Claudia Altamirano

Summary

Country: Chile

Publications

  1. ncbi request reprint Analysis of CHO cells metabolic redistribution in a glutamate-based defined medium in continuous culture
    C Altamirano
    Departament d Enginyeria Quimica, Escola Tecnica Superior d Enginyeria, Universitat Autonoma de Barcelona, 08193 Bellaterra, Barcelona, Spain
    Biotechnol Prog 17:1032-41. 2001
  2. ncbi request reprint Strategies for fed-batch cultivation of t-PA producing CHO cells: substitution of glucose and glutamine and rational design of culture medium
    C Altamirano
    Escuela de Ingeniería Bioquímica, Facultad de Ingenieria, Universidad Catolica de Valparaiso, Av Brasil 2147, Valparaiso, Chile
    J Biotechnol 110:171-9. 2004
  3. ncbi request reprint Considerations on the lactate consumption by CHO cells in the presence of galactose
    Claudia Altamirano
    Escuela de Ingeniería Bioquímica, Pontificia Universidad Catolica de Valparaiso, Chile
    J Biotechnol 125:547-56. 2006
  4. doi request reprint Relationship between tissue plasminogen activator production and specific growth rate in Chinese hamster ovary cells cultured in mannose at low temperature
    Julio Berrios
    Escuela de Ingeniería Bioquímica, Pontificia Universidad Catolica de Valparaiso, Av Brasil 2147, Casilla, 4059, Valparaiso, Chile
    Biotechnol Lett 31:1493-7. 2009
  5. ncbi request reprint Decoupling cell growth and product formation in Chinese hamster ovary cells through metabolic control
    C Altamirano
    , , , 08193 Bellaterra, Barcelona, Spain
    Biotechnol Bioeng 76:351-60. 2001
  6. ncbi request reprint Differential Effect of Culture Temperature and Specific Growth Rate on CHO Cell Behavior in Chemostat Culture
    Mauricio Vergara
    School of Biochemical Engineering, Pontificia Universidad Católica de Valparaiíso, Valparaiso, Chile
    PLoS ONE 9:e93865. 2014
  7. doi request reprint Alginate production and alg8 gene expression by Azotobacter vinelandii in continuous cultures
    Alvaro Díaz-Barrera
    Escuela de Ingeniería Bioquímica, Pontificia Universidad Catόlica de Valparaíso, Av Brasil 2147, Casilla 4059, Valparaiso, Chile
    J Ind Microbiol Biotechnol 39:613-21. 2012
  8. pmc A novel liquid medium for the efficient growth of the salmonid pathogen Piscirickettsia salmonis and optimization of culture conditions
    Mirtha Henríquez
    Escuela de Ingeniería Bioquímica, Pontificia Universidad Catolica de Valparaiso, Valparaiso, Chile
    PLoS ONE 8:e71830. 2013
  9. ncbi request reprint Production of alginate by Azotobacter vinelandii grown at two bioreactor scales under oxygen-limited conditions
    Alvaro Díaz-Barrera
    Escuela de Ingeniería Bioquímica, Pontificia Universidad Catolica de Valparaiso, Av Brasil 2147, 4059, Casilla, Valparaiso, Chile
    Bioprocess Biosyst Eng 37:1133-40. 2014

Collaborators

  • Alvaro Díaz-Barrera
  • Ramon Gonzalez
  • Andres Illanes
  • Julio Berrios
  • Mauricio Vergara
  • Mirtha Henríquez
  • Juan Reyes
  • Nelson Osses
  • Silvana Becerra
  • María Rodríguez-Moyá
  • Vitalia Henriquez
  • Ernesto Gonzalez
  • Fernando A Gómez
  • IRENE MARTINEZ
  • Sergio H Marshall
  • Consuelo Bazán

Detail Information

Publications9

  1. ncbi request reprint Analysis of CHO cells metabolic redistribution in a glutamate-based defined medium in continuous culture
    C Altamirano
    Departament d Enginyeria Quimica, Escola Tecnica Superior d Enginyeria, Universitat Autonoma de Barcelona, 08193 Bellaterra, Barcelona, Spain
    Biotechnol Prog 17:1032-41. 2001
    ..It is, therefore, the combination of growth rate and carbon and energy source availability that determines the level of t-PA production in continuous culture...
  2. ncbi request reprint Strategies for fed-batch cultivation of t-PA producing CHO cells: substitution of glucose and glutamine and rational design of culture medium
    C Altamirano
    Escuela de Ingeniería Bioquímica, Facultad de Ingenieria, Universidad Catolica de Valparaiso, Av Brasil 2147, Valparaiso, Chile
    J Biotechnol 110:171-9. 2004
    ..This allowed an increase in cell growth and cell viability with respect to a fed-batch culture in which only glucose was used in the fed stage...
  3. ncbi request reprint Considerations on the lactate consumption by CHO cells in the presence of galactose
    Claudia Altamirano
    Escuela de Ingeniería Bioquímica, Pontificia Universidad Catolica de Valparaiso, Chile
    J Biotechnol 125:547-56. 2006
    ..This metabolic behavior is further investigated by using metabolic flux analysis, suggesting that the lactate produced is not used in the oxidative metabolism through the TCA cycle. Metabolic fate of the lactate consumed is discussed...
  4. doi request reprint Relationship between tissue plasminogen activator production and specific growth rate in Chinese hamster ovary cells cultured in mannose at low temperature
    Julio Berrios
    Escuela de Ingeniería Bioquímica, Pontificia Universidad Catolica de Valparaiso, Av Brasil 2147, Casilla, 4059, Valparaiso, Chile
    Biotechnol Lett 31:1493-7. 2009
    ....
  5. ncbi request reprint Decoupling cell growth and product formation in Chinese hamster ovary cells through metabolic control
    C Altamirano
    , , , 08193 Bellaterra, Barcelona, Spain
    Biotechnol Bioeng 76:351-60. 2001
    ..The use of this metabolic shift enables the generation of biphasic processes, with a first phase with cell growth on glucose and a second stationary phase on galactose, which is particularly suited to perfusion systems...
  6. ncbi request reprint Differential Effect of Culture Temperature and Specific Growth Rate on CHO Cell Behavior in Chemostat Culture
    Mauricio Vergara
    School of Biochemical Engineering, Pontificia Universidad Católica de Valparaiíso, Valparaiso, Chile
    PLoS ONE 9:e93865. 2014
    ..Interestingly, reduction of metabolism could not be associated with a decrease in culture temperature, but rather with a decrease in specific growth rate. ..
  7. doi request reprint Alginate production and alg8 gene expression by Azotobacter vinelandii in continuous cultures
    Alvaro Díaz-Barrera
    Escuela de Ingeniería Bioquímica, Pontificia Universidad Catόlica de Valparaíso, Av Brasil 2147, Casilla 4059, Valparaiso, Chile
    J Ind Microbiol Biotechnol 39:613-21. 2012
    ....
  8. pmc A novel liquid medium for the efficient growth of the salmonid pathogen Piscirickettsia salmonis and optimization of culture conditions
    Mirtha Henríquez
    Escuela de Ingeniería Bioquímica, Pontificia Universidad Catolica de Valparaiso, Valparaiso, Chile
    PLoS ONE 8:e71830. 2013
    ..Therefore, these results represent a breakthrough regarding P. salmonis research in order to optimize pure P. salmonis growth in liquid blood and serum free medium. ..
  9. ncbi request reprint Production of alginate by Azotobacter vinelandii grown at two bioreactor scales under oxygen-limited conditions
    Alvaro Díaz-Barrera
    Escuela de Ingeniería Bioquímica, Pontificia Universidad Catolica de Valparaiso, Av Brasil 2147, 4059, Casilla, Valparaiso, Chile
    Bioprocess Biosyst Eng 37:1133-40. 2014
    ..These findings open the possibility of using [Formula: see text] instead of OTRmax as a scaling criterion to produce polymers with similar molecular weights during fermentation...