Jorge A Carvajal

Summary

Country: Chile

Publications

  1. doi request reprint The role of brain natriuretic peptide in maintaining myometrial quiescence during pregnancy
    Jorge A Carvajal
    Marcoleta 391, Centro de Investigaciones Medicas, Pontificia Universidad Catolica de Chile, Santiago, Chile
    Exp Physiol 99:489-94. 2014
  2. pmc Mechanical stretch increases brain natriuretic peptide production and secretion in the human fetal membranes
    Jorge A Carvajal
    Unidad de Medicina Materno Fetal, División de Obstetricia y Ginecología, Pontificia Universidad Catolica de Chile, Santiago, Chile
    Reprod Sci 20:597-604. 2013
  3. doi request reprint Brain natriuretic peptide (BNP) produced by the human chorioamnion may mediate pregnancy myometrial quiescence
    Jorge A Carvajal
    Unidad de Medicina Materno Fetal, Departamento de Obstetricia y Ginecologia, Pontificia Universidad Catolica de Chile, Santiago, Chile
    Reprod Sci 16:32-42. 2009
  4. ncbi request reprint Mechanisms of paracrine regulation by fetal membranes of human uterine quiescence
    Jorge A Carvajal
    Departmento de Obstetricia y Ginecologia, Unidad de Medicina Materno Fetal, Facultad de Medicina, Pontificia Universidad Catolica de Chile, Santiago, Chile
    J Soc Gynecol Investig 13:343-9. 2006
  5. ncbi request reprint [Under diagnosis of fetal growth restriction by the new growth curves of the Chilean Ministry of Health]
    Jorge A Carvajal
    Departamento de Obstetricia y Ginecologia, Facultad de Medicina, Pontificia Universidad Catolica de Chile, Chile
    Rev Med Chil 135:436-42. 2007
  6. ncbi request reprint Intrahepatic cholestasis of pregnancy: an intriguing pregnancy-specific disorder
    Alfredo M Germain
    Laboratory of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, Pontificia Universidad Catolica de Chile, School of Medicine, Santiago, Chile
    J Soc Gynecol Investig 9:10-4. 2002
  7. doi request reprint Isoform alpha of PKC may contribute to the maintenance of pregnancy myometrial quiescence in humans
    Nicolás M Jofré
    Unidad de Medicina Materno Fetal, División de Obstetricia y Ginecología, Pontificia Universidad Catolica de Chile, Santiago, Chile
    Reprod Sci 20:69-77. 2013
  8. ncbi request reprint Bile acids increase response and expression of human myometrial oxytocin receptor
    Alfredo M Germain
    Department of Obstetrics and Gynecology, Pontificia Universidad Catolica de Chile School of Medicine, Santiago, Chile
    Am J Obstet Gynecol 189:577-82. 2003
  9. doi request reprint Maternal, perinatal and infant outcome of spontaneous pregnancy in the sixth decade of life
    Enrique Donoso
    Unidad de Medicina Materno Fetal, Departamento de Obstetricia y Ginecologia, Pontificia Universidad Catolica de Chile, Santiago, Chile
    Maturitas 59:381-6. 2008
  10. ncbi request reprint Chorion-induced myometrial relaxation is mediated by large-conductance Ca2+-activated K+ channel opening in the guinea pig
    Jorge A Carvajal
    Department of Obstetrics, Gynecology and Reproductive Sciences, University of Maryland Baltimore, School of Medicine, Baltimore, MD 21201, USA
    Am J Obstet Gynecol 188:84-91. 2003

Collaborators

Detail Information

Publications10

  1. doi request reprint The role of brain natriuretic peptide in maintaining myometrial quiescence during pregnancy
    Jorge A Carvajal
    Marcoleta 391, Centro de Investigaciones Medicas, Pontificia Universidad Catolica de Chile, Santiago, Chile
    Exp Physiol 99:489-94. 2014
    ..Furthermore, it is postulated that a premature decrease of BNP production by the fetal membranes may cause preterm labour and preterm birth. ..
  2. pmc Mechanical stretch increases brain natriuretic peptide production and secretion in the human fetal membranes
    Jorge A Carvajal
    Unidad de Medicina Materno Fetal, División de Obstetricia y Ginecología, Pontificia Universidad Catolica de Chile, Santiago, Chile
    Reprod Sci 20:597-604. 2013
    ..We postulate BNP is an important regulator of myometrial contractility during pregnancy, and its production is modulated by both stretch and progressive increase in EGF levels during pregnancy...
  3. doi request reprint Brain natriuretic peptide (BNP) produced by the human chorioamnion may mediate pregnancy myometrial quiescence
    Jorge A Carvajal
    Unidad de Medicina Materno Fetal, Departamento de Obstetricia y Ginecologia, Pontificia Universidad Catolica de Chile, Santiago, Chile
    Reprod Sci 16:32-42. 2009
    ..We conclude that locally produced BNP may be involved in generating myometrial quiescence during pregnancy. Further, a premature decrease of BNP production may cause preterm labor...
  4. ncbi request reprint Mechanisms of paracrine regulation by fetal membranes of human uterine quiescence
    Jorge A Carvajal
    Departmento de Obstetricia y Ginecologia, Unidad de Medicina Materno Fetal, Facultad de Medicina, Pontificia Universidad Catolica de Chile, Santiago, Chile
    J Soc Gynecol Investig 13:343-9. 2006
    ..To test the hypothesis that fetal membranes (chorion or amnion) release one or more factors responsible for myometrial quiescence...
  5. ncbi request reprint [Under diagnosis of fetal growth restriction by the new growth curves of the Chilean Ministry of Health]
    Jorge A Carvajal
    Departamento de Obstetricia y Ginecologia, Facultad de Medicina, Pontificia Universidad Catolica de Chile, Chile
    Rev Med Chil 135:436-42. 2007
    ..Nationwide implementation of new fetal growth charts, requires a lower fetal weight for the diagnosis of FGR, compared to previous ones. This may lead to an under diagnosis of FGR in a large proportion of neonates...
  6. ncbi request reprint Intrahepatic cholestasis of pregnancy: an intriguing pregnancy-specific disorder
    Alfredo M Germain
    Laboratory of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, Pontificia Universidad Catolica de Chile, School of Medicine, Santiago, Chile
    J Soc Gynecol Investig 9:10-4. 2002
    ..To review animal and human data available regarding the etiology, maternal and fetal impact, and treatment of intrahepatic cholestasis of pregnancy (ICP)...
  7. doi request reprint Isoform alpha of PKC may contribute to the maintenance of pregnancy myometrial quiescence in humans
    Nicolás M Jofré
    Unidad de Medicina Materno Fetal, División de Obstetricia y Ginecología, Pontificia Universidad Catolica de Chile, Santiago, Chile
    Reprod Sci 20:69-77. 2013
    ..Additionally, our data demonstrate an association between reduced PKCα activity and preterm labor, which merits further investigation...
  8. ncbi request reprint Bile acids increase response and expression of human myometrial oxytocin receptor
    Alfredo M Germain
    Department of Obstetrics and Gynecology, Pontificia Universidad Catolica de Chile School of Medicine, Santiago, Chile
    Am J Obstet Gynecol 189:577-82. 2003
    ..We tested the hypothesis that during intrahepatic cholestasis of pregnancy bile acids activate the myometrial oxytocin receptor pathway...
  9. doi request reprint Maternal, perinatal and infant outcome of spontaneous pregnancy in the sixth decade of life
    Enrique Donoso
    Unidad de Medicina Materno Fetal, Departamento de Obstetricia y Ginecologia, Pontificia Universidad Catolica de Chile, Santiago, Chile
    Maturitas 59:381-6. 2008
    ..Pregnancy in the older woman is a well-known risk factor for perinatal morbidity and mortality...
  10. ncbi request reprint Chorion-induced myometrial relaxation is mediated by large-conductance Ca2+-activated K+ channel opening in the guinea pig
    Jorge A Carvajal
    Department of Obstetrics, Gynecology and Reproductive Sciences, University of Maryland Baltimore, School of Medicine, Baltimore, MD 21201, USA
    Am J Obstet Gynecol 188:84-91. 2003
    ..We previously demonstrated that chorion releases a factor that inhibits both spontaneous and oxytocin-stimulated myometrial contractility. Here, we investigate the mechanism of action of this unidentified substance...