L Cheng

Summary

Publications

  1. ncbi request reprint Urothelial papilloma of the bladder. Clinical and biologic implications
    L Cheng
    Department of Pathology, Indiana University School of Medicine, Indianapolis, Indiana, USA
    Cancer 86:2098-101. 1999
  2. ncbi request reprint Neurofibroma of the urinary bladder
    L Cheng
    Department of Pathology and Urology, Indiana University School of Medicine, Indianapolis, USA
    Cancer 86:505-13. 1999
  3. ncbi request reprint Papillary urothelial neoplasms of low malignant potential. Clinical and biologic implications
    L Cheng
    Department of Pathology and Urology, Indiana University School of Medicine, Indianapolis, Indiana, USA
    Cancer 86:2102-8. 1999
  4. ncbi request reprint Extranodal extension in lymph node-positive prostate cancer
    L Cheng
    Department of Pathology, Indiana University School of Medicine, Indianapolis 46202, USA
    Mod Pathol 13:113-8. 2000
  5. ncbi request reprint Tumor size predicts the survival of patients with pathologic stage T2 bladder carcinoma: a critical evaluation of the depth of muscle invasion
    L Cheng
    Department of Pathology, Indiana University School of Medicine, Indianapolis 46202, USA
    Cancer 85:2638-47. 1999
  6. ncbi request reprint Predictors of cancer progression in T1a prostate adenocarcinoma
    L Cheng
    Department of Pathology, Indiana University School of Medicine, Indianapolis 46202, USA
    Cancer 85:1300-4. 1999
  7. ncbi request reprint Cell proliferation in prostate cancer patients with lymph node metastasis: a marker for progression
    L Cheng
    Department of Pathology, Indiana University School of Medicine, Indianapolis 46202, USA
    Clin Cancer Res 5:2820-3. 1999
  8. ncbi request reprint The cell cycle inhibitors p21WAF1 and p27KIP1 are associated with survival in patients treated by salvage prostatectomy after radiation therapy
    L Cheng
    Department of Pathology, Indiana University School of Medicine, Indianapolis 46202, USA
    Clin Cancer Res 6:1896-9. 2000
  9. ncbi request reprint Diagnosis and grading of bladder cancer and associated lesions
    D G Bostwick
    Department of Pathology, Mayo Clinic, Rochester, Minnesota, USA
    Urol Clin North Am 26:493-507. 1999
  10. ncbi request reprint Diagnosis of prostate cancer in needle biopsies after radiation therapy
    L Cheng
    Department of Pathology, Indiana University School of Medicine, Indianapolis 46202, USA
    Am J Surg Pathol 23:1173-83. 1999

Detail Information

Publications28

  1. ncbi request reprint Urothelial papilloma of the bladder. Clinical and biologic implications
    L Cheng
    Department of Pathology, Indiana University School of Medicine, Indianapolis, Indiana, USA
    Cancer 86:2098-101. 1999
    ..An international consensus has been reached regarding diagnostic criteria for papilloma of the urinary bladder. However, the incidences of recurrence and progression in patients with urothelial papilloma are uncertain...
  2. ncbi request reprint Neurofibroma of the urinary bladder
    L Cheng
    Department of Pathology and Urology, Indiana University School of Medicine, Indianapolis, USA
    Cancer 86:505-13. 1999
    ..Neurofibroma of the urinary bladder is rare. Only isolated case reports have appeared. Information regarding the long term follow-up of patients with neurofibroma is limited...
  3. ncbi request reprint Papillary urothelial neoplasms of low malignant potential. Clinical and biologic implications
    L Cheng
    Department of Pathology and Urology, Indiana University School of Medicine, Indianapolis, Indiana, USA
    Cancer 86:2102-8. 1999
    ..Knowledge of the long term outcomes of patients with papillary urothelial neoplasms of low malignant potential (LMP) is limited...
  4. ncbi request reprint Extranodal extension in lymph node-positive prostate cancer
    L Cheng
    Department of Pathology, Indiana University School of Medicine, Indianapolis 46202, USA
    Mod Pathol 13:113-8. 2000
    ..In contrast, nodal cancer volume was predictive of distant metastasis-free survival and cancer-specific survival...
  5. ncbi request reprint Tumor size predicts the survival of patients with pathologic stage T2 bladder carcinoma: a critical evaluation of the depth of muscle invasion
    L Cheng
    Department of Pathology, Indiana University School of Medicine, Indianapolis 46202, USA
    Cancer 85:2638-47. 1999
    ..Evidence has accumulated that cancers invading the superficial muscle wall (T2a) behave similarly to those invading the deep muscle wall (T2b). Quantitative analysis of the depth of invasion in relation to patient outcome is needed...
  6. ncbi request reprint Predictors of cancer progression in T1a prostate adenocarcinoma
    L Cheng
    Department of Pathology, Indiana University School of Medicine, Indianapolis 46202, USA
    Cancer 85:1300-4. 1999
    ..In the current study the authors attempted to identify such predictors of cancer progression in a large series of untreated patients with lengthy follow-up...
  7. ncbi request reprint Cell proliferation in prostate cancer patients with lymph node metastasis: a marker for progression
    L Cheng
    Department of Pathology, Indiana University School of Medicine, Indianapolis 46202, USA
    Clin Cancer Res 5:2820-3. 1999
    ..52 and 0.17, respectively). Our data indicate that assessment of cell proliferation in nodal metastasis is predictive of clinical outcome in prostate cancer patients with regional lymph node metastasis...
  8. ncbi request reprint The cell cycle inhibitors p21WAF1 and p27KIP1 are associated with survival in patients treated by salvage prostatectomy after radiation therapy
    L Cheng
    Department of Pathology, Indiana University School of Medicine, Indianapolis 46202, USA
    Clin Cancer Res 6:1896-9. 2000
    ..06 and 0.01, respectively). These findings indicate that p21 and p27 expression levels are significant predictors of survival for patients selected for salvage prostatectomy for recurrent prostate cancer...
  9. ncbi request reprint Diagnosis and grading of bladder cancer and associated lesions
    D G Bostwick
    Department of Pathology, Mayo Clinic, Rochester, Minnesota, USA
    Urol Clin North Am 26:493-507. 1999
    ..Uniformity of pathologic reporting should improve the comparability of different studies and therapies and provide more accurate information to urologists in managing patients...
  10. ncbi request reprint Diagnosis of prostate cancer in needle biopsies after radiation therapy
    L Cheng
    Department of Pathology, Indiana University School of Medicine, Indianapolis 46202, USA
    Am J Surg Pathol 23:1173-83. 1999
    ..Conversely, Gleason grade in postirradiation needle biopsy specimens appeared to provide useful predictive information and should be reported...
  11. ncbi request reprint Predicting the survival of bladder carcinoma patients treated with radical cystectomy
    L Cheng
    Department of Pathology, Indiana University School of Medicine, Indianapolis 46202, USA
    Cancer 88:2326-32. 2000
    ..Clinical outcomes vary for patients treated with radical cystectomy. The authors sought to identify factors associated with the survival of patients treated with radical cystectomy for urothelial carcinoma of the urinary bladder...
  12. ncbi request reprint Allelic imbalance in the clonal evolution of prostate carcinoma
    L Cheng
    Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis 46202, USA
    Cancer 85:2017-22. 1999
    ..To understand better the genetic basis of the clonal evolution of prostate carcinoma, the authors analyzed the pattern of allelic loss in 25 matched primary and metastatic prostate tumors...
  13. ncbi request reprint Dedifferentiation in the metastatic progression of prostate carcinoma
    L Cheng
    Department of Pathology and Urology, Indiana University School of Medicine, Indianapolis, Indiana, USA
    Cancer 86:657-63. 1999
    ..Detailed histologic analysis of primary prostate carcinoma and synchronous lymph node metastases may improve our understanding of the complex process of cancer progression and metastasis...
  14. ncbi request reprint Paraganglioma of the urinary bladder: can biologic potential be predicted?
    L Cheng
    Department of Pathology, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
    Cancer 88:844-52. 2000
    ..Paraganglioma of the urinary bladder is rarely encountered and its biologic behavior is uncertain. The authors sought to determine the prognostic factors that would predict patient outcome...
  15. ncbi request reprint Hemangioma of the urinary bladder
    L Cheng
    Department of Pathology and Urology, Indiana University School of Medicine, Indianapolis 46202, USA
    Cancer 86:498-504. 1999
    ..Hemangioma of the urinary bladder is rare and the long term outcome of patients is unknown...
  16. ncbi request reprint Predicting cancer progression in patients with stage T1 bladder carcinoma
    L Cheng
    Department of Pathology, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    J Clin Oncol 17:3182-7. 1999
    ..We sought to identify factors associated with cancer progression in a series of patients with stage T1 bladder carcinoma treated with a contemporary therapeutic approach...
  17. ncbi request reprint Substaging of T1 bladder carcinoma based on the depth of invasion as measured by micrometer: A new proposal
    L Cheng
    Department of Pathology and Urology, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
    Cancer 86:1035-43. 1999
    ..A significant number of T1 bladder carcinoma patients are understaged by transurethral resection of the bladder (TURB), indicating a substantial need for more accurate staging...
  18. ncbi request reprint Atypical nephrogenic metaplasia of the urinary tract: a precursor lesion?
    L Cheng
    Department of Pathology, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
    Cancer 88:853-61. 2000
    ..Nephrogenic metaplasia with cytologic atypia (atypical nephrogenic metaplasia) is occasionally encountered and its biologic potential is uncertain...
  19. ncbi request reprint Squamous papilloma of the urinary tract is unrelated to condyloma acuminata
    L Cheng
    Department of Pathology, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
    Cancer 88:1679-86. 2000
    ..To the authors' knowledge, there is no previous report of squamous papilloma of the urinary tract. It is uncertain whether there is a correlation between squamous papilloma, condyloma acuminatum, and verrucous carcinoma...
  20. ncbi request reprint Natural history of urothelial dysplasia of the bladder
    L Cheng
    Department of Pathology, Indiana University School of Medicine, Indianapolis 46202, USA
    Am J Surg Pathol 23:443-7. 1999
    ..The authors conclude that urothelial dysplasia is a significant risk for the development of CIS and invasive urothelial carcinoma, and patients with urothelial dysplasia should be followed up closely...
  21. ncbi request reprint Cancer heterogeneity and its biologic implications in the grading of urothelial carcinoma
    L Cheng
    Department of Pathology, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
    Cancer 88:1663-70. 2000
    ..Urothelial carcinoma of the bladder often contains areas with different histologic grades. The influence of cancer heterogeneity on grading and its relation to patient outcome is uncertain...
  22. ncbi request reprint Preoperative prediction of surgical margin status in patients with prostate cancer treated by radical prostatectomy
    L Cheng
    Department of Pathology and Urology, Indiana University School of Medicine, Indianapolis, IN, USA
    J Clin Oncol 18:2862-8. 2000
    ..We sought to determine the preoperative factors associated with surgical margin status in patients who underwent radical prostatectomy for prostate cancer...
  23. ncbi request reprint Risk of prostate carcinoma death in patients with lymph node metastasis
    L Cheng
    Department of Pathology, Indiana University School of Medicine, Indianapolis, Indiana, USA
    Cancer 91:66-73. 2001
    ..Results of published reports on survival among patients with lymph node metastasis are difficult to assess because of treatment selections. The extent to which lymph node status will have an impact on a patient's survival is uncertain...
  24. ncbi request reprint Treatment changes in prostatic hyperplasia and cancer, including androgen deprivation therapy and radiotherapy
    D G Bostwick
    Department of Pathology, Mayo Clinic, Rochester, Minnesota, USA
    Urol Clin North Am 26:465-79. 1999
    ..Pathologists must be aware of these distinct changes because of the reliance placed on nuclear and nucleolar size in the identification of prostate cancer, particularly in small specimens and lymph node metastases...
  25. ncbi request reprint Steam heat with an EDTA buffer and protease digestion optimizes immunohistochemical expression of basal cell-specific antikeratin 34betaE12 to discriminate cancer in prostatic epithelium
    K A Iczkowski
    Department of Pathology, Mayo Clinic Rochester, Minnesota 55905, USA
    Mod Pathol 12:1-4. 1999
    ..This helps to prevent misinterpretation of histologic mimics of cancer, such as atrophic acini and high-grade prostatic intraepithelial neoplasia, that result from false-negative staining...
  26. doi request reprint Outcome analysis of patients with transformed teratoma to primitive neuroectodermal tumor
    Y Ehrlich
    Department of Urology, Melvin and Bren Simon Cancer Center, Indianapolis, IN, USA
    Ann Oncol 21:1846-50. 2010
    ..The emergence of a primitive neuroectodermal tumor (PNET) within a germ-cell tumor (GCT) is rare. We assess the prognosis and response to treatment...
  27. ncbi request reprint Cyclooxygenase-2 expression in human pancreatic adenocarcinomas
    M T Yip-Schneider
    Department of Medicine, Department of Biochemistry and Walther Oncology Center, Indiana University School of Medicine, Indianapolis 46202, USA
    Carcinogenesis 21:139-46. 2000
    ..Taken together, our data suggest that COX-2 may play an important role in pancreatic tumorigenesis and therefore be a promising chemotherapeutic target for the treatment of pancreatic cancer...
  28. ncbi request reprint Conserved genetic findings in metastatic bladder cancer: a possible utility of allelic loss of chromosomes 9p21 and 17p13 in diagnosis
    L Cheng
    Department of Pathology, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Arch Pathol Lab Med 125:1197-9. 2001
    ..Molecular analysis of microsatellite alterations of biologically distinct tumor cell subpopulations from the same patient may aid in the determination of tumor origin and further our understanding of the genetic basis of cancer progression...