K R Chapman

Summary

Publications

  1. ncbi Salmeterol and fluticasone propionate (50/250 microg) administered via combination Diskus inhaler: as effective as when given via separate Diskus inhalers
    K R Chapman
    Toronto Hospital, Western Division, Toronto, Canada
    Can Respir J 6:45-51. 1999
  2. ncbi Gender bias in the diagnosis of COPD
    K R Chapman
    Division of Respiratory Medicine, Department of Medicine, University of Toronto, Toronto, Ontario, Canada
    Chest 119:1691-5. 2001
  3. ncbi Control of asthma in Canada: failure to achieve guideline targets
    K R Chapman
    University of Toronto, Toronto, Canada
    Can Respir J 8:35A-40A. 2001
  4. ncbi Defining the asthma phenotype for the purpose of genetic analysis
    S Kesten
    University of Toronto, Canada
    J Asthma 34:483-91. 1997
  5. ncbi Exhaled nitric oxide and bronchial reactivity during and after inhaled beclomethasone in mild asthma
    P E Silkoff
    Division of Respiratory Medicine, Faculty of Medicine, The University of Toronto, Canada
    J Asthma 35:473-9. 1998
  6. ncbi Exhaled nitric oxide in chronic obstructive pulmonary disease: relationship to pulmonary function
    K Ansarin
    Asthma Centre of the University Health Network, Toronto, Ontario, Canada
    Eur Respir J 17:934-8. 2001
  7. ncbi The patient level cost of asthma in adults in south central Ontario. Pharmacy Medication Monitoring Program Advisory Board
    W J Ungar
    Department of Health Administration and Division of Respirology, University of Toronto, Toronto, Canada
    Can Respir J 5:463-71. 1998
  8. ncbi Suboptimal asthma control: prevalence, detection and consequences in general practice
    K R Chapman
    University of Toronto, Canada
    Eur Respir J 31:320-5. 2008
  9. ncbi Respiratory rate during acute asthma
    S Kesten
    Division of Respiratory Medicine, Toronto Western Hospital, Canada
    Chest 97:58-62. 1990
  10. ncbi Inhaled beclomethasone dipropionate improves acoustic measures of voice in patients with asthma
    M S Balter
    Asthma Education Clinic, Mt Sinai Hospital, University of Toronto, Toronto, Canada
    Chest 120:1829-34. 2001

Detail Information

Publications24

  1. ncbi Salmeterol and fluticasone propionate (50/250 microg) administered via combination Diskus inhaler: as effective as when given via separate Diskus inhalers
    K R Chapman
    Toronto Hospital, Western Division, Toronto, Canada
    Can Respir J 6:45-51. 1999
    ..To compare the efficacy and safety of a new combination Diskus inhaler containing both salmeterol 50 mg and fluticasone propionate 250 mg (Seretide) with the two drugs delivered via separate Diskus inhalers...
  2. ncbi Gender bias in the diagnosis of COPD
    K R Chapman
    Division of Respiratory Medicine, Department of Medicine, University of Toronto, Toronto, Ontario, Canada
    Chest 119:1691-5. 2001
    ..There may also be underdiagnosis and misdiagnosis of COPD in both sexes because objective measures of lung function are underused...
  3. ncbi Control of asthma in Canada: failure to achieve guideline targets
    K R Chapman
    University of Toronto, Toronto, Canada
    Can Respir J 8:35A-40A. 2001
    ..To assess the degree of asthma control achieved by patients with asthma in Canada and to describe the impact of poor asthma control...
  4. ncbi Defining the asthma phenotype for the purpose of genetic analysis
    S Kesten
    University of Toronto, Canada
    J Asthma 34:483-91. 1997
    ....
  5. ncbi Exhaled nitric oxide and bronchial reactivity during and after inhaled beclomethasone in mild asthma
    P E Silkoff
    Division of Respiratory Medicine, Faculty of Medicine, The University of Toronto, Canada
    J Asthma 35:473-9. 1998
    ..3+/-46.1 at 1 week after withdrawal. ENO did not correlate with PC20 or FEV1. The changes in ENO and PC20 were inversely correlated (r2 = 0.325). ENO may be an index of airway inflammation and therapeutic response in bronchial asthma...
  6. ncbi Exhaled nitric oxide in chronic obstructive pulmonary disease: relationship to pulmonary function
    K Ansarin
    Asthma Centre of the University Health Network, Toronto, Ontario, Canada
    Eur Respir J 17:934-8. 2001
    ..Exhaled nitric oxide is increased in patients with chronic obstructive pulmonary disease, an increase that is influenced by structural abnormalities of tobacco-induced lung damage...
  7. ncbi The patient level cost of asthma in adults in south central Ontario. Pharmacy Medication Monitoring Program Advisory Board
    W J Ungar
    Department of Health Administration and Division of Respirology, University of Toronto, Toronto, Canada
    Can Respir J 5:463-71. 1998
    ..To assess the annual cost of asthma per adult patient from the perspectives of society, the Ontario Ministry of Health and the patient...
  8. ncbi Suboptimal asthma control: prevalence, detection and consequences in general practice
    K R Chapman
    University of Toronto, Canada
    Eur Respir J 31:320-5. 2008
    ..Lack of control can be recognised by physicians who are likely to consider appropriate changes to therapy. A lack of short-term symptom control of asthma is associated with excess healthcare utilisation...
  9. ncbi Respiratory rate during acute asthma
    S Kesten
    Division of Respiratory Medicine, Toronto Western Hospital, Canada
    Chest 97:58-62. 1990
    ..In the former setting, the respiratory rate is correlated with spirometric measures of airflow obstruction, but the weakness of the correlation does not allow the respiratory rate to be used as a substitute for spirometry...
  10. ncbi Inhaled beclomethasone dipropionate improves acoustic measures of voice in patients with asthma
    M S Balter
    Asthma Education Clinic, Mt Sinai Hospital, University of Toronto, Toronto, Canada
    Chest 120:1829-34. 2001
    ..Inhaled corticosteroids have the potential to produce upper-airway side effects such as hoarseness. As new compounds and delivery devices are developed and compared, it is difficult to quantify their adverse upper-airway effects...
  11. ncbi Exhaled nitric oxide and hydrogen peroxide in patients with chronic obstructive pulmonary disease: effects of inhaled beclomethasone
    I M Ferreira
    Asthma Centre, University of Toronto, Toronto Western Hospital, University Health Network, Toronto, Ontario, Canada
    Am J Respir Crit Care Med 164:1012-5. 2001
    ..50). We conclude that inhaled beclomethasone reduces ENO levels in stable nonsmoking patients with COPD, a finding compatible with an antiinflammatory mechanism of action...
  12. ncbi Changes in pulmonary function and cross-sectional area of trachea and bronchi in asthmatics following inhalation of procaterol hydrochloride and ipratropium bromide
    V Hoffstein
    Department of Medicine, St Michael s Hospital, Toronto, Canada
    Am J Respir Crit Care Med 149:81-5. 1994
    ..abstract truncated at 250 words)..
  13. ncbi Inhaler education for hospital-based pharmacists: how much is required?
    C A Jackevicius
    The Toronto Hospital and Faculty of Pharmacy, University of Toronto, Toronto, Canada
    Can Respir J 6:237-44. 1999
    ..To compare the effectiveness of a more intensive educational intervention with a less intensive intervention on the ability of hospital pharmacists to be prepared to educate patients regarding inhaled device technique...
  14. ncbi The impact of a nationally coordinated pharmacy-based asthma education intervention
    S A Diamond
    Pedipharm Consultants, Toronto, Ontario
    Can Respir J 8:261-5. 2001
    ..To assess the impact of a nationally coordinated pharmacy-based educational intervention on self-management behaviour and markers of asthma control in self-referred patients with asthma...
  15. ncbi Effectiveness and safety of salmeterol in nonspecialist practice settings
    K R Chapman
    University of Toronto, Toronto, Ontario, Canada
    Chest 119:714-9. 2001
    ..028). CONCLUSIONS: Salmeterol treatment is effective in subjects typically cared for in the primary-care setting and does not increase the frequency of severe exacerbations...
  16. ncbi Patient handling of a dry-powder inhaler in clinical practice
    S Epstein
    Asthma Centre, Toronto Western Hospital, University Health Network, Toronto, Ontario, Canada
    Chest 120:1480-4. 2001
    ..The most common handling flaw, suboptimal breath-holding, is not specific to this device and is of uncertain clinical significance...
  17. doi The clinical impact of single inhaler therapy in asthma
    K Czarnecka
    Asthma and Airway Centre, University Health Network, Toronto Western Hospital, Toronto, Ontario, Canada
    Clin Exp Allergy 42:1006-13. 2012
    ....
  18. ncbi Maintenance of asthma control by once-daily inhaled ciclesonide in adults with persistent asthma
    K R Chapman
    Toronto Western Hospital, University Health Network, Toronto, Ontario, Canada
    Allergy 60:330-7. 2005
    ..This 12-week, double-blind, randomized, parallel-group, placebo-controlled study evaluated the efficacy and safety of ciclesonide in adults with persistent asthma...
  19. ncbi Difficult asthma: consider all of the possibilities
    L C Cicutto
    Toronto Western Hospital, Toronto, Canada
    Can Respir J 7:415-8. 2000
    ..This led to a surgical resection of a mucoepidermoid carcinoma. This case highlights the need to consider all possibilities during the evaluation of patients with difficult asthma...
  20. ncbi Induced sputum: comparison of postinfectious cough with allergic asthma in children
    B Zimmerman
    Gage Occupational and Environmental Health Unit, St Michael s Hospital, and the Asthma Centre, Toronto Western Hospital, University of Toronto, Toronto, Ontario, Canada
    J Allergy Clin Immunol 105:495-9. 2000
    ..Cough persisting after a respiratory infection is common in children and is often managed as asthma. However, little is known about the pathophysiologic mechanisms of such cough and how it compares with asthma...
  21. ncbi Epidemiology and costs of chronic obstructive pulmonary disease
    K R Chapman
    Asthma and Airway Centre, Toronto University Health Network, Toronto Western Hospital, Room 7 451 New East Wing, 399 Bathurst Street, Toronto, Ontario M5T 2S8, Canada
    Eur Respir J 27:188-207. 2006
  22. pmc A 21-year-old man with systemic-onset juvenile rheumatoid arthritis, cough and progressive dyspnea
    A Leber
    Department of Medicine, University Health Network, University of Toronto, Toronto, Ontario, Canada
    Can Respir J 17:e42-4. 2010
    ..Multiple treatment regimens were attempted; however, definitive management was only achieved through double-lung transplantation...
  23. ncbi Corticosteroid therapy for patients with acute exacerbations of chronic obstructive pulmonary disease: a systematic review
    J M Singh
    Division of Internal Medicine, Room 4 154, St Michael s Hospital, 30 Bond St, Toronto, Ontario, Canada M5B 1W8
    Arch Intern Med 162:2527-36. 2002
    ..To determine whether systemic corticosteroids are of benefit to patients with acute exacerbations of chronic obstructive pulmonary disease (COPD)...
  24. ncbi The burden of COPD in Canada: results from the Confronting COPD survey
    K R Chapman
    University of Toronto, Ontario, Canada
    Respir Med 97:S23-31. 2003
    ..Early diagnosis and the application of available but underused interventions (e.g. smoking cessation, inhaled drug therapies and pulmonary rehabilitation) could reduce the morbidity and costs of COPD in this country...