Marietta Charakida

Summary

Publications

  1. doi request reprint Increased arterial stiffness in HIV-infected children: risk factors and antiretroviral therapy
    Marietta Charakida
    Institute of Child Health, University College London, London, UK
    Antivir Ther 14:1075-9. 2009
  2. doi request reprint Drug treatment of obesity in the cardiovascular patient
    Marietta Charakida
    Vascular Physiology Unit, Institute of Child Health, London, UK
    Curr Opin Cardiol 28:584-91. 2013
  3. ncbi request reprint Infections and atheromatous plaque: current therapeutic implications
    Marietta Charakida
    Vascular Physiology Unit, Institute of Child Health, Great Ormond Street Hospital, London, WC1EH, UK
    Curr Pharm Des 19:1638-50. 2013
  4. ncbi request reprint Childhood obesity and vascular phenotypes: a population study
    Marietta Charakida
    Vascular Physiology Unit, National Centre for Cardiovascular Disease Prevention and Outcomes, London, United Kingdom
    J Am Coll Cardiol 60:2643-50. 2012
  5. ncbi request reprint Inflammatory disorders and atherosclerosis: new therapeutic approaches
    Marietta Charakida
    Vascular Physiology Unit, Institute of Child Health, Great Ormond Street Hospital, London, WC1EH, UK
    Curr Pharm Des 17:4111-20. 2011
  6. doi request reprint Vascular abnormalities, paraoxonase activity, and dysfunctional HDL in primary antiphospholipid syndrome
    Marietta Charakida
    Department of Vascular Physiology, The Institute of Child Health, University College London, 34 Great Ormond St, London WC1N 1EH, England
    JAMA 302:1210-7. 2009
  7. pmc Determinants of vascular phenotype in a large childhood population: the Avon Longitudinal Study of Parents and Children (ALSPAC)
    Ann E Donald
    Vascular Physiology Unit, Institute of Child Health, University College London, 30 Guilford Street, London WC1N 1EH, UK
    Eur Heart J 31:1502-10. 2010
  8. pmc Adipose and height growth through childhood and blood pressure status in a large prospective cohort study
    Alexander Jones
    Vascular Physiology Unit, University College London Institute of Cardiovascular Science, London, UK
    Hypertension 59:919-25. 2012
  9. pmc Adiposity and cardiovascular risk factors in a large contemporary population of pre-pubertal children
    Emanuela Falaschetti
    Vascular Physiology Unit, Institute of Child Health, 30 Guilford Street, London WC1N 1EH, UK
    Eur Heart J 31:3063-72. 2010
  10. doi request reprint Endothelial response to childhood infection: the role of mannose-binding lectin (MBL)
    Marietta Charakida
    Vascular Physiology Unit, Institute of Child Health, University College London, 34 Great Ormond Street, London, UK
    Atherosclerosis 208:217-21. 2010

Detail Information

Publications23

  1. doi request reprint Increased arterial stiffness in HIV-infected children: risk factors and antiretroviral therapy
    Marietta Charakida
    Institute of Child Health, University College London, London, UK
    Antivir Ther 14:1075-9. 2009
    ..The relationship between HIV infection and treatment and arterial stiffness has not been evaluated in children...
  2. doi request reprint Drug treatment of obesity in the cardiovascular patient
    Marietta Charakida
    Vascular Physiology Unit, Institute of Child Health, London, UK
    Curr Opin Cardiol 28:584-91. 2013
    ..Pharmacotherapy is frequently advocated as part of a weight loss strategy. In this review, we will discuss the antiobesity drugs with Food and Drug Administration approval and their cardiovascular implications...
  3. ncbi request reprint Infections and atheromatous plaque: current therapeutic implications
    Marietta Charakida
    Vascular Physiology Unit, Institute of Child Health, Great Ormond Street Hospital, London, WC1EH, UK
    Curr Pharm Des 19:1638-50. 2013
    ..Efforts to prevent infection with vaccination or treat specific infectious agents with antibiotics have provided mostly negative results, thereby challenging the validity of the infectious hypothesis of atherosclerosis...
  4. ncbi request reprint Childhood obesity and vascular phenotypes: a population study
    Marietta Charakida
    Vascular Physiology Unit, National Centre for Cardiovascular Disease Prevention and Outcomes, London, United Kingdom
    J Am Coll Cardiol 60:2643-50. 2012
    ..This study sought to assess the associations of childhood adiposity with vascular phenotype in pre-pubertal children...
  5. ncbi request reprint Inflammatory disorders and atherosclerosis: new therapeutic approaches
    Marietta Charakida
    Vascular Physiology Unit, Institute of Child Health, Great Ormond Street Hospital, London, WC1EH, UK
    Curr Pharm Des 17:4111-20. 2011
    ..Further longitudinal studies are required to assess the value of different therapeutic approaches on cardiovascular outcome of these patients...
  6. doi request reprint Vascular abnormalities, paraoxonase activity, and dysfunctional HDL in primary antiphospholipid syndrome
    Marietta Charakida
    Department of Vascular Physiology, The Institute of Child Health, University College London, 34 Great Ormond St, London WC1N 1EH, England
    JAMA 302:1210-7. 2009
    ..Accelerated atherosclerosis has been described in antiphospholipid syndrome, but the vascular abnormalities and the underlying mechanisms remain unclear...
  7. pmc Determinants of vascular phenotype in a large childhood population: the Avon Longitudinal Study of Parents and Children (ALSPAC)
    Ann E Donald
    Vascular Physiology Unit, Institute of Child Health, University College London, 30 Guilford Street, London WC1N 1EH, UK
    Eur Heart J 31:1502-10. 2010
    ..To assess the feasibility and reproducibility of non-invasive vascular assessment in a childhood population setting and identify the determinants of vascular phenotype in early life...
  8. pmc Adipose and height growth through childhood and blood pressure status in a large prospective cohort study
    Alexander Jones
    Vascular Physiology Unit, University College London Institute of Cardiovascular Science, London, UK
    Hypertension 59:919-25. 2012
    ....
  9. pmc Adiposity and cardiovascular risk factors in a large contemporary population of pre-pubertal children
    Emanuela Falaschetti
    Vascular Physiology Unit, Institute of Child Health, 30 Guilford Street, London WC1N 1EH, UK
    Eur Heart J 31:3063-72. 2010
    ..to examine the associations of several markers of adiposity and a wide range of cardiovascular risk factors and biomarkers in pre-pubertal children...
  10. doi request reprint Endothelial response to childhood infection: the role of mannose-binding lectin (MBL)
    Marietta Charakida
    Vascular Physiology Unit, Institute of Child Health, University College London, 34 Great Ormond Street, London, UK
    Atherosclerosis 208:217-21. 2010
    ..To assess the influence of mannose-binding lectin (MBL) genotype on endothelial function in the presence and absence of infection in childhood...
  11. ncbi request reprint Non-invasive assessment of endothelial function: which technique?
    Ann E Donald
    Institute of Child Health, University College London, London, United Kingdom
    J Am Coll Cardiol 48:1846-50. 2006
    ..The purpose of this study was to compare 3 non-invasive techniques for assessment of endothelial function in adults and children and evaluate their utility in acute inflammation...
  12. doi request reprint Methodological approaches to optimize reproducibility and power in clinical studies of flow-mediated dilation
    Ann E Donald
    Vascular Physiology Unit, UCL Institute of Child Health, London, United Kingdom
    J Am Coll Cardiol 51:1959-64. 2008
    ..Our aim was to determine reproducibility of the flow-mediated dilation (FMD) response profile, and discriminatory ability of the components...
  13. ncbi request reprint Early structural and functional changes of the vasculature in HIV-infected children: impact of disease and antiretroviral therapy
    Marietta Charakida
    Vascular Physiology Unit, Institute of Child Health, London, UK
    Circulation 112:103-9. 2005
    ..The purpose of this study was to determine the impact of HIV infection and antiretroviral therapy (ART) on markers of early vascular disease in children...
  14. doi request reprint Postconditioning protects against human endothelial ischaemia-reperfusion injury via subtype-specific KATP channel activation and is mimicked by inhibition of the mitochondrial permeability transition pore
    Michael I Okorie
    Centre for Clinical Pharmacology, University College London, The Rayne Institute, 5 University Street, London, UK
    Eur Heart J 32:1266-74. 2011
    ....
  15. doi request reprint The role of flow-mediated dilatation in the evaluation and development of antiatherosclerotic drugs
    Marietta Charakida
    Vascular Physiology Unit, Institute of Child Health, University College London, 30 Guilford Street, London, UK
    Curr Opin Lipidol 20:460-6. 2009
    ..Its value as a surrogate tool for development of antiatherosclerotic drugs and noninvasive assessment of cardiovascular risk is also discussed...
  16. pmc Body mass index and height from infancy to adulthood and carotid intima-media thickness at 60 to 64 years in the 1946 British Birth Cohort Study
    William Johnson
    From the MRC Unit for Lifelong Health and Ageing at UCL W J, D K, V T, R H and National Centre for Cardiovascular Prevention and Outcomes, Institute of Cardiovascular Science M C, J W, J E D, University College London, London, United Kingdom Population Health Research Centre, Division of Population Health Sciences and Education, St George s University of London, London, United Kingdom P W and International Centre for Circulatory Health, National Heart and Lung Institute, Faculty of Medicine, Imperial College London, London, United Kingdom A D H
    Arterioscler Thromb Vasc Biol 34:654-60. 2014
    ..Atherosclerosis begins early in life and obesity is a key determinant. We investigated the role of body mass index (BMI) and height from infancy to adulthood in presenting with high adulthood carotid intima-media thickness...
  17. ncbi request reprint Role of NADPH oxidase in endothelial ischemia/reperfusion injury in humans
    Stavros P Loukogeorgakis
    Institute of Child Health, University College London, UK
    Circulation 121:2310-6. 2010
    ..These patients have a molecular lesion in a subunit of NADPH oxidase that renders the enzyme inactive...
  18. doi request reprint Drug treatment of obesity in cardiovascular disease
    Marietta Charakida
    Vascular Physiology Unit, Institute of Child Health, London, UK
    Am J Cardiovasc Drugs 12:93-104. 2012
    ..This review comments on available anti-obesity pharmacologic regimens, their weight-loss benefit, and their impact on cardiovascular risk factors...
  19. doi request reprint The Year in Cardiology 2012: focus on cardiovascular disease prevention
    Marietta Charakida
    National Centre for Cardiovascular Prevention and Outcomes, Institute of Cardiovascular Science, University College London, UK
    Eur Heart J 34:314-7. 2013
    ..Finally, we provide new information on lifestyle and pharmacological advances which are likely to result in significant CV risk reduction...
  20. pmc Levels of circulating endothelial cells and colony-forming units are influenced by age and dyslipidemia
    Francesca I Fabbri-Arrigoni
    Department of Infection and Immunity, Institute of Child Health, University College London, London, UK
    Pediatr Res 72:299-304. 2012
    ..The balance between endothelial injury and repair in childhood is poorly understood. We examined this relationship in healthy children, in adults, and in children with familial hypercholesterolemia (FH)...
  21. doi request reprint Assessment of atherosclerosis: the role of flow-mediated dilatation
    Marietta Charakida
    Vascular Physiology Unit, Great Ormond Street Hospital for Children, NHS Trust, University College London, 30 Guilford Street, London WC1N 3EH, UK
    Eur Heart J 31:2854-61. 2010
    ....
  22. ncbi request reprint Endothelial dysfunction in childhood infection
    Marietta Charakida
    Vascular Physiology Unit, 30 Guilford St, London WC1N 1EH, United Kingdom
    Circulation 111:1660-5. 2005
    ..Although infection has been implicated in endothelial dysfunction and atherogenesis, the impact of acute common childhood infections on the vascular endothelium is unknown...
  23. ncbi request reprint Childhood origins of arterial disease
    Marietta Charakida
    Cardiac Unit, Institute of Child Health, University College London, 30 Guilford Street, London, UK
    Curr Opin Pediatr 19:538-45. 2007
    ..The value of noninvasive techniques that can assist in characterization of preclinical atherosclerotic changes as intermediate phenotypes is also discussed...