Marcela A Hermoso


Affiliation: Universidad de Chile
Country: Chile


  1. De la Fuente M, MacDonald T, Hermoso M. The IL-33/ST2 axis: Role in health and disease. Cytokine Growth Factor Rev. 2015;26:615-23 pubmed publisher
    ..The IL-33/ST2 axis is involved in the pathogenesis of atopic and autoimmune diseases, cancer, and central nervous system disorders. Here, we review recent findings on the role of the IL-33/ST2 axis in health and disease. ..
  2. De la Fuente M, Franchi L, Araya D, Díaz Jiménez D, Olivares M, Alvarez Lobos M, et al. Escherichia coli isolates from inflammatory bowel diseases patients survive in macrophages and activate NLRP3 inflammasome. Int J Med Microbiol. 2014;304:384-92 pubmed publisher
    ..Invasiveness of intracellular E. coli strains into the intestinal mucosa and IL-1? production may contribute to CD and UC pathogenesis. ..
  3. Díaz Jiménez D, De la Fuente M, Dubois Camacho K, Landskron G, Fuentes J, Perez T, et al. Soluble ST2 is a sensitive clinical marker of ulcerative colitis evolution. BMC Gastroenterol. 2016;16:103 pubmed publisher
    ..Consecutive sST2 measurement to follow changes in inflammatory activity of UC patients who respond or not to treatment identifies sST2, like FC, as a useful biomarker in predicting clinical outcome of UC patients. ..
  4. Díaz Jiménez D, Núñez L, De la Fuente M, Dubois Camacho K, Sepulveda H, Montecino M, et al. A functional IL1RL1 variant regulates corticosteroid-induced sST2 expression in ulcerative colitis. Sci Rep. 2017;7:10180 pubmed publisher
    ..Our data indicate that IL1RL1 SNPs rs6543115(C) confer susceptibility to UC and is contained in the GRE, which may modulate glucocorticoid-induced sST2 expression. ..
  5. Dubois Camacho K, Ottum P, Franco Muñoz D, De la Fuente M, Torres Riquelme A, Díaz Jiménez D, et al. Glucocorticosteroid therapy in inflammatory bowel diseases: From clinical practice to molecular biology. World J Gastroenterol. 2017;23:6628-6638 pubmed publisher
    ..This thorough analysis of current clinical and biomedical literature may help guide physicians in determining a course of treatment for IBDs patients and identifies important areas needing further study. ..