Long-term mortality of patients undergoing cardiac catheterization for ST-elevation and non-ST-elevation myocardial infarctionMark Y Chan
MBBS, MHS, National University Heart Center, 5 Lower Kent Ridge Road, Singapore, Singapore 119074
Circulation 119:3110-7. 2009
..There are limited contemporary data comparing long-term outcomes after cardiac catheterization for ST-segment elevation myocardial infarction (STEMI) and non-STEMI (NSTEMI)...
- Catheter thrombosis and percutaneous coronary intervention: fundamental perspectives on blood, artificial surfaces and antithrombotic drugs
Mark Y Chan
National University Heart Centre, Singapore, Singapore
J Thromb Thrombolysis 28:366-80. 2009
..We also propose a clinical classification for the diagnosis and investigation of catheter thrombosis in clinical trials of anticoagulant therapy and PCI...
Reperfusion strategy and mortality in ST-elevation myocardial infarction among patients with and without impaired renal functionMark Y Chan
National University Heart Centre, Singapore, Singapore
Ann Acad Med Singapore 39:179-84. 2010
..Whether this benefit extends to patients with impaired renal function is uncertain...
- Angiographic and platelet reactivity outcomes with prasugrel 60 mg pretreatment and clopidogrel 600 mg pretreatment in primary percutaneous coronary intervention
Yiding Li
Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore
J Thromb Thrombolysis 34:499-505. 2012
..The very high frequency of high on-clopidogrel platelet reactivity with 600 mg of clopidogrel in this Asian STEMI cohort deserves further study...
- Recalibration of the Global Registry of Acute Coronary Events risk score in a multiethnic Asian population
Mark Y Chan
National University Heart Centre, Singapore, Singapore
Am Heart J 162:291-9. 2011
..Acute myocardial infarction (AMI) is a leading cause of mortality in Asia. However, quantitative risk scores to predict mortality after AMI were developed without the participation of Asian countries...
- Adiponectin profile in Asian patients undergoing coronary revascularization and its association with plaque vulnerability: IDEAS-ADIPO study
Chi Hang Lee
Department of Medicine, National University of Singapore, Singapore
Obesity (Silver Spring) 20:2451-7. 2012
..Increased serum adiponectin levels were independently associated with increased culprit lesion NC burden, suggesting a role for adiponectin in modulating coronary plaque vulnerability...
- Effectiveness and safety of the genous endothelial progenitor cell-capture stent in acute ST-elevation myocardial infarction
Adrian F Low
National University Heart Centre, Singapore
Am J Cardiol 108:202-5. 2011
..In conclusion, implantation of the EPC-capture stent during primary angioplasty is associated with a favorable late clinical outcome but with higher than anticipated angiographic late loss...
- Plasma proteomics of patients with non-valvular atrial fibrillation on chronic anti-coagulation with warfarin or a direct factor Xa inhibitor
Mark Y Chan
National University Heart Centre, Singapore
Thromb Haemost 108:1180-91. 2012
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- CYP2C19 and PON1 polymorphisms regulating clopidogrel bioactivation in Chinese, Malay and Indian subjects
Mark Y Chan
National University Heart Centre, 1E Kent Ridge Road, Singapore 119228, Singapore
Pharmacogenomics 13:533-42. 2012
..All three polymorphisms should preferably be genotyped in Malays...
- Procedure-related myonecrosis after bare and drug-eluting stent implantation
Chi Hang Lee
Cardiac Department, National University Heart Center, 5 Lower Kent Ridge Road, Singapore
Asian Cardiovasc Thorac Ann 18:272-8. 2010
..In this study, bare metal stents and the 4 drug-eluting stents were associated with similar low incidences of myonecrosis, myocardial infarction, and large myocardial infarction...
- Clinical characteristics and prognostic importance of mild-to-moderate noninfarct-related coronary artery disease in patients with first ST-elevation myocardial infarction
Wern Miin Soo
Cardiac Department, National University Heart Centre, NUHS Tower Block, Level 9, 1E Kent Ridge Road, Singapore 119228, Singapore
Coron Artery Dis 22:55-8. 2011
..However, there are limited data on patients with angiographically mild-to-moderate (< 70%) noninfarct-related artery (IRA) stenoses...
- Patterns of discharge antiplatelet therapy and late outcomes among 8,582 patients with bleeding during acute coronary syndrome: a pooled analysis from PURSUIT, PARAGON-A, PARAGON-B, and SYNERGY
Mark Y Chan
National University Heart Centre, Singapore, Singapore
Am Heart J 160:1056-64, 1064.e2. 2010
..Patients with bleeding are often discharged without antiplatelet therapy (AT). The association between discharge AT use and late ischemic outcomes among ACS patients with bleeding is uncertain...
