Anibal J Llanos

Summary

Affiliation: Universidad de Chile
Country: Chile

Publications

  1. pmc Long-term exposure to high-altitude chronic hypoxia during gestation induces neonatal pulmonary hypertension at sea level
    Emilio A Herrera
    Programa de Fisiopatología, Instituto de Ciencias Biomedicas, Facultad de Medicina, Universidad de Chile Avda Salvador 486, Providencia, CP 6640871, Santiago, Chile
    Am J Physiol Regul Integr Comp Physiol 299:R1676-84. 2010
  2. pmc Role of the α-adrenergic system in femoral vascular reactivity in neonatal llamas and sheep: a comparative study between highland and lowland species
    Fernando A Moraga
    Laboratorio de Fisiología y Fisiopatología del Desarrollo, Programa de Fisiopatología, ICBM, Facultad de Medicina, Universidad de Chile, Santiago, Chile
    Am J Physiol Regul Integr Comp Physiol 301:R1153-60. 2011
  3. doi request reprint The heme oxygenase-carbon monoxide system in the regulation of cardiorespiratory function at high altitude
    Anibal J Llanos
    Unidad de Fisiología y Fisiopatología Perinatal, Programa de Fisiopatología, Instituto de Ciencias Biomedicas, Facultad de Medicina, Universidad de Chile, Santiago, Chile
    Respir Physiol Neurobiol 184:186-91. 2012
  4. doi request reprint Fetal and postnatal pulmonary circulation in the Alto Andino
    A J Llanos
    Facultad de Medicina, Universidad de Chile, Santiago, Chile
    Placenta 32:S100-3. 2011
  5. ncbi request reprint Evolving in thin air--lessons from the llama fetus in the altiplano
    Anibal J Llanos
    Laboratorio de Fisiología y Fisiopatología del Desarrollo, Programa de Fisiopatología, Instituto de Ciencias Biomedicas ICBM, Facultad de Medicina, Universidad de Chile, Santiago, Chile
    Respir Physiol Neurobiol 158:298-306. 2007
  6. ncbi request reprint Vasodilator tone in the llama fetus: the role of nitric oxide during normoxemia and hypoxemia
    Emilia M Sanhueza
    Programa de Fisiopatología, Instituto de Ciencias Biomedicas, Facultad de Medicina, Universidad de Chile, Casilla 16038, Santiago 9, Chile
    Am J Physiol Regul Integr Comp Physiol 289:R776-83. 2005
  7. ncbi request reprint High-altitude chronic hypoxia during gestation and after birth modifies cardiovascular responses in newborn sheep
    Emilio A Herrera
    Laboratorio de Fisiología y Fisiopatología del Desarrollo, Programa de Fisiopatología, Instituto de Ciencias Biomedicas, Facultad de Medicina, Universidad de Chile, Santiago, Chile
    Am J Physiol Regul Integr Comp Physiol 292:R2234-40. 2007
  8. ncbi request reprint Carbon monoxide: a novel pulmonary artery vasodilator in neonatal llamas of the Andean altiplano
    Emilio A Herrera
    Programa de Fisiopatología, ICBM, Facultad de Medicina, Universidad de Chile, Santiago, Chile
    Cardiovasc Res 77:197-201. 2008
  9. pmc Nitric oxide plays a role in the regulation of adrenal blood flow and adrenocorticomedullary functions in the llama fetus
    Raquel A Riquelme
    Departamento de Bioquimica y Biologia Molecular, Facultad de Ciencias Quimicas y Farmaceuticas, Universidad de Chile, Santiago, Chile
    J Physiol 544:267-76. 2002
  10. ncbi request reprint The fetal llama versus the fetal sheep: different strategies to withstand hypoxia
    Anibal J Llanos
    Laboratorio de Fisiología y Fisiopatología del Desarrollo, Programa de Fisiopatología, Instituto de Ciencias Biomedicas, Facultad de Medicina, Universidad de Chile, Santiago, Chile
    High Alt Med Biol 4:193-202. 2003

Collaborators

Detail Information

Publications19

  1. pmc Long-term exposure to high-altitude chronic hypoxia during gestation induces neonatal pulmonary hypertension at sea level
    Emilio A Herrera
    Programa de Fisiopatología, Instituto de Ciencias Biomedicas, Facultad de Medicina, Universidad de Chile Avda Salvador 486, Providencia, CP 6640871, Santiago, Chile
    Am J Physiol Regul Integr Comp Physiol 299:R1676-84. 2010
    ..82 ± 0.26 vs. 2.22 ± 0.44) and carbon monoxide production (all P < 0.05). Postnatal pulmonary hypertension induced by 70% of pregnancy at HA promotes cardiopulmonary remodeling that persists at sea level...
  2. pmc Role of the α-adrenergic system in femoral vascular reactivity in neonatal llamas and sheep: a comparative study between highland and lowland species
    Fernando A Moraga
    Laboratorio de Fisiología y Fisiopatología del Desarrollo, Programa de Fisiopatología, ICBM, Facultad de Medicina, Universidad de Chile, Santiago, Chile
    Am J Physiol Regul Integr Comp Physiol 301:R1153-60. 2011
    ....
  3. doi request reprint The heme oxygenase-carbon monoxide system in the regulation of cardiorespiratory function at high altitude
    Anibal J Llanos
    Unidad de Fisiología y Fisiopatología Perinatal, Programa de Fisiopatología, Instituto de Ciencias Biomedicas, Facultad de Medicina, Universidad de Chile, Santiago, Chile
    Respir Physiol Neurobiol 184:186-91. 2012
    ..The gasotransmitters NO and CO are important in the regulation of the pulmonary vascular function at high altitudes in both high altitude acclimatized species, such as the sheep, and high altitude adapted species, such as the llama...
  4. doi request reprint Fetal and postnatal pulmonary circulation in the Alto Andino
    A J Llanos
    Facultad de Medicina, Universidad de Chile, Santiago, Chile
    Placenta 32:S100-3. 2011
    ..The rise in pulmonary arterial pressure was more marked in the sheep than in the llama. The llama pulmonary dilator strategy may provide insights into new treatments for pulmonary arterial hypertension of the neonate and adult...
  5. ncbi request reprint Evolving in thin air--lessons from the llama fetus in the altiplano
    Anibal J Llanos
    Laboratorio de Fisiología y Fisiopatología del Desarrollo, Programa de Fisiopatología, Instituto de Ciencias Biomedicas ICBM, Facultad de Medicina, Universidad de Chile, Santiago, Chile
    Respir Physiol Neurobiol 158:298-306. 2007
    ..These strategies may have evolved to prevent hypoxic injury to the brain or other organs in the face of the persistent hypobaric hypoxia of life in the Andean altiplano...
  6. ncbi request reprint Vasodilator tone in the llama fetus: the role of nitric oxide during normoxemia and hypoxemia
    Emilia M Sanhueza
    Programa de Fisiopatología, Instituto de Ciencias Biomedicas, Facultad de Medicina, Universidad de Chile, Casilla 16038, Santiago 9, Chile
    Am J Physiol Regul Integr Comp Physiol 289:R776-83. 2005
    ....
  7. ncbi request reprint High-altitude chronic hypoxia during gestation and after birth modifies cardiovascular responses in newborn sheep
    Emilio A Herrera
    Laboratorio de Fisiología y Fisiopatología del Desarrollo, Programa de Fisiopatología, Instituto de Ciencias Biomedicas, Facultad de Medicina, Universidad de Chile, Santiago, Chile
    Am J Physiol Regul Integr Comp Physiol 292:R2234-40. 2007
    ..These responses determined in intrauterine life and early after birth could be adaptive to chronic hypoxia in the Andean altiplano...
  8. ncbi request reprint Carbon monoxide: a novel pulmonary artery vasodilator in neonatal llamas of the Andean altiplano
    Emilio A Herrera
    Programa de Fisiopatología, ICBM, Facultad de Medicina, Universidad de Chile, Santiago, Chile
    Cardiovasc Res 77:197-201. 2008
    ..To study the nitric oxide (NO) and carbon monoxide roles in the regulation of the pulmonary circulation in lowland and highland newborn sheep and llamas...
  9. pmc Nitric oxide plays a role in the regulation of adrenal blood flow and adrenocorticomedullary functions in the llama fetus
    Raquel A Riquelme
    Departamento de Bioquimica y Biologia Molecular, Facultad de Ciencias Quimicas y Farmaceuticas, Universidad de Chile, Santiago, Chile
    J Physiol 544:267-76. 2002
    ..These data support the hypothesis that nitric oxide has important roles in the regulation of adrenal blood flow and adrenal corticomedullary functions during normoxaemia and hypoxaemia functions in the late gestation llama fetus...
  10. ncbi request reprint The fetal llama versus the fetal sheep: different strategies to withstand hypoxia
    Anibal J Llanos
    Laboratorio de Fisiología y Fisiopatología del Desarrollo, Programa de Fisiopatología, Instituto de Ciencias Biomedicas, Facultad de Medicina, Universidad de Chile, Santiago, Chile
    High Alt Med Biol 4:193-202. 2003
    ..These results suggest that the llama fetus responds to acute hypoxia with hypometabolism. How this reduction in metabolism is produced and how the cells are preserved during this condition remain to be elucidated...
  11. pmc Regional brain blood flow and cerebral hemispheric oxygen consumption during acute hypoxaemia in the llama fetus
    Anibal J Llanos
    Laboratorio de Fisiología y Fisiopatología del Desarrollo, Programa de Fisiopatología, Instituto de Ciencias Biomedicas, Facultad de Medicina, Universidad de Chile, Santiago, Chile
    J Physiol 538:975-83. 2002
    ..Rather, the data show that in the llama fetus, a reduction in cerebral hemispheric metabolism occurs during acute hypoxaemia...
  12. ncbi request reprint Sildenafil reverses hypoxic pulmonary hypertension in highland and lowland newborn sheep
    Emilio A Herrera
    Program in Pathophysiology, University of Chile, CP 6640871, Santiago, Chile
    Pediatr Res 63:169-75. 2008
    ..The distal pulmonary arteries showed an increased wall thickness in HLNB. Our results showed that HLNB are more sensitive to sildenafil and therefore could be useful for treatment of pulmonary hypertension in high-altitude neonates...
  13. pmc The role of neuropeptide Y in the ovine fetal cardiovascular response to reduced oxygenation
    Emilia M Sanhueza
    Programa de Fisiopatología, Instituto de Ciencias Biomédicas ICMB, Facultad de Medicina and Centro Internacional de Estudios Andinos INCAS, Universidad de Chile, Chile
    J Physiol 546:891-901. 2003
    ..These results support a greater role for NPY in mediating the fetal cardiovascular responses to acute asphyxia than to acute moderate hypoxaemia...
  14. pmc Fetal brain hypometabolism during prolonged hypoxaemia in the llama
    German Ebensperger
    Programa de Fisiopatología, Instituto de Ciencias Biomedicas, Facultad de Medicina, Universidad de Chile, Santiago
    J Physiol 567:963-75. 2005
    ....
  15. doi request reprint Store-operated channels in the pulmonary circulation of high- and low-altitude neonatal lambs
    Daniela Parrau
    Laboratorios de Fisiología y Fisiopatología del Desarrollo, y de Bioquímica y Biología Molecular de la Hipoxia, Programa de Fisiopatología, Instituto de Ciencias Biomedicas ICBM, Facultad de Medicina, Universidad de Chile, Santiago, Chile
    Am J Physiol Lung Cell Mol Physiol 304:L540-8. 2013
    ..Therefore, SOC may contribute to the development of neonatal pulmonary hypertension. We propose SOC channels could be potential targets to treat neonatal pulmonary hypertension...
  16. doi request reprint Circadian rhythms in the fetus
    Maria Seron-Ferre
    Programa de Fisiopatología, Instituto de Ciencias Biomedicas, Universidad de Chile, Chile
    Mol Cell Endocrinol 349:68-75. 2012
    ..Following birth, it will allow for postnatal integration of the scattered fetal circadian clocks into an adult-like circadian system commanded by the SCN...
  17. ncbi request reprint Use of fetal biometry to determine fetal age in late pregnancy in llamas
    Emilio A Herrera
    Programa de Fisiopatología, Facultad de Medicina, Instituto de Ciencias Biomedicas, Universidad de Chile, Av Salvador 486, Providencia, Santiago, Chile eherrera2machi med uchile cl
    Anim Reprod Sci 74:101-9. 2002
    ....
  18. pmc Evidence of a role for melatonin in fetal sheep physiology: direct actions of melatonin on fetal cerebral artery, brown adipose tissue and adrenal gland
    Claudia Torres-Farfan
    Instituto de Ciencias Biomedicas, Facultad de Medicina, Universidad de Chile, Santiago, Chile
    J Physiol 586:4017-27. 2008
    ..These direct inhibitory responses to melatonin support a role for melatonin in fetal physiology, which we propose prevents major contraction of cerebral vessels, restrains cortisol release and restricts BAT lypolysis during fetal life...
  19. ncbi request reprint Hypoxia-related lipid peroxidation: evidences, implications and approaches
    Claus Behn
    Laboratorio de Ambientes Extremos, Programa de Fisiologia y Biofisica, ICBM, Facultad de Medicina, Universidad de Chile Independencia 1027, Independencia, Santiago, Chile
    Respir Physiol Neurobiol 158:143-50. 2007
    ..A need for antioxidant intervention, however, should be weighed against the ROS requirement for triggering adaptive processes in response to an increased demand of oxygen...