Gang Chen

Summary

Publications

  1. ncbi request reprint Effects of losartan and irbesartan on serum uric acid in hypertensive patients with hyperuricaemia in Chinese population
    A Dang
    Cardiovascular Institute and Fu Wai Hospital, Peking Union Medical College and Chinese Academy of Medical Science, Beijing, Peoples Republic of China
    J Hum Hypertens 20:45-50. 2006
  2. pmc Striatal involvement in human alcoholism and alcohol consumption, and withdrawal in animal models
    Gang Chen
    Department of Behavioral Neuroscience, Oregon Health and Science University, Portland, Oregon, USA
    Alcohol Clin Exp Res 35:1739-48. 2011
  3. pmc Primary Leiomyoma of the pleura
    Xiaoming Qiu
    Department of Lung Cancer Surgery, Tianjin Key Laboratory of Lung Cancer Metastasis and Tumor Microenvironment, Tianjin Lung Cancer Institute, Tianjin Medical University General Hospital, China
    World J Surg Oncol 9:76. 2011
  4. pmc Association between serum endogenous secretory receptor for advanced glycation end products and risk of type 2 diabetes mellitus with combined depression in the Chinese population
    Gang Chen
    Department of Endocrinology, Fujian Provincial Hospital, Fujian Medical University, Fuzhou, China
    Diabetes Technol Ther 14:936-42. 2012
  5. pmc Impact of family history of diabetes on β-cell function and insulin resistance among Chinese with normal glucose tolerance
    Gang Chen
    Department of Endocrinology, Fujian Provincial Hospital, Fujian Medical University, Fuzhou, China
    Diabetes Technol Ther 14:463-8. 2012
  6. doi request reprint Body fat distribution and their associations with cardiovascular risk, insulin resistance and β-cell function: are there differences between men and women?
    G Chen
    Department of Endocrinology, Fujian Provincial Hospital, Fujian Medical University, Fuzhou, China
    Int J Clin Pract 65:592-601. 2011
  7. doi request reprint Construction of NF-κB-targeting RNAi adenovirus vector and the effect of NF-κB pathway on proliferation and apoptosis of vascular endothelial cells
    Gang Chen
    Department of Endocrinology, Fujian Provincial Hospital, Fujian Medical University, Fuzhou 350001, China
    Mol Biol Rep 38:3089-94. 2011
  8. doi request reprint Overweight, obesity, and their associations with insulin resistance and β-cell function among Chinese: a cross-sectional study in China
    Gang Chen
    Department of Endocrinology, Fujian Provincial Hospital, Fujian Medical University, Box 4 704, Fuzhou 350001, China
    Metabolism 59:1823-32. 2010
  9. doi request reprint Associations between cardiovascular risk, insulin resistance, beta-cell function and thyroid dysfunction: a cross-sectional study in She ethnic minority group of Fujian Province in China
    Gang Chen
    Department of Endocrinology, Fujian Provincial Hospital, Fujian Medical University, PO Box 4 704, 92 Huqian Road, Fuzhou 350001, Fujian, People s Republic of China
    Eur J Endocrinol 163:775-82. 2010
  10. doi request reprint The correlation between the oral glucose tolerance test 30-minutes plasma glucose and risk factors for diabetes and cardiovascular diseases: a cross-sectional epidemiological study of diabetes in Fujian Province in the South-East of China
    G Chen
    Department of Endocrinology, Fujian Provincial Hospital, Fujian Medical University, Fuzhou, Fujian, China
    J Endocrinol Invest 34:e115-20. 2011

Collaborators

Detail Information

Publications40

  1. ncbi request reprint Effects of losartan and irbesartan on serum uric acid in hypertensive patients with hyperuricaemia in Chinese population
    A Dang
    Cardiovascular Institute and Fu Wai Hospital, Peking Union Medical College and Chinese Academy of Medical Science, Beijing, Peoples Republic of China
    J Hum Hypertens 20:45-50. 2006
    ..Therapy with losartan decreased SUA levels significantly more than irbesartan in Chinese patients with hypertension and elevated SUA levels, demonstrating the unique uricosuric effect of this ARB in this ethnic group...
  2. pmc Striatal involvement in human alcoholism and alcohol consumption, and withdrawal in animal models
    Gang Chen
    Department of Behavioral Neuroscience, Oregon Health and Science University, Portland, Oregon, USA
    Alcohol Clin Exp Res 35:1739-48. 2011
    ..Different regions of the striatum may have distinct roles in acute intoxication, alcohol seeking, dependence, and withdrawal...
  3. pmc Primary Leiomyoma of the pleura
    Xiaoming Qiu
    Department of Lung Cancer Surgery, Tianjin Key Laboratory of Lung Cancer Metastasis and Tumor Microenvironment, Tianjin Lung Cancer Institute, Tianjin Medical University General Hospital, China
    World J Surg Oncol 9:76. 2011
    ..The patient was followed and has been disease-free for over 15 months. This is the first report of primary leiomyoma of the pleura in China. A review of the literature on primary leiomyoma of the pleura is presented...
  4. pmc Association between serum endogenous secretory receptor for advanced glycation end products and risk of type 2 diabetes mellitus with combined depression in the Chinese population
    Gang Chen
    Department of Endocrinology, Fujian Provincial Hospital, Fujian Medical University, Fuzhou, China
    Diabetes Technol Ther 14:936-42. 2012
    ..This study investigated the role of serum esRAGE in patients with type 2 diabetes mellitus with depression in the Chinese population...
  5. pmc Impact of family history of diabetes on β-cell function and insulin resistance among Chinese with normal glucose tolerance
    Gang Chen
    Department of Endocrinology, Fujian Provincial Hospital, Fujian Medical University, Fuzhou, China
    Diabetes Technol Ther 14:463-8. 2012
    ..This study investigated the impact of family history of diabetes (FHD) on β-cell function among Chinese with normal glucose tolerance...
  6. doi request reprint Body fat distribution and their associations with cardiovascular risk, insulin resistance and β-cell function: are there differences between men and women?
    G Chen
    Department of Endocrinology, Fujian Provincial Hospital, Fujian Medical University, Fuzhou, China
    Int J Clin Pract 65:592-601. 2011
    ..The objective was to examine the independent and gender-specific effects of WC and BMI on CVD risk factors, insulin resistance and β-cell function...
  7. doi request reprint Construction of NF-κB-targeting RNAi adenovirus vector and the effect of NF-κB pathway on proliferation and apoptosis of vascular endothelial cells
    Gang Chen
    Department of Endocrinology, Fujian Provincial Hospital, Fujian Medical University, Fuzhou 350001, China
    Mol Biol Rep 38:3089-94. 2011
    ..We used a NF-κB/p65-targeting RNAi adenovirus to demonstrate the role of the NF-κB pathway in the regulation of ECV304 cell proliferation. This adenovirus may serve as an important tool to study the NF-κB pathway...
  8. doi request reprint Overweight, obesity, and their associations with insulin resistance and β-cell function among Chinese: a cross-sectional study in China
    Gang Chen
    Department of Endocrinology, Fujian Provincial Hospital, Fujian Medical University, Box 4 704, Fuzhou 350001, China
    Metabolism 59:1823-32. 2010
    ..It is imperative that the whole society pay more attention to the identification and intervention of overweight and obesity to prevent obesity-related diseases at the very early stage...
  9. doi request reprint Associations between cardiovascular risk, insulin resistance, beta-cell function and thyroid dysfunction: a cross-sectional study in She ethnic minority group of Fujian Province in China
    Gang Chen
    Department of Endocrinology, Fujian Provincial Hospital, Fujian Medical University, PO Box 4 704, 92 Huqian Road, Fuzhou 350001, Fujian, People s Republic of China
    Eur J Endocrinol 163:775-82. 2010
    ..To investigate the associations between cardiovascular risk, insulin resistance (IR), β-cell function and thyroid dysfunction in She ethnic minority group in China...
  10. doi request reprint The correlation between the oral glucose tolerance test 30-minutes plasma glucose and risk factors for diabetes and cardiovascular diseases: a cross-sectional epidemiological study of diabetes in Fujian Province in the South-East of China
    G Chen
    Department of Endocrinology, Fujian Provincial Hospital, Fujian Medical University, Fuzhou, Fujian, China
    J Endocrinol Invest 34:e115-20. 2011
    ..To investigate the correlation between abnormal oral glucose tolerance test (OGTT) 30-min plasma glucose (PG) and risk factors and metabolic abnormalities of diabetes and cardiovascular diseases (CVD)...
  11. doi request reprint The effect of NF-κB pathway on proliferation and apoptosis of human umbilical vein endothelial cells induced by intermittent high glucose
    Gang Chen
    Department of Endocrinology, Fujian Provincial Hospital, Fujian Medical University, Fuzhou, 350001, China
    Mol Cell Biochem 347:127-33. 2011
    ..Intermittent HG reduces HUVECs proliferation with a concomitant increase in apoptosis. Knockdown of NF-κB/p65 partly protected HUVECs from proliferation inhibition and may reduce apoptosis...
  12. pmc Serum level of endogenous secretory receptor for advanced glycation end products and other factors in type 2 diabetic patients with mild cognitive impairment
    Gang Chen
    Department of Endocrinology, Fujian Provincial Hospital, Fujian Medical University, Fuzhou, China
    Diabetes Care 34:2586-90. 2011
    ....
  13. doi request reprint Cardiovascular disease (CVD) risk, insulin resistance and β-cell function in prehypertension population of China
    Gang Chen
    Department of Endocrinology, Fujian Provincial Hospital, Fujian Medical University, Fuzhou 350001, China
    Atherosclerosis 217:279-85. 2011
    ..To explore the cardiovascular disease (CVD) risk in prehypertensive subjects and evaluate whether high blood pressure (BP) is associated with insulin resistance (IR) and β-cell dysfunction...
  14. doi request reprint Ablation of NF-kappaB expression by small interference RNA prevents the dysfunction of human umbilical vein endothelial cells induced by high glucose
    Gang Chen
    Department of Endocrinology, Fujian Medical University, Fujian, China
    Endocrine 35:63-74. 2009
    ..These findings may explain how hyperglycemia promotes dysfunction of ECs and could elucidate a potential new target for therapeutic interventions...
  15. doi request reprint Retrospective analysis of thyroid nodules by clinical and pathological characteristics, and ultrasonographically detected calcification correlated to thyroid carcinoma in South China
    G Chen
    Department of Endocrinology, Fujian Provincial Hospital, Fujian Medical University, Fuzhou, PR China
    Eur Surg Res 42:137-42. 2009
    ..To investigate the clinical and pathological characteristics of thyroid nodules, as well as to evaluate the significance of ultrasonographically detected thyroid calcification in the diagnosis of thyroid carcinomas...
  16. doi request reprint Prevalence and risk factors associated with prehypertension and hypertension in the Chinese She population
    Yinghua Lin
    Department of Endocrinology, Ningde Municipal Hospital, Ningde, PR China
    Kidney Blood Press Res 35:305-13. 2012
    ..Little is known about the prevalence and cardiovascular risk factors for prehypertension and hypertension in the She ethnic minority population of Fujian province in China...
  17. doi request reprint High FFA-induced proliferation and apoptosis in human umbilical vein endothelial cell partly through Wnt/beta-catenin signal pathway
    Penli Zhu
    Department of Endocrinology, Fujian Provincial Hospital, Fujian Medical University, Fuzhou, Fujian, China
    Mol Cell Biochem 338:123-31. 2010
    ..It may be concluded that the RNAi adenovirus specific to GSK-3beta may partly protect HUVECs from apoptosis induced by FFAs, probably through the up-regulation of the Wnt/beta-catenin signal pathway...
  18. doi request reprint Regulation of GSK-3 beta in the proliferation and apoptosis of human thyrocytes investigated using a GSK-3 beta-targeting RNAi adenovirus expression vector: involvement the Wnt/beta-catenin pathway
    Gang Chen
    Department of Endocrinology, Fujian Provincial Hospital, Fujian Medical University, 350001 Fuzhou, China
    Mol Biol Rep 37:2773-9. 2010
    ..It is concluded that the Wnt/beta-catenin pathway plays a significant role in the regulation of the proliferation of primary human thyrocytes...
  19. pmc Diabetes and its chronic complications in the She ethnic minority group of China
    Yinghua Lin
    Department of Endocrinology, Ningde Municipal Hospital, Fujian Medical University, Ningde, China
    Diabetes Technol Ther 14:430-9. 2012
    ..The present study investigated the prevalence of type 2 diabetes and associated risk factors in the adult population of She nationals...
  20. doi request reprint Association study of genetic variants of 17 diabetes-related genes/loci and cardiovascular risk and diabetic nephropathy in the Chinese She population
    Gang Chen
    Department of Endocrinology, Fujian Provincial Hospital, Fujian Medical University, Fujian Provincial Hospital Key Laboratory of Endocrinology, Fuzhou, China
    J Diabetes 5:136-45. 2013
    ..Genetic determinations are important in type 2 diabetes (T2DM) pathology. We investigated associations between genetic variants of 17 diabetes-related genes/loci, T2DM and diabetic complications in Chinese She subjects...
  21. doi request reprint Genetic variations in CYP17A1, CACNB2 and PLEKHA7 are associated with blood pressure and/or hypertension in She ethnic minority of China
    Yinghua Lin
    Department of Endocrinology, Ningde Municipal Hospital, Ningde 352100, China
    Atherosclerosis 219:709-14. 2011
    ..The present study was to investigate whether some variations were associated with BP traits and hypertension or even prehypertension in adult She ethnic minority of China...
  22. doi request reprint Adiponectin inhibits KISS1 gene transcription through AMPK and specificity protein-1 in the hypothalamic GT1-7 neurons
    Jun Ping Wen
    Department of Endocrinology, Fujian Provincial Hospital, Fujian Medical University, Fuzhou 350001, China
    J Endocrinol 214:177-89. 2012
    ..In conclusion, our results provide the first evidence that adiponectin reduces Kiss1 gene transcription in GT1-7 cells through activation of AMPK and subsequently decreased translocation of SP1...
  23. doi request reprint Clinical analysis of 249 cases of adrenal tumors in a Chinese hospital
    Gang Chen
    Department of Endocrinology, Fujian Provincial Hospital, Fujian Medical University, Fuzhou, PR China chengang18 yahoo com
    Urol Int 85:270-5. 2010
    ..This study was designed to evaluate the clinical and pathological characteristics of adrenal masses...
  24. ncbi request reprint [Construction of GSK-3beta-targeting RNAi adenovirus vector and the influence of Wnt/beta-catenin pathway in proliferation of human thyrocytes]
    Gang Chen
    Department of Endocrinology, Fujian Provincial Hospital, Fujian Medical University, Fuzhou 350001, China
    Zhonghua Yi Xue Za Zhi 88:2821-5. 2008
    ....
  25. doi request reprint Associations between age at menarche and menopause with cardiovascular disease, diabetes, and osteoporosis in Chinese women
    Changsheng Qiu
    Department of Osteology, Wuyishan Municipal Hospital, Fujian Provincial Hospital, Wuyishan, 354300, China
    J Clin Endocrinol Metab 98:1612-21. 2013
    ..Ages at menarche and menopause are associated with cardiovascular disease (CVD), diabetes, and osteoporosis in Caucasian women, but associations remain unexplored in Chinese women...
  26. pmc Associations of green tea and rock tea consumption with risk of impaired fasting glucose and impaired glucose tolerance in Chinese men and women
    Huibin Huang
    Department of Endocrinology, Fujian Provincial Hospital Key Laboratory of Endocrinology, Fujian Medical University, Fuzhou, Fujian, China
    PLoS ONE 8:e79214. 2013
    ..To explore the associations of green tea and rock tea consumption with risk of impaired fasting glucose (IFG) and impaired glucose tolerance (IGT)...
  27. ncbi request reprint A ratio test in active control non-inferiority trials with a time-to-event endpoint
    Yong Cheng Wang
    Biostatistics, Centocor, Inc, Malvern, Pennsylvania 19355, USA
    J Biopharm Stat 16:151-64. 2006
    ..The demand on sample size is much reduced. In most commonly encountered situations, the sample size required is less than half of those needed by either the fixed margin approach or Rothmann's method...
  28. doi request reprint Si rib waveguide photodetector with an ordered array of Ge islands for 1.5 microm
    Ventsislav Lavchiev
    Institute for Semiconductor and Solid State Physics, Johannes Kepler University, A 4040 Linz, Austria
    Opt Lett 34:3785-7. 2009
    ..6 mum at 300 K. The absorption length of approximately 135 microm (at 1/e decrease of intensity) at lambda=1.55 microm along the waveguide allows for relatively small-size devices for all-on-one-platform integration...
  29. doi request reprint A pilot study of using multiphoton microscopy to diagnose gastric cancer
    Jun Yan
    Department of Surgery, Fujian Provincial Tumor Hospital, and Ministry of Education, Fujian Normal University, Fuzhou, 350014, China
    Surg Endosc 25:1425-30. 2011
    ....
  30. pmc Prevalence of hypertension in china: a cross-sectional study
    Yun Gao
    Department of Endocrinology, West China Hospital, Sichuan University, Chengdu, People s Republic of China
    PLoS ONE 8:e65938. 2013
    ..The present study aimed to assess the prevalence of hypertension among Chinese adults...
  31. doi request reprint Globular adiponectin regulates energy homeostasis through AMP-activated protein kinase-acetyl-CoA carboxylase (AMPK/ACC) pathway in the hypothalamus
    Jun Ping Wen
    Department of Endocrinology, Fujian Provincial Hospital, Fujian Medical University, Fuzhou, China
    Mol Cell Biochem 344:109-15. 2010
    ..Together these findings suggest that adiponectin regulated energy homeostasis through the AMPK/ACC pathway but not the JAK/STAT3 pathway in the hypothalamus...
  32. doi request reprint Livin abrogates apoptosis of SPC-A1 cell by regulating JNKI signaling pathway
    Yu Sheng Chen
    Department of Respiratory Medicine, Fujian Provincial Hospital, 350001, Fuzhou, Fujian, People s Republic of China
    Mol Biol Rep 37:2241-7. 2010
    ..The results suggest that livin may exert anti-apoptotic action on SPC-A1 by activating JNK1 signaling pathway and inhibiting caspase-3 activation...
  33. pmc Nuclear TK1 expression is an independent prognostic factor for survival in pre-malignant and malignant lesions of the cervix
    Gang Chen
    Department of Pathology, Fujian Provincial Cancer Hospital, Teaching Hospital of Fujian Medical University, Fuzhou, Fujian 350014, China
    BMC Cancer 13:249. 2013
    ..Here we investigate for the first time the use of TK1 expression as a prognostic factor for patients with premalignant and malignant lesions of the uterine cervix...
  34. doi request reprint Angiomatoid fibrous histiocytoma: unusual sites and unusual morphology
    Gang Chen
    Department of Pathology, Fujian Provincial Tumor Hospital, Fuzhou, Fujian, China
    Mod Pathol 24:1560-70. 2011
    ....
  35. doi request reprint Diagnostic validity of human papillomavirus E6/E7 mRNA test in cervical cytological samples
    Tong yu Liu
    Fujian Provincial Tumor Hospital, Teaching Hospital of Fujian Medical University, Fuzhou, Fujian 350014, China
    J Virol Methods 196:120-5. 2014
    ..Studies composed of large population-based samples of women and with rigorous disease ascertainment, are needed to establish the optimal cut-off point based on ROC curve analysis. ..
  36. pmc Association of genetic variants with isolated fasting hyperglycaemia and isolated postprandial hyperglycaemia in a Han Chinese population
    Xiaomu Kong
    Department of Endocrinology, Key Laboratory of Diabetes Prevention and Control, China Japan Friendship Hospital, Beijing, China
    PLoS ONE 8:e71399. 2013
    ..In present study, we aimed to investigate the association of genome-wide association study-validated genetic variants and IFH or IPH in Han Chinese...
  37. pmc Discrimination of gastric cancer from normal by serum RNA based on surface-enhanced Raman spectroscopy (SERS) and multivariate analysis
    Yanping Chen
    Teaching Hospital of Fujian Medical University, Fuzhou, China
    Med Phys 39:5664-8. 2012
    ..Here, the authors explore the feasibility of discriminating cancer patients from healthy controls by serum RNA detection based on surface-enhanced Raman spectroscopy (SERS) and multivariate analysis...
  38. ncbi request reprint [Effects of captopril on myocardial tissue energy metabolism and inflammation in rats with diabetic cardiomyopathy]
    Gang Chen
    Department of Endocrinology, Fujian Provincial Hospital, Fuzhou 350001, China
    Di Yi Jun Yi Da Xue Xue Bao 24:827-8, 831. 2004
    ..To study the protective mechanism of captopril in diabetic cardiomyopathy by means of DNA microarray...
  39. doi request reprint Diabetes, pre-diabetes and associated risks on Minnesota code-indicated major electrocardiogram abnormality among Chinese: a cross-sectional diabetic study in Fujian province, southeast China
    L Lin
    Department of Endocrinology, Fujian Provincial Hospital, Fujian Medical University, Fuzhou, China
    Obes Rev 10:420-30. 2009
    ..Even slightly elevated PG levels may predict early cardiovascular events...
  40. ncbi request reprint [Relationship between epidemiology of HIV-1 infection and HIV-1 subtypes in Fujian province]
    Y Yan
    Fujian Provincial Epidemic and Prevention Station, Fuzhou 350001, China
    Zhonghua Liu Xing Bing Xue Za Zhi 22:428-31. 2001
    ..CONCLUSION: HIV prevalent rate has been increasing in Fujian with major transmission route of heterosexual contact. The dominant strain of HIV-1 was subtype E...