Research Topics
| Jorge A CarvajalSummaryCountry: Chile Publications
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Detail Information
Publications
Mechanisms of paracrine regulation by fetal membranes of human uterine quiescenceJorge A Carvajal
Departmento de Obstetricia y Ginecologia, Unidad de Medicina Materno Fetal, Facultad de Medicina, Pontificia Universidad Catolica de Chile, Santiago, Chile
J Soc Gynecol Investig 13:343-9. 2006..To test the hypothesis that fetal membranes (chorion or amnion) release one or more factors responsible for myometrial quiescence...
[Under diagnosis of fetal growth restriction by the new growth curves of the Chilean Ministry of Health]Jorge A Carvajal
Departamento de Obstetricia y Ginecologia, Facultad de Medicina, Pontificia Universidad Catolica de Chile, Chile
Rev Med Chil 135:436-42. 2007..Nationwide implementation of new fetal growth charts, requires a lower fetal weight for the diagnosis of FGR, compared to previous ones. This may lead to an under diagnosis of FGR in a large proportion of neonates...
Brain natriuretic peptide (BNP) produced by the human chorioamnion may mediate pregnancy myometrial quiescenceJorge A Carvajal
Unidad de Medicina Materno Fetal, Departamento de Obstetricia y Ginecologia, Pontificia Universidad Catolica de Chile, Santiago, Chile
Reprod Sci 16:32-42. 2009..We conclude that locally produced BNP may be involved in generating myometrial quiescence during pregnancy. Further, a premature decrease of BNP production may cause preterm labor...
Intrahepatic cholestasis of pregnancy: an intriguing pregnancy-specific disorderAlfredo M Germain
Laboratory of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, Pontificia Universidad Catolica de Chile, School of Medicine, Santiago, Chile
J Soc Gynecol Investig 9:10-4. 2002..To review animal and human data available regarding the etiology, maternal and fetal impact, and treatment of intrahepatic cholestasis of pregnancy (ICP)...
Isoform alpha of PKC may contribute to the maintenance of pregnancy myometrial quiescence in humansNicolás M Jofré
Unidad de Medicina Materno Fetal, División de Obstetricia y Ginecología, Pontificia Universidad Catolica de Chile, Santiago, Chile
Reprod Sci 20:69-77. 2013..Additionally, our data demonstrate an association between reduced PKCα activity and preterm labor, which merits further investigation...
Bile acids increase response and expression of human myometrial oxytocin receptorAlfredo M Germain
Department of Obstetrics and Gynecology, , Santiago, Chile
Am J Obstet Gynecol 189:577-82. 2003..CONCLUSION: We demonstrate that during intrahepatic cholestasis of pregnancy, an activation of the oxytocin receptor pathway occurs. This event seems to be the result of a cholic acid-mediated increase in oxytocin-receptor expression...
Maternal, perinatal and infant outcome of spontaneous pregnancy in the sixth decade of lifeEnrique Donoso
Unidad de Medicina Materno Fetal, Departamento de Obstetricia y Ginecologia, Pontificia Universidad Catolica de Chile, Santiago, Chile
Maturitas 59:381-6. 2008..Pregnancy in the older woman is a well-known risk factor for perinatal morbidity and mortality...
Chorion-induced myometrial relaxation is mediated by large-conductance Ca2+-activated K+ channel opening in the guinea pigJorge A Carvajal
Department of Obstetrics, Gynecology and Reproductive Sciences, University of Maryland Baltimore, School of Medicine, Baltimore, MD 21201, USA
Am J Obstet Gynecol 188:84-91. 2003..CONCLUSION: Chorion-induced relaxation of oxytocin-stimulated myometrial contraction is, in great part, the product of a paracrine substance that opens myometrial large conductance Ca(2+)-activated K(+) channels...
