Research Topics
| R N CardinalSummaryAffiliation: Centre for Online Health Publications
|
Detail Information
Publications
Hippocampal lesions facilitate instrumental learning with delayed reinforcement but induce impulsive choice in ratsTimothy H C Cheung
Department of Experimental Psychology, University of Cambridge, Downing Street, Cambridge CB2 3EB, UK
BMC Neurosci 6:36. 2005....
Impulsive choice induced in rats by lesions of the nucleus accumbens coreR N Cardinal
Department of Experimental Psychology, University of Cambridge, Downing Street, Cambridge CB2 3EB, UK
Science 292:2499-501. 2001..Thus, dysfunction of the nucleus accumbens core may be a key element in the neuropathology of impulsivity...
Osteomalacia and vitamin D deficiency in a psychiatric rehabilitation unit: case report and surveyRudolf N Cardinal
Behavioural and Clinical Neurosciences Institute and Department of Psychiatry, University of Cambridge, Addenbrooke s Hospital, Hills Road, Cambridge, CB2 0QQ, UK
BMC Res Notes 2:82. 2009..CONCLUSION: We advocate vitamin D screening in all patients admitted to psychogeriatric units, and discuss treatment options given the current problems affecting high-dose vitamin D supply to the United Kingdom...
Neural systems implicated in delayed and probabilistic reinforcementRudolf N Cardinal
Department of Experimental Psychology, University of Cambridge, Downing Street, Cambridge, UK
Neural Netw 19:1277-301. 2006....
Effects of lesions of the nucleus accumbens core on choice between small certain rewards and large uncertain rewards in ratsRudolf N Cardinal
Department of Experimental Psychology, University of Cambridge, Downing Street, Cambridge CB2 3EB, UK
BMC Neurosci 6:37. 2005..We examined the effects of excitotoxic lesions of the AcbC on probabilistic choice in rats...
Nucleus accumbens core lesions retard instrumental learning and performance with delayed reinforcement in the ratRudolf N Cardinal
Department of Experimental Psychology, University of Cambridge, Downing Street, Cambridge CB2 3EB, UK
BMC Neurosci 6:9. 2005....
Limbic corticostriatal systems and delayed reinforcementRudolf N Cardinal
Department of Experimental Psychology, University of Cambridge, Downing Street, Cambridge CB2 3EB, UK
Ann N Y Acad Sci 1021:33-50. 2004....
Whisker: a client-server high-performance multimedia research control systemRudolf N Cardinal
Behavioural and Clinical Neuroscience Institute, Department of Psychiatry, University of Cambridge, Cambridge, England
Behav Res Methods 42:1059-71. 2010..This system is flexible and reliable, although there are potential disadvantages in terms of complexity. Its design, features, and performance are described...
Role of the anterior cingulate cortex in the control over behavior by Pavlovian conditioned stimuli in ratsRudolf N Cardinal
Department of Experimental Psychology, University of Cambridge, Downing Street, Cambridge CB2 3EB, United Kingdom
Behav Neurosci 117:566-87. 2003..It is suggested that the ACC is not critical for stimulus-reward learning per se, but is required to discriminate multiple stimuli on the basis of their association with reward...
Local analysis of behaviour in the adjusting-delay task for assessing choice of delayed reinforcementRudolf N Cardinal
Department of Experimental Psychology University of Cambridge, UK
Neural Netw 15:617-34. 2002..Consequently, the use of explicit analysis of delay sensitivity is advocated in future research on delayed reinforcement...
Distinct changes in cortical acetylcholine and noradrenaline efflux during contingent and noncontingent performance of a visual attentional taskJ W Dalley
Department of Experimental Psychology, University of Cambridge, Cambridge, United Kingdom CB2 3EB
J Neurosci 21:4908-14. 2001....
Differential involvement of NMDA, AMPA/kainate, and dopamine receptors in the nucleus accumbens core in the acquisition and performance of pavlovian approach behaviorP Di Ciano
Department of Experimental Psychology, University of Cambridge, Cambridge, CB2 3EB, United Kingdom
J Neurosci 21:9471-7. 2001....
Nucleus accumbens dopamine depletion impairs both acquisition and performance of appetitive Pavlovian approach behaviour: implications for mesoaccumbens dopamine functionJ A Parkinson
Department of Experimental Psychology, University of Cambridge, Downing Street, CB2 3EB, Cambridge, UK
Behav Brain Res 137:149-63. 2002..This difference in lesion-induced impairment implies that mesoaccumbens dopamine may play differential roles in the learning and performance of preparatory Pavlovian conditioning...
Double dissociation between serotonergic and dopaminergic modulation of medial prefrontal and orbitofrontal cortex during a test of impulsive choiceCatharine A Winstanley
Department of Experimental Psychology, University of Cambridge, Downing Site, Cambridge, CB2 3EB, UK
Cereb Cortex 16:106-14. 2006..These data suggest a double dissociation between serotonergic and dopaminergic modulation of impulsive decision-making within distinct areas of frontal cortex...
Contrasting roles of basolateral amygdala and orbitofrontal cortex in impulsive choiceCatharine A Winstanley
Department of Experimental Psychology, University of Cambridge, Downing Site, Cambridge CB2 3EB, United Kingdom
J Neurosci 24:4718-22. 2004..This is the first time that lesions to these two structures have produced opposite behavioral effects, indicating their distinct contributions to cognition...
Effects of selective excitotoxic lesions of the nucleus accumbens core, anterior cingulate cortex, and central nucleus of the amygdala on autoshaping performance in ratsRudolf N Cardinal
Department of Experimental Psychology, University of Cambridge, United Kingdom
Behav Neurosci 116:553-67. 2002..CeA lesions had no effect on performance. Thus, the CeA is required for learning, but not expression, of a conditioned approach response, implying that it makes a specific contribution to the learning of stimulus-reward associations...
Prefrontal executive and cognitive functions in rodents: neural and neurochemical substratesJeffrey W Dalley
Department of Experimental Psychology, University of Cambridge, Downing Street, Cambridge CB2 3EB, UK
Neurosci Biobehav Rev 28:771-84. 2004....
Neural and psychological mechanisms underlying appetitive learning: links to drug addictionRudolf N Cardinal
Department of Experimental Psychology, University of Cambridge, Downing Street, Cambridge CB2 3EB, UK
Curr Opin Neurobiol 14:156-62. 2004..This process may be one of several contributing to addiction, and it may be amenable to pharmacological intervention...
Appetitive behavior: impact of amygdala-dependent mechanisms of emotional learningBarry J Everitt
Department of Experimental Psychology, University of Cambridge, Cambridge CB2 3EB, UK
Ann N Y Acad Sci 985:233-50. 2003....
Emotion and motivation: the role of the amygdala, ventral striatum, and prefrontal cortexRudolf N Cardinal
Department of Experimental Psychology, University of Cambridge, Downing Street, Cambridge CB2 3EB, UK
Neurosci Biobehav Rev 26:321-52. 2002....
Explaining the escalation of drug use in substance dependence: models and appropriate animal laboratory testsGerald Zernig
Experimental Psychiatry Unit, Department of Psychiatry, Medical University Innsbruck, Innsbruck, Austria
Pharmacology 80:65-119. 2007..The review concludes by making suggestions on how to improve the current behavioral experimental approaches...
