Nai Jen Chang



  1. Chang N, Lin Y, Lin C, Wang H, Hsu H, Yeh M. The repair of full-thickness articular cartilage defect using intra-articular administration of N-acetyl-D-glucosamine in the rabbit knee: randomized controlled trial. Biomed Eng Online. 2015;14:105 pubmed publisher
    ..Intra-articular GlcNAc may promote the repair of experimental FTAC defects in the rabbit knee joint model. ..
  2. Wang H, Lin T, Chang N, Hsu H, Yeh M. Continuous Passive Motion Promotes and Maintains Chondrogenesis in Autologous Endothelial Progenitor Cell-Loaded Porous PLGA Scaffolds during Osteochondral Defect Repair in a Rabbit Model. Int J Mol Sci. 2019;20: pubmed publisher
  3. Lin T, Wang H, Cheng W, Hsu H, Yeh M. Osteochondral Tissue Regeneration Using a Tyramine-Modified Bilayered PLGA Scaffold Combined with Articular Chondrocytes in a Porcine Model. Int J Mol Sci. 2019;20: pubmed publisher
    ..Thus, chondrocytes seeded in tyramine-treated bilayered scaffolds with small and large pores in the upper and lower parts, respectively, can promote osteochondral regeneration and integration for articular cartilage repair. ..
  4. Wu T, Chou Y, Chiu P, Tang M, Hu C, Yeh M. Validation of the effects of TGF-?1 on tumor recurrence and prognosis through tumor retrieval and cell mechanical properties. Cancer Cell Int. 2014;14:20 pubmed publisher
    ..In terms of clinical applications, local tumor excision followed by MMS analysis offers an opportunity to predict tumor recurrence and metastasis risks. ..
  5. Chen Y, Chang C, Lin C, Lin L, Yeh M, Jan J. Disulfide-cross-linked PEG-block-polypeptide nanoparticles with high drug loading content as glutathione-triggered anticancer drug nanocarriers. Colloids Surf B Biointerfaces. 2018;165:172-181 pubmed publisher
    ..This approach provides a platform for developing stimuli-responsive, polypeptide-based drug delivery systems with high DLC for cancer treatment. ..
  6. Huang Y, Tseng F, Chang W, Peng I, Hsieh D, Wu S, et al. Preparation of acellular scaffold for corneal tissue engineering by supercritical carbon dioxide extraction technology. Acta Biomater. 2017;58:238-243 pubmed publisher
    ..Our results suggested that the APCs developed by SCCO2 extraction technology could be an ideal and useful scaffold for corneal replacement and corneal tissue engineering. ..
  7. Tseng Y, Roan J, Ho Y, Lin C, Yeh M. An in vivo study on endothelialized vascular grafts produced by autologous biotubes and adipose stem cells (ADSCs). J Mater Sci Mater Med. 2017;28:166 pubmed publisher
    ..These small-sized ADSCs-seeded vascular biotubes may decrease the rate of intimal hyperplasia during longer implantation times and have potential clinical applications in the future. ..
  8. Lee H, Lin D, Yeh M. Phenolic Modified Ceramic Coating on Biodegradable Mg Alloy: The Improved Corrosion Resistance and Osteoblast-Like Cell Activity. Materials (Basel). 2017;10: pubmed publisher
    ..Overall, the porous MAO coating combined with gallic acid offered a novel strategy for increasing osteocompatibility. ..
  9. Lee C, Yeh M, Chang C, Chiang F, Hong C, Su W. The relationship of the anterior articular capsule to the adjacent subscapularis: An anatomic and histological study. Orthop Traumatol Surg Res. 2017;103:1265-1269 pubmed publisher

More Information


  1. Hsu K, Chang W, Yang C, Yeh M, Chang C. Factors affecting the outcomes of modified tension band wiring techniques in transverse patellar fractures. Injury. 2017;48:2800-2806 pubmed publisher
    ..Placing the wire close to the patella may prevent major loss of reduction and implant breakage. Superficially placed Kirschner wires also affect clinical outcomes by increasing the rate of minor loss of reduction. ..