Francisco Lopez-Kostner

Summary

Country: Chile

Publications

  1. ncbi request reprint Gene symbol: APC. Disease: Adenomatous polyposis coli
    Francisco Lopez-Kostner
    Clinica Las Condes, Unidad de Coloproctologia, Lo Fontecilla, 441, 7591046 Las Condes, Santiago, Chile
    Hum Genet 124:316. 2008
  2. doi request reprint [A screening program for colorectal cancer in Chilean subjects aged fifty years or more]
    Francisco Lopez-Kostner
    Unidad de Coloproctologia, Clinica Las Condes, Santiago, Chile
    Rev Med Chil 140:281-6. 2012
  3. doi request reprint [Homozygous germline mutation in MUTYH gene in familial adenomatous polyposis]
    Karin Alvarez
    Laboratorio de Oncología y Genética Molecular, Unidad de Coloproctologia, Clinica Las Condes, Santiago, Chile
    Rev Med Chil 140:1457-63. 2012
  4. doi request reprint [Lynch syndrome: selection of families by microsatellite instability and immunohistochemistry]
    Ana Maria Wielandt
    Unidad de Coloproctologia, Laboratorio de Oncología y Genética Molecular, Chile
    Rev Med Chil 140:1132-9. 2012
  5. ncbi request reprint [Hereditary colorectal cancer: Molecular analysis of APC and MLH1 genes]
    Felipe Bellolio R
    Departamento de Cirugia Digestiva, Hospital Clinico, Facultad de Medicina, Pontificia Universidad Catolica de Chile, Santiago, Chile
    Rev Med Chil 134:841-8. 2006
  6. ncbi request reprint [Screening colonoscopy among first degree relatives of patients with colorectal carcinoma]
    Francisco Lopez-Kostner
    Departamento de Cirugia Digestiva, Facultad de Medicina, Pontificia Universidad Catolica de Chile, Santiago, Chile
    Rev Med Chil 134:997-1001. 2006
  7. ncbi request reprint Detection of lymphatic micrometastases in patients with stages I and II colorectal cancer: impact on five-year survival
    Udo Kronberg
    Department of Digestive Surgery, Faculty of Medicine, Catholic University of Chile, Santiago, Chile
    Dis Colon Rectum 47:1151-7. 2004
  8. doi request reprint Spectrum of MLH1 and MSH2 mutations in Chilean families with suspected Lynch syndrome
    Karin Alvarez
    Unidad de Coloproctologia, Clinica Las Condes, Santiago, Chile
    Dis Colon Rectum 53:450-9. 2010
  9. pmc Escherichia coli isolates from inflammatory bowel diseases patients survive in macrophages and activate NLRP3 inflammasome
    Marjorie De la Fuente
    Disciplinary Program of Immunology, Institute of Biomedical Sciences, Faculty of Medicine, Universidad de Chile, Santiago, CL 8380453, Chile
    Int J Med Microbiol 304:384-92. 2014
  10. ncbi request reprint Does obesity increase early postoperative complications after laparoscopic colorectal surgery? Results from a single center
    Camila Estay
    Colorectal Unit, Surgery Department, Clinica Las Condes, Lo Fontecilla 441, 7550000, Santiago, Chile
    Surg Endosc 28:2090-6. 2014

Collaborators

  • Roberto Vidal
  • James Church
  • Karin Alvarez
  • Udo Kronberg
  • Marjorie De la Fuente
  • Ana Maria Wielandt
  • Cláudio Wainstein
  • Rodrigo Quera
  • Alejandro J Zárate
  • Pilar Carvallo
  • Eliana Pinto
  • Camila Estay
  • Manuel Alvarez-Lobos
  • María Julieta González
  • Marcela A Hermoso
  • David Díaz-Jiménez
  • Enzo Candia
  • Paulina Orellana
  • Claudia Hurtado
  • Marjorie K De la Fuente
  • Felipe Bellolio R
  • Douglas Golenbock
  • Mauricio Olivares
  • Daniela Araya
  • Mónica Venegas
  • Luigi Franchi
  • Andrés Larach
  • Bernardita Fuentes
  • Magdalena Castro
  • Katya Carrillo
  • Gabriel Nunez
  • Jorge Larach
  • Luis Contreras
  • Carlos Gonzalez
  • Marjorie de la Fuente
  • Cristóbal Suazo
  • Alejandro Corvalan
  • Patricia Langjahr
  • Nancy Farfan
  • Claudio Heine
  • Lucía E Núñez
  • George Pinedo
  • Mario Abedrapo
  • Caroll J Beltrán
  • Montserrat A Hevia
  • Karin P Alvarez
  • Mariana L Acuña
  • Felipe Bellolio
  • Alejandro J Letelier
  • Francisca S León
  • Francisca León G
  • Marjorie De la Fuente L
  • Gonzalo Soto D
  • Pilar Carvallo de S Q
  • Karin Alvarez V
  • Demian A Fullerton M
  • Ignacio Wistuba
  • Gonzalo Soto
  • Alvaro Zuniga
  • Vanessa Miranda
  • Guillermo Marshall
  • Paola Viviani

Detail Information

Publications13

  1. ncbi request reprint Gene symbol: APC. Disease: Adenomatous polyposis coli
    Francisco Lopez-Kostner
    Clinica Las Condes, Unidad de Coloproctologia, Lo Fontecilla, 441, 7591046 Las Condes, Santiago, Chile
    Hum Genet 124:316. 2008
  2. doi request reprint [A screening program for colorectal cancer in Chilean subjects aged fifty years or more]
    Francisco Lopez-Kostner
    Unidad de Coloproctologia, Clinica Las Condes, Santiago, Chile
    Rev Med Chil 140:281-6. 2012
    ..International studies have shown that CCR screening programs based on fecal occult blood test (FOBT) reduce CCR mortality. Aim: To analyze the results from a CCR screening model in people over 50 years...
  3. doi request reprint [Homozygous germline mutation in MUTYH gene in familial adenomatous polyposis]
    Karin Alvarez
    Laboratorio de Oncología y Genética Molecular, Unidad de Coloproctologia, Clinica Las Condes, Santiago, Chile
    Rev Med Chil 140:1457-63. 2012
    ..340T > C, that produces an amino acid change of tyrosine for histidine called p.Y114H. The sister with colorectal cancer was a heterozygous carrier of this mutation...
  4. doi request reprint [Lynch syndrome: selection of families by microsatellite instability and immunohistochemistry]
    Ana Maria Wielandt
    Unidad de Coloproctologia, Laboratorio de Oncología y Genética Molecular, Chile
    Rev Med Chil 140:1132-9. 2012
    ..To increase the rate of identification of mutations, the use of molecular studies as Microsatellite Instability (MSI) and Immunohistochemistry (IHC) in the tumor has been proposed...
  5. ncbi request reprint [Hereditary colorectal cancer: Molecular analysis of APC and MLH1 genes]
    Felipe Bellolio R
    Departamento de Cirugia Digestiva, Hospital Clinico, Facultad de Medicina, Pontificia Universidad Catolica de Chile, Santiago, Chile
    Rev Med Chil 134:841-8. 2006
    ..Among colorectal cancer hereditary variants, two syndromes show a predisposition to the disease based on germline mutations: Familial Adenomatous Polyposis (FAP) and Hereditary Nonpolyposis Colorectal Cancer (HNPCC)...
  6. ncbi request reprint [Screening colonoscopy among first degree relatives of patients with colorectal carcinoma]
    Francisco Lopez-Kostner
    Departamento de Cirugia Digestiva, Facultad de Medicina, Pontificia Universidad Catolica de Chile, Santiago, Chile
    Rev Med Chil 134:997-1001. 2006
    ..First degree relatives of patients with colorectal carcinoma are at a higher risk of having the disease than the general population. Therefore, they should be subjected to screening colonoscopy...
  7. ncbi request reprint Detection of lymphatic micrometastases in patients with stages I and II colorectal cancer: impact on five-year survival
    Udo Kronberg
    Department of Digestive Surgery, Faculty of Medicine, Catholic University of Chile, Santiago, Chile
    Dis Colon Rectum 47:1151-7. 2004
    ..However, the biologic importance of micrometastases remains unclear. This study was designed to determine the impact of micrometastases in five-year survival in patients with Stages I and II colorectal cancer...
  8. doi request reprint Spectrum of MLH1 and MSH2 mutations in Chilean families with suspected Lynch syndrome
    Karin Alvarez
    Unidad de Coloproctologia, Clinica Las Condes, Santiago, Chile
    Dis Colon Rectum 53:450-9. 2010
    ..We report our experience with genetic screening in the diagnosis of Lynch syndrome in Chile, a country previously underserved in the capacity to diagnose hereditary colorectal cancer...
  9. pmc Escherichia coli isolates from inflammatory bowel diseases patients survive in macrophages and activate NLRP3 inflammasome
    Marjorie De la Fuente
    Disciplinary Program of Immunology, Institute of Biomedical Sciences, Faculty of Medicine, Universidad de Chile, Santiago, CL 8380453, Chile
    Int J Med Microbiol 304:384-92. 2014
    ..Invasiveness of intracellular E. coli strains into the intestinal mucosa and IL-1β production may contribute to CD and UC pathogenesis. ..
  10. ncbi request reprint Does obesity increase early postoperative complications after laparoscopic colorectal surgery? Results from a single center
    Camila Estay
    Colorectal Unit, Surgery Department, Clinica Las Condes, Lo Fontecilla 441, 7550000, Santiago, Chile
    Surg Endosc 28:2090-6. 2014
    ..The prevalence of obesity in Chile is increasing, up to 25.1 % in 2010, suggesting that a higher percentage of patients undergoing LCRS will be obese. This study compared POC rates between obese and nonobese patients undergoing LCRS...
  11. doi request reprint [Results or pelvi-perineal rehabilitation in patients with pelvic floor dyssynergia]
    Cláudio Wainstein
    Centro de Enfermedades del Piso Pelviano CEPP, Clinica Las Condes, Santiago, Chile Electronic address
    Cir Esp 92:95-9. 2014
    ..KESS score before and after PPR were compared. Mann-Whitney-Wilcoxon rank sum test for paired samples was used for statistical analysis, p value <0,05 was considered as significant...
  12. ncbi request reprint Mutational screening of the APC gene in Chilean families with familial adenomatous polyposis: nine novel truncating mutations
    Marjorie K De la Fuente
    Departamento de Biologia Celular y Molecular, Facultad de Ciencias Biologicas, Pontificia Universidad Catolica de Chile, Santiago, Chile
    Dis Colon Rectum 50:2142-8. 2007
    ..This study was designed to identify germline mutation in the adenomatous polyposis coli gene in Chilean families with familial adenomatous polyposis...
  13. doi request reprint Increased production of soluble TLR2 by lamina propria mononuclear cells from ulcerative colitis patients
    Enzo Candia
    Disciplinary Program of Immunology, Institute of Biomedical Sciences, Faculty of Medicine, Universidad de Chile, Santiago, CL 8380453, Chile
    Immunobiology 217:634-42. 2012
    ..The increased production of sTLR2 suggests that a differential regulating factor of the innate immune system is present in the intestinal mucosa of UC patients...