Melissa K Carpenter

Summary

Publications

  1. doi request reprint Development. Deconstructing pluripotency
    Anne G Bang
    Novocell Inc, 3550 General Atomics Court, San Diego, CA 92121, USA
    Science 320:58-9. 2008
  2. doi request reprint Cell-surface markers for the isolation of pancreatic cell types derived from human embryonic stem cells
    Olivia G Kelly
    ViaCyte, Inc formerly Novocell, Inc, San Diego, California, USA
    Nat Biotechnol 29:750-6. 2011
  3. doi request reprint Pancreatic endoderm derived from human embryonic stem cells generates glucose-responsive insulin-secreting cells in vivo
    Evert Kroon
    Novocell, Inc, 3550 General Atomics Ct, San Diego, California 92121, USA
    Nat Biotechnol 26:443-52. 2008
  4. ncbi request reprint Production of pancreatic hormone-expressing endocrine cells from human embryonic stem cells
    Kevin A D'Amour
    Novocell Inc, 3550 General Atomics Ct, San Diego, California 92121, USA
    Nat Biotechnol 24:1392-401. 2006
  5. ncbi request reprint Immortalized fibroblast-like cells derived from human embryonic stem cells support undifferentiated cell growth
    Chunhui Xu
    Geron Corporation, 230 Constitution Drive, Menlo Park, California 94025, USA
    Stem Cells 22:972-80. 2004
  6. ncbi request reprint Basic fibroblast growth factor supports undifferentiated human embryonic stem cell growth without conditioned medium
    Chunhui Xu
    Geron Corporation, 230 Constitution Drive, Menlo Park, California 94025, USA
    Stem Cells 23:315-23. 2005
  7. ncbi request reprint Generation of hepatocyte-like cells from human embryonic stem cells
    Lakshmi Rambhatla
    Geron Corporation, 230 Constitution Drive, Menlo Park, CA 94025, USA
    Cell Transplant 12:1-11. 2003
  8. ncbi request reprint Human embryonic stem cell-derived cardiomyocytes can be maintained in defined medium without serum
    Chunhui Xu
    Geron Corporation, Menlo Park, CA 94025, USA
    Stem Cells Dev 15:931-41. 2006
  9. ncbi request reprint Characterization and culture of human embryonic stem cells
    Lisa M Hoffman
    Stem Cell Biology and Regenerative Medicine, Robarts Research Institute, 100 Perth Drive, London, Ontario N6A 5K8, Canada
    Nat Biotechnol 23:699-708. 2005
  10. ncbi request reprint Human embryonic stem cell stability
    Lisa M Hoffman
    Krembil Centre for Stem Cell Biology, Robarts Research Institute, London, Ontario, Canada
    Stem Cell Rev 1:139-44. 2005

Collaborators

  • Olivia G Kelly
  • Ralph Brandenberger
  • Mahendra Rao
  • Steve Goldman
  • Hans Keirstead
  • Chunhui Xu
  • Anne G Bang
  • Lisa M Hoffman
  • Takumi Miura
  • Evert Kroon
  • Kevin A D'Amour
  • Nora G Smart
  • Susan Eliazer
  • Alan D Agulnick
  • Emmanuel E Baetge
  • Holly Young
  • Gabriel I Nistor
  • Neeta S Roy
  • Yongquan Luo
  • Elen S Rosler
  • Irene Ginis
  • Lakshmi Rambhatla
  • Justine Cunningham
  • Mike Richardson
  • Laura A Martinson
  • Kuniko Kadoya
  • Mark A Moorman
  • Nadia Haque
  • Minodora O Totoiu
  • Joseph Itskovitz-Eldor
  • Ximena Ares
  • Weiguo Peng
  • Daixing Zhou
  • Michal Amit
  • R Scott Thies
  • Takahiro Nakano
  • Jane Lebkowski
  • Gregory J Fisk
  • M Lita Alonso
  • Tom Vasicek
  • Scott Thies
  • Irina Khrebtukova
  • H Michael Keyoung
  • John Irving
  • Maiken Nedergaard
  • Ahmet Hoke
  • Martha Windrem
  • Jane Lin
  • Sharon Gerecht-Nir
  • Jian Kang
  • William K Rashbaum
  • Yun Peng
  • Pratima Kundu
  • Choy Pik Chiu

Detail Information

Publications17

  1. doi request reprint Development. Deconstructing pluripotency
    Anne G Bang
    Novocell Inc, 3550 General Atomics Court, San Diego, CA 92121, USA
    Science 320:58-9. 2008
  2. doi request reprint Cell-surface markers for the isolation of pancreatic cell types derived from human embryonic stem cells
    Olivia G Kelly
    ViaCyte, Inc formerly Novocell, Inc, San Diego, California, USA
    Nat Biotechnol 29:750-6. 2011
    ..These antibodies will aid investigations that use pancreatic cells generated from pluripotent stem cells to study diabetes and pancreas biology...
  3. doi request reprint Pancreatic endoderm derived from human embryonic stem cells generates glucose-responsive insulin-secreting cells in vivo
    Evert Kroon
    Novocell, Inc, 3550 General Atomics Ct, San Diego, California 92121, USA
    Nat Biotechnol 26:443-52. 2008
    ..Together, these data provide definitive evidence that hES cells are competent to generate glucose-responsive, insulin-secreting cells...
  4. ncbi request reprint Production of pancreatic hormone-expressing endocrine cells from human embryonic stem cells
    Kevin A D'Amour
    Novocell Inc, 3550 General Atomics Ct, San Diego, California 92121, USA
    Nat Biotechnol 24:1392-401. 2006
    ..Production of these hES cell-derived endocrine cells may represent a critical step in the development of a renewable source of cells for diabetes cell therapy...
  5. ncbi request reprint Immortalized fibroblast-like cells derived from human embryonic stem cells support undifferentiated cell growth
    Chunhui Xu
    Geron Corporation, 230 Constitution Drive, Menlo Park, California 94025, USA
    Stem Cells 22:972-80. 2004
    ..These results suggest that immortalized cell lines can be generated from hESCs and that cells derived from hESCs can be used to support their own growth, creating a genotypically homogeneous system for the culture of hESCs...
  6. ncbi request reprint Basic fibroblast growth factor supports undifferentiated human embryonic stem cell growth without conditioned medium
    Chunhui Xu
    Geron Corporation, 230 Constitution Drive, Menlo Park, California 94025, USA
    Stem Cells 23:315-23. 2005
    ..These data demonstrate that hESCs can be maintained in nonconditioned medium using growth factors...
  7. ncbi request reprint Generation of hepatocyte-like cells from human embryonic stem cells
    Lakshmi Rambhatla
    Geron Corporation, 230 Constitution Drive, Menlo Park, CA 94025, USA
    Cell Transplant 12:1-11. 2003
    ..Because of the inherent proliferative capacity of hES cells, these cells may provide a reliable source of normal human hepatocytes for research and transplantation...
  8. ncbi request reprint Human embryonic stem cell-derived cardiomyocytes can be maintained in defined medium without serum
    Chunhui Xu
    Geron Corporation, Menlo Park, CA 94025, USA
    Stem Cells Dev 15:931-41. 2006
    ..Therefore, culturing hES cell-derived cardiomyocytes in serum-free medium as described here should facilitate the use of the cells for in vitro and in vivo applications...
  9. ncbi request reprint Characterization and culture of human embryonic stem cells
    Lisa M Hoffman
    Stem Cell Biology and Regenerative Medicine, Robarts Research Institute, 100 Perth Drive, London, Ontario N6A 5K8, Canada
    Nat Biotechnol 23:699-708. 2005
    ..It will therefore be important to define robust criteria for the assessment of both existing and newly derived cell lines and for the validation of new culture conditions...
  10. ncbi request reprint Human embryonic stem cell stability
    Lisa M Hoffman
    Krembil Centre for Stem Cell Biology, Robarts Research Institute, London, Ontario, Canada
    Stem Cell Rev 1:139-44. 2005
    ..Because of the potential utility of hESCs, it will be of utmost importance to evaluate the stability of these aspects of ESC biology...
  11. ncbi request reprint Monitoring early differentiation events in human embryonic stem cells by massively parallel signature sequencing and expressed sequence tag scan
    Takumi Miura
    Gerontology Research Center, Stem Cell Biology Unit Laboratory of Neurosciences, National Institute on Aging, National Institutes of Health, Baltimore, MD 21224, USA
    Stem Cells Dev 13:694-715. 2004
    ..The data generated can be used to monitor the state of hESC isolated by different laboratories using independent methods and maintained under differing culture conditions...
  12. ncbi request reprint Human embryonic stem cells differentiate into oligodendrocytes in high purity and myelinate after spinal cord transplantation
    Gabriel I Nistor
    Reeve Irvine Research Center, Department of Anatomy and Neurobiology, 2111 Gillespie Neuroscience Research Facility, Gillespie Neuroscience Research Facility, College of Medicine, University of California at Irvine, Irvine, CA 92697, USA
    Glia 49:385-96. 2005
    ....
  13. ncbi request reprint Differences between human and mouse embryonic stem cells
    Irene Ginis
    Stem Cell Section, Laboratory of Neurosciences, National Institute on Aging, NIH, Baltimore, MD 21224, USA
    Dev Biol 269:360-80. 2004
    ..2) and to feeder-free subclones of H1, H7, and H9, indicating that the observed differences between human and mouse ES cells were species-specific rather than arising from differences in culture conditions...
  14. ncbi request reprint Telomerase immortalization of neuronally restricted progenitor cells derived from the human fetal spinal cord
    Neeta S Roy
    Department of Neurology and Neuroscience, Cornell University Medical Center, New York, New York 10021, USA
    Nat Biotechnol 22:297-305. 2004
    ..The cells have survived >168 doublings in vitro, with karyotypic normalcy and without replicative senescence. hTERT overexpression thus permits the generation of progenitor lines able to give rise to phenotypically restricted neurons...
  15. ncbi request reprint Long-term culture of human embryonic stem cells in feeder-free conditions
    Elen S Rosler
    Geron Corporation, Menlo Park, California, USA
    Dev Dyn 229:259-74. 2004
    ....
  16. ncbi request reprint Properties of four human embryonic stem cell lines maintained in a feeder-free culture system
    Melissa K Carpenter
    Geron Corporation, Menlo Park, California, USA
    Dev Dyn 229:243-58. 2004
    ..These data provide the first detailed comparison of different hES cell lines and demonstrate remarkable similarities among lines maintained in identical culture conditions...
  17. ncbi request reprint Characterization and enrichment of cardiomyocytes derived from human embryonic stem cells
    Chunhui Xu
    Geron Corporation, Menlo Park, Calif 94025, USA
    Circ Res 91:501-8. 2002
    ..The extended replicative capacity of hES cells and the ability to differentiate and enrich for functional human cardiomyocytes warrant further development of these cells for clinical application in heart diseases...