Matteo Cesari

Summary

Publications

  1. pmc Biomarkers of sarcopenia in clinical trials-recommendations from the International Working Group on Sarcopenia
    Matteo Cesari
    Gerontopôle and INSERM Unit 1027, Universite de Toulouse, Toulouse, France
    J Cachexia Sarcopenia Muscle 3:181-90. 2012
  2. doi request reprint Looking for frailty in community-dwelling older persons: the Gérontopôle Frailty Screening Tool (GFST)
    B Vellas
    Gerontopole, Centre Hspitalier Universitaire De Toulouse, Toulouse, France
    J Nutr Health Aging 17:629-31. 2013
  3. doi request reprint Functional status and mortality in older women with gynecological cancer
    Matteo Cesari
    Gerontopole, Centre Hospitalier Universitaire de Toulouse, France
    J Gerontol A Biol Sci Med Sci 68:1129-33. 2013
  4. doi request reprint The stress of aging
    Matteo Cesari
    Institut du vieillissement, Universite de Toulouse, Toulouse, France
    Exp Gerontol 48:451-6. 2013
  5. doi request reprint The integration of frailty into clinical practice: preliminary results from the Gérontopôle
    J Subra
    University Department of General Medicine, 133 route de Narbonne, 31062 Toulouse Cedex, France
    J Nutr Health Aging 16:714-20. 2012
  6. pmc Oxidative damage, platelet activation, and inflammation to predict mobility disability and mortality in older persons: results from the health aging and body composition study
    Matteo Cesari
    Institut du vieillissement, Universite de Toulouse, 37 Allees Jules Guesde, 31000 Toulouse, France
    J Gerontol A Biol Sci Med Sci 67:671-6. 2012
  7. pmc ACE-inhibition and physical function: results from the Trial of Angiotensin-Converting Enzyme Inhibition and Novel Cardiovascular Risk Factors (TRAIN) study
    Matteo Cesari
    Centro per la Salute dell Anziano Area di Geriatria, Università Campus Bio Medico, Via Alvaro del Portillo 5, Rome, Italy
    J Am Med Dir Assoc 11:26-32. 2010
  8. pmc Interaction of HDL cholesterol concentrations on the relationship between physical function and inflammation in community-dwelling older persons
    Matteo Cesari
    Centro per la Salute dell Anziano Area di Geriatria, Università Campus Bio Medico, Rome, Italy
    Age Ageing 39:74-80. 2010
  9. ncbi request reprint C-reactive protein and lipid parameters in older persons aged 80 years and older
    M Cesari
    Department of Aging and Geriatric Research, University of Florida Institute on Aging, Gainesville, FL 32611, USA
    J Nutr Health Aging 13:587-93. 2009
  10. pmc Skeletal muscle and mortality results from the InCHIANTI Study
    Matteo Cesari
    Department of Gerontology, Geriatrics, and Physiatry, Catholic University of Sacred Heart, Rome, Italy
    J Gerontol A Biol Sci Med Sci 64:377-84. 2009

Detail Information

Publications73

  1. pmc Biomarkers of sarcopenia in clinical trials-recommendations from the International Working Group on Sarcopenia
    Matteo Cesari
    Gerontopôle and INSERM Unit 1027, Universite de Toulouse, Toulouse, France
    J Cachexia Sarcopenia Muscle 3:181-90. 2012
    ..However, the reasonable uncertainties (derived from exploring a novel field and the exponential acceleration of scientific progress) require the adoption of a cautious and comprehensive approach to the subject...
  2. doi request reprint Looking for frailty in community-dwelling older persons: the Gérontopôle Frailty Screening Tool (GFST)
    B Vellas
    Gerontopole, Centre Hspitalier Universitaire De Toulouse, Toulouse, France
    J Nutr Health Aging 17:629-31. 2013
    ..The use of the GFST may help at raising awareness about the importance of identifying frailty, training healthcare professionals at the detection of the syndrome, and developing preventive interventions against disabling conditions. ..
  3. doi request reprint Functional status and mortality in older women with gynecological cancer
    Matteo Cesari
    Gerontopole, Centre Hospitalier Universitaire de Toulouse, France
    J Gerontol A Biol Sci Med Sci 68:1129-33. 2013
    ..Screening tools for the identification of vulnerable older patients with cancer are needed. Aim of this study is to measure the prognostic value of multiple screening tools for the assessment of mortality risk in oncogeriatrics...
  4. doi request reprint The stress of aging
    Matteo Cesari
    Institut du vieillissement, Universite de Toulouse, Toulouse, France
    Exp Gerontol 48:451-6. 2013
    ....
  5. doi request reprint The integration of frailty into clinical practice: preliminary results from the Gérontopôle
    J Subra
    University Department of General Medicine, 133 route de Narbonne, 31062 Toulouse Cedex, France
    J Nutr Health Aging 16:714-20. 2012
    ..In this paper, we present the main characteristics of the newborn Platform for Evaluation of Frailty and Prevention of Disability (Toulouse, France)...
  6. pmc Oxidative damage, platelet activation, and inflammation to predict mobility disability and mortality in older persons: results from the health aging and body composition study
    Matteo Cesari
    Institut du vieillissement, Universite de Toulouse, 37 Allees Jules Guesde, 31000 Toulouse, France
    J Gerontol A Biol Sci Med Sci 67:671-6. 2012
    ..The aim of the present study is to assess whether biomarkers representing these mechanisms predicted major adverse health-related events in older persons...
  7. pmc ACE-inhibition and physical function: results from the Trial of Angiotensin-Converting Enzyme Inhibition and Novel Cardiovascular Risk Factors (TRAIN) study
    Matteo Cesari
    Centro per la Salute dell Anziano Area di Geriatria, Università Campus Bio Medico, Via Alvaro del Portillo 5, Rome, Italy
    J Am Med Dir Assoc 11:26-32. 2010
    ..Aim of the present study was to evaluate whether an ACE inhibitor intervention is able to significantly improve physical performance and muscle strength in a sample of older persons...
  8. pmc Interaction of HDL cholesterol concentrations on the relationship between physical function and inflammation in community-dwelling older persons
    Matteo Cesari
    Centro per la Salute dell Anziano Area di Geriatria, Università Campus Bio Medico, Rome, Italy
    Age Ageing 39:74-80. 2010
    ..the existence of a relationship among inflammation, high-density lipoprotein cholesterol (HDL-C) and physical function has been suggested...
  9. ncbi request reprint C-reactive protein and lipid parameters in older persons aged 80 years and older
    M Cesari
    Department of Aging and Geriatric Research, University of Florida Institute on Aging, Gainesville, FL 32611, USA
    J Nutr Health Aging 13:587-93. 2009
    ..Aims of the study were 1) to investigate the association of C-reactive protein (CRP) with lipid (i.e. total, LDL, and HDL cholesterol, triglycerides) concentrations, and to evaluate their predictive value for mortality in very old subjects...
  10. pmc Skeletal muscle and mortality results from the InCHIANTI Study
    Matteo Cesari
    Department of Gerontology, Geriatrics, and Physiatry, Catholic University of Sacred Heart, Rome, Italy
    J Gerontol A Biol Sci Med Sci 64:377-84. 2009
    ..Sarcopenia, the age-related loss of muscle mass, may not be an isolated process but is associated with an increase in fat mass. The aim of this study was to estimate the mortality risk of sarcopenia in the presence or absence of obesity...
  11. pmc Plasminogen activator inhibitor-1 (PAI-1): a key factor linking fibrinolysis and age-related subclinical and clinical conditions
    Matteo Cesari
    Area di Geriatria, Università Campus Bio Medico, Rome, Italy
    Cardiovasc Ther 28:e72-91. 2010
    ..The plasminogen activator system plays a key role in a wide range of physiological and pathological processes...
  12. pmc Added value of physical performance measures in predicting adverse health-related events: results from the Health, Aging And Body Composition Study
    Matteo Cesari
    Department of Aging and Geriatric Reseach, Institute on Aging, University of Florida, Gainesville, 32611, USA
    J Am Geriatr Soc 57:251-9. 2009
    ..To determine how three different physical performance measures (PPMs) combine for added utility in predicting adverse health events in elders...
  13. doi request reprint Angiotensin-converting enzyme inhibition and novel cardiovascular risk biomarkers: results from the Trial of Angiotensin Converting Enzyme Inhibition and Novel Cardiovascular Risk Factors (TRAIN) study
    Matteo Cesari
    Department of Aging and Geriatric Research, University of Florida Institute on Aging, Gainesville, 32611, USA
    Am Heart J 157:334.e1-8. 2009
    ..The present study evaluates effects of an ACE inhibitor (ie, fosinopril) intervention on novel cardiovascular risk factors...
  14. pmc Self-assessed health status, walking speed and mortality in older Mexican-Americans
    Matteo Cesari
    Department of Aging and Geriatric Research, University of Florida Institute on Aging, Gainesville, FL 32611, USA
    Gerontology 55:194-201. 2009
    ..Nevertheless, the possible interaction between them in predicting major outcomes has not been clearly explored...
  15. doi request reprint Onco-geriatric approach for the management of older patients with cancer
    Matteo Cesari
    Università Campus Bio Medico, Rome, Italy
    J Am Med Dir Assoc 12:153-9. 2011
    ..In fact, aggressive antineoplastic managements are often denied to older patients, possibly because of the common misconception suggesting older age and/or clinical complexity as absolute contraindications to advanced treatments...
  16. pmc Physical function and self-rated health status as predictors of mortality: results from longitudinal analysis in the ilSIRENTE study
    Matteo Cesari
    Dipartimento di Scienze Gerontologiche, Geriatriche e Fisiatriche, Universita Cattolica del Sacro Cuore, Roma, Italy
    BMC Geriatr 8:34. 2008
    ..Aim of the present study is to compare the predictive value for mortality of measures of physical function and SRH status, and test their possible interactions...
  17. doi request reprint Vitamin D hormone: a multitude of actions potentially influencing the physical function decline in older persons
    Matteo Cesari
    Geriatric Medicine Unit, Campus Bio Medico University, Rome, Italy
    Geriatr Gerontol Int 11:133-42. 2011
    ..Special focus is given to skeletal muscle and physical function. Limitations of available scientific evidence on the topic are also discussed...
  18. ncbi request reprint Depression and physical function: results from the aging and longevity study in the Sirente geographic area (ilSIRENTE Study)
    Andrea Russo
    Department of Gerontology, Geriatrics and Physiatry, Catholic University of Sacred Heart, Roma, Italy
    J Geriatr Psychiatry Neurol 20:131-7. 2007
    ..In conclusion, physical performance and functional status measures are significantly and negatively influenced by the presence of depression in community-dwelling older persons aged 80 years and older...
  19. ncbi request reprint Comorbidity and physical function: results from the aging and longevity study in the Sirente geographic area (ilSIRENTE study)
    Matteo Cesari
    Department of Gerontology, Geriatrics and Physiatry, Catholic University of Sacred Heart, Rome, Italy
    Gerontology 52:24-32. 2006
    ..Physical function measures have gained increased importance in the evaluation of older persons. The presence of comorbidity is a major and growing issue in geriatrics...
  20. pmc Frailty syndrome and skeletal muscle: results from the Invecchiare in Chianti study
    Matteo Cesari
    Department of Aging and Geriatric Research, College of Medicine, Institute on Aging, University of Florida, Gainesville, FL 32608, USA
    Am J Clin Nutr 83:1142-8. 2006
    ..Frailty is a common condition in elders and identifies a state of vulnerability for adverse health outcomes...
  21. ncbi request reprint Physical activity prevented functional decline among frail community-living elderly subjects in an international observational study
    Francesco Landi
    Department of Gerontology Geriatric, Catholic University Sacred Heart, Rome, Italy
    J Clin Epidemiol 60:518-24. 2007
    ..The aims of the study were to describe the prevalence of physical activity in a sample of older adults in home care in Europe and to examine the relationship between physical activity and incident disability...
  22. ncbi request reprint The ilSIRENTE study: a prospective cohort study on persons aged 80 years and older living in a mountain community of Central Italy
    Francesco Landi
    Department of Gerontology, Geriatric and Physiatric, Catholic University of Sacred Heart, Rome, Italy
    Aging Clin Exp Res 17:486-93. 2005
    ....
  23. ncbi request reprint Psychotropic medications and risk for falls among community-dwelling frail older people: an observational study
    Francesco Landi
    Department of Gerontology Geriatrics, Catholic University of Sacred Heart, Rome, Italy
    J Gerontol A Biol Sci Med Sci 60:622-6. 2005
    ..Although a small number of falls have a single cause, the majority have many different causes resulting from the interactions between intrinsic or extrinsic risk factors...
  24. ncbi request reprint Sarcopenia, obesity, and inflammation--results from the Trial of Angiotensin Converting Enzyme Inhibition and Novel Cardiovascular Risk Factors study
    Matteo Cesari
    Department of Aging and Geriatric Research, College of Medicine, Institute on Aging, University of Florida, Gainesville, FL, USA
    Am J Clin Nutr 82:428-34. 2005
    ..Age-related body-composition changes are associated with health-related outcomes in elders. This relation may be explained by inflammation and hemostatic abnormalities...
  25. doi request reprint Walking one hour or more per day prevented mortality among older persons: results from ilSIRENTE study
    Francesco Landi
    Department of Gerontology, Geriatrics and Physiatry, Catholic University of Sacred Heart, Roma, Italy
    Prev Med 47:422-6. 2008
    ..The aim of the present study was to explore the relationship between regular walking and the risk of all-cause death in a large population of frail and very old people living in community...
  26. ncbi request reprint Indwelling urethral catheter and mortality in frail elderly women living in community
    Francesco Landi
    Department of Gerontology Geriatric and Physiatric, Catholic University of Sacred Heart, Rome, Italy
    Neurourol Urodyn 23:697-701. 2004
    ..The aims of present study were to describe the prevalence of bladder catheter in a population of older women living in community and to examine the relationship between urinary catheter and mortality...
  27. ncbi request reprint Anemia and cognitive performance in hospitalized older patients: results from the GIFA study
    Valentina Zamboni
    Department of Gerontology, Geriatrics and Physiatry, Catholic University of Sacred Heart, Rome, Italy
    Int J Geriatr Psychiatry 21:529-34. 2006
    ..Anemia represents a major risk factor for adverse health-related events in older persons. The aim of this study was to evaluate the association between hemoglobin levels/anemia and cognitive function in hospitalized older persons...
  28. ncbi request reprint The effects of cognitive impairment on mortality among hospitalized patients with heart failure
    Giuseppe Zuccala
    Department of Gerontology, Catholic University of the Sacred Heart, Rome, Italy
    Am J Med 115:97-103. 2003
    ..Because cerebral metabolic abnormalities have been associated with reduced survival in younger patients with advanced heart failure, we assessed the effect of cognitive impairment on the survival of older patients with heart failure...
  29. ncbi request reprint Anemia and recovery from disability in activities of daily living in hospitalized older persons
    Cinzia Maraldi
    Department of Aging and Geriatric Research, College of Medicine, Institute on Aging, University of Florida, Gainesville, FL 32608, USA
    J Am Geriatr Soc 54:632-6. 2006
    ..To evaluate the predictive value of hemoglobin levels upon hospital admission on recovery from activity of daily living (ADL) disability during hospital stay in older patients...
  30. ncbi request reprint Comorbidity and social factors predicted hospitalization in frail elderly patients
    Francesco Landi
    Instituto di Medicina Interna e Geriatria, Centro Medicina dell Invecchiamento, Universita Cattolica del Sacro Cuore, Rome, Italy
    J Clin Epidemiol 57:832-6. 2004
    ....
  31. ncbi request reprint Impact of inflammation on the relationship among alcohol consumption, mortality, and cardiac events: the health, aging, and body composition study
    Cinzia Maraldi
    Department of Aging and Geriatric Research, College of Medicine, Institute on Aging, University of Florida, 1329 SW 16th St, Gainesville, FL 32608, USA
    Arch Intern Med 166:1490-7. 2006
    ..We investigated the relationship of alcohol intake with all-cause mortality and cardiac events and evaluated whether this relationship is mediated or modified by inflammatory markers...
  32. ncbi request reprint Physical function and perceived quality of life in older persons
    Oriana Fusco
    Department of Gerontology, Geriatrics, and Physical Medicine, Catholic University of the Sacred Heart, Rome, Italy
    Aging Clin Exp Res 24:68-73. 2012
    ..The aim of the study was to verify which specific physical function measure is a more important predictor of quality of life in these individuals...
  33. ncbi request reprint Lipoprotein peroxidation and mobility limitation: results from the Health, Aging, and Body Composition Study
    Matteo Cesari
    Department of Aging and Geriatric Research, College of Medicine, Institute on Aging, University of Florida, Gainesville 32608, USA
    Arch Intern Med 165:2148-54. 2005
    ..The aim of this study was to assess the predictive value of a lipoprotein peroxidation marker, oxidized low-density lipoprotein (oxLDL) for incident mobility limitation (ML)...
  34. ncbi request reprint Anemia, physical disability, and survival in older patients with heart failure
    Cinzia Maraldi
    Department of Aging and Geriatric Research, College of Medicine, Institute on Aging, University of Florida, Gainesville, Florida 32608, USA
    J Card Fail 12:533-9. 2006
    ..The effect of anemia on functional ability in heart failure has not been described. We evaluated the relationship of anemia, physical disability, and survival in patients with heart failure...
  35. ncbi request reprint HDL-cholesterol and physical performance: results from the ageing and longevity study in the sirente geographic area (ilSIRENTE Study)
    Francesco Landi
    Department of Gerontology, Geriatrics and Physiatry, Catholic University of Sacred Heart, Roma, Italy
    Age Ageing 36:514-20. 2007
    ..We evaluate the relationship of HDL-cholesterol with measures of physical performance, muscle strength, and functional status in older persons aged 80years or older...
  36. ncbi request reprint Insulin-like growth factor-binding protein 3 and hemoglobin concentration in older persons living in the community
    Francesco Landi
    Department of Gerontology and Geriatrics, Catholic University of Sacred Heart, Roma, Italy
    Int J Hematol 85:294-9. 2007
    ..This finding suggests that the growth hormone/IGF axis may play an important role in hematopoiesis, and it may be implicated in the age-related decline in hemoglobin concentration...
  37. ncbi request reprint Prognostic value of usual gait speed in well-functioning older people--results from the Health, Aging and Body Composition Study
    Matteo Cesari
    Department of Aging and Geriatric Research, College of Medicine, Institute on Aging, University of Florida, Gainesville, Florida 32608, USA
    J Am Geriatr Soc 53:1675-80. 2005
    ..To define clinically relevant cutpoints for usual gait speed and to investigate their predictive value for health-related events in older persons...
  38. ncbi request reprint In a prospective observational study, influenza vaccination prevented hospitalization among older home care patients
    Francesco Landi
    Department of Gerontology Geriatric and Physiatric, Catholic University of Sacred Heart, 00168 Rome, Italy
    J Clin Epidemiol 59:1072-7. 2006
    ..The aim of the study is (1) to describe the prevalence of vaccination against influenza in older home care patients and (2) to investigate the protective effect of influenza vaccination for hospitalization events...
  39. pmc Angiotensin-converting enzyme inhibitor use by older adults is associated with greater functional responses to exercise
    Thomas W Buford
    Department of Aging and Geriatric Research, University of Florida College of Medicine, Gainesville, Florida 32607, USA
    J Am Geriatr Soc 60:1244-52. 2012
    ..To assess the association between angiotensin converting enzyme inhibitors (ACEis) and improvements in the physical function of older adults in response to chronic exercise training...
  40. ncbi request reprint Serum high-density lipoprotein cholesterol levels and mortality in frail, community-living elderly
    Francesco Landi
    Department of Gerontology and Geriatrics, Catholic University of Sacred Heart, Rome, Italy
    Gerontology 54:71-8. 2008
    ..High-density lipoprotein (HDL) cholesterol has been hypothesized to be a reliable marker of frailty and poor prognosis among the oldest elderly...
  41. ncbi request reprint Depression and adverse drug reactions among hospitalized older adults
    Graziano Onder
    Centro Medicina dell Invecchiamento, Universita Cattolica del Sacro Cuore, Policlinico A Gemelli, L go Francesco Vito 1, 00168 Rome, Italy
    Arch Intern Med 163:301-5. 2003
    ..The aim of this study was to assess whether depression may be a risk factor for adverse drug reactions (ADRs) among hospitalized older adults...
  42. ncbi request reprint Diabetes mellitus, glycemic control, and incident depressive symptoms among 70- to 79-year-old persons: the health, aging, and body composition study
    Cinzia Maraldi
    Institute on Aging, University of Florida, USA
    Arch Intern Med 167:1137-44. 2007
    ..The causal mechanisms and temporal sequence of this association have not been clearly delineated. This study investigated the prospective relationship between DM and depressive symptoms...
  43. ncbi request reprint Association between daily pain and physical function among old-old adults living in the community: results from the ilSIRENTE study
    Graziano Onder
    Department of Gerontology, Catholic University of Sacred Heart, Rome, Italy
    Pain 121:53-9. 2006
    ..In conclusion, the present study shows that among old-old subjects living in the community, daily pain is highly prevalent and that this condition is associated with impaired muscle strength and physical performance...
  44. ncbi request reprint Free insulin-like growth factor-I and cognitive function in older persons living in community
    Francesco Landi
    Department of Gerontology and Geriatrics, Catholic University of Sacred Heart, 00168, Roma, Italy
    Growth Horm IGF Res 17:58-66. 2007
    ..Increasing evidences from experimental and human studies suggest that the activity of the growth hormone (GH/insulin-like growth factor-I) axis may contribute to the age-related cognitive decline and poor cognition in late life...
  45. ncbi request reprint Physical activity and risk of cognitive impairment among older persons living in the community
    Francesco Landi
    Department of Gerontology and Geriatrics, Catholic University of the Sacred Heart, Rome, Italy
    Aging Clin Exp Res 19:410-6. 2007
    ..The aim of the present study was to evaluate the relationship of lifetime physical activity with cognitive performance in older persons aged 80 years or older...
  46. ncbi request reprint Body mass index, free insulin-like growth factor I, and physical function among older adults: results from the ilSIRENTE study
    Graziano Onder
    Department of Geriatrics, Catholic University of Sacred Heart, Rome, Italy
    Am J Physiol Endocrinol Metab 291:E829-34. 2006
    ..By contrast, no association was observed between IGFBP-3 and study outcomes, independently of BMI. In conclusion, high IGF-I level is associated with better physical function in older persons with obesity, but not in nonobese subjects...
  47. ncbi request reprint Use of ACE inhibitors is associated with elevated levels of IGFBP-3 among hypertensive older adults: results from the IlSIRENTE study
    Graziano Onder
    Department of Geriatrics, Catholic University of the Sacred Heart, Rome, Italy
    Eur J Clin Pharmacol 63:389-95. 2007
    ..However, this relationship has only rarely been investigated in humans. The aim of the present cross-sectional study was to assess the association of ACE inhibitors with free IGF-1 and IGFBP-3 in the blood of older hypertensive adults...
  48. ncbi request reprint Predictors of rehabilitation outcomes in frail patients treated in a geriatric hospital
    Francesco Landi
    Department of Gerontology and Geriatrics, Catholic University of Sacred Heart, Rome, Italy
    J Am Geriatr Soc 50:679-84. 2002
    ..To evaluate the effect of medical indicators of health status on functional gain during rehabilitation of frail older patients...
  49. ncbi request reprint Effects of influenza vaccination on mortality among frail, community-living elderly patients: an observational study
    Francesco Landi
    Department of Gerontology, Geriatric and Physiatric Medicine, Catholic University of the Sacred Heart, Roma, Italy
    Aging Clin Exp Res 15:254-8. 2003
    ..The aims of the present study were to describe the prevalence of vaccination against influenza in a population of older people living in the community, and to examine the relationship between influenza vaccination and mortality...
  50. ncbi request reprint Anemia is associated with depression in older adults: results from the InCHIANTI study
    Graziano Onder
    Geriatric Department, Catholic University of the Sacred Heart, Rome, Italy
    J Gerontol A Biol Sci Med Sci 60:1168-72. 2005
    ..The objective of this study was to examine whether depressive symptoms and anemia are associated among older adults living in the community...
  51. ncbi request reprint Use of angiotensin-converting enzyme inhibitors and variations in cognitive performance among patients with heart failure
    Giuseppe Zuccala
    Catholic University, Department of Gerontology, Geriatrics, and Physiatrics, L go F Vito, I 00168 Rome, Italy
    Eur Heart J 26:226-33. 2005
    ..Our aim was to assess whether starting treatment with ACE-inhibitors might improve cognition in patients with heart failure...
  52. pmc The aging process and potential interventions to extend life expectancy
    Matteo Tosato
    Department of Gerontology, Geriatrics and Physiatry, Catholic University of Sacred Heart, Rome, Italy
    Clin Interv Aging 2:401-12. 2007
    ..The present review provides an overlook of the most commonly accepted theories of aging, providing current evidence of those interventions aimed at modifying the aging process...
  53. ncbi request reprint Physical activity and mortality in frail, community-living elderly patients
    Francesco Landi
    Department of Gerontology, Geriatrics and Physiatrics, Catholic University of the Sacred Heart, Rome, Italy
    J Gerontol A Biol Sci Med Sci 59:833-7. 2004
    ..The authors describe the prevalence of moderate-intensity physical activity in a population of older persons living in the community. In addition, they explore the relationship between physical activity and mortality...
  54. ncbi request reprint Non-steroidal anti-inflammatory drug (NSAID) use and Alzheimer disease in community-dwelling elderly patients
    Francesco Landi
    Department of Gerontology Geriatric and Physiatric, Catholic University of the Sacred Heart, Rome, Italy
    Am J Geriatr Psychiatry 11:179-85. 2003
    ..The aim of the present study was to examine the relationship between NSAIDs use and AD in a large sample of community-dwelling elderly people...
  55. ncbi request reprint Use of calcium antagonists and worsening renal function in patients receiving angiotensin-converting-enzyme inhibitors
    Giuseppe Zuccala
    Catholic University of the Sacred Heart, L go F Vito 1, 00168, Rome, Italy
    Eur J Clin Pharmacol 58:695-9. 2003
    ....
  56. ncbi request reprint Physical exercise and comorbidity. Results from the Fitness and Arthritis in Seniors Trial (FAST)
    Irene Mangani
    Department of Aging and Geriatric Research, College of Medicine, Institute on Aging, University of Florida, Gainesville, FL, USA
    Aging Clin Exp Res 18:374-80. 2006
    ..The impact of comorbidity on the benefits from physical exercise has not been clearly investigated. Elders with comorbidity may benefit from physical exercise to preserve physical function...
  57. pmc Effects of antioxidant supplementation on the aging process
    Domenico Fusco
    Department of Gerontology, Geriatrics and Physiatry, Catholic University of Sacred Heart, Rome, Italy
    Clin Interv Aging 2:377-87. 2007
    ..The aim of this paper is to provide the main basis from which future studies should start and indicate which the main limitations that need to be addressed are...
  58. doi request reprint Angiotensin-converting enzyme inhibitors and Alzheimer's disease progression in older adults: results from the Réseau sur la Maladie d'Alzheimer Français cohort
    Maria E Soto
    Department of Geriatric Medicine, Gerontopole, CHU Toulouse University Hospital, Toulouse, France INSERM, UMR1027, Toulouse, France
    J Am Geriatr Soc 61:1482-8. 2013
    ..To assess whether angiotensin-converting enzyme inhibitor (ACE-I) treatment is associated with less cognitive decline in older adults with Alzheimer's disease (AD) than in those using other hypertensive or no drugs...
  59. ncbi request reprint Physical performance measures as predictors of mortality in a cohort of community-dwelling older French women
    Yves Rolland
    Service de Medecine Interne et de Gerontologie Clinique, Hopital La Grave Casselardit, 31300, Toulouse, France
    Eur J Epidemiol 21:113-22. 2006
    ..Increased risk of death was partly explained by baseline health status and was absent in the healthiest elderly...
  60. ncbi request reprint Pain and its relation to depressive symptoms in frail older people living in the community: an observational study
    Francesco Landi
    Istituto di Medicina Interna e Geriatria, Universita Cattolica del Sacro Cuore, Rome, Italy
    J Pain Symptom Manage 29:255-62. 2005
    ..Treatment models that put together the assessment and the treatment of both pain and depression are indispensable for better outcomes...
  61. ncbi request reprint Potentially reversible risk factors and urinary incontinence in frail older people living in community
    Francesco Landi
    Institute of Internal Medicine, Department of Gerontology Geriatric and Physiatric, Catholic University of Sacred Heart, Largo Agostino Gemelli 8, I 00168 Rome, Italy
    Age Ageing 32:194-9. 2003
    ..However, few data exist concerning the potentially reversible causes of this condition among frail community-dwelling older individuals...
  62. ncbi request reprint Inappropriate medication use among hospitalized older adults in Italy: results from the Italian Group of Pharmacoepidemiology in the Elderly
    Graziano Onder
    Centro Medicina dell Invecchiamento, Universita Cattolica del Sacro Cuore, Policlinico A Gemelli, L go Francesco Vito 1, 00168, Roma, Italy
    Eur J Clin Pharmacol 59:157-62. 2003
    ..To determine the prevalence of inappropriate medication use among hospitalized older adults and to identify predictors of this use...
  63. ncbi request reprint Oxidative damage and platelet activation as new predictors of mobility disability and mortality in elders
    Matteo Cesari
    Department of Aging and Geriatric Research, College of Medicine, Institute on Aging, University of Florida, Gainesville, Florida 36208, USA
    Antioxid Redox Signal 8:609-19. 2006
    ..g., physical activity, dietary restriction, smoking cessation) play an important role in the reduction of oxidative damage levels and are associated with improved physical performance and muscle strength...
  64. ncbi request reprint Prevalence and risk factors for falls in an older community-dwelling population
    Matteo Cesari
    Department of Gerontology, Geriatrics, and Physiatric Sciences, Catholic University of the Sacred Heart, Rome, Italy
    J Gerontol A Biol Sci Med Sci 57:M722-6. 2002
    ..The aim of this study was to determine the prevalence of falls and related intrinsic and extrinsic risk factors in a community-dwelling older population...
  65. pmc Effects of a weight loss plus exercise program on physical function in overweight, older women: a randomized controlled trial
    Stephen D Anton
    Department of Aging and Geriatric Research, University of Florida, Gainesville, USA
    Clin Interv Aging 6:141-9. 2011
    ..This study tested whether a weight loss program combined with moderate exercise could improve physical function in obese, older adult women...
  66. ncbi request reprint Benzodiazepines and the risk of urinary incontinence in frail older persons living in the community
    Francesco Landi
    Department of Gerontology Geriatrics and Physiatrics, Catholic University of Sacred Heart, Rome, Italy
    Clin Pharmacol Ther 72:729-34. 2002
    ..The aim of this study was to estimate the risk of urinary incontinence associated with the use of oxidative or nonoxidative benzodiazepines...
  67. ncbi request reprint Effects of an occupational therapy program on functional outcomes in older stroke patients
    Francesco Landi
    Department of Gerontology Geriatric and Physiatric, Catholic University of Sacred Heart, Rome, Italy
    Gerontology 52:85-91. 2006
    ..Objective: To evaluate the efficacy of occupational therapy programs in patients with a recent stroke...
  68. ncbi request reprint Adverse drug reactions and cognitive function among hospitalized older adults
    Graziano Onder
    Centro Medicina dell Invecchiamento, Universita Cattolica del Sacro Cuore, Rome, Italy
    Eur J Clin Pharmacol 58:371-7. 2002
    ..To explore the relationship between cognitive function and the detection of adverse drug reactions (ADRs) and to evaluate whether cognitive function could influence the association between age and ADRs...
  69. ncbi request reprint Topical treatment of pressure ulcers with nerve growth factor: a randomized clinical trial
    Francesco Landi
    Department of Geriatrics, Catholic University of the Sacred Heart, Rome, Italy
    Ann Intern Med 139:635-41. 2003
    ..Management options for pressure ulcers include local wound care; surgical repair; and, more recently, topical application of growth factors...
  70. doi request reprint Gas exchanges and pulmonary vascular abnormalities at different stages of chronic liver disease
    Simone Scarlata
    Unit of Respiratory Pathophysiology, Universita Campus BioMedico, Rome, Italy
    Liver Int 31:525-33. 2011
    ..Aim of this study was to compare pulmonary capillary volumes and gas exchange efficiency of CLD patients with and without cirrhosis...
  71. pmc Rationale for antioxidant supplementation in sarcopenia
    Francesco Cerullo
    Dipartimento di Scienze Gerontologiche, Geriatriche e Fisiatriche, Universita Cattolica del Sacro Cuore, Largo Francesco Vito 1, 00168 Roma, Italy
    J Aging Res 2012:316943. 2012
    ..Aim of the present paper is to discuss present evidence related to possible benefits of oral antioxidants in the prevention and treatment of sarcopenia...
  72. doi request reprint Spontaneous resolution of a giant pulmonary bulla in an older woman: role of functional assessment
    Simone Scarlata
    Centro per la Salute dell Anziano Area di Geriatria, Università Campus Bio Medico, Rome, Italy
    Respiration 81:59-62. 2011
    ..Interestingly, the reported case is characterized by a negligible improvement in respiratory function parameters, despite a substantial increase in the 6-min walking test and the oxygen arteriolar partial pressure...
  73. ncbi request reprint Designing Phase II B trials in sarcopenia: the best target population
    M Pahor
    Department of Aging and Geriatric Research, University of Florida Institute on Aging, Gainesville, FL, USA
    J Nutr Health Aging 15:725-30. 2011
    ....