D J Castro

Summary

Publications

  1. ncbi request reprint Troponin I and risk stratification of patients with acute nonmassive pulmonary embolism
    D Jimenez
    Dept of Respiratory, Ramon y Cajal Hospital, Madrid, Spain
    Eur Respir J 31:847-53. 2008
  2. doi request reprint Prognostic significance of multidetector computed tomography in normotensive patients with pulmonary embolism: rationale, methodology and reproducibility for the PROTECT study
    David Jimenez
    Respiratory Department, Ramon y Cajal Hospital, IRYCIS, 28034, Madrid, Spain
    J Thromb Thrombolysis 34:187-92. 2012
  3. doi request reprint Apixaban: an oral direct factor-xa inhibitor
    David Jimenez
    Respiratory Department, Ramon y Cajal Hospital, Madrid, Spain
    Adv Ther 29:187-201. 2012
  4. doi request reprint Prognostic models for selecting patients with acute pulmonary embolism for initial outpatient therapy
    David Jimenez
    Respiratory Department and Medicine Department, Ramón y Cajal Hospital and Alcalá de Henares University, Madrid, Spain
    Curr Opin Pulm Med 14:414-21. 2008
  5. ncbi request reprint [Anti-factor Xa activity of enoxaparin for thromboprophylaxis in nonsurgical patients is dependent on body mass]
    David Jimenez
    Servicio de Neumología Hospital Ramón y Cajal Madrid España
    Arch Bronconeumol 44:660-3. 2008
  6. doi request reprint Troponin-based risk stratification of patients with acute nonmassive pulmonary embolism: systematic review and metaanalysis
    David Jimenez
    Respiratory Department, Ramon y Cajal Hospital, 28034 Madrid, Spain
    Chest 136:974-82. 2009
  7. doi request reprint Association of anaemia and mortality in patients with acute pulmonary embolism
    David Jimenez
    Respiratory Department, Ramon y Cajal Hospital, Madrid, Spain
    Thromb Haemost 102:153-8. 2009
  8. doi request reprint Prognostic significance of deep vein thrombosis in patients presenting with acute symptomatic pulmonary embolism
    David Jimenez
    Respiratory Department, Ramon y Cajal Hospital, 28034 Madrid, Spain
    Am J Respir Crit Care Med 181:983-91. 2010
  9. doi request reprint [Risk factors in chronic thromboembolic pulmonary hypertension]
    David Jimenez
    Servicio de Neumologia, Hospital Ramon y Cajal, Madrid, Espana
    Arch Bronconeumol 45:11-4. 2009
  10. doi request reprint Simplification of the pulmonary embolism severity index for prognostication in patients with acute symptomatic pulmonary embolism
    David Jimenez
    Respiratory Department, Hospital Ramón y Cajal and Alcalá de Henares University, 28034 Madrid, Spain
    Arch Intern Med 170:1383-9. 2010

Collaborators

Detail Information

Publications31

  1. ncbi request reprint Troponin I and risk stratification of patients with acute nonmassive pulmonary embolism
    D Jimenez
    Dept of Respiratory, Ramon y Cajal Hospital, Madrid, Spain
    Eur Respir J 31:847-53. 2008
    ..In conclusion, in haemodynamically stable patients with acute pulmonary embolism, cardiac troponin I was not an independent predictor of 30-day all-cause mortality, although it did predict fatal pulmonary embolism...
  2. doi request reprint Prognostic significance of multidetector computed tomography in normotensive patients with pulmonary embolism: rationale, methodology and reproducibility for the PROTECT study
    David Jimenez
    Respiratory Department, Ramon y Cajal Hospital, IRYCIS, 28034, Madrid, Spain
    J Thromb Thrombolysis 34:187-92. 2012
    ..730. Intraobserver reproducibility was very good (0.932, 95 % CI, 0.880-0.962). The PROTECT study is designed to show the prognostic significance of MDCT for PE. Inter- and intraobserver agreement of interpretation of RVD were good...
  3. doi request reprint Apixaban: an oral direct factor-xa inhibitor
    David Jimenez
    Respiratory Department, Ramon y Cajal Hospital, Madrid, Spain
    Adv Ther 29:187-201. 2012
    ..Ongoing phase 3 trials will provide data regarding the efficacy and safety of apixaban for treatment of acute deep vein thrombosis and pulmonary embolism...
  4. doi request reprint Prognostic models for selecting patients with acute pulmonary embolism for initial outpatient therapy
    David Jimenez
    Respiratory Department and Medicine Department, Ramón y Cajal Hospital and Alcalá de Henares University, Madrid, Spain
    Curr Opin Pulm Med 14:414-21. 2008
    ....
  5. ncbi request reprint [Anti-factor Xa activity of enoxaparin for thromboprophylaxis in nonsurgical patients is dependent on body mass]
    David Jimenez
    Servicio de Neumología Hospital Ramón y Cajal Madrid España
    Arch Bronconeumol 44:660-3. 2008
    ....
  6. doi request reprint Troponin-based risk stratification of patients with acute nonmassive pulmonary embolism: systematic review and metaanalysis
    David Jimenez
    Respiratory Department, Ramon y Cajal Hospital, 28034 Madrid, Spain
    Chest 136:974-82. 2009
    ..The sources of our data were publications listed in Medline and Embase from 1980 through April 2008 and a review of cited references in those publications...
  7. doi request reprint Association of anaemia and mortality in patients with acute pulmonary embolism
    David Jimenez
    Respiratory Department, Ramon y Cajal Hospital, Madrid, Spain
    Thromb Haemost 102:153-8. 2009
    ..99; p = 0.04). Moreover, patients with anaemia showed a higher risk of fatal PE (unadjusted HR 1.19, 95% CI 1.04 to 1.37). In conclusion, in patients with acute symptomatic PE, anaemia severity is associated with worsened survival...
  8. doi request reprint Prognostic significance of deep vein thrombosis in patients presenting with acute symptomatic pulmonary embolism
    David Jimenez
    Respiratory Department, Ramon y Cajal Hospital, 28034 Madrid, Spain
    Am J Respir Crit Care Med 181:983-91. 2010
    ..Concomitant deep vein thrombosis (DVT) in patients with acute pulmonary embolism (PE) has an uncertain prognostic significance...
  9. doi request reprint [Risk factors in chronic thromboembolic pulmonary hypertension]
    David Jimenez
    Servicio de Neumologia, Hospital Ramon y Cajal, Madrid, Espana
    Arch Bronconeumol 45:11-4. 2009
    ..Identification of new predisposing factors will provide clues to the pathogenic mechanisms of the disease and will facilitate early diagnosis and more effective treatment...
  10. doi request reprint Simplification of the pulmonary embolism severity index for prognostication in patients with acute symptomatic pulmonary embolism
    David Jimenez
    Respiratory Department, Hospital Ramón y Cajal and Alcalá de Henares University, 28034 Madrid, Spain
    Arch Intern Med 170:1383-9. 2010
    ..The Pulmonary Embolism Severity Index (PESI) estimates the risk of 30-day mortality in patients with acute pulmonary embolism (PE). We constructed a simplified version of the PESI...
  11. doi request reprint Risk stratification of normotensive patients with acute symptomatic pulmonary embolism
    David Jimenez
    Respiratory Department and Medicine Department, Ramón y Cajal Hospital and Alcalá de Henares University, IRYCIS, Madrid, Spain
    Br J Haematol 151:415-24. 2010
    ..Recommendations for outpatient treatment or thrombolytic therapy for patients with PE necessitate further development of prognostic models and conduct of clinical trials that assess various treatment strategies...
  12. doi request reprint Combinations of prognostic tools for identification of high-risk normotensive patients with acute symptomatic pulmonary embolism
    David Jimenez
    Respiratory Department, Ramon y Cajal Hospital, IRYCIS, Madrid, Spain
    Thorax 66:75-81. 2011
    ....
  13. ncbi request reprint [Prognostic value of transthoracic echocardiography in hemodynamically stable patients with acute symptomatic pulmonary embolism]
    David Jimenez
    Servicio de Neumologia, Hospital Ramon y Cajal, Madrid, Espana
    Arch Bronconeumol 43:490-4. 2007
    ..To determine the prognostic value of transthoracic echocardiography in hemodynamically stable patients diagnosed with acute symptomatic pulmonary embolism...
  14. ncbi request reprint Prognostic models for selecting patients with acute pulmonary embolism for initial outpatient therapy
    David Jimenez
    Respiratory Department Ramón y Cajal Hospital, Department of Medicine, Alcala de Henares University, 28034 Madrid, Spain
    Chest 132:24-30. 2007
    ..To assess the performance of two prognostic models in predicting short-term mortality in patients with pulmonary embolism (PE)...
  15. ncbi request reprint Diagnostic value of adenosine deaminase in nontuberculous lymphocytic pleural effusions
    D Jimenez Castro
    Emergency Dept, Ramon y Cajal Hospital, Madrid, Spain
    Eur Respir J 21:220-4. 2003
    ..Adenosine deaminase1/adenosine deaminase(p) correctly classified all nontuberculous lymphocytic pleural effusions with high adenosine deaminase levels...
  16. ncbi request reprint Prognostic features of residual pleural thickening in parapneumonic pleural effusions
    D Jimenez Castro
    Respiratory Dept, Zarzuela Clinic, Madrid, Spain
    Eur Respir J 21:952-5. 2003
    ..There are certain risk factors for the development of residual pleural thickening. However, this complication was not associated with long-term functional repercussions in the series of patients involved in this study...
  17. ncbi request reprint [Prognostic value of syncope in the presentation of pulmonary embolism]
    D Jimenez
    Servicio de Neumologia, Hospital Ramon y Cajal, Madrid, Spain
    Arch Bronconeumol 41:385-8. 2005
    ..The objective of this study was to carry out a prospective evaluation of the risk of recurrence and/or death in patients with pulmonary embolism that presents with syncope...
  18. ncbi request reprint Etiology and prognostic significance of massive pleural effusions
    David Jimenez
    Respiratory Department, Ramon y Cajal Hospital, Colmenar Road, Km 9, 100, 28034 Madrid, Spain
    Respir Med 99:1183-7. 2005
    ..Massive malignant pleural effusions are associated with worse survival, independent of age and histologic subgroup, than are non-massive malignant pleural effusions...
  19. ncbi request reprint Pleural fluid parameters identifying complicated parapneumonic effusions
    D Jimenez Castro
    Respiratory Department, Hospital Ramon y Cajal, Alcala de Henares University, Madrid, Spain
    Respiration 72:357-64. 2005
    ..Controversy exists regarding the clinical utility of pleural fluid parameters as prognosticators of complicated parapneumonic effusions that require drainage...
  20. ncbi request reprint The risk of recurrent venous thromboembolism in patients with unprovoked symptomatic deep vein thrombosis and asymptomatic pulmonary embolism
    David Jimenez
    Respiratory Department, Ramon y Cajal Hospital, Madrid, Spain
    Thromb Haemost 95:562-6. 2006
    ..0045). In patients with a first episode of unprovoked symptomatic acute proximal lower extremity DVT, the risk of recurrent VTE was significantly higher in those with silent PE compared to those without PE...
  21. ncbi request reprint Routine use of pleural fluid cultures. Are they indicated? Limited yield, minimal impact on treatment decisions
    D Jimenez
    Respiratory Department, Hospital Ramon y Cajal, Madrid, Spain
    Respir Med 100:2048-52. 2006
    ..In conclusion, this study demonstrates that, at least in our institution, routine microbial investigation of pleural fluid adds very little to the standard management of parapneumonic effusions...
  22. ncbi request reprint Diagnostic value of D dimer in pulmonary embolism and pneumonia
    D J Castro
    Servicio de Urgencias, Hospital Ramon y Cajal, E 28080 Madrid, Spain
    Respiration 68:371-5. 2001
    ..High plasmatic levels of D dimer (DD), a specific fibrin derivate, have recently been reported in PE...
  23. ncbi request reprint Prognostic significance of delays in diagnosis of pulmonary embolism
    David Jiménez Castro
    Respiratory Division, Medicine Department, Ramon y Cajal Hospital, Alcala de Henares University, 28034 Madrid, Spain
    Thromb Res 121:153-8. 2007
    ..To investigate the prognostic significance of a diagnostic delay of greater than 1 week after symptom onset in patients with pulmonary embolism (PE)...
  24. ncbi request reprint Monotherapy with enoxaparin for the prevention of recurrent venous thromboembolism
    David Jiménez Castro
    Respiratory Department, Hospital Ramon y Cajal, Madrid
    Blood Coagul Fibrinolysis 18:173-7. 2007
    ..0001). Enoxaparin is as effective and safe as acenocoumarol in the secondary prevention of recurrent thromboembolic disease and is associated with shorter hospitalization...
  25. ncbi request reprint [Thromboembolic events in patients after a negative computed tomography pulmonary angiogram: A retrospective study of 165 patients]
    David Jimenez
    Servicio de Neumología Hospital Ramón y Cajal Madrid España
    Arch Bronconeumol 42:344-8. 2006
    ..To determine the value of computed tomography (CT) angiography of the chest as a diagnostic test to exclude pulmonary embolism and to assess compliance with diagnostic protocols for thromboembolic disease...
  26. doi request reprint The shock index and the simplified PESI for identification of low-risk patients with acute pulmonary embolism
    A Sam
    Respiratory Dept and Medicine Dept, Ramón y Cajal Hospital and Alcalá de Henares University, 28034 Madrid, Spain
    Eur Respir J 37:762-6. 2011
    ..2-4.4%)). The net reclassification improvement with the sPESI was 13.4% (p = 0.07). The integrated discrimination improvement was estimated as 1.8% (p<0.001). The sPESI quantified the prognosis of patients with PE better than the SI...
  27. ncbi request reprint Short-term clinical outcome after acute symptomatic pulmonary embolism
    Francisco Conget
    Department of Medicine, Psychiatry and Dermatology, Lozano Blesa Hospital and Zaragoza University, Zaragoza, Spain
    Thromb Haemost 100:937-42. 2008
    ..Patients with systolic arterial hypotension and immobilization at the time of PE diagnosis had an increased risk of short-term mortality...
  28. ncbi request reprint [A clinical prediction rule for identifying short-term risk of adverse events in patients with pulmonary thromboembolism]
    Fernando Uresandi
    Servicio de Neumologia, Hospital de Cruces, Barakaldo, Bizkaia, Espana
    Arch Bronconeumol 43:617-22. 2007
    ..To identify patients with a low short-term risk of complications following acute pulmonary thromboembolism...
  29. doi request reprint [Chronic obstructive pulmonary disease in patients with acute symptomatic pulmonary embolism]
    Carolina Fernandez
    Servicio de Neumologia, Hospital Ramon y Cajal, Madrid, Espana
    Arch Bronconeumol 45:286-90. 2009
    ..Some studies have suggested that patients with PE and concomitant COPD have a worse prognosis than patients without COPD...
  30. ncbi request reprint [Prognostic value of electrocardiographic findings in hemodynamically stable patients with acute symptomatic pulmonary embolism]
    Carlos Escobar
    Unidad de Ecocardiografía, Servicio de Cardiologia, Hospital Ramon y Cajal, Madrid, Espana
    Rev Esp Cardiol 61:244-50. 2008
    ..The aim of this study was to determine the prognostic value of electrocardiography in hemodynamically stable patients with a diagnosis of acute symptomatic pulmonary embolism (PE)...
  31. ncbi request reprint [Early complications in patients with pulmonary embolism]
    Dolores Nauffal
    Servicio de Neumologia, Hospital La Fe, Valencia, Espana
    Med Clin (Barc) 127:1-4. 2006
    ..Mortality, recurrences and hemorrhages are the most serious early complications of pulmonary embolism (PE). We intended to ascertain the frequency and mechanisms of complications within the first 10 days after PE was diagnosed...