Comparison of the anti-inflammatory and therapeutic actions of PPAR-gamma agonists rosiglitazone and troglitazone in experimental colitisK Celinski
Department of Gastroenterology, Medical University, Lublin, Poland
J Physiol Pharmacol 63:631-40. 2012
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- Effects of peroxisome proliferator-activated receptors-gamma ligands on dextran sodium sulphate-induced colitis in rats
K Celinski
Department of Gastroenterology, Medical University of Lublin, Poland
J Physiol Pharmacol 62:347-56. 2011
..The positive effects of rosiglitazone on expression of IL-10 were also demonstrated. During the short period of observation, BADGE did not increase histopathological inflammatory markers...
- Non-variceal upper gastrointestinal bleeding--guidelines on management
K Celinski
Department of Gastroenterology, Medical University of Lublin, Poland
J Physiol Pharmacol 59:215-29. 2008
..The paper work also presents the newest directives for pharmacological treatment and guidelines for possible surgical treatment...
- Influence of the peroxisome proliferator-activated receptor gamma (PPAR-γ) agonist, rosiglitazone and antagonist, biphenol-A-diglicydyl ether (BADGE) on the course of inflammation in the experimental model of colitis in rats
T Dworzanski
Department of Gastroenterology, Medical University of Lublin, Lublin, Poland
J Physiol Pharmacol 61:683-93. 2010
..Rosiglitazone reduces inflammation by decreasing the expression of IL-6 and TNF-α. BADGE administered with rosiglitazone blocks the activity of PPAR-γ and abolishes the protective effects of PPAR-γ agonist...
- Effects of melatonin and tryptophan on healing of gastric and duodenal ulcers with Helicobacter pylori infection in humans
K Celinski
Department of Gastroenterology, Medical University of Lublin, Poland
J Physiol Pharmacol 62:521-6. 2011
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- Genetic polymorphism of alcohol-metabolizing enzyme and alcohol dependence in Polish men
H Cichoz-Lach
Department of Gastroenterology, Medical University of Lublin, Poland
Braz J Med Biol Res 43:257-61. 2010
..However, subjects with ADH1C*1/*1 and CYP2E1*c1/*c2 genotypes become alcohol dependent at a considerably younger age than the subjects with ADH1C*1/*2, ADH1C*2/*2 and CYP2E1*c1/*c1 genotypes...
- The effects of L-tryptophan and melatonin on selected biochemical parameters in patients with steatohepatitis
H Cichoz-Lach
Department of Gastroenterology, Medical University of Lublin, Lublin, Poland
J Physiol Pharmacol 61:577-80. 2010
..The present study suggests that melatonin and tryptophan have the significant impact on the reduction in plasma levels of proinflammatory cytokines and may be useful in the treatment of patients with NASH...
- The role of adenosine receptors for pancreatic blood flow in caerulein-induced acute pancreatitis
K Celinski
Department of Gastroenterology, Medical University of Lublin, Lublin, Poland
Rocz Akad Med Bialymst 48:57-60. 2003
..The aim of our study was to evaluate the possible influence of adenosine receptors agonists and antagonists on pancreatic blood flow (PBF) and the development of acute pancreatitis (AP) in rats...
- Impact of interferon-alpha therapy on the serum level of alpha-fetoprotein in patients with chronic viral hepatitis
B Kasztelan-Szczerbinska
Department of Gastroenterology, Medical University of Lublin, Lublin, Poland
Rocz Akad Med Bialymst 48:74-7. 2003
..Assessment of the long-term effect of interferon-alpha (IFN-alpha) treatment on the serum level of hepatocarcinogenesis marker--alpha-fetoprotein (AFP), in patients (pts) with chronic viral hepatitis (c.v.h.) type B and C...
- RAS inhibitors decrease apoptosis of acinar cells and increase elimination of pancreatic stellate cells after in the course of experimental chronic pancreatitis induced by dibutyltin dichloride
A Madro
Department of Gastroenterology with Endoscopic Unit, Medical University of Lublin, Poland
J Physiol Pharmacol 59:239-49. 2008
..This reaction was weak in groups of rat treated with DBTC and RAS inhibitors. Treatment of CP rats with RAS inhibitors alleviate apoptosis of pancreatic acinar cells and induces PSCs elimination...
Can we expect progress in the treatment of fibrosis in the course of chronic pancreatitis?A Madro
Department of Gastroenterology with Endoscopic Unit, Medical University of Lublin, Lublin, Poland
Adv Med Sci 56:132-7. 2011
..The findings of many recent experimental studies are highly encouraging; however, their efficacy should be confirmed in well-designed clinical trials...
- Therapeutic endoscopy in gastroenterology
K Celinski
Department of Gastroenterology, Medical University of Lublin, Lublin, Poland
J Physiol Pharmacol 58:33-41. 2007
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- Pathophysiology of portal hypertension
H Cichoz-Lach
Department of Gastroenterology, Medical University of Lublin, Poland
J Physiol Pharmacol 59:231-8. 2008
..Understanding the pathophysiology of portal hypertension could be of great utility in preventing and curing the complications of portal hypertension, such as esophageal varices, hepatic encephalopathy, ascites...
- Prevalence of spontaneous bacterial peritonitis in asymptomatic inpatients with decompensated liver cirrhosis - a pilot study
B Kasztelan-Szczerbinska
Department of Gastroenterology and Endoscopy Unit, Medical University of Lublin, Lublin, Poland
Adv Med Sci 56:13-7. 2011
..To assess the prevalence of spontaneous bacterial peritonitis (SBP) in asymptomatic patients with decompensated liver cirrhosis...
- The role of adenosine A2a receptors in experimental acute pancreatitis
K Celinski
Department of Gastroenterology, Medical University, Lublin ul Solarza 16, 20 815 Lublin, Poland
Adv Med Sci 51:105-10. 2006
..The aim was to evaluate the effects of the adenosine A2a receptor agonist and antagonist in the severe, taurocholate-induced experimental acute pancreatitis (EAP)...
- Genetic polymorphism of alcohol dehydrogenase 3 in digestive tract alcohol damage
H Cichoz-Lach
Department of Gastroenterology, Medical University of Lublin, Poland
Hepatogastroenterology 54:1222-7. 2007
..The aim of the present study was to find in the Polish population the ADH3 genotypes, which are likely to be responsible for higher susceptibility to alcohol disease of the liver and chronic alcohol pancreatitis...
- Altered basal and postprandial plasma melatonin, gastrin, ghrelin, leptin and insulin in patients with liver cirrhosis and portal hypertension without and with oral administration of melatonin or tryptophan
K Celinski
Department of Gastroeneterology, Medical University of Lublin, Lublin, Poland
J Pineal Res 46:408-14. 2009
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