Mark Y Chan

Summary

Publications

  1. doi request reprint Long-term mortality of patients undergoing cardiac catheterization for ST-elevation and non-ST-elevation myocardial infarction
    Mark Y Chan
    MBBS, MHS, National University Heart Center, 5 Lower Kent Ridge Road, Singapore, Singapore 119074
    Circulation 119:3110-7. 2009
  2. doi request reprint Catheter thrombosis and percutaneous coronary intervention: fundamental perspectives on blood, artificial surfaces and antithrombotic drugs
    Mark Y Chan
    National University Heart Centre, Singapore, Singapore
    J Thromb Thrombolysis 28:366-80. 2009
  3. ncbi request reprint Reperfusion strategy and mortality in ST-elevation myocardial infarction among patients with and without impaired renal function
    Mark Y Chan
    National University Heart Centre, Singapore, Singapore
    Ann Acad Med Singapore 39:179-84. 2010
  4. doi request reprint Angiographic and platelet reactivity outcomes with prasugrel 60 mg pretreatment and clopidogrel 600 mg pretreatment in primary percutaneous coronary intervention
    Yiding Li
    Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore
    J Thromb Thrombolysis 34:499-505. 2012
  5. doi request reprint Procedure-related myonecrosis after bare and drug-eluting stent implantation
    Chi Hang Lee
    Cardiac Department, National University Heart Center, 5 Lower Kent Ridge Road, Singapore
    Asian Cardiovasc Thorac Ann 18:272-8. 2010
  6. doi request reprint Effectiveness and safety of the genous endothelial progenitor cell-capture stent in acute ST-elevation myocardial infarction
    Adrian F Low
    National University Heart Centre, Singapore
    Am J Cardiol 108:202-5. 2011
  7. doi request reprint Recalibration of the Global Registry of Acute Coronary Events risk score in a multiethnic Asian population
    Mark Y Chan
    National University Heart Centre, Singapore, Singapore
    Am Heart J 162:291-9. 2011
  8. doi request reprint CYP2C19 and PON1 polymorphisms regulating clopidogrel bioactivation in Chinese, Malay and Indian subjects
    Mark Y Chan
    National University Heart Centre, 1E Kent Ridge Road, Singapore 119228, Singapore
    Pharmacogenomics 13:533-42. 2012
  9. doi request reprint Adiponectin profile in Asian patients undergoing coronary revascularization and its association with plaque vulnerability: IDEAS-ADIPO study
    Chi Hang Lee
    Department of Medicine, National University of Singapore, Singapore
    Obesity (Silver Spring) 20:2451-7. 2012
  10. doi request reprint Renal function and anaemia in acute myocardial infarction
    Leonardo Pinto de Carvalho
    National University Heart Centre, Singapore
    Int J Cardiol 168:1397-401. 2013

Collaborators

Detail Information

Publications18

  1. doi request reprint Long-term mortality of patients undergoing cardiac catheterization for ST-elevation and non-ST-elevation myocardial infarction
    Mark Y Chan
    MBBS, MHS, National University Heart Center, 5 Lower Kent Ridge Road, Singapore, Singapore 119074
    Circulation 119:3110-7. 2009
    ..There are limited contemporary data comparing long-term outcomes after cardiac catheterization for ST-segment elevation myocardial infarction (STEMI) and non-STEMI (NSTEMI)...
  2. doi request reprint Catheter thrombosis and percutaneous coronary intervention: fundamental perspectives on blood, artificial surfaces and antithrombotic drugs
    Mark Y Chan
    National University Heart Centre, Singapore, Singapore
    J Thromb Thrombolysis 28:366-80. 2009
    ..We also propose a clinical classification for the diagnosis and investigation of catheter thrombosis in clinical trials of anticoagulant therapy and PCI...
  3. ncbi request reprint Reperfusion strategy and mortality in ST-elevation myocardial infarction among patients with and without impaired renal function
    Mark Y Chan
    National University Heart Centre, Singapore, Singapore
    Ann Acad Med Singapore 39:179-84. 2010
    ..Whether this benefit extends to patients with impaired renal function is uncertain...
  4. doi request reprint Angiographic and platelet reactivity outcomes with prasugrel 60 mg pretreatment and clopidogrel 600 mg pretreatment in primary percutaneous coronary intervention
    Yiding Li
    Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore
    J Thromb Thrombolysis 34:499-505. 2012
    ..The very high frequency of high on-clopidogrel platelet reactivity with 600 mg of clopidogrel in this Asian STEMI cohort deserves further study...
  5. doi request reprint Procedure-related myonecrosis after bare and drug-eluting stent implantation
    Chi Hang Lee
    Cardiac Department, National University Heart Center, 5 Lower Kent Ridge Road, Singapore
    Asian Cardiovasc Thorac Ann 18:272-8. 2010
    ..In this study, bare metal stents and the 4 drug-eluting stents were associated with similar low incidences of myonecrosis, myocardial infarction, and large myocardial infarction...
  6. doi request reprint Effectiveness and safety of the genous endothelial progenitor cell-capture stent in acute ST-elevation myocardial infarction
    Adrian F Low
    National University Heart Centre, Singapore
    Am J Cardiol 108:202-5. 2011
    ..In conclusion, implantation of the EPC-capture stent during primary angioplasty is associated with a favorable late clinical outcome but with higher than anticipated angiographic late loss...
  7. doi request reprint Recalibration of the Global Registry of Acute Coronary Events risk score in a multiethnic Asian population
    Mark Y Chan
    National University Heart Centre, Singapore, Singapore
    Am Heart J 162:291-9. 2011
    ..Acute myocardial infarction (AMI) is a leading cause of mortality in Asia. However, quantitative risk scores to predict mortality after AMI were developed without the participation of Asian countries...
  8. doi request reprint CYP2C19 and PON1 polymorphisms regulating clopidogrel bioactivation in Chinese, Malay and Indian subjects
    Mark Y Chan
    National University Heart Centre, 1E Kent Ridge Road, Singapore 119228, Singapore
    Pharmacogenomics 13:533-42. 2012
    ....
  9. doi request reprint Adiponectin profile in Asian patients undergoing coronary revascularization and its association with plaque vulnerability: IDEAS-ADIPO study
    Chi Hang Lee
    Department of Medicine, National University of Singapore, Singapore
    Obesity (Silver Spring) 20:2451-7. 2012
    ..Increased serum adiponectin levels were independently associated with increased culprit lesion NC burden, suggesting a role for adiponectin in modulating coronary plaque vulnerability...
  10. doi request reprint Renal function and anaemia in acute myocardial infarction
    Leonardo Pinto de Carvalho
    National University Heart Centre, Singapore
    Int J Cardiol 168:1397-401. 2013
    ..While both conditions are known independent risk factors for increased mortality, their interaction as risk factors for increased mortality in AMI is unclear...
  11. doi request reprint Immigrant status and disparities in health care delivery in patients with myocardial infarction
    Chi Hang Lee
    Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
    Int J Cardiol 166:696-701. 2013
    ..We investigated the differences in socioeconomic status and quality health care between Singapore-born citizens and immigrants presenting with ST-segment elevation myocardial infarction (STEMI)...
  12. doi request reprint Plasma proteomics of patients with non-valvular atrial fibrillation on chronic anti-coagulation with warfarin or a direct factor Xa inhibitor
    Mark Y Chan
    National University Heart Centre, Singapore
    Thromb Haemost 108:1180-91. 2012
    ....
  13. pmc Excessive Daytime Sleepiness is Associated with Longer Culprit Lesion and Adverse Outcomes in Patients with Coronary Artery Disease
    Chi Hang Lee
    Department of Cardiology, National University Heart Centre, Singapore Yong Loo Lin School of Medicine, National University of Singapore, National University Health System, Singapore
    J Clin Sleep Med 9:1267-72. 2013
    ..We assessed whether excessive daytime sleepiness was associated with coronary plaque phenotype and subsequent adverse cardiovascular events...
  14. doi request reprint Patterns of discharge antiplatelet therapy and late outcomes among 8,582 patients with bleeding during acute coronary syndrome: a pooled analysis from PURSUIT, PARAGON-A, PARAGON-B, and SYNERGY
    Mark Y Chan
    National University Heart Centre, Singapore, Singapore
    Am Heart J 160:1056-64, 1064.e2. 2010
    ..Patients with bleeding are often discharged without antiplatelet therapy (AT). The association between discharge AT use and late ischemic outcomes among ACS patients with bleeding is uncertain...
  15. doi request reprint The influence of timing of polysomnography on diagnosis of obstructive sleep apnea in patients presenting with acute myocardial infarction and stable coronary artery disease
    Ting Ting Low
    Department of Cardiology, National University Heart Centre, Singapore
    Sleep Med 14:985-90. 2013
    ..We aimed to determine if timing of polysomnography (PSG) influences the diagnosis of obstructive sleep apnea (OSA) in acute myocardial infarction (AMI) or stable coronary artery disease (CAD)...
  16. doi request reprint Trends in clinical trials of non-ST-segment elevation acute coronary syndromes over 15 years
    Mark Y Chan
    National University Heart Center, Singapore, Singapore
    Int J Cardiol 167:548-54. 2013
    ..We quantified changes in baseline risk, treatment, and outcomes of patients with non-ST-segment elevation acute coronary syndromes (NSTE ACS) randomized in 9 phase 3 clinical trials of antithrombotic therapy over 15 years...
  17. ncbi request reprint Clinical characteristics and prognostic importance of mild-to-moderate noninfarct-related coronary artery disease in patients with first ST-elevation myocardial infarction
    Wern Miin Soo
    Cardiac Department, National University Heart Centre, NUHS Tower Block, Level 9, 1E Kent Ridge Road, Singapore 119228, Singapore
    Coron Artery Dis 22:55-8. 2011
    ..However, there are limited data on patients with angiographically mild-to-moderate (< 70%) noninfarct-related artery (IRA) stenoses...
  18. ncbi request reprint Pretreatment with intracoronary adenosine reduces the incidence of myonecrosis after non-urgent percutaneous coronary intervention: a prospective randomized study
    Chi Hang Lee
    Cardiac Department, National University Hospital, 5 Lower Kent Ridge Road, Singapore 119074
    Eur Heart J 28:19-25. 2007
    ..We sought to investigate the effect of adenosine pretreatment on the incidence of myonecrosis after non-urgent percutaneous coronary intervention (PCI)...