH) and the biochemical profile in patients with turner syndrome
    Francisco Alvarez-Nava
    Unidad de Endocrinologia Pediatrica, Hospital de Clinicas Caracas, Caracas, Venezuela
    Int J Pediatr Endocrinol 2013:10. 2013
  4. pmc Latin American consensus: children born small for gestational age
    Margaret C S Boguszewski
    Department of Pediatrics, Hospital de Clinicas, Federal University of Parana, Curitiba, Brazil
    BMC Pediatr 11:66. 2011
  5. ncbi request reprint Relationship between nocturnal growth hormone concentrations, serum IGF-I/IGFBP-3 levels, insulin sensitivity and GH receptor allelic variant in small for gestational age children
    Veronica Mericq
    Faculty of Medicine, Institute of Maternal and Child Research, University of Chile, Santiago, Chile
    Horm Res 68:132-8. 2007
  6. ncbi request reprint [Effectiveness of Leuprolide acetate therapy every three months in central precocious puberty]
    M Verónica Mericq G
    Departamento de Pediatria, Unidad de Endocrinologia, Clinica Las Condes, Chile
    Rev Med Chil 134:821-6. 2006
  7. ncbi request reprint Low birth weight and endocrine dysfunction in postnatal life
    Veronica Mericq
    Institute of Maternal and Child Research, Faculty of Medicine, University of Chile, Santiago
    Pediatr Endocrinol Rev 4:3-14. 2006
  8. ncbi request reprint Prematurity and insulin sensitivity
    V Mericq
    Institute of Maternal and Child Research, Faculty of Medicine, University of Chile, Santiago
    Horm Res 65:131-6. 2006
  9. ncbi request reprint Ala54Thr polymorphism of the fatty acid-binding protein 2 gene (intestinal-type FABP) is associated with changes in insulin sensitivity in SGA pubertal girls
    Veronica Mericq
    Institute of Maternal and Child Research, Faculty ofMedicine, University of Chile, Santiago
    J Pediatr Endocrinol Metab 21:117-25. 2008
  10. doi request reprint Expression and activity of 11beta-hydroxysteroid dehydrogenase type 1 enzyme in subcutaneous and visceral adipose tissue of prepubertal children
    Veronica Mericq
    Institute of Maternal and Child Research, Faculty of Medicine, University of Chile, Santiago, Chile
    Horm Res 71:89-93. 2009

Collaborators

Detail Information

Publications41

  1. ncbi request reprint Longitudinal changes in insulin sensitivity and secretion from birth to age three years in small- and appropriate-for-gestational-age children
    V Mericq
    Institute of Maternal and Child Research, University of Chile, Santiago, Chile
    Diabetologia 48:2609-14. 2005
    ..Insulin resistance and type 2 diabetes risk in human subjects who were small-for-gestational-age (SGA) at birth may be a consequence of rapid early postnatal weight gain...
  2. ncbi request reprint Longitudinal changes in insulin-like growth factor-I, insulin sensitivity, and secretion from birth to age three years in small-for-gestational-age children
    German Iniguez
    Institute of Maternal and Child Research, Faculty of Medicine, University of Chile, 1027 Santiago, Chile
    J Clin Endocrinol Metab 91:4645-9. 2006
    ..In contrast, greater insulin secretion is related to infancy height gains. We hypothesized that IGF-I levels could be differentially related to gains in length and weight and also differentially related to IR and insulin secretion...
  3. pmc Effect of the parental origin of the X-chromosome on the clinical features, associated complications, the two-year-response to growth hormone (rhGH) and the biochemical profile in patients with turner syndrome
    Francisco Alvarez-Nava
    Unidad de Endocrinologia Pediatrica, Hospital de Clinicas Caracas, Caracas, Venezuela
    Int J Pediatr Endocrinol 2013:10. 2013
    ..The objective of this study was to determine the influence of the parental origin of the X-chromosome on phenotypic variability, response to rhGH and on the biochemical profile of TS patients...
  4. pmc Latin American consensus: children born small for gestational age
    Margaret C S Boguszewski
    Department of Pediatrics, Hospital de Clinicas, Federal University of Parana, Curitiba, Brazil
    BMC Pediatr 11:66. 2011
    ..Leading experts in pediatric endocrinology throughout Latin America established working groups in order to discuss key challenges regarding the evaluation and management of children born SGA and ultimately develop a consensus statement...
  5. ncbi request reprint Relationship between nocturnal growth hormone concentrations, serum IGF-I/IGFBP-3 levels, insulin sensitivity and GH receptor allelic variant in small for gestational age children
    Veronica Mericq
    Faculty of Medicine, Institute of Maternal and Child Research, University of Chile, Santiago, Chile
    Horm Res 68:132-8. 2007
    ..These results suggest that the GHR allelic variant does not play a significant role in the regulation of GH-IGF-I/BP3 axis or in insulin sensitivity in prepubertal LBW children...
  6. ncbi request reprint [Effectiveness of Leuprolide acetate therapy every three months in central precocious puberty]
    M Verónica Mericq G
    Departamento de Pediatria, Unidad de Endocrinologia, Clinica Las Condes, Chile
    Rev Med Chil 134:821-6. 2006
    ..The efficacy of treatment with a long acting agonist analogue of the gonadotropin releasing hormone (aLHRH) has been well demonstrated...
  7. ncbi request reprint Low birth weight and endocrine dysfunction in postnatal life
    Veronica Mericq
    Institute of Maternal and Child Research, Faculty of Medicine, University of Chile, Santiago
    Pediatr Endocrinol Rev 4:3-14. 2006
    ..In this paper the factors that participate in the programming of the fetus and infants that lead to endocrine dysfunction in postnatal life is reviewed...
  8. ncbi request reprint Prematurity and insulin sensitivity
    V Mericq
    Institute of Maternal and Child Research, Faculty of Medicine, University of Chile, Santiago
    Horm Res 65:131-6. 2006
    ....
  9. ncbi request reprint Ala54Thr polymorphism of the fatty acid-binding protein 2 gene (intestinal-type FABP) is associated with changes in insulin sensitivity in SGA pubertal girls
    Veronica Mericq
    Institute of Maternal and Child Research, Faculty ofMedicine, University of Chile, Santiago
    J Pediatr Endocrinol Metab 21:117-25. 2008
    ..The aim of this study was to evaluate the association of Ala54 Thr polymorphism of the FABP2 gene with insulin sensitivity in pubertal girls born small for gestational age (SGA)...
  10. doi request reprint Expression and activity of 11beta-hydroxysteroid dehydrogenase type 1 enzyme in subcutaneous and visceral adipose tissue of prepubertal children
    Veronica Mericq
    Institute of Maternal and Child Research, Faculty of Medicine, University of Chile, Santiago, Chile
    Horm Res 71:89-93. 2009
    ..Ligand availability to the glucocorticoid receptor is controlled by isoforms of 11beta-hydroxysteroid dehydrogenase (11beta-HSD) which converts endogenous cortisone to active cortisol...
  11. ncbi request reprint XVIII Annual Meeting of the Sociedad Latinoamericana De Endocrinologia Pediatrica (SLEP)
    Alejandro Martinez
    Department of Pediatrics, Faculty of Medicine, Catholic University and Verónica Mericq, Institute of Maternal and Child Research, Faculty of Medicine, University of Chile
    Pediatr Endocrinol Rev 4:366-7. 2007
  12. doi request reprint Prematurity and insulin sensitivity
    V Mericq
    Institute of Maternal and Child Research, Faculty of Medicine, University of de Chile, Santa Rosa 1234, 2 Piso, Casilla 226 3 Santiago, Chile
    J Endocrinol Invest 34:145-9. 2011
    ..Moreover, we add some recent data on how nutritional intervention could modify these risks...
  13. ncbi request reprint Differences in body composition and energy expenditure in prepubertal children born term or preterm appropriate or small for gestational age
    Veronica Mericq
    Institute of Maternal and Child Research, Faculty of Medicine, University of Chile, Santiago, Chile
    J Pediatr Endocrinol Metab 22:1041-50. 2009
    ..This difference might be a consequence of different timing in the exposure to intrauterine nutritional deficiency...
  14. doi request reprint Comparison of three doses of leuprolide acetate in the treatment of central precocious puberty: preliminary results
    Veronica Mericq
    Institute of Maternal and Child Research, Faculty of Medicine, University of Chile, Casilla 226 3, Santiago, Chile
    Clin Endocrinol (Oxf) 71:686-90. 2009
    ..The goal of our study was to compare the efficacy of three leuprolide acetate (LA) preparations, suppressing gonadotropin secretion in patients with CPP...
  15. doi request reprint Leuprolide acetate gonadotrophin response patterns during female puberty
    A Martinez-Aguayo
    Paediatric Department, School of Medicine, Pontificia Universidad Catolica de Chile, Santiago, Chile
    Clin Endocrinol (Oxf) 72:489-95. 2010
    ..To assess normative data and the usefulness of spontaneous and LHRH analogue-stimulated serum LH and FSH levels measured by immunoradiometric assays (IRMA) in the evaluation of normal puberty...
  16. ncbi request reprint Comparison of leptin levels, body composition and insulin sensitivity and secretion by OGTT in healthy, early pubertal girls born at either appropriate- or small-for-gestational age
    A Martinez-Aguayo
    Institute of Maternal and Child Research IDIMI, Faculty of Medicine, University of Chile, Santiago, Chile
    Clin Endocrinol (Oxf) 67:526-32. 2007
    ..Small for gestational age (SGA) has been associated with decreased insulin sensitivity (IS). A possible mechanism is the postnatal development of a metabolically disadvantageous body composition (BC)...
  17. ncbi request reprint Comparison of clinical, ultrasonographic, and biochemical differences at the beginning of puberty in healthy girls born either small for gestational age or appropriate for gestational age: preliminary results
    M I Hernandez
    Institute of Maternal and Child Research, University of Chile, Casilla 226 3, Santiago, Chile
    J Clin Endocrinol Metab 91:3377-81. 2006
    ..There are limited and controversial data concerning puberty characteristics in girls born small for gestational age (SGA)...
  18. doi request reprint Differences in expression and activity of 11beta-hydroxysteroid dehydrogenase type 1 and 2 in human placentas of term pregnancies according to birth weight and gender
    V Mericq
    Institute of Maternal and Child Research, Faculty of Medicine, University of Chile, Santa Rosa 1234, 2 degrees Piso, Casilla 226 3, Santiago, Chile
    Eur J Endocrinol 161:419-25. 2009
    ....
  19. doi request reprint Cortisol hyporesponsiveness to the low dose ACTH test is a frequent finding in a pediatric population with type 1 diabetes mellitus
    X Gaete
    Institute of Maternal and Child Research, Pediatric Endocrinology Unit, Faculty of Medicine, University of Chile, Santiago, Chile
    Pediatr Diabetes 14:429-34. 2013
    ..In adults with type 1 diabetes mellitus (DM1), a 25% of risk of hypocortisolism has been found through a low dose ACTH test with negative antibodies suggesting other causes of hypothalamic-pituitary-adrenal axis dysfunction...
  20. ncbi request reprint The effects of beta 1-adrenergic blockade on the growth response to growth hormone (GH)-releasing hormone therapy in GH-deficient children
    F Cassorla
    Institute of Maternal and Child Research, University of Chile, School of Medicine, Santiago
    J Clin Endocrinol Metab 80:2997-3001. 1995
    ..05). This is the first demonstration that alteration of neurotransmitter action can enhance the therapeutic response to a hypothalamic releasing factor...
  21. ncbi request reprint Effects of eight months treatment with graded doses of a growth hormone (GH)-releasing peptide in GH-deficient children
    V Mericq
    Institute of Maternal and Child Research, University of Chile, Santiago, Chile
    J Clin Endocrinol Metab 83:2355-60. 1998
    ..Thus GHRP-2 is well tolerated and is able to stimulate GH secretion. Formulations or routes of administration that allow for a longer duration of action will likely be needed to use GHRP-2 in therapy...
  22. doi request reprint Relationship between insulin sensitivity and IGF-I sensitivity in low birth weight prepubertal children
    Rossana Roman
    Institute of Maternal and Child Research, University of Chile, Santiago, Chile
    Horm Res 70:73-8. 2008
    ..Aim: We postulate that some low birth weight (LBW) children may have decreased sensitivity to both insulin and IGF-I...
  23. ncbi request reprint [Visceral adiposity and its association with serum lipids in female obese teenagers]
    Daniela Neri
    Instituto de Nutricion y Tecnologia de los Alimentos, Universidad de Chile, Santiago, Chile
    Rev Med Chil 135:294-300. 2007
    ..Aim: To study the association between visceral or external body measurements of adiposity with blood lipids, glucose and insulin levels, in obese female adolescents...
  24. ncbi request reprint Fasting and post-glucose ghrelin levels in SGA infants: relationships with size and weight gain at one year of age
    German Iniguez
    Institute of Maternal and Child Research, University of Chile, Santiago, Chile
    J Clin Endocrinol Metab 87:5830-3. 2002
    ....
  25. pmc Mild fasting hyperglycemia in children: high rate of glucokinase mutations and some risk of developing type 1 diabetes mellitus
    Ethel Codner
    Institute of Maternal and Child Research IDIMI, School of Medicine, University of Chile, Santiago, Chile
    Pediatr Diabetes 10:382-8. 2009
    ..Incidental hyperglycemia in children generates concern about the presence of preclinical type 1 diabetes mellitus (T1DM)...
  26. doi request reprint [Ultrasound measurements of intra-abdominal adiposity and factors associated with cardiovascular risk in obese children]
    Marcela Reyes
    Instituto de Nutricion y Tecnologia de los Alimentos, Universidad de Chile, Santiago, Chile
    Rev Med Chil 138:152-9. 2010
    ..Cardiovascular risk factors are commonly present in obese children...
  27. ncbi request reprint A new DAX-1 mutation in a family with a case of neonatal adrenal insufficiency and a sibling with adrenal hypoplasia and sudden death at 3 years of age
    Veronica Mericq
    Institute of Maternal and Child Research, Faculty of Medicine, University of Chile, Santiago
    J Pediatr Endocrinol Metab 20:1039-43. 2007
    ..The mother was heterozygous for this mutation. In conclusion, a novel DAX-1 mutation was detected in two family members with different phenotype: one live infant with adrenal hypoplasia, his mother, and probably his dead brother...
  28. ncbi request reprint Adiponectin levels in the first two years of life in a prospective cohort: relations with weight gain, leptin levels and insulin sensitivity
    German Iniguez
    Institute of Maternal and Child Research, Faculty of Medicine, University of Chile, PO Box 226 3, Santiago, Chile
    J Clin Endocrinol Metab 89:5500-3. 2004
    ..004). In conclusion, fall in serum adiponectin levels during the first two years of life were related to increasing age and greater weight gain SGA infants, but were unrelated to insulin sensitivity...
  29. ncbi request reprint [Results of a multidisciplinary and intensified treatment program for type 1 Diabetes Mellitus in a Chilean Public Hospital]
    Ethel Codner
    Instituto de Investigaciones, Materno Infantil IDIMI, Facultad de Medicina, Universidad de Chile, Hospital Clinico San Borja Arriaran, Servicio de Salud Santiago Centro, Santiago, Chile
    Rev Med Chil 131:857-64. 2003
    ..During the last decade, the importance of glycemic control in the prevention of the microvascular complications of type 1 Diabetes Mellitus (DM1) was clearly demonstrated...
  30. ncbi request reprint Changes in appetite and body weight in response to long-term oral administration of the ghrelin agonist GHRP-2 in growth hormone deficient children
    Veronica Mericq
    Institute of Maternal and Child Research, University of Chile, Santiago, Chile
    J Pediatr Endocrinol Metab 16:981-5. 2003
    ..5 SDS). These results suggest that at a dose of 900 microg/kg b.i.d., GHRP-2 appears to have a transient stimulatory effect on appetite, but does not have a chronic clinically significant effect on BMI in children with GH deficiency...
  31. ncbi request reprint YqTER deletion causes arrest of spermatogenesis in early puberty
    Andrea Castro
    Institute of Maternal and Child Research, School of Medicine, University of Chile, Santiago, Chile
    J Pediatr Endocrinol Metab 17:1675-8. 2004
    ..The present report suggests that Y chromosome deletions including AZFb and AZFc regions may cause spermatogenic arrest in early puberty...
  32. ncbi request reprint [Clinical and molecular study of Chilean patients with McCune-Albright syndrome]
    R Roman
    Instituto de Investigaciones Materno Infantil, Facultad de Medicina, Universidad de Chile, Hospital San Borja Arriaran, Luis Calvo Mackenna, Hospital Clínico P Universidad Católica, Santiago, Chile
    Rev Med Chil 129:1365-72. 2001
    ..McCune-Albright Syndrome (MAS) is characterized by precocious puberty, "cafe au lait" skin lesions and polyostotic fibrous dysplasia. It is caused by 4 post-zygotic mutations of G alpha s protein with a mosaic distribution...
  33. ncbi request reprint Determinants of insulin sensitivity and secretion in very-low-birth-weight children
    Rodrigo A Bazaes
    Institute of Maternal and Child Research, Faculty of Medicine, University of Chile, Santiago 8360160, Chile
    J Clin Endocrinol Metab 89:1267-72. 2004
    ..Our findings in a cohort of VLBW prepubertal children indicate that growth in utero as well as postnatal growth rates are independent determinants of subsequent insulin sensitivity and secretion...
  34. ncbi request reprint Effects of treatment with GH alone or in combination with LHRH analog on bone mineral density in pubertal GH-deficient patients
    Veronica Mericq
    Institute of Maternal and Child Research, University of Chile, Santiago, Chile
    J Clin Endocrinol Metab 87:84-9. 2002
    ..These results indicate that delaying puberty with LHRH-A in GH-deficient patients treated with GH diminishes transient bone mineralization but does not appear to have a permanent impact on BMD...
  35. doi request reprint Insulin resistance markers in children
    Francisca Eyzaguirre
    Institute of Maternal and Child Research, University of Chile, Santiago, Chile
    Horm Res 71:65-74. 2009
    ....
  36. pmc Differences in Expression, Content, and Activity of 11β-HSD1 in Adipose Tissue between Obese Men and Women
    A Torres
    Institute of Maternal and Child Research, Faculty of Medicine, University of Chile, Casilla 226 3, 8360160 Santiago, Chile
    ISRN Endocrinol 2012:787201. 2012
    ....
  37. doi request reprint Impact of being born small for gestational age on onset and progression of puberty
    Maria Isabel Hernández
    Institute of Maternal and Child Research, Faculty of Medicine, University of Chile, Casilla 226 3, Santiago, Chile
    Best Pract Res Clin Endocrinol Metab 22:463-76. 2008
    ..This chapter will discuss the factors that could influence pubertal development in children born SGA and the information reported to date...
  38. ncbi request reprint Adrenarche in Prader-Willi syndrome appears not related to insulin sensitivity and serum adiponectin
    Nancy Unanue
    Institute of Maternal and Child Research, Faculty of Medicine, Santiago, Chile
    Horm Res 67:152-8. 2007
    ..05). In conclusion, a higher proportion of premature adrenarche in our PW patients was observed, which was not explained by differences in insulin sensitivity or plasma levels of adipokines and IGF-I...
  39. doi request reprint Nutrition, child growth, and chronic disease prevention
    Ricardo Uauy
    Institute of Nutrition and Food Technology INTA, University of Chile, Santiago, Chile
    Ann Med 40:11-20. 2008
    ..These actions should contribute in the prevention and control of obesity in childhood and thus help prevent NRCDs in future generations of adults...
  40. doi request reprint Familial tumoral calcinosis caused by a novel FGF23 mutation: response to induction of tubular renal acidosis with acetazolamide and the non-calcium phosphate binder sevelamer
    Juan Javier Lammoglia
    Institute of Maternal and Child Research, Faculty of Medicine, University of Chile, Santiago, Chile
    Horm Res 71:178-84. 2009
    ..Sequencing analysis revealed a novel homozygous FGF23 missense mutation (c.367G>T, p.Gly123Trp) in both siblings while the parents were carriers of the mutation...
  41. ncbi request reprint Pubertal development in girls born small for gestational age
    Maria Isabel Hernández
    Institute of Maternal and Child Research, Faculty of Medicine, University of Chile, Santiago, Chile
    J Pediatr Endocrinol Metab 21:201-8. 2008
    ..This review attempts to discuss the factors that could influence pubertal development in girls born small for gestational age and the information reported to date...