R Chavez-Valdez

Summary

Publications

  1. pmc Programmed Necrosis: A Prominent Mechanism of Cell Death following Neonatal Brain Injury
    Raul Chavez-Valdez
    Neonatal Research Laboratory, Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD 21287 3200, USA
    Neurol Res Int 2012:257563. 2012
  2. pmc Opioids and clonidine modulate cytokine production and opioid receptor expression in neonatal immune cells
    R Chavez-Valdez
    Department of Pediatrics, Division of Neonatology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    J Perinatol 33:374-82. 2013
  3. ncbi request reprint Necrostatin-1 attenuates mitochondrial dysfunction in neurons and astrocytes following neonatal hypoxia-ischemia
    R Chavez-Valdez
    Department of Pediatrics, Division of Neonatology, Johns Hopkins Medical Institutions, Johns Hopkins Hospital, 600 N Wolfe Street, CMSC 6 104, Baltimore, MD 21287, USA
    Neuroscience 219:192-203. 2012
  4. doi request reprint Sexual dimorphism in BDNF signaling after neonatal hypoxia-ischemia and treatment with necrostatin-1
    R Chavez-Valdez
    Department of Pediatrics, Neonatal Research Laboratory, Johns Hopkins University School of Medicine, 600 North Wolfe Street, CMSC 6 104, Baltimore, MD 21287, USA Electronic address
    Neuroscience 260:106-19. 2014

Detail Information

Publications4

  1. pmc Programmed Necrosis: A Prominent Mechanism of Cell Death following Neonatal Brain Injury
    Raul Chavez-Valdez
    Neonatal Research Laboratory, Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD 21287 3200, USA
    Neurol Res Int 2012:257563. 2012
    ..There are still more questions than answers, yet the fascinating new perspectives provided by the understanding of programmed necrosis in the developing brain may lay the foundation for new therapies for neonatal HI...
  2. pmc Opioids and clonidine modulate cytokine production and opioid receptor expression in neonatal immune cells
    R Chavez-Valdez
    Department of Pediatrics, Division of Neonatology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    J Perinatol 33:374-82. 2013
    ..Therefore, our objective is to study how clinically relevant concentrations of different opioids and clonidine change cytokine levels in cultured whole blood from preterm and full-term infants...
  3. ncbi request reprint Necrostatin-1 attenuates mitochondrial dysfunction in neurons and astrocytes following neonatal hypoxia-ischemia
    R Chavez-Valdez
    Department of Pediatrics, Division of Neonatology, Johns Hopkins Medical Institutions, Johns Hopkins Hospital, 600 N Wolfe Street, CMSC 6 104, Baltimore, MD 21287, USA
    Neuroscience 219:192-203. 2012
    ..We conclude that Nec-1 immediately after HI, is strongly mitoprotective and prevents secondary energy failure by blocking early NO• accumulation, glutathione oxidation and attenuating mitochondrial dysfunction...
  4. doi request reprint Sexual dimorphism in BDNF signaling after neonatal hypoxia-ischemia and treatment with necrostatin-1
    R Chavez-Valdez
    Department of Pediatrics, Neonatal Research Laboratory, Johns Hopkins University School of Medicine, 600 North Wolfe Street, CMSC 6 104, Baltimore, MD 21287, USA Electronic address
    Neuroscience 260:106-19. 2014
    ..The biological significance of ERα predominance and its correlation with BDNF levels is still unclear. ..