Jian xiong Chen

Summary

Publications

  1. pmc Inhibition of protein tyrosine phosphatase improves angiogenesis via enhancing Ang-1/Tie-2 signaling in diabetes
    Jian xiong Chen
    Department of Pharmacology and Toxicology, University of Mississippi Medical Center, 2500 North State Street, Jackson, MS 39216, USA
    Exp Diabetes Res 2012:836759. 2012
  2. pmc Overexpression of angiopoietin-2 impairs myocardial angiogenesis and exacerbates cardiac fibrosis in the diabetic db/db mouse model
    Jian xiong Chen
    Department of Pharmacology and Toxicology, University of Mississippi Medical Center, Jackson, MS 39216, USA
    Am J Physiol Heart Circ Physiol 302:H1003-12. 2012
  3. pmc Apelin-13 increases myocardial progenitor cells and improves repair postmyocardial infarction
    Lanfang Li
    Department of Pharmacology and Toxicology, University of Mississippi Medical Center, Jackson, Mississippi 39216, USA
    Am J Physiol Heart Circ Physiol 303:H605-18. 2012
  4. pmc Myocardial Injection of Apelin-Overexpressing Bone Marrow Cells Improves Cardiac Repair via Upregulation of Sirt3 after Myocardial Infarction
    Lanfang Li
    Department of Pharmacology and Toxicology, University of Mississippi Medical Center, Jackson, Mississippi, United States of America
    PLoS ONE 8:e71041. 2013
  5. pmc Isoprostanes as physiological mediators of transition to newborn life: novel mechanisms regulating patency of the term and preterm ductus arteriosus
    Jian xiong Chen
    Department of Pharmacology and Toxicology, University of Mississippi Medical Center, Jackson, USA
    Pediatr Res 72:122-8. 2012
  6. pmc Overexpression of angiopoietin-1 increases CD133+/c-kit+ cells and reduces myocardial apoptosis in db/db mouse infarcted hearts
    Heng Zeng
    Department of Pharmacology and Toxicology, University of Mississippi Medical Center, Jackson, Mississippi, USA
    PLoS ONE 7:e35905. 2012

Collaborators

  • Lanfang Li
  • Heng Zeng
  • Xuwei Hou
  • Xiaochen He

Detail Information

Publications6

  1. pmc Inhibition of protein tyrosine phosphatase improves angiogenesis via enhancing Ang-1/Tie-2 signaling in diabetes
    Jian xiong Chen
    Department of Pharmacology and Toxicology, University of Mississippi Medical Center, 2500 North State Street, Jackson, MS 39216, USA
    Exp Diabetes Res 2012:836759. 2012
    ....
  2. pmc Overexpression of angiopoietin-2 impairs myocardial angiogenesis and exacerbates cardiac fibrosis in the diabetic db/db mouse model
    Jian xiong Chen
    Department of Pharmacology and Toxicology, University of Mississippi Medical Center, Jackson, MS 39216, USA
    Am J Physiol Heart Circ Physiol 302:H1003-12. 2012
    ..Our data demonstrate that Ang-2 increases endothelial apoptosis, sensitizes myocardial microvascular inflammation, and promotes cardiac fibrosis and thus contributes to loss of capillary density in diabetic diseases...
  3. pmc Apelin-13 increases myocardial progenitor cells and improves repair postmyocardial infarction
    Lanfang Li
    Department of Pharmacology and Toxicology, University of Mississippi Medical Center, Jackson, Mississippi 39216, USA
    Am J Physiol Heart Circ Physiol 303:H605-18. 2012
    ..Apelin-13 increases angiogenesis and improves cardiac repair post-MI by a mechanism involving the upregulation of SDF-1α/CXCR-4 and homing of vascular PCs...
  4. pmc Myocardial Injection of Apelin-Overexpressing Bone Marrow Cells Improves Cardiac Repair via Upregulation of Sirt3 after Myocardial Infarction
    Lanfang Li
    Department of Pharmacology and Toxicology, University of Mississippi Medical Center, Jackson, Mississippi, United States of America
    PLoS ONE 8:e71041. 2013
    ..These data suggest that apelin improves BMCs therapy on cardiac repair and systolic function in post-MI mice. Upregulation of Sirt3 may contribute to the protective effect of apelin-BMCs therapy. ..
  5. pmc Isoprostanes as physiological mediators of transition to newborn life: novel mechanisms regulating patency of the term and preterm ductus arteriosus
    Jian xiong Chen
    Department of Pharmacology and Toxicology, University of Mississippi Medical Center, Jackson, USA
    Pediatr Res 72:122-8. 2012
    ..We hypothesized that isoprostanes regulate ductus arteriosus (DA) function during postnatal vascular transition...
  6. pmc Overexpression of angiopoietin-1 increases CD133+/c-kit+ cells and reduces myocardial apoptosis in db/db mouse infarcted hearts
    Heng Zeng
    Department of Pharmacology and Toxicology, University of Mississippi Medical Center, Jackson, Mississippi, USA
    PLoS ONE 7:e35905. 2012
    ..Our data strongly suggest that Ang-1 attenuates cardiac apoptosis and promotes cardiac repair by a mechanism involving in promoting CD133(+)/c-kit(+) cells and angiogenesis in diabetic db/db mouse infarcted hearts...