Sajal Chakraborti

Summary

Publications

  1. ncbi request reprint Role of Ca2+-dependent metalloprotease-2 in stimulating Ca2+ ATPase activity under peroxynitrite treatment in bovine pulmonary artery smooth muscle membrane
    Tapati Chakraborti
    Department of Biochemistry and Biophysics, University of Kalyani, West Bengal, India
    IUBMB Life 53:167-73. 2002
  2. ncbi request reprint Regulation of matrix metalloproteinases: an overview
    Sajal Chakraborti
    Department of Biochemistry and Biophysics, University of Kalyani, Kalyani, West Bengal, India
    Mol Cell Biochem 253:269-85. 2003
  3. ncbi request reprint Protective role of magnesium in cardiovascular diseases: a review
    Sajal Chakraborti
    Department of Biochemistry and Biophysics, University of Kalyani, Kalyani, West Bengal, India
    Mol Cell Biochem 238:163-79. 2002
  4. ncbi request reprint Phospholipase A(2) isoforms: a perspective
    Sajal Chakraborti
    Department of Biochemistry and Biophysics, University of Kalyani, Kalyani 741235, West Bengal, India
    Cell Signal 15:637-65. 2003
  5. ncbi request reprint Identification, purification and partial characterization of tissue inhibitor of matrix metalloproteinase-2 in bovine pulmonary artery smooth muscle
    Malay Mandal
    Department of Biochemistry and Biophysics, University of Kalyani, Kalyani, West Bengal, India
    Mol Cell Biochem 254:275-87. 2003
  6. ncbi request reprint Role of MMP-2 in inhibiting Na+ dependent Ca2+ uptake by H2O2 in microsomes isolated from pulmonary smooth muscle
    Amritlal Mandal
    Department of Biochemistry and Biophysics, University of Kalyani, Kalyani, West Bengal, India
    Mol Cell Biochem 270:79-87. 2005
  7. ncbi request reprint Isolation of MMP-2 from MMP-2/TIMP-2 complex: characterization of the complex and the free enzyme in pulmonary vascular smooth muscle plasma membrane
    Sudip Das
    Department of Biochemistry and Biophysics, University of Kalyani, Kalyani 741235, West Bengal, India
    Biochim Biophys Acta 1674:158-74. 2004
  8. ncbi request reprint Oxidant-mediated activation of cytosolic phospholipase a(2) in pulmonary endothelium: role of protein kinase C alpha and a pertussis toxin-sensitive protein
    Sajal Chakraborti
    Department of Biochemistry and Biophysics, University of Kalyani, Kalyani, West Bengal, India
    Endothelium 12:121-31. 2005
  9. doi request reprint Calcium-dependent cleavage of the Na(+)/Ca(2+) exchanger by m-calpain in isolated endoplasmic reticulum
    Krishna Samanta
    Department of Biochemistry and Biophysics, University of Kalyani, Kalyani 741235, West Bengal, India
    J Biochem 147:225-35. 2010
  10. doi request reprint mu-Calpain mediated cleavage of the Na+/Ca2+ exchanger in isolated mitochondria under A23187 induced Ca2+ stimulation
    Pulak Kar
    Department of Biochemistry and Biophysics, University of Kalyani, Kalyani, West Bengal, India
    Arch Biochem Biophys 482:66-76. 2009

Collaborators

  • Alok K Banerjee
  • Tapati Chakraborti
  • Pulak Kar
  • Sudip Das
  • Amritlal Mandal
  • Krishna Samanta
  • Kuntal Dey
  • Soumitra Roy
  • Biswarup Ghosh
  • Malay Mandal
  • Animesh Chowdhury
  • Soni Shaikh
  • Rajdeep Choudhury
  • Malay Mandai
  • Sayed Modinur Rahaman
  • Amar Nath Ghosh
  • Amarnath Ghosh

Detail Information

Publications43

  1. ncbi request reprint Role of Ca2+-dependent metalloprotease-2 in stimulating Ca2+ ATPase activity under peroxynitrite treatment in bovine pulmonary artery smooth muscle membrane
    Tapati Chakraborti
    Department of Biochemistry and Biophysics, University of Kalyani, West Bengal, India
    IUBMB Life 53:167-73. 2002
    ....
  2. ncbi request reprint Regulation of matrix metalloproteinases: an overview
    Sajal Chakraborti
    Department of Biochemistry and Biophysics, University of Kalyani, Kalyani, West Bengal, India
    Mol Cell Biochem 253:269-85. 2003
    ....
  3. ncbi request reprint Protective role of magnesium in cardiovascular diseases: a review
    Sajal Chakraborti
    Department of Biochemistry and Biophysics, University of Kalyani, Kalyani, West Bengal, India
    Mol Cell Biochem 238:163-79. 2002
    ..Further research are needed for the incorporation of these findings toward the development of novel myocardial protective role of Mg2+ to reduce morbidity and mortality of patients suffering from a variety of cardiac diseases...
  4. ncbi request reprint Phospholipase A(2) isoforms: a perspective
    Sajal Chakraborti
    Department of Biochemistry and Biophysics, University of Kalyani, Kalyani 741235, West Bengal, India
    Cell Signal 15:637-65. 2003
    ..Furthermore, to date, there is limited information available regarding the regulation of iPLA(2) or sPLA(2) by these pathways...
  5. ncbi request reprint Identification, purification and partial characterization of tissue inhibitor of matrix metalloproteinase-2 in bovine pulmonary artery smooth muscle
    Malay Mandal
    Department of Biochemistry and Biophysics, University of Kalyani, Kalyani, West Bengal, India
    Mol Cell Biochem 254:275-87. 2003
    ..Treatment of the inhibitor with hydrogen peroxide, superoxide generating system (hypoxanthine plus xanthine oxidase) and peroxynitrite inactivated the inhibitor...
  6. ncbi request reprint Role of MMP-2 in inhibiting Na+ dependent Ca2+ uptake by H2O2 in microsomes isolated from pulmonary smooth muscle
    Amritlal Mandal
    Department of Biochemistry and Biophysics, University of Kalyani, Kalyani, West Bengal, India
    Mol Cell Biochem 270:79-87. 2005
    ..Thus, one of the mechanisms by which H2O2 activates MMP-2 could be due to inactivation of TIMP-2 by the oxidant. The resulting activation of MMP-2 subsequently inhibits Na+ dependent Ca2+ uptake in the microsomes...
  7. ncbi request reprint Isolation of MMP-2 from MMP-2/TIMP-2 complex: characterization of the complex and the free enzyme in pulmonary vascular smooth muscle plasma membrane
    Sudip Das
    Department of Biochemistry and Biophysics, University of Kalyani, Kalyani 741235, West Bengal, India
    Biochim Biophys Acta 1674:158-74. 2004
    ..We have also presented additional data indicating that the isolated preparation of 72-kDa gelatinase exhibited properties that are identical with MMP-2 obtained from different sources...
  8. ncbi request reprint Oxidant-mediated activation of cytosolic phospholipase a(2) in pulmonary endothelium: role of protein kinase C alpha and a pertussis toxin-sensitive protein
    Sajal Chakraborti
    Department of Biochemistry and Biophysics, University of Kalyani, Kalyani, West Bengal, India
    Endothelium 12:121-31. 2005
    ....
  9. doi request reprint Calcium-dependent cleavage of the Na(+)/Ca(2+) exchanger by m-calpain in isolated endoplasmic reticulum
    Krishna Samanta
    Department of Biochemistry and Biophysics, University of Kalyani, Kalyani 741235, West Bengal, India
    J Biochem 147:225-35. 2010
    ..Cleavage of NCX1 by m-calpain in the ER may be interpreted as the main cause of intracellular Ca(2+) overload in the smooth muscle, which could be important for the manifestation of pulmonary hypertension...
  10. doi request reprint mu-Calpain mediated cleavage of the Na+/Ca2+ exchanger in isolated mitochondria under A23187 induced Ca2+ stimulation
    Pulak Kar
    Department of Biochemistry and Biophysics, University of Kalyani, Kalyani, West Bengal, India
    Arch Biochem Biophys 482:66-76. 2009
    ..This cleavage of NCX may be interpreted as the main cause of Ca(2+) overload and could lay a key role in the activation of apoptotic process in pulmonary smooth muscle...
  11. ncbi request reprint Role of MMP-2 in PKCdelta-mediated inhibition of Na+ dependent Ca2+ uptake in microsomes of pulmonary smooth muscle: involvement of a pertussis toxin sensitive protein
    Sajal Chakraborti
    Department of Biochemistry and Biophysics, University of Kalyani, Kalyani, 741235, West Bengal, India
    Mol Cell Biochem 280:107-17. 2005
    ....
  12. doi request reprint Role of PKC-ζ in NADPH oxidase-PKCα-Giα axis dependent inhibition of β-adrenergic response by U46619 in pulmonary artery smooth muscle cells
    Sajal Chakraborti
    Department of Biochemistry and Biophysics, University of Kalyani, Nadia 741235, West Bengal, India Electronic address
    Arch Biochem Biophys 540:133-44. 2013
    ..Taken together, we suggest involvement of PKC-ζ in U46619 caused attenuation of isoproterenol stimulated β-adrenergic response, which is regulated by NADPH oxidase-PKCα-Giα axis in pulmonary artery smooth muscle cells...
  13. doi request reprint Role of PKCα-p(38)MAPK-G(i)α axis in NADPH oxidase derived O(2)(·-)-mediated activation of cPLA(2) under U46619 stimulation in pulmonary artery smooth muscle cells
    Sajal Chakraborti
    Department of Biochemistry and Biophysics, University of Kalyani, Kalyani 741235, West Bengal, India
    Arch Biochem Biophys 523:169-80. 2012
    ..The activated PKC-α then phosphorylates p(38)MAPK and that subsequently caused G(i)α phosphorylation leading to stimulation of cPLA(2) activity in the cell membrane...
  14. doi request reprint Identification, purification and partial characterization of a 70kDa inhibitor protein of Na(+)/K(+)-ATPase from cytosol of pulmonary artery smooth muscle
    Kuntal Dey
    Department of Biochemistry and Biophysics, University of Kalyani, Kalyani 741235, West Bengal, India
    Life Sci 86:473-81. 2010
    ..We sought to identify, purify and partially characterize a protein inhibitor of Na(+)/K(+)-ATPase in cytosol of pulmonary artery smooth muscle...
  15. doi request reprint m-Calpain-mediated cleavage of Na+/Ca2+ exchanger-1 in caveolae vesicles isolated from pulmonary artery smooth muscle
    Soni Shaikh
    Department of Biochemistry and Biophysics, University of Kalyani, Kalyani, 741235 West Bengal, India
    Mol Cell Biochem 341:167-80. 2010
    ....
  16. doi request reprint Role of protein kinase C in phospholemman mediated regulation of α₂β₁ isozyme of Na⁺/K⁺-ATPase in caveolae of pulmonary artery smooth muscle cells
    Kuntal Dey
    Department of Biochemistry and Biophysics, University of Kalyani, Kalyani 741235, West Bengal, India
    Biochimie 94:991-1000. 2012
    ....
  17. doi request reprint Role of protein kinase C in NADPH oxidase derived O2*(-)-mediated regulation of KV-LVOCC axis under U46619 induced increase in [Ca2+]i in pulmonary smooth muscle cells
    Sajal Chakraborti
    Department of Biochemistry and Biophysics, University of Kalyani, Kalyani 741235, West Bengal, India
    Arch Biochem Biophys 487:123-30. 2009
    ..b(558) of NADPH oxidase in the membrane. Overall, PKC plays an important role in NADPH oxidase derived O(2)(-)-mediated regulation of K(V)-LVOCC axis leading to an increase in [Ca(2+)](i) by U46619 in the cells...
  18. doi request reprint Ca2+ influx mechanisms in caveolae vesicles of pulmonary smooth muscle plasma membrane under inhibition of alpha2beta1 isozyme of Na+/K+-ATPase by ouabain
    Biswarup Ghosh
    Department of Biochemistry and Biophysics, University of Kalyani, Kalyani 741235, West Bengal, India
    Life Sci 84:139-48. 2009
    ..We sought to determine the mechanisms of an increase in Ca(2+) level in caveolae vesicles in pulmonary smooth muscle plasma membrane during Na(+)/K(+)-ATPase inhibition by ouabain...
  19. ncbi request reprint Inhibition of Na+/Ca2+ exchanger by peroxynitrite in microsomes of pulmonary smooth muscle: role of matrix metalloproteinase-2
    Sajal Chakraborti
    Department of Biochemistry and Biophysics, University of Kalyani, Kalyani 741235, West Bengal, India
    Biochim Biophys Acta 1671:70-8. 2004
    ....
  20. doi request reprint Characteristic properties of endoplasmic reticulum membrane m-calpain, calpastatin and lumen m-calpain: a comparative study between membrane and lumen m-calpains
    Krishna Samanta
    Department of Biochemistry and Biophysics, University of Kalyani, Kalyani 741235, West Bengal, India
    J Biochem 147:765-79. 2010
    ..6 and 4.7, respectively) and IC(50) (0.52 and 0.8 nM, respectively) values of 110 and 70 kDa calpastatins. For first time, we have determined the characteristic properties, regulation and functional activity of LCp in the ER lumen...
  21. ncbi request reprint Proteolytic activation of protein kinase Calpha by peroxynitrite in stimulating cytosolic phospholipase A2 in pulmonary endothelium: involvement of a pertussis toxin sensitive protein
    Tapati Chakraborti
    Department of Biochemistry and Biophysics, University of Kalyani, Kalyani 741235, West Bengal, India
    Biochemistry 44:5246-57. 2005
    ....
  22. doi request reprint Role of PKC-α in NF-κB-MT1-MMP-mediated activation of proMMP-2 by TNF-α in pulmonary artery smooth muscle cells
    Soumitra Roy
    Department of Biochemistry and Biophysics, University of Kalyani, Kalyani 741235, West Bengal, India
    J Biochem 153:289-302. 2013
    ....
  23. doi request reprint Solubilization, purification, and reconstitution of alpha 2 beta 1 isozyme of Na+/K+ -ATPase from caveolae of pulmonary smooth muscle plasma membrane: comparative studies with DHPC, C12E8, and Triton X-100
    Biswarup Ghosh
    Department of Biochemistry and Biophysics, University of Kalyani, Kalyani, West Bengal, 741235, India
    Mol Cell Biochem 323:169-84. 2009
    ..Circular dichroism analysis suggests that the DHPC-purified alpha(2)beta(1) isozyme of Na(+)/K(+)-ATPase possessed more organized secondary structure compared to the C(12)E(8)- and Triton X-100-purified isozyme...
  24. ncbi request reprint Role of membrane-associated Ca+ dependent matrix metalloprotease-2 in the oxidant activation of Ca2+Atpase by tertiary butylhydroperoxide
    Sudip Das
    Department of Biochemistry and Biophysics, University of Kalyani, West Bengal, India
    Mol Cell Biochem 237:85-93. 2002
    ..Pretreatment with TIMP-2 prevents the increase in Ca2+ATPase activity elicited by the low doses of MMP-2 and/or t-buOOH...
  25. doi request reprint Role of PKCα-p38 MAPK-Giα axis in peroxynitrite-mediated inhibition of β-adrenergic response in pulmonary artery smooth muscle cells
    Sajal Chakraborti
    Department of Biochemistry and Biophysics, University of Kalyani, Kalyani 741235, West Bengal, India
    Cell Signal 25:512-26. 2013
    ....
  26. doi request reprint Role of TGF-β1 and TNF-α in IL-1β mediated activation of proMMP-9 in pulmonary artery smooth muscle cells: involvement of an aprotinin sensitive protease
    Soumitra Roy
    Department of Biochemistry and Biophysics, University of Kalyani, West Bengal, India
    Arch Biochem Biophys 513:61-9. 2011
    ..Thus, IL-1β induced stimulation of the two progelatinases occurs via different mechanisms...
  27. ncbi request reprint Matrix metalloproteinase-2-mediated inhibition of Na+-dependent Ca+ uptake by superoxide radicals (O2*-) in microsomes of pulmonary smooth muscle
    Amritlal Mandal
    Department of Biochemistry and Biophysics, University of Kalyani, Kalyani 741235, West Bengal, India
    IUBMB Life 56:267-76. 2004
    ....
  28. ncbi request reprint Identification of calpastatin and mu-calpain and studies of their association in pulmonary smooth muscle mitochondria
    Pulak Kar
    Department of Biochemistry and Biophysics, University of Kalyani, Kalyani 741235, West Bengal, India
    Arch Biochem Biophys 466:290-9. 2007
    ....
  29. ncbi request reprint Matrix metalloprotease 2-mediated activation of Ca(2+)-ATPase by superoxide radical (O2*-) in plasma membrane of bovine pulmonary vascular smooth muscle
    Malay Mandai
    Department of Biochemistry and Biophysics, University of Kalyani, Kalyani 741 235, West Bengal, India
    Indian J Biochem Biophys 39:390-6. 2002
    ..Adding pure bovine MMP-2 to the smooth muscle membrane suspension causes an increase in Ca(2+)-ATPase activity, but the pretreatment with TIMP-2 inhibits the increase in the enzyme activity...
  30. ncbi request reprint Identification, purification and partial characterization of tissue inhibitor of matrix metalloproteinase-1 (TIMP-1) in bovine pulmonary artery smooth muscle
    Malay Mandal
    Department of Biochemistry and Biophysics, University of Kalyani, Kalyani, West Bengal, India
    Mol Cell Biochem 254:145-55. 2003
    ..It was also found to be inactive against the serine proteases trypsin and plasmin. The inhibitor was heat and acid resistant and it had the sensitivity to trypsin degradation and reduction-alkylation...
  31. ncbi request reprint Submitochondrial localization of associated mu-calpain and calpastatin
    Pulak Kar
    Department of Biochemistry and Biophysics, University of Kalyani, Kalyani 741235, West Bengal, India
    Arch Biochem Biophys 470:176-86. 2008
    ....
  32. ncbi request reprint Identification, purification and characterization of matrix metalloproteinase-2 in bovine pulmonary artery smooth muscle plasma membrane
    Sudip Das
    Department of Biochemistry and Biophysics, University of Kalyani, Kalyani, West Bengal, India
    Mol Cell Biochem 258:73-89. 2004
    ..Additionally, the purified MMP-2 degrades Dnp-Pro-Gln-Gly-Ile-Ala-Gly-Gln-D-Arg-OH (dinitrophenyl labelled peptide), a well known synthetic substrate for the MMP-2...
  33. ncbi request reprint Role of an aprotinin-sensitive protease in protein kinase Calpha-mediated activation of cytosolic phospholipase A2 by calcium ionophore (A23187) in pulmonary endothelium
    Sajal Chakraborti
    Department of Biochemistry and Biophysics, University of Kalyani, Kalyani 741235, West Bengal, India
    Cell Signal 16:751-62. 2004
    ..Although pretreatment of the cells with pertussis toxin caused ADP ribosylation of a 41 kDa protein in the cell membrane, it did not inhibit the cPLA2 activity and AA release caused by both low and high doses of A23187...
  34. ncbi request reprint Structure and evolutionary aspects of matrix metalloproteinases: a brief overview
    Sudip Das
    Department of Biochemistry and Biophysics, University of Kalyani, Kalyani, West Bengal, India
    Mol Cell Biochem 253:31-40. 2003
    ....
  35. ncbi request reprint Solubilization, purification and reconstitution of Ca(2+)-ATPase from bovine pulmonary artery smooth muscle microsomes by different detergents: preservation of native structure and function of the enzyme by DHPC
    Amritlal Mandal
    Department of Biochemistry and Biophysics, University of Kalyani, Kalyani 741235, West Bengal, India
    Biochim Biophys Acta 1760:20-31. 2006
    ....
  36. ncbi request reprint Localization of m-calpain and calpastatin and studies of their association in pulmonary smooth muscle endoplasmic reticulum
    Krishna Samanta
    Department of Biochemistry and Biophysics, University of Kalyani, Kalyani 741235, West Bengal, India
    Biochim Biophys Acta 1770:1297-307. 2007
    ..However, such is not the case for the 80-kDa m-calpain found within the lumen of the ER because of the conspicuous absence of 28 kDa Rs of m-calpain and Cs in this locale...
  37. ncbi request reprint Role of matrix metalloprotease-2 in oxidant activation of Ca2+ ATPase by hydrogen peroxide in pulmonary vascular smooth muscle plasma membrane
    Malay Mandal
    Department of Biochemistry and Biophysics, University of Kalyani, Kalyani 741 235, India
    J Biosci 28:205-13. 2003
    ....
  38. ncbi request reprint Calcium signaling phenomena in heart diseases: a perspective
    Sajal Chakraborti
    Department of Biochemistry and Biophysics, University of Kalyani, Kalyani, 741235, West Bengal, India
    Mol Cell Biochem 298:1-40. 2007
    ..Controlling these molecular functions by different agents have been found to be beneficial in some experimental conditions...
  39. doi request reprint Mitochondrial calpain system: an overview
    Pulak Kar
    Department of Biochemistry and Biophysics, University of Kalyani, Kalyani 741235, West Bengal, India
    Arch Biochem Biophys 495:1-7. 2010
    ..This review outlines the key features of the mitochondrial calpain system, and its roles in several cellular and biochemical events under normal and some pathophysiological conditions...
  40. doi request reprint Activation of proMMP-2 by U46619 occurs via involvement of p(38)MAPK-NFκB-MT1MMP signaling pathway in pulmonary artery smooth muscle cells
    Animesh Chowdhury
    Department of Biochemistry and Biophysics, University of Kalyani, Kalyani, 741235, West Bengal, India
    Mol Cell Biochem 385:53-68. 2014
    ..Overall, U46619-induced activation of proMMP-2 is mediated via involvement of p(38)MAPK-NFκB-MT1MMP signaling pathway with concomitant downregulation of TIMP-2 expression in bovine pulmonary artery smooth muscle cells...
  41. ncbi request reprint Oxidant, antioxidant and physical exercise
    Alok K Banerjee
    Department of Physical Education, University of Kalyani, Kalyani, West Bengal, India
    Mol Cell Biochem 253:307-12. 2003
    ..Recent research suggest that supplementation of certain antioxidant nutrients are necessary for physically active individuals...
  42. ncbi request reprint Implications of calpains in health and diseases
    Sajal Chakraborti
    Department of Biochemistry and Biophysics, University of Kalyani, Kalyani 741235, West Bengal, India
    Indian J Biochem Biophys 49:316-28. 2012
    ..Herein, we present a brief overview on some implications of calpains on human health and some diseases...
  43. doi request reprint Role of phospholemman and the 70 kDa inhibitor protein in regulating Na+/K+ ATPase activity in pulmonary artery smooth muscle cells under U46619 stimulation
    Kuntal Dey
    Department of Biochemistry and Biophysics, University of Kalyani, Kalyani 741235, West Bengal, India
    FEBS Lett 587:3535-40. 2013
    ..Although phospholemman deglutathionylates the pump leading to its activation, the inhibitor is responsible for irreversible inhibition of Na(+)/K(+) ATPase in an isoform specific manner during treatment of the cells with U46619. ..