Jing Chen

Summary

Publications

  1. pmc Epstein-Barr virus encoded latent membrane protein 1 regulates mTOR signaling pathway genes which predict poor prognosis of nasopharyngeal carcinoma
    Jing Chen
    State Key Laboratory of Oncology in Southern China, Sun Yat sen University Cancer Center, Guangzhou, China
    J Transl Med 8:30. 2010
  2. pmc Identification of 20-hydroxyecdysone late-response genes in the chitin biosynthesis pathway
    Qiong Yao
    State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat Sen University, Guangzhou, China
    PLoS ONE 5:e14058. 2010
  3. doi Functional analysis of two chitinase genes during the pupation and eclosion stages of the beet armyworm Spodoptera exigua by RNA interference
    Daowei Zhang
    State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat Sen University, Guangzhou, China
    Arch Insect Biochem Physiol 79:220-34. 2012
  4. pmc LATS2 is de-methylated and overexpressed in nasopharyngeal carcinoma and predicts poor prognosis
    Yan Zhang
    State Key Laboratory of Oncology in Southern China, Sun Yat sen University Cancer Center, Guangzhou, China
    BMC Cancer 10:538. 2010
  5. doi miR-125b is methylated and functions as a tumor suppressor by regulating the ETS1 proto-oncogene in human invasive breast cancer
    Yan Zhang
    State Key Laboratory of Oncology in Southern China, and Department of Pathology, Sun Yat sen University Cancer Center, Guangzhou, PR China
    Cancer Res 71:3552-62. 2011
  6. doi Microarray analysis of differentially expressed genes between nasopharyngeal carcinoma cell lines 5-8F and 6-10B
    Jia Li
    Cancer Institute, Southern Medical University, Guangzhou, 510515, China
    Cancer Genet Cytogenet 196:23-30. 2010
  7. doi H3K9 methylation is a barrier during somatic cell reprogramming into iPSCs
    Jiekai Chen
    Key Laboratory of Regenerative Biology, South China Institute for Stem Cell Biology and Regenerative Medicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China
    Nat Genet 45:34-42. 2013
  8. pmc Recombinant human endostatin normalizes tumor vasculature and enhances radiation response in xenografted human nasopharyngeal carcinoma models
    Fang Peng
    Department of Radiation Oncology, Sun Yat sen University Cancer Center, Guangzhou, Guangdong Province, China
    PLoS ONE 7:e34646. 2012
  9. pmc Different functions of the insect soluble and membrane-bound trehalase genes in chitin biosynthesis revealed by RNA interference
    Jie Chen
    State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat Sen University, Guangzhou, China
    PLoS ONE 5:e10133. 2010

Detail Information

Publications9

  1. pmc Epstein-Barr virus encoded latent membrane protein 1 regulates mTOR signaling pathway genes which predict poor prognosis of nasopharyngeal carcinoma
    Jing Chen
    State Key Laboratory of Oncology in Southern China, Sun Yat sen University Cancer Center, Guangzhou, China
    J Transl Med 8:30. 2010
    ..The oncoprotein Epstain-Barr Virus (EBV)-encoded latent membrane protein1 (LMP1) modulates the pathological effects of the NF-kappaB, AP-1 and JAK/STAT pathways in nasopharyngeal carcinoma (NPC)...
  2. pmc Identification of 20-hydroxyecdysone late-response genes in the chitin biosynthesis pathway
    Qiong Yao
    State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat Sen University, Guangzhou, China
    PLoS ONE 5:e14058. 2010
    ..However, ecdysone-responsive genes have not been previously characterized in the context of insect chitin biosynthesis...
  3. doi Functional analysis of two chitinase genes during the pupation and eclosion stages of the beet armyworm Spodoptera exigua by RNA interference
    Daowei Zhang
    State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat Sen University, Guangzhou, China
    Arch Insect Biochem Physiol 79:220-34. 2012
    ..For the insects injected with SeChi-h dsRNA, the survival rates were 72.38% and 48.52%, respectively. These results suggest that SeChi and SeChi-h may have different biologic functions during the pupal-adult molting...
  4. pmc LATS2 is de-methylated and overexpressed in nasopharyngeal carcinoma and predicts poor prognosis
    Yan Zhang
    State Key Laboratory of Oncology in Southern China, Sun Yat sen University Cancer Center, Guangzhou, China
    BMC Cancer 10:538. 2010
    ..In this study, we aimed to investigate the expression pattern of LATS2 and its clinicopathological involvement in nasopharyngeal carcinoma to understand its effect on cell survival...
  5. doi miR-125b is methylated and functions as a tumor suppressor by regulating the ETS1 proto-oncogene in human invasive breast cancer
    Yan Zhang
    State Key Laboratory of Oncology in Southern China, and Department of Pathology, Sun Yat sen University Cancer Center, Guangzhou, PR China
    Cancer Res 71:3552-62. 2011
    ..Taken together, our findings point to an important role for miR-125b in the molecular etiology of invasive breast cancer, and they suggest miR-125b as a potential theranostic tool in this disease...
  6. doi Microarray analysis of differentially expressed genes between nasopharyngeal carcinoma cell lines 5-8F and 6-10B
    Jia Li
    Cancer Institute, Southern Medical University, Guangzhou, 510515, China
    Cancer Genet Cytogenet 196:23-30. 2010
    ..Among the gene networks identified, the PTHLH gene was of particular interest. Predicted to regulate the WNT pathway through the DKK1 gene, the PTHLH gene may affect metastasis and apoptosis of NPC and merits further study...
  7. doi H3K9 methylation is a barrier during somatic cell reprogramming into iPSCs
    Jiekai Chen
    Key Laboratory of Regenerative Biology, South China Institute for Stem Cell Biology and Regenerative Medicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China
    Nat Genet 45:34-42. 2013
    ..Our results not only establish pre-iPSCs as an epigenetically stable signpost along the reprogramming road map, but they also provide mechanistic insights into the epigenetic reprogramming of cell fate...
  8. pmc Recombinant human endostatin normalizes tumor vasculature and enhances radiation response in xenografted human nasopharyngeal carcinoma models
    Fang Peng
    Department of Radiation Oncology, Sun Yat sen University Cancer Center, Guangzhou, Guangdong Province, China
    PLoS ONE 7:e34646. 2012
    ....
  9. pmc Different functions of the insect soluble and membrane-bound trehalase genes in chitin biosynthesis revealed by RNA interference
    Jie Chen
    State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat Sen University, Guangzhou, China
    PLoS ONE 5:e10133. 2010
    ..However, no functions of the two trehalases in chitin biosynthesis in insects have yet been reported...