- Gutierrez J, Cabrera D, Brandan E. Glypican-1 regulates myoblast response to HGF via Met in a lipid raft-dependent mechanism: effect on migration of skeletal muscle precursor cells. Skelet Muscle. 2014;4:5 pubmed publisher..In addition, glypican-1 was required for in vitro and in vivo HGF-dependent myoblast migration. Glypican-1 is a regulator of HGF-dependent signaling via Met in lipid raft domains. ..
- Morales M, AcuÃ±a M, Cabrera D, Goldschmeding R, Brandan E. The pro-fibrotic connective tissue growth factor (CTGF/CCN2) correlates with the number of necrotic-regenerative foci in dystrophic muscle. J Cell Commun Signal. 2018;12:413-421 pubmed publisher..Thus, CCN2 appears to be involved in the fibrotic response as well as in the inflammatory response in the dystrophic skeletal muscle. ..
- Acuña M, Salas D, Córdova Casanova A, Cruz Soca M, Cespedes C, Vio C, et al. Blockade of Bradykinin receptors worsens the dystrophic phenotype of mdx mice: differential effects for B1 and B2 receptors. J Cell Commun Signal. 2018;12:589-601 pubmed publisher..These results indicate that the endogenous KKS has a protective role in the dystrophic muscle. The KKS may be a new target for future therapies to reduce inflammation and fibrosis in dystrophic muscle. ..