Li Chen

Summary

Publications

  1. ncbi request reprint Interleukin-6 family of cytokines mediates isoproterenol-induced delayed STAT3 activation in mouse heart
    Feng Yin
    Institute of Vascular Medicine, Peking University Third Hospital and The Reference Laboratory of Education Ministry on Molecular Cardiology, Beijing 100083, People s Republic of China
    J Biol Chem 278:21070-5. 2003
  2. pmc A single nucleotide polymorphism in the matrix metalloproteinase 9 gene (-8202A/G) is associated with thoracic aortic aneurysms and thoracic aortic dissection
    Li Chen
    Cardiovascular Surgery Service, the Texas Heart Institute at St Luke s Episcopal Hospital, and the Division of Cardiothoracic Surgery, Baylor College of Medicine, Houston, Tex, USA
    J Thorac Cardiovasc Surg 131:1045-52. 2006
  3. ncbi request reprint Linkage disequilibrium and haplotype analysis of two single nucleotide polymorphisms in STK15 in Chinese
    Li Chen
    The Research Center for Medical Genomics and MOH Key Laboratory of Cell Biology, China Medical University, Shenyang 110001, China
    Yi Chuan Xue Bao 32:331-6. 2005
  4. ncbi request reprint Antiarrhythmic effect of atorvastatin on autoimmune myocarditis is mediated by improving myocardial repolarization
    Qizhu Tang
    Department of Cardiology, Renmin Hospital of Wuhan University, 238 Jiefang Rd, Wuhan 430060, P R China
    Life Sci 80:601-8. 2007
  5. ncbi request reprint Peritoneal fluid and serum concentration of interleukin-16 in women with endometriosis
    Xinmei Zhang
    Department of Gynecology, Women s Hospital, Zhejiang University School of Medicine, Hangzhou, China
    Acta Obstet Gynecol Scand 84:297-8. 2005
  6. ncbi request reprint Disparities in health information quality across the rural-urban continuum: where is coded data more reliable?
    Daniel Lorence
    Penn State Center for Technology Assessment, P O Box 1154, State College, PA 16801, USA
    J Med Syst 32:1-8. 2008
  7. ncbi request reprint [Relationship between 5,10-methylenetetrahydrofolate reductase genetic polymorphism and arsenic metabolism]
    Fu rong Deng
    Department of Occupational and Enviromental Health Sciences, Peking University School of Public Health, Beijing 100083, China
    Beijing Da Xue Xue Bao 39:149-52. 2007
  8. ncbi request reprint [Determination of interleukine-16 levels in peritoneal fluid and serum of women with endometriosis]
    Jun Lin
    The Obstetrics and Gynecology Hospital, College of Medicine, Zhejiang University, Hangzhou 310006, China
    Zhejiang Da Xue Xue Bao Yi Xue Ban 34:260-2. 2005
  9. ncbi request reprint [Study on the relationship between methylene tetrahydrofolate reductase gene (677C-->T) mutation and skin lesions in endemic arsenic poisoning]
    Li Chen
    School of Public Health, Peking University, Beijing 100083, China
    Wei Sheng Yan Jiu 34:146-8. 2005
  10. ncbi request reprint Effect of relaxin on myocardial ischemia injury induced by isoproterenol
    Jing Zhang
    Institute of Cardiovascular Research, Peking University First Hospital, Beijing 100034, China
    Peptides 26:1632-9. 2005

Collaborators

Detail Information

Publications62

  1. ncbi request reprint Interleukin-6 family of cytokines mediates isoproterenol-induced delayed STAT3 activation in mouse heart
    Feng Yin
    Institute of Vascular Medicine, Peking University Third Hospital and The Reference Laboratory of Education Ministry on Molecular Cardiology, Beijing 100083, People s Republic of China
    J Biol Chem 278:21070-5. 2003
    ....
  2. pmc A single nucleotide polymorphism in the matrix metalloproteinase 9 gene (-8202A/G) is associated with thoracic aortic aneurysms and thoracic aortic dissection
    Li Chen
    Cardiovascular Surgery Service, the Texas Heart Institute at St Luke s Episcopal Hospital, and the Division of Cardiothoracic Surgery, Baylor College of Medicine, Houston, Tex, USA
    J Thorac Cardiovasc Surg 131:1045-52. 2006
    ..The purpose of this study was to determine whether 3 single nucleotide polymorphisms in the matrix metalloproteinase 9 gene are associated with thoracic aortic aneurysms and dissection...
  3. ncbi request reprint Linkage disequilibrium and haplotype analysis of two single nucleotide polymorphisms in STK15 in Chinese
    Li Chen
    The Research Center for Medical Genomics and MOH Key Laboratory of Cell Biology, China Medical University, Shenyang 110001, China
    Yi Chuan Xue Bao 32:331-6. 2005
    ..11%), 91T-169G/91T-169A (4.15%), 91T-169A/91T-169A (1.55%). Whereas no 91A-169A haplotype was detected in all individuals examined in the current study, linkage disequilibrium (LD) between the two SNPs was found...
  4. ncbi request reprint Antiarrhythmic effect of atorvastatin on autoimmune myocarditis is mediated by improving myocardial repolarization
    Qizhu Tang
    Department of Cardiology, Renmin Hospital of Wuhan University, 238 Jiefang Rd, Wuhan 430060, P R China
    Life Sci 80:601-8. 2007
    ..Atorvastatin exerted the antiarrhythmic effects by selectively affecting cardiomyocyte ion channel activity and therefore improves myocardial repolarization...
  5. ncbi request reprint Peritoneal fluid and serum concentration of interleukin-16 in women with endometriosis
    Xinmei Zhang
    Department of Gynecology, Women s Hospital, Zhejiang University School of Medicine, Hangzhou, China
    Acta Obstet Gynecol Scand 84:297-8. 2005
  6. ncbi request reprint Disparities in health information quality across the rural-urban continuum: where is coded data more reliable?
    Daniel Lorence
    Penn State Center for Technology Assessment, P O Box 1154, State College, PA 16801, USA
    J Med Syst 32:1-8. 2008
    ..Related impacts on comparative cost and clinical performance assessment are discussed...
  7. ncbi request reprint [Relationship between 5,10-methylenetetrahydrofolate reductase genetic polymorphism and arsenic metabolism]
    Fu rong Deng
    Department of Occupational and Enviromental Health Sciences, Peking University School of Public Health, Beijing 100083, China
    Beijing Da Xue Xue Bao 39:149-52. 2007
    ..To study the relationship between 5,10-methylenetetrahydrofolate reductase(MTHFR) genetic polymorphism and arsenic metabolism and the role of folate in it...
  8. ncbi request reprint [Determination of interleukine-16 levels in peritoneal fluid and serum of women with endometriosis]
    Jun Lin
    The Obstetrics and Gynecology Hospital, College of Medicine, Zhejiang University, Hangzhou 310006, China
    Zhejiang Da Xue Xue Bao Yi Xue Ban 34:260-2. 2005
    ..To investigate the role of interleukine-16 (IL-16) in the pathogenesis of endometriosis...
  9. ncbi request reprint [Study on the relationship between methylene tetrahydrofolate reductase gene (677C-->T) mutation and skin lesions in endemic arsenic poisoning]
    Li Chen
    School of Public Health, Peking University, Beijing 100083, China
    Wei Sheng Yan Jiu 34:146-8. 2005
    ..Methylene tetrahydrofolate reductase (MTHFR) is the key enzyme in folate metabolism. We examined whether single nucleotide 677 C-->T mutation in the MTHFR gene could affect the occurrence of skin lesions in endemic arsenic poisoning...
  10. ncbi request reprint Effect of relaxin on myocardial ischemia injury induced by isoproterenol
    Jing Zhang
    Institute of Cardiovascular Research, Peking University First Hospital, Beijing 100034, China
    Peptides 26:1632-9. 2005
    ....
  11. ncbi request reprint [Association of a polymorphism in MDR1 C3435T with response to antiepileptic drug treatment in ethic Han Chinese children with epilepsy]
    Li Chen
    Department of Neurology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China
    Zhongguo Dang Dai Er Ke Za Zhi 9:11-4. 2007
    ..This study attempted to replicate this finding by examining the association of this genetic polymorphism with response to antiepileptic drug treatment in ethnic Han Chinese children with epilepsy...
  12. ncbi request reprint Interleukin-10 promoter polymorphisms in patients with hepatitis B virus infection or hepatocellular carcinoma in Chinese Han ethnic population
    Juan Wang
    College of Life Sciences, Nankai University, Tianjin 300071, China
    Hepatobiliary Pancreat Dis Int 5:60-4. 2006
    ..The distribution of interleukin-10 (IL-10) promoter polymorphisms in Chinese Han ethnic patients with hepatitis B virus (HBV) infection and hepatocellular carcinoma (HCC) was investigated in this study...
  13. ncbi request reprint The PEX Gene Screen: molecular diagnosis of peroxisome biogenesis disorders in the Zellweger syndrome spectrum
    Steven Steinberg
    Peroxisomal Diseases Laboratory, Kennedy Krieger Institute and Department of Neurology, Johns Hopkins University, Baltimore, MD, USA
    Mol Genet Metab 83:252-63. 2004
    ..This systematic, hierarchical approach to mutation identification is therefore a valuable tool to identify rapidly the molecular etiology of suspected PBD-ZSS disorders...
  14. ncbi request reprint Tissue microarrays in pathological examination of apoptotic acinar cells induced by dexamethasone in the pancreas of rats with severe acute pancreatitis
    Xi Ping Zhang
    Department of General Surgery, Hangzhou First People s Hospital, Hangzhou 310006, China
    Hepatobiliary Pancreat Dis Int 6:527-36. 2007
    ..This study was designed to investigate the influence of dexamethasone on apoptosis of acinar cells in the pancreas of rats with SAP and the protein expression of the apoptosis-regulating genes Bax and Bcl-2...
  15. doi request reprint Risk adjusted auditing of postop complications in gastric cancer patients by POSSUM
    Birendra Kumar Sah
    Department of General Surgery, Rui Jin Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai Institute of Digestive Surgery, Shanghai, China
    Int J Surg 6:311-6. 2008
    ..However, overall complication rate considered being higher if it is recorded according to POSSUM criteria. Modification in POSSUM equation with revised morbidity definition may be more feasible for major operations...
  16. pmc Cardiac dysfunction in aging conscious rats: altered cardiac cytoskeletal proteins as a potential mechanism
    Samuel C Lieber
    Dept of Cell Biology and Molecular Medicine, UMDNJ New Jersey Medical School, 185 South Orange Ave, MSB G 609, Newark, NJ 07103, USA
    Am J Physiol Heart Circ Physiol 295:H860-6. 2008
    ..3-fold), whereas intact desmin decreased by 51%. Thus the cardiomyopathy of aging in old, conscious rats may be due not only to increases in collagen but also to alterations in cytoskeletal proteins...
  17. ncbi request reprint The effects of continuous positive airway pressure on myocardial energetics in patients with heart failure and obstructive sleep apnea
    Keiichiro Yoshinaga
    Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Canada
    J Am Coll Cardiol 49:450-8. 2007
    ..We sought to examine the short-term and longer term (6-week) effects of continuous positive airway pressure (CPAP) on myocardial energetics...
  18. doi request reprint Design, synthesis, and antihepatocellular carcinoma activity of nitric oxide releasing derivatives of oleanolic acid
    Li Chen
    Department of Phytochemistry, Center of Drug Discovery, China Pharmaceutical University, Nanjing 210009, PR China
    J Med Chem 51:4834-8. 2008
    ..Treatment with 8b or 16b significantly inhibited the growth of HCC tumors in vivo. These data provide a proof-in-principle that furoxan/OA hybrids may be used for therapeutic intervention of human liver cancers...
  19. ncbi request reprint [Studies on cytogeography of Pinellia ternata poliploid complex]
    Cheng Bin Chen
    College of Life Sciences, Nankai University, Tianjin 300071, China
    Zhongguo Zhong Yao Za Zhi 31:1405-8. 2006
    ..ternata were investigated in 27 different populations among 16 provinces and regions in China systematically...
  20. ncbi request reprint Status of cytokines in ischemia reperfusion induced heart injury
    Ming Zhang
    Department of Pharmacology, School of Basic Medical Sciences, Jilin University, Changchun, Jilin, China
    Cardiovasc Hematol Disord Drug Targets 8:161-72. 2008
    ....
  21. ncbi request reprint Activation of the cardiac proteasome during pressure overload promotes ventricular hypertrophy
    Christophe Depre
    Department of Cell Biology and Molecular Medicine, UMDNJ, Newark, NJ 07103, USA
    Circulation 114:1821-8. 2006
    ....
  22. ncbi request reprint Distinct responses of lung and spleen dendritic cells to the TLR9 agonist CpG oligodeoxynucleotide
    Li Chen
    Department of Medicine, Pulmonary, Allergy, and Critical Care Division, University of Pittsburgh School of Medicine, 3459 Fifth Avenue, Pittsburgh, PA 15213, USA
    J Immunol 177:2373-83. 2006
    ....
  23. ncbi request reprint Papillary glioneuronal tumor: a clinicopathological and immunohistochemical study of two cases
    Li Chen
    Department of Pathology, Xuanwu Hospital, Capital University of Medical Sciences, Beijing, China
    Neuropathology 26:243-8. 2006
    ..The MIB-1 labeling index was < 3%. The tumor did not recur within the follow-up periods of 50 months and 13 months, and the patient with temporal lobe epilepsy became seizure-free after surgery...
  24. ncbi request reprint Natural killer dendritic cells are an intermediate of developing dendritic cells
    Li Chen
    Department of Pathology, Ohio State University Medical Center, 129 Hamilton Hall, 1645 Neil Avenue, Columbus, OH 43210, USA
    J Leukoc Biol 81:1422-33. 2007
    ..1(+)MHC II(-) and possess strong cytotoxic function yet show a poor ability to present antigen in the steady state. These findings suggest that NKDCs may play a critical role in linking innate and adaptive immunity...
  25. pmc Indoleamine 2,3-dioxygenase in lung dendritic cells promotes Th2 responses and allergic inflammation
    Hui Xu
    Department of Medicine, Division of Pulmonary, Allergy and Critical Care Medicine and Department of Immunology, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Proc Natl Acad Sci U S A 105:6690-5. 2008
    ..Collectively, these data suggest that IDO is not required for the induction of immune tolerance in the airways but plays a role in promoting Th2-mediated allergic airway inflammation via unique effects on lung dendritic cells...
  26. pmc Preoperative localization and minimally invasive management of primary hyperparathyroidism concomitant with thyroid disease
    Yi xiong Zheng
    Department of Surgery, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, China
    J Zhejiang Univ Sci B 8:626-31. 2007
    ..Synchronous treatment of associated thyroid abnormalities is desirable, and open minimally invasive surgical approach with additional resection of isolated ipsilateral thyroid nodules is possible in some of these patients...
  27. ncbi request reprint Effects of large dose of dexamethasone on inflammatory mediators and pancreatic cell apoptosis of rats with severe acute pancreatitis
    Xi Ping Zhang
    Department of General Surgery, Hangzhou First People s Hospital, 261 Huansha Road, Hangzhou 310006, Zhejiang Province, China
    World J Gastroenterol 13:5506-11. 2007
    ..To investigate the influence of high dose of dexamethasone on inflammatory mediators and apoptosis of rats with severe acute pancreatitis (SAP)...
  28. ncbi request reprint A fate map of Tbx1 expressing cells reveals heterogeneity in the second cardiac field
    Tuong Huynh
    Institute of Biosciences and Technology, Texas A and M University Health Sciences Center, Houston, Texas 77030, USA
    Genesis 45:470-5. 2007
    ..Finally, we show that Tbx1(Cre)-positive and Tbx1(Cre)-negative cell descendants occupy discrete domains in the outflow tract throughout development...
  29. ncbi request reprint Rejection of metastatic 4T1 breast cancer by attenuation of Treg cells in combination with immune stimulation
    Li Chen
    Department of Gene and Cell Medicine, Mount Sinai School of Medicine, New York, New York 10029 6574, USA
    Mol Ther 15:2194-202. 2007
    ....
  30. ncbi request reprint [Investigation and analysis of China residents' environmental conservation desire]
    Shi Xiong Cao
    College of Economics and Management, China Agricultural University, Beijing 100094, China
    Ying Yong Sheng Tai Xue Bao 18:2104-10. 2007
    ..The environment policy-making should put more emphasis on developing economics, strengthening education, and improving residents' livelihood...
  31. ncbi request reprint HIV protease inhibitors increase TNF-alpha and IL-6 expression in macrophages: involvement of the RNA-binding protein HuR
    Huiping Zhou
    Department of Microbiology and Immunology, Virginia Commonwealth University, Richmond, VA 23298, United States
    Atherosclerosis 195:e134-43. 2007
    ..Down regulation of HuR expression by siRNA prevented atazanavir-induced increase of TNF-alpha and IL-6. These results suggest that HuR might have an impact on pathophysiological processes of HIV PI-induced atherosclerosis...
  32. pmc Synthesis and anti-inflammatory activities of mono-carbonyl analogues of curcumin
    Guang Liang
    College of Pharmacy, Wenzhou Medical College, Wenzhou, Zhejiang 325035, PR China
    Bioorg Med Chem Lett 18:1525-9. 2008
    ....
  33. pmc Expression of tumor necrosis factor-alpha converting enzyme in liver regeneration after partial hepatectomy
    Xian Ming Lin
    Department of Surgery, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, Zhejiang Province, China
    World J Gastroenterol 14:1353-7. 2008
    ..To study the expression of tumor necrosis factor-alpha converting enzyme (TACE) and evaluate its significance in liver regeneration after partial hepatectomy in vivo...
  34. doi request reprint Spatiotemporal expression of SSeCKS in injured rat sciatic nerve
    Li Chen
    The Jiangsu Province Key Laboratory of Neuroregeneration, Nantong University, Nantong, People s Republic of China
    Anat Rec (Hoboken) 291:527-37. 2008
    ..These findings support the idea that SSeCKS participates in the adaptive response to peripheral nerve injury and may be associated with regeneration...
  35. ncbi request reprint Persistence and dissipation of synthetic pyrethroid pesticides in red soils from the Yangtze River Delta area
    Xiao Zhi Gu
    Institute of Soil Science, Chinese Academy of Sciences, Nanjing 210008, China
    Environ Geochem Health 30:67-77. 2008
    ....
  36. pmc Simvastatin promotes Th2-type responses through the induction of the chitinase family member Ym1 in dendritic cells
    Meenakshi Arora
    Department of Medicine, Division of Pulmonary, Allergy, and Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
    Proc Natl Acad Sci U S A 103:7777-82. 2006
    ..Also, simvastatin was unable to augment Ym1 expression in DCs developed from STAT6-/- or IL-4R alpha-/- mice. Thus, modulation of Ym1 production by DCs identifies a previously undescribed mechanism of Th2 polarization by statin...
  37. ncbi request reprint Exercise training promotes expression of apelin and APJ of cardiovascular tissues in spontaneously hypertensive rats
    Jing Zhang
    Institute of Cardiovascular Research, Peking University First Hospital, Beijing 100034, China
    Life Sci 79:1153-9. 2006
    ....
  38. ncbi request reprint Depressive symptoms and risk factors in Chinese persons with type 2 diabetes
    Ling Xu
    Department of Endocrinology, Qi Lu Hospital, University of Shandong, Jinan 250012, People s Republic of China
    Arch Med Res 35:301-7. 2004
    ..Our objective was to study depressive symptoms and potential risk factors in Chinese persons with type 2 diabetes...
  39. ncbi request reprint The physiology constant database of teen-agers in Beijing
    Wei Qi Wei
    Department of Biomedical Engineering, Institute of Basic Medical Sciences, Peking Union Medical College, Chinese Academy of Medical Sciences, China
    ScientificWorldJournal 4:442-8. 2004
    ..The statistical table, scatter diagram, and histogram of the data are available for both anonym and user according to queries, while only the user can achieve detail, including download data and advanced search...
  40. ncbi request reprint Computationally efficient curve-fitting procedure for large two-dimensional experimental infrared spectroscopic arrays using the Pearson VII model
    Li Chen
    Department of Chemical and Environmental Engineering, 4 Engineering Drive 4, National University of Singapore, Singapore 119260
    Appl Spectrosc 57:331-7. 2003
    ..The procedure holds considerable promise for the curve fitting of massive time-series spectroscopic data, such as that arising from on-line process monitoring of expensive value-added specialty chemical and pharmaceutical syntheses...
  41. ncbi request reprint Proteomic and inducible transgenic approaches to study disease processes
    Prabir Ray
    Dorothy P and Richard P Simmons Center for Research and Education in Interstitial Lung Disease, Division of Pulmonary, Allergy, and Critical Care Medicine and Department of Immunology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA
    Am J Respir Cell Mol Biol 29:S42-6. 2003
  42. ncbi request reprint [Associations of Rsa I polymorphism at the 5' flanking region of CYP2E1 and PON2 148 polymorphism in neonates with preterm delivery]
    Bai yan Wu
    Department of Biology and Genetics, Peking University Health Science Center, Beijing 100083, China
    Yi Chuan Xue Bao 30:577-83. 2003
    ..Furthermore, the gene interaction between Rsa I polymorphism at the 5' flanking region of CYP2E1 and PON2 148 polymorphism in neonates is significantly associated with preterm delivery...
  43. pmc Rad23 promotes the targeting of proteolytic substrates to the proteasome
    Li Chen
    Department of Biochemistry, Robert Wood Johnson Medical School, Piscataway, New Jersey 08854, USA
    Mol Cell Biol 22:4902-13. 2002
    ....
  44. ncbi request reprint Matrix is the site of indirect effects of propranolol on the ion channelopathies in cardiac remodeling by L-thyroxine
    De Zai Dai
    Research Division of Pharmacology, China Pharmaceutical University, Nanjing, China
    J Card Surg 17:439-46. 2002
    ..The benefit of propranolol on the disordered ion channels is mediated by its ability to ameliorate lesions of the matrix...
  45. ncbi request reprint [Non-technical causes of fakes existing in Chinese medicinal material markets]
    Jiyan Chen
    Taihe Hospital of Shiyan, Hubei Province, 442000
    Zhong Yao Cai 25:516-9. 2002
    ....
  46. ncbi request reprint The masticatory efficiency of mandibular implant-supported overdentures as compared with tooth-supported overdentures and complete dentures
    Li Chen
    School of Stomatology, Peking University, Beijing 100081, China
    J Oral Implantol 28:238-43. 2002
    ..The results revealed that the ISO provided the greatest degree of efficiency, followed by the TSO and then the CD group. CME is more correlated to ME and less correlated to EMG...
  47. ncbi request reprint Mutation analysis of PEX7 in 60 probands with rhizomelic chondrodysplasia punctata and functional correlations of genotype with phenotype
    Nancy Braverman
    McKusick Nathans Institute of Genetic Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Hum Mutat 20:284-97. 2002
    ..We find that residual activity of mutant Pex7p and reduced amounts of normal Pex7p are associated with milder and variant phenotypes...
  48. ncbi request reprint [Study on tumorigenic mechanism of human leukemia cell line in nude mice]
    Xiaoping Xu
    Department of Hematology, Changhai Hospital of Second Military Medical University, Shanghai 200433, China
    Zhonghua Xue Ye Xue Za Zhi 23:258-60. 2002
    ..To investigate the tumorigenic mechanisms of human leukemia cell line HL60-n in nude mice...
  49. ncbi request reprint Different contributions of STAT3, ERK1/2, and PI3-K signaling to cardiomyocyte hypertrophy by cardiotrophin-1
    Ze Jun Tian
    Department of Cardiology, Second Hospital of Hebei Medical University, Shijiazhuang 050000, China
    Acta Pharmacol Sin 25:1157-64. 2004
    ....
  50. ncbi request reprint Agrobacterium-mediated transformation of the wetland monocot Typha latifolia L. (Broadleaf cattail)
    Rangaraj Nandakumar
    Department of Bioscience, Salem International University, Salem, WV, 26426 0500, USA
    Plant Cell Rep 23:744-50. 2005
    ..PCR and Southern analyses of transgenic calli and transgenic plants confirmed the presence of the introduced genes. In conclusion, T. latifolia could be genetically transformed by Agrobacterium tumefaciens...
  51. ncbi request reprint Cardioprotective effects of ghrelin and des-octanoyl ghrelin on myocardial injury induced by isoproterenol in rats
    Lian Li
    Institute of Cardiovascular Research, Peking University First Hospital, Beijing 100034, China
    Acta Pharmacol Sin 27:527-35. 2006
    ..To determine the cardioprotective action of ghrelin and des-octanoyl ghrelin in rats with isoproterenol-induced myocardial injury...
  52. ncbi request reprint Pharmacokinetic and pharmacodynamic properties of multiple oral doses of sitagliptin, a dipeptidyl peptidase-IV inhibitor: a double-blind, randomized, placebo-controlled study in healthy male volunteers
    Arthur J Bergman
    Merck and Co, Inc, Whitehouse Station, New Jersey 07065 0900, USA
    Clin Ther 28:55-72. 2006
    ..Sitagliptin is an orally active and selective DPP-IV inhibitor currently in Phase III development for the treatment of type 2 diabetes mellitus...
  53. ncbi request reprint Impaired allogeneic activation and T-helper 1 differentiation of human cord blood naive CD4 T cells
    Li Chen
    Department of Pediatrics and the Immunology Program, Stanford University School of Medicine, Stanford, California 94305, USA
    Biol Blood Marrow Transplant 12:160-71. 2006
    ..Together, these intrinsic limitations in T-cell activation and Th1 differentiation may impair the ability of T cells in CB and the neonate to respond to allogeneic or infectious challenges...
  54. ncbi request reprint Expression of HBcAg mutant with long internal deletion in Saccharomyces cerevisiae and observation of its self-assembly particles by atomic force microscopy (AFM)
    Heng Chen
    School of Life Sciences, Shanghai University, Shanghai 200444, PR China
    Int J Biol Macromol 37:239-48. 2005
    ..These initial results above by AFM analysis were very important for further research on the self-assembly, ultrastructure, subunit interaction and core internal deletion mutant (CIDM) function of HBcAg core particles...
  55. ncbi request reprint Human cytomegalovirus inhibits Akt-mediated eNOS activation through upregulating PTEN (phosphatase and tensin homolog deleted on chromosome 10)
    Ying H Shen
    Division of Cardiothoracic Surgery, Michael E DeBakey Department of Surgery, Adult Cardiac Services, Texas Heart Institute, St Luke s Episcopal Hospital, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA
    Cardiovasc Res 69:502-11. 2006
    ..In the current study, we investigated the effects of HCMV infection on eNOS activation in human aortic endothelial cells (HAECs)...
  56. ncbi request reprint DDT serum concentration and menstruation among young Chinese women
    Aimin Chen
    Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, NC, USA
    Environ Res 99:397-402. 2005
    ..The study largely suggests no association between DDE and DDT concentrations and menstrual cycle characteristics in young Chinese women, though the weak-to-no correlation of DDE with menstrual cycle length merits further study...
  57. ncbi request reprint Preparation and analysis of cSNP chip on hepatocellular carcinoma-related genes
    Juan Wang
    College of Life Sciences, Shenzhen University, Shenzhen 518060, China
    Hepatobiliary Pancreat Dis Int 4:398-402. 2005
    ..In preparing a gene chip for detecting polymorphisms on coding region of genes in hepatocellular carcinoma tissues, some cSNPs are of interest for their potential links with phenotype...
  58. ncbi request reprint Alpha-synuclein phosphorylation controls neurotoxicity and inclusion formation in a Drosophila model of Parkinson disease
    Li Chen
    Department of Pathology, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA
    Nat Neurosci 8:657-63. 2005
    ..Because increased number of inclusion bodies correlates with reduced toxicity, inclusion bodies may protect neurons from alpha-synuclein toxicity...
  59. ncbi request reprint [Combined gene therapy enhances collateral vascularization in coronary artery occlusion swine model]
    Ling yun Zu
    Department of Cardiology, Peking University Third Hospital, Beijing 100034, China
    Zhonghua Nei Ke Za Zhi 43:896-9. 2004
    ..To investigate the efficacy of combined gene transfer of vascular endothelial growth factor (VEGF) and angiotensin-1 (Ang-1) in swine coronary artery occlusion...
  60. pmc Surgical management of gastric stump cancer: a report of 37 cases
    Li Chen
    Department of Surgery, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, China
    J Zhejiang Univ Sci B 6:38-42. 2005
    ..To observe the clinicopathological characteristics of gastric stump cancer (GSC) and evaluate the benefits of radical surgery of GSC...
  61. ncbi request reprint [Study concept of traditional Chinese medicine quality standards]
    Jiyan Chen
    Taihe Hospital of Shiyan, Hubei Province, 442000
    Zhong Yao Cai 25:748-50. 2002
    ..Chinese medicine prepared slice quality was controlled mainly by traditional identification method, secondly by modern analytic approach, improving based on popularization...
  62. ncbi request reprint [Association between alpha-1-antichymotrypsin gene polymorphism and cerebral hemorrhage]
    Yu Fu
    Department of Neurology, Peking University Third Hospital, Beijing 100083, China
    Zhonghua Yi Xue Za Zhi 82:915-7. 2002
    ..To explore the association between alpha-1-antichymotrypsin (ACT) gene A/T polymorphism and cerebral hemorrhage among Chinese people...