Avinash Chander

Summary

Publications

  1. pmc Annexin A7 trafficking to alveolar type II cell surface: possible roles for protein insertion into membranes and lamellar body secretion
    Avinash Chander
    Department of Pediatrics, Stony Brook University Medical Center, Stony Brook, NY, USA
    Biochim Biophys Acta 1833:1244-55. 2013
  2. ncbi request reprint A ten-residue domain (Y11-A20) in the NH2-terminus modulates membrane association of annexin A7
    Avinash Chander
    Department of Pediatrics, Stony Brook University School of Medicine, Stony Brook, NY 11794 8111, USA
    Biochim Biophys Acta 1761:775-84. 2006
  3. ncbi request reprint Partial truncation of the NH2-terminus affects physical characteristics and membrane binding, aggregation, and fusion properties of annexin A7
    Devendra G Naidu
    Department of Pediatrics, Division of Neonatology, Stony Brook University School of Medicine, Health Sciences Center, T 11, Room 051, Stony Brook, NY 11794 8111, USA
    Biochim Biophys Acta 1734:152-68. 2005
  4. pmc A role for diacylglycerol in annexin A7-mediated fusion of lung lamellar bodies
    Avinash Chander
    Division of Neonatology and the Brady Laboratory, Department of Pediatrics, Stony Brook University Medical Center, Stony Brook, NY 11794, USA
    Biochim Biophys Acta 1771:1308-18. 2007
  5. pmc Annexin A7 and SNAP23 interactions in alveolar type II cells and in vitro: a role for Ca(2+) and PKC
    Tudevdagva Gerelsaikhan
    Department of Pediatrics, Stony Brook University Medical, Stony Brook, NY 11794, USA
    Biochim Biophys Acta 1823:1796-806. 2012
  6. pmc Secretagogues of lung surfactant increase annexin A7 localization with ABCA3 in alveolar type II cells
    Tudevdagva Gerelsaikhan
    Department of Pediatrics, Stony Brook University Medical Center, Stony Brook, NY 11794, USA
    Biochim Biophys Acta 1813:2017-25. 2011
  7. pmc Transient in utero disruption of cystic fibrosis transmembrane conductance regulator causes phenotypic changes in alveolar type II cells in adult rats
    Ashraf Gad
    The Brady Laboratory, Department of Pediatrics, Division of Neonatology, Stony Brook University Medical Center, Stony Brook, NY 11794, USA
    BMC Cell Biol 10:24. 2009
  8. ncbi request reprint Calcium ionophore and phorbol ester increase membrane binding of annexin a7 in alveolar type II cells
    Avinash Chander
    Department of Pediatrics, Division of Neonatology, State University of New York, Stony Brook, NY 11794 8111, USA
    Cell Calcium 33:11-7. 2003
  9. doi request reprint Simulated transport alters surfactant homeostasis and causes dose-dependent changes in respiratory function in neonatal Sprague-Dawley rats
    Shetal Shah
    Division of Neonatology, Department of Pediatrics, State University of New York at Stony Brook, Stony Brook, New York, NY, USA
    J Perinat Med 38:535-43. 2010
  10. pmc Small interfering peptide (siP) for in vivo examination of the developing lung interactonome
    J Craig Cohen
    The Brady Laboratory, Section of Neonatology, Department of Pediatrics, Stony Brook University, School of Medicine, Stony Brook, New York 11794, USA
    Dev Dyn 238:386-93. 2009

Collaborators

Detail Information

Publications10

  1. pmc Annexin A7 trafficking to alveolar type II cell surface: possible roles for protein insertion into membranes and lamellar body secretion
    Avinash Chander
    Department of Pediatrics, Stony Brook University Medical Center, Stony Brook, NY, USA
    Biochim Biophys Acta 1833:1244-55. 2013
    ..Together, our studies support in vivo association between surfactant secretion and cell surface A7 occurring by insertion into plasma membrane and by fusion of A7 containing lamellar bodies...
  2. ncbi request reprint A ten-residue domain (Y11-A20) in the NH2-terminus modulates membrane association of annexin A7
    Avinash Chander
    Department of Pediatrics, Stony Brook University School of Medicine, Stony Brook, NY 11794 8111, USA
    Biochim Biophys Acta 1761:775-84. 2006
    ..For binding and fusion of biological membranes, the 10-29-residue domain may be required although the annexin A7 properties are primarily modulated through the Y(11)-A(20) domain...
  3. ncbi request reprint Partial truncation of the NH2-terminus affects physical characteristics and membrane binding, aggregation, and fusion properties of annexin A7
    Devendra G Naidu
    Department of Pediatrics, Division of Neonatology, Stony Brook University School of Medicine, Health Sciences Center, T 11, Room 051, Stony Brook, NY 11794 8111, USA
    Biochim Biophys Acta 1734:152-68. 2005
    ..We speculate that interactions between the NH2- and COOH-termini are required for membrane binding, and aggregation and fusion properties of annexin A7...
  4. pmc A role for diacylglycerol in annexin A7-mediated fusion of lung lamellar bodies
    Avinash Chander
    Division of Neonatology and the Brady Laboratory, Department of Pediatrics, Stony Brook University Medical Center, Stony Brook, NY 11794, USA
    Biochim Biophys Acta 1771:1308-18. 2007
    ..Thus, increased diacylglycerol in lamellar bodies following cell stimulation with secretagogues may enhance membrane fusion activity of annexin A7...
  5. pmc Annexin A7 and SNAP23 interactions in alveolar type II cells and in vitro: a role for Ca(2+) and PKC
    Tudevdagva Gerelsaikhan
    Department of Pediatrics, Stony Brook University Medical, Stony Brook, NY 11794, USA
    Biochim Biophys Acta 1823:1796-806. 2012
    ....
  6. pmc Secretagogues of lung surfactant increase annexin A7 localization with ABCA3 in alveolar type II cells
    Tudevdagva Gerelsaikhan
    Department of Pediatrics, Stony Brook University Medical Center, Stony Brook, NY 11794, USA
    Biochim Biophys Acta 1813:2017-25. 2011
    ..We suggest that activation of protein kinase promotes phosphorylation and membrane-association of A7 presumably to facilitate membrane fusion during lung surfactant secretion...
  7. pmc Transient in utero disruption of cystic fibrosis transmembrane conductance regulator causes phenotypic changes in alveolar type II cells in adult rats
    Ashraf Gad
    The Brady Laboratory, Department of Pediatrics, Division of Neonatology, Stony Brook University Medical Center, Stony Brook, NY 11794, USA
    BMC Cell Biol 10:24. 2009
    ..In this study, we examined adult alveolar type II (ATII) cell phenotype after transient knock down of CFTR by adenovirus-directed in utero expression of ASCFTR in the fetal lung...
  8. ncbi request reprint Calcium ionophore and phorbol ester increase membrane binding of annexin a7 in alveolar type II cells
    Avinash Chander
    Department of Pediatrics, Division of Neonatology, State University of New York, Stony Brook, NY 11794 8111, USA
    Cell Calcium 33:11-7. 2003
    ..Collectively, our findings suggest that these two agents modify membrane proteins to regulate anx a7 binding, which may facilitate increased membrane fusion activity during stimulation of surfactant secretion...
  9. doi request reprint Simulated transport alters surfactant homeostasis and causes dose-dependent changes in respiratory function in neonatal Sprague-Dawley rats
    Shetal Shah
    Division of Neonatology, Department of Pediatrics, State University of New York at Stony Brook, Stony Brook, New York, NY, USA
    J Perinat Med 38:535-43. 2010
    ..In this study, we sought to determine the relationship between the duration of transport and respiratory performance in the rat model...
  10. pmc Small interfering peptide (siP) for in vivo examination of the developing lung interactonome
    J Craig Cohen
    The Brady Laboratory, Section of Neonatology, Department of Pediatrics, Stony Brook University, School of Medicine, Stony Brook, New York 11794, USA
    Dev Dyn 238:386-93. 2009
    ..Physiologically, it was shown that siPs that interfered with the NOX-CFTR-CK2 complex that we call an "interactonome" affected markers of stretch-induced lung organogenesis including Wnt/beta-catenin signaling...