Intensity modulated radiotherapy for sinonasal malignancies with a focus on optic pathway preservationAlexander Chi
Department of Radiation Oncology, West Virginia University, 1 Medical Center Dr, Morgantown, Morgantown, WV 26506, USA
J Hematol Oncol 6:4. 2013
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- Dosimetric selection for helical tomotherapy based stereotactic ablative radiotherapy for early-stage non-small cell lung cancer or lung metastases
Alexander Chi
Department of Radiation Oncology, West Virginia University, Morgantown, West Virginia, United States of America
PLoS ONE 7:e35809. 2012
..In this study, we investigate the dosimetric selection criteria for HT based SABR delivering 70 Gy in 10 fractions to avoid severe toxicity in the treatment of centrally located lesions when adequate target dose coverage is desired...
Correlation of three different approaches of small bowel delineation and acute lower gastrointestinal toxicity in adjuvant pelvic intensity-modulated radiation therapy for endometrial cancerAlexander Chi
Department of Radiation Oncology, West Virginia University, 1 Medical Center Dr, Morgantown, WV 26506, USA
Technol Cancer Res Treat 11:353-9. 2012
..0347). Thus, the proportion of small bowel contoured as IC in the high dose region can potentially be an important predictor for acute lower GI toxicity during and after postoperative pelvic IMRT...
Intensity-modulated radiotherapy after extrapleural pneumonectomy in the combined-modality treatment of malignant pleural mesotheliomaAlexander Chi
Department of Radiation Oncology, The University of Arizona, Tucson, Arizona 85724, USA
J Thorac Oncol 6:1132-41. 2011
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- Feasibility of helical tomotherapy in stereotactic body radiation therapy for centrally located early stage non‒small-cell lung cancer or lung metastases
Alexander Chi
Department of Radiation Oncology, The University of Arizona, Tucson, AZ 85724 5081, USA
Int J Radiat Oncol Biol Phys 81:856-62. 2011
..To investigate the ability of helical tomotherapy (HT) to spare critical organs immediately adjacent to the tumor target in stereotactic body radiation therapy (SBRT) for centrally located lung lesions...
- Stereotactic body radiation therapy in non-small-cell lung cancer: linking radiobiological modeling and clinical outcome
Alexander Chi
Department of Radiation Oncology, University of Arizona, Tucson, 85724, USA
Am J Clin Oncol 34:432-41. 2011
..Furthermore, the validity of the linear quadratic formalism in the high dose range of SBRT for lung cancer is explored...
- Systemic review of the patterns of failure following stereotactic body radiation therapy in early-stage non-small-cell lung cancer: clinical implications
Alexander Chi
Department of Radiation Oncology, University of Arizona, 1501 N Campbell Ave, Tucson, AZ 85724, USA
Radiother Oncol 94:1-11. 2010
..To analyze the patterns of failure, the toxicity profile, and the factors influencing efficacy of stereotactic body radiation (SBRT) for early-stage non-small-cell lung cancer (NSCLC)...
- Feasibility of tomotherapy-based image-guided radiotherapy for locally advanced oropharyngeal cancer
Nam P Nguyen
Department of Radiation Oncology, University of Arizona, Tucson, Arizona, United States of America
PLoS ONE 8:e60268. 2013
..A retrospective review of 33 patients undergoing concurrent chemoradiation for locally advanced oropharyngeal cancers was conducted. Radiotherapy planning, treatment toxicity and loco-regional control were assessed...
- Feasibility of image-guided radiotherapy based on helical tomotherapy to reduce contralateral parotid dose in head and neck cancer
Nam P Nguyen
Department of Radiation Oncology, University of Arizona, Tucson, AZ 85724, USA
BMC Cancer 12:175. 2012
..To evaluate the feasibility of image-guided radiotherapy based on helical Tomotherapy to spare the contralateral parotid gland in head and neck cancer patients with unilateral or no neck node metastases...
- Effectiveness of intensity-modulated and image-guided radiotherapy to spare the mandible from excessive radiation
Nam P Nguyen
Department of Radiation Oncology, University of Arizona, Tucson, AZ, United States
Oral Oncol 48:653-7. 2012
..Sharp dose falloff associated with IMRT and IGRT decreased excessive radiation of the mandible and may reduce the risks of osteoradionecrosis...
- Feasibility of intensity-modulated and image-guided radiotherapy for functional organ preservation in locally advanced laryngeal cancer
Nam P Nguyen
Department of Radiation Oncology, University of Arizona, Tucson, Arizona, USA
PLoS ONE 7:e42729. 2012
..Loco-regional control, speech quality and feeding-tube dependency were assessed during follow-up visits...
- Effectiveness of prophylactic retropharyngeal lymph node irradiation in patients with locally advanced head and neck cancer
Nam P Nguyen
Department of Radiation Oncology, University of Arizona, Tucson, USA
BMC Cancer 12:253. 2012
..The aim of the study is to assess the effectiveness of intensity-modulated radiotherapy (IMRT) or image-guided radiotherapy (IGRT) for the prevention of retropharyngeal nodal recurrences in locally advanced head and neck cancer...
- Feasibility of image-guided radiotherapy based on tomotherapy for the treatment of locally advanced anal carcinoma
Nam P Nguyen
Department of Radiation Oncology, University of Arizona, 1501 N Campbell Ave, Tucson, AZ 85724 5081, USA
Anticancer Res 31:4393-6. 2011
..The feasibility of new radiotherapy techniques such as image-guided radiotherapy (IGRT) in combination with chemotherapy for the treatment of this malignancy was assessed...
- Impact of image-guided radiotherapy to reduce laryngeal edema following treatment for non-laryngeal and non-hypopharyngeal head and neck cancers
Nam P Nguyen
Department of Radiation Oncology, University of Arizona, Tucson, AZ 85724 5081, United States
Oral Oncol 47:900-4. 2011
..IGRT results in low rates and low severity of laryngeal edema following treatment for non-laryngeal and non-hypopharyngeal head and neck cancers and may preserve voice quality...
- Critical Structure Sparing in Stereotactic Ablative Radiotherapy for Central Lung Lesions: Helical Tomotherapy vs. Volumetric Modulated Arc Therapy
Alexander Chi
Department of Radiation Oncology, West Virginia University, Morgantown, West Virginia, United States of America
PLoS ONE 8:e59729. 2013
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- Effectiveness of image-guided radiotherapy for locally advanced rectal cancer
Nam P Nguyen
Department of Radiation Oncology, University of Arizona, Tucson, AZ, USA
Ann Surg Oncol 18:380-5. 2011
..We have assessed the effectiveness of IGRT for locally advanced rectal cancer...
- Single versus customized treatment planning for image-guided high-dose-rate brachytherapy for cervical cancer: dosimetric comparison and predicting factor for organs at risk overdose with single plan approach
Alexander Chi
Department of Radiation Oncology, Loyola University Medical Center, Maywood, IL 60153, USA
Int J Radiat Oncol Biol Phys 75:309-14. 2009
..To compare the dose distribution between customized planning (CP) and adopting a single plan (SP) in multifractionated high-dose-rate brachytherapy and to establish predictors for the necessity of CP in a given patient...
