Research Topics

Zeliang Chen



  1. Xu H, Zhang Q, Guan H, Zhong Y, Jiang F, Chen Z, et al. High Incidence of a Novel Rickettsia Genotype in Parasitic Haemaphysalis longicornis from China-North Korea Border. Sci Rep. 2019;9:5373 pubmed publisher
    ..Considering the geographical and biological situations of the sampling sites, more extensive surveillance and risk evaluation of the tick species and tick-borne diseases are required. ..
  2. Liu M, Han X, Yao L, Zhang W, Liu B, Chen Z. Development and application of a simple recombinase polymerase amplification assay for rapid point-of-care detection of feline herpesvirus type 1. Arch Virol. 2019;164:195-200 pubmed publisher
    ..These results indicate that RPA-FLD-FHV is applicable for clinical use. The RPA-FLD-FHV assay is a simple, rapid, and reliable method for point-of-care diagnosis of FHV-1 infection. ..
  3. Ren H, Yang M, Zhang G, Liu S, Wang X, Ke Y, et al. Development of a rapid recombinase polymerase amplification assay for detection of Brucella in blood samples. Mol Cell Probes. 2016;30:122-4 pubmed publisher
    ..The assay could detect as few as 3 copies of Brucella per reaction within 20 min. Bruce-RPA represents a candidate point-of-care diagnosis assay for human brucellosis. ..
  4. Ke Y, Li W, Wang Y, Yang M, Guo J, Zhan S, et al. Inhibition of TLR4 signaling by Brucella TIR-containing protein TcpB-derived decoy peptides. Int J Med Microbiol. 2016;306:391-400 pubmed publisher
  5. Li W, Ke Y, Wang Y, Yang M, Gao J, Zhan S, et al. Brucella TIR-like protein TcpB/Btp1 specifically targets the host adaptor protein MAL/TIRAP to promote infection. Biochem Biophys Res Commun. 2016;477:509-14 pubmed publisher
    ..melitensis. Our results confirm that TcpB specifically targets MAL/TIRAP to disrupt downstream signaling pathways and promote intra-host survival of Brucella spp. ..
  6. Yang M, Ke Y, Zhang W, Liu C, Yang R, Chen Z. RT-PCR using glycoprotein target is more sensitive for the detection of Ebola virus in clinical samples. Diagn Microbiol Infect Dis. 2017;87:235-237 pubmed publisher
    ..In addition, the positive samples in the RT-PCR assay targeting GP showed lower cycle threshold values and higher virus loads than NP gene. ..