Andres A Caro

Summary

Publications

  1. doi request reprint Prooxidant and antioxidant properties of salicylaldehyde isonicotinoyl hydrazone iron chelators in HepG2 cells
    Andres A Caro
    Chemistry Department, Hendrix College, Conway, AR 72032, USA Electronic address
    Biochim Biophys Acta 1850:2256-64. 2015
  2. pmc Effect of garlic-derived organosulfur compounds on mitochondrial function and integrity in isolated mouse liver mitochondria
    Andres A Caro
    Chemistry Department, Hendrix College, Conway, AR, United States
    Toxicol Lett 214:166-74. 2012
  3. pmc CYP2E1 overexpression inhibits microsomal Ca2+-ATPase activity in HepG2 cells
    Andres A Caro
    Hendrix College, Chemistry Department, 1600 Washington Avenue, Conway, AR 72032, USA
    Toxicology 255:171-6. 2009
  4. pmc Increased oxidative stress and cytotoxicity by hydrogen sulfide in HepG2 cells overexpressing cytochrome P450 2E1
    Andres A Caro
    Chemistry Department, Hendrix College, Conway, AR 72032, USA
    Cell Biol Toxicol 27:439-53. 2011

Detail Information

Publications4

  1. doi request reprint Prooxidant and antioxidant properties of salicylaldehyde isonicotinoyl hydrazone iron chelators in HepG2 cells
    Andres A Caro
    Chemistry Department, Hendrix College, Conway, AR 72032, USA Electronic address
    Biochim Biophys Acta 1850:2256-64. 2015
    ..Because the liver is the major site of iron storage, elucidating the effect of SIH on hepatic oxidative metabolism is critical for designing effective hepatic antioxidant therapies...
  2. pmc Effect of garlic-derived organosulfur compounds on mitochondrial function and integrity in isolated mouse liver mitochondria
    Andres A Caro
    Chemistry Department, Hendrix College, Conway, AR, United States
    Toxicol Lett 214:166-74. 2012
    ..These results suggest that DADS causes direct impairment of mitochondrial function as the result of oxidation of the membrane lipid phase initiated by the GSH- and iron-dependent generation of oxidants...
  3. pmc CYP2E1 overexpression inhibits microsomal Ca2+-ATPase activity in HepG2 cells
    Andres A Caro
    Hendrix College, Chemistry Department, 1600 Washington Avenue, Conway, AR 72032, USA
    Toxicology 255:171-6. 2009
    ..This may contribute to elevated cytosolic calcium and to CYP2E1-potentiated injury...
  4. pmc Increased oxidative stress and cytotoxicity by hydrogen sulfide in HepG2 cells overexpressing cytochrome P450 2E1
    Andres A Caro
    Chemistry Department, Hendrix College, Conway, AR 72032, USA
    Cell Biol Toxicol 27:439-53. 2011
    ..These data suggest that CYP2E1 enhances H(2)S-dependent cytotoxicity in HepG2 cells through the generation of iron-dependent oxidative stress and lipid peroxidation...